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Antimalarial medicinal plants
Malaria continues to affect a large population of the world, especially in third world countries. The spread of drug-resistant parasites demonstrates the need for antimalarial agents with various modes of action. The search for remedies derived from medicinal plants for the treatment of malaria is reliant on accurate ethnobotanical and ethnopharmacological information obtained from traditional medical practitioners. Antimalarial Medicinal Plants provides information on bioactive compounds and therapeutic potentials of several antimalarial plant species found around the globe. This book evaluates these plant species with respect to their biology, diversity, distribution, and pharmacological values.
Antifouling Compounds
Increasing awareness of the deleterious effects of toxic components in antifouling coatings has raised interest in the potential for nontoxic alternatives. This book examines how marine organisms from bacteria to invertebrates and plants use chemicals to communicate and defend themselves. Chemicals that prevent colonisation of living surfaces are particularly pertinent to antifouling technology and may inspire new solutions. The challenge is to identify such compounds, identify the means for sustainable production and incorporate them into coatings to give long-term antifouling efficacy.
Antidiabetic plants for drug discovery pharmacology, secondary metabolite profiling, and ingredients with insulin mimetic activity
Takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs. Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology.
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
Antibody-drug conjugates and cellular metabolic dynamics
Summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs.
Antibiotics : Methods and protocols
Provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols, Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Antibiotic policies : Theory and practice
This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries
Antibiotic Policies : Fighting Resistance
This book addresses many of the key issues taxing our society and hospitals in an era of epidemic resistance and shortage of new antibiotics. Written by internationally renowned experts in the field, this volume will provide practical advice and inform control strategies for the most urgent of problems related to antibiotic resistance epidemic for years to come. Antibiotic Policies: Fighting Resistance is an ideal volume for health professionals with an interest in this field.
Antiangiogenic Agents in Cancer Therapy
Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.
Anthropologies of Global Maternal and Reproductive Health : From Policy Spaces to Sites of Practice
This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors – both internationally respected anthropologists and new voices – demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals’ and lay people’s intimate encounters with policy.
Antarctic ecosystems : Environmental contamination, climate change, and human impact
This volume provides an overview of climate change data, its effects on the structure and functioning of Antarctic ecosystems, and the occurrence and cycling of persistent contaminants. It discusses the unique physico-chemical characteristics of the Antarctic environment, ecophysiological adaptations of terrestrial and marine organisms, the transfer of contaminants in pelagic and neritic food chains and the possible consequences for animals at higher trophic levels.
Anisotropy Across Fields and Scales
This book focuses on processing, modeling, and visualization of anisotropy information…
Animals and the shaping of modern medicine : One health and its histories
This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and reveals that what we think of as ‘human’ medicine was in fact deeply zoological.Each chapter analyses an important episode in which animals changed and were changed by medicine. Ranging across the animal inhabitants of Britain’s zoos, sick sheep on Scottish farms, unproductive livestock in developing countries, and the tapeworms of California and Beirut, they illuminate the multi-species dimensions of modern medicine and its rich historical connections with biology, zoology, agriculture and veterinary medicine. The modern movement for One Health – whose history is also analyzed – is therefore revealed as just the latest attempt to improve health by working across species and disciplines.
Animal cell technology meets genomics ; Proceedings of the 18th ESACT Meeting. Granada, Spain, May 11-14, 2003
Reflects the spirit and scientific excellence of the 18th ESACT meeting in different chapters. This book presents, in form of short papers, a high number of the contributions to the meeting, and has been prepared with the aim to provide a relevant reference of the research efforts in Animal Cell Technology
Animal cell technology : Basic & applied aspects ; Proceedings of the 7th Annual Meeting of the Japanese Association for animal cell technology (JAACT), Nagoya, Japan, November 15-18, 2004
This book contains the proceedings of the 17th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT) that was held in Nagoya, Japan from November 15 to 18, 2004. This volume gives the readers a complete review of present state-of-the-art in Japan and other countries where this field is well advanced. The Proceedings will be useful for the cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and other disciplines related to animal cell culture, working in either academic environments or in industries of biotechnology and pharmacy.
Angiogenesis in Inflammation : Mechanisms and Clinical Correlates
This volume relates the lessons learned from tumour biology applied to inflammation. This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.
Ane's Encyclopedic Dictionary of General & Applied Entomology
Keeping the requirements of teachers and researchers in mind, this encyclopedic dictionary presents the terminology in entomology and pest management in the most authentic and comprehensive way. It also includes terms related to the close relatives of insects, such as mites and ticks and some other organisms which are pests of crops.
Anatomy ontologies for bioinformatics : Principles and practice
This book provides a timely and first-of-its-kind collection of contributed chapters on anatomy ontologies. It is interdisciplinary in its approach, bringing together relevant expertise from computing and biomedical studies, and covering both theoretical and applied aspects, with an emphasis on newer work relevant to the emerging Semantic Web.
Anatomy for Dental Medicine
Strikes an optimal balance between systemic and regional approaches to complex head and neck anatomy. Award-winning full-color illustrations, succinct text, summary tables, and questions put anatomical structures and knowledge into a practical context. NEW! Additional radiologic images and landmark features throughoutNEW! Reorganized brain/nerve sectionsNEW! Expanded clinical question appendix including patient box questions in the style of the INBDENEW! Factual question appendix places greater emphasis on areas including the skull, larynx, cross sectional anatomy, body below the neck, and local anesthesia
Anatomy : Regional, Surgical, and Applied
Presents a concise, accessible guide to regional and clinically applied anatomy, which clearly demonstrates to students the level of knowledge required for medical and healthcare-related curricula / Uses high-quality clinical and intraoperative images integrated into the text to emphasizes important topics through bullet points / Features logically arranged sections, each devoted to a body region or system, which includes a self-test quiz, with the single best answer and spotter-style questions
