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Bone densitometry for technologists
Radiologic technologists, nurse practitioners, physician assistants, and dedicated densitometry technologists can find new guidelines for bone density testing, new therapies for osteoporosis, and new treatment guidelines for osteoporosis, as well as new chapters on pediatric densitometry body composition assessments, and the use of skeletal morphometry in diagnosis and fracture risk prediction. The twelve appendices have also been updated to reflect the most current information available, including contacts for densitometry equipment manufacturers and organizations, guidelines for bone density testing and CPT codes, definitions of terms, and new conversion equations.
Bioterrorism and Infectious Agents : A New Dilemma for the 21st Century
Since the terrorist attack on the United States on September 11, 2001 and subsequent cases of anthrax in Florida and New York City, attention has been focused on the threat of b- logical warfare and bioterrorism. Biological warfare agents are de?ned as “living org- isms, whatever their nature, or infected material derived from them, which are used for h- tile purposes and intended to cause disease or death in man, animals and plants, and depend for their efforts on the ability to multiply in person, animal or plant attacked.” Biological warfare agents may be well suited for bioterrorism to create havoc and terror in a civilian population, because they are cheap and easy to obtain and dispense. Infectious or contagious diseases have played a major part in the history of warfare – deliberately or inadvertently – in restricting or assisting invading armies over the centuries. In 1346, the Tartars catapulted plaque-infected bodies into Kaffa in the Crimea to end a 3-year siege. Blankets contaminated with smallpox to infect North American Indians were used by British forces in the 18th century. More recently, the Japanese released ?eas infected with plaque in Chinese cities in the 1930s and 1940s. Biological research programs for both offensive and defensive strategies have been developed by the United States, Britain, the former Soviet Union, and Canada; several other nations are thought to have such programs.
Biotechnologies for plant mutation breeding : Protocols
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.
Biosphere Origin and Evolution
The book covers notions by scientists of various branches on the evolutionary relationship between the biosphere and geosphere, evolution features at various levels of living matter organization, and problems of prebiotic evolution and life origin. The data were collected in the course of the RAS program "Biosphere origin and evolution" (subprogram II) in 2003–2006. The objectives of this subprogram were (1) generalization of data related to problems of biosphere origin and evolution accumulated by geneticists, molecular biologists, zoologists, botanists, paleontologists, microbiologists, geologists, chemists, and archaeologists; (2) search for new interdisciplinary approaches to biosphere origin and evolution; (3) development of a "lingua franca" understandable by experts in various fields, which would allow apprehension of results concerning the topic obtained in allied sciences
Biophysical Techniques in Photosynthesis ; Vol. II
Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume (Volume 3 in the Series) by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis. The contributions are written by leading scientists in their field. The book has 5 sections: Imaging; Structure; Optical and laser spectroscopy; Magnetic resonance; Theory. Each chapter describes the basic concepts of the technique, practical applications and scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but also to assess the resources that are required for implementation. The book is intended for use by graduate students and researchers in photosynthesis as well as in (bio)physics, (bio)chemistry and biology in general.
Biopharmaceutics applications in drug development
This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.
Biopharmaceutical drug design and development
Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.
Biomolecular and bioanalytical techniques : Theory, methodology and applications
Offers an introduction to, and a basic understanding of, a wide range of biophysical techniques. The text takes an interdisciplinary approach with contributions from a panel of distinguished experts. With a focus on research, the text comprehensively covers a broad selection of topics drawn from contemporary research in the fields of chemistry and biology. Each of the internationally reputed authors has contributed a single chapter on a specific technique. The chapters cover the specific technique’s background, theory, principles, technique, methodology, protocol and applications.
Biomarkers for alzheimer’s disease drug development
Aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Biology of Inositols and Phosphoinositides
This volume describes the current status of the biology of inositols and phosphoinositides with an emphasis on the development in the area since the publication of volume 26 in 1996 in this series. The progress made in dissecting the genetics, structure and evolution of the seminal enzyme for synthesis of inositol in the biological system has driven the understanding of the enzyme forward. With the current genomic and proteomic tools in place the new role of inositols, inositol phosphates and phosphoinositides in cell signaling or stress response has been explored. These advances are described.
Biology and Ecology of Norway Spruce
This book presents a concise and comprehensive review of the biology, ecology, and management of Norway spruce. It integrates classic and contemporary literature (more than 2000 works cited in the text), highlighting basic research and forestry practices in central and eastern Europe. The topics include anatomy and morphology, physiology and nutrition, reproductive biology and genetics, and ecology. In addition, it examines mycorrhiza, diseases and pests as well as silviculture and wood products. In the light of increasing threats to forest health from air pollution, climate change, and insects and disease, it provides an essential information source to those concerned with the ecology, conservation, and management of the species
Biologics, biosimilars, and biobetters : An introduction for pharmacists, physicians and other health practitioners
Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists
Biological nitrogen fixation, sustainable agriculture and the environment ; Proceedings of the 14th International nitrogen fixation congress
Covers aspects of fundamental and applied nitrogen-fixation research, from biochemistry and chemistry through genetics, regulation and physiology to agricultural practice and environmental impact. This work describes progress on studies of potential catalysts for nitrogen fixation; how the N2-fixing process is regulated in living cells; and more.
Biological Invasions
This new volume on Biological Invasions deals with both plants and animals. It differs from previous books on the subject by extending from the level of individual species to an ecosystem and global level. Topics of highest societal relevance, such as the impact of genetically modified organisms, are interlinked with more conventional ecological aspects, including biodiversity. The combination of these approaches is new and makes compelling reading for researchers and environmentalists. The book’s 22 chapters cover a huge range of subjects relevant to the field. These include pathways of biological invasions (e.g. ballast water, waterways), traits of successful invaders (e.g. chemical weapons, empty niches), and patterns of invasion and invasibility, such as man-induced predisposition by fire, land use and eutrophication, and the role of climate change.
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Bioinformatics drug discovery
Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.
Bioinformatics and the cell : Modern computational approaches in genomics, proteomics and transcriptomics
"Xuhua Xia’s Bioinformatics and the Cell is a welcome addition to the bourgeoning field of bioinformatics text books. Xia stakes out a too-often neglected middle ground in bioinformatics by presenting a work that emphasizes methods’ biological utility without eschewing algorithmic formalism. Readers will find a well-rounded presentation of bioinformatics techniques employed in genomics, transcriptomics and proteomics – unified throughout by the common theme of molecular evolution."
Bioethics in Law
The idea for Bioethics in Law began more than a decade ago, while I was studying social science and law. I was parti- larly interested in the collaborations that comprised social s- ence in law. Economic and social data in the pioneering Brandeis brief had been used to defend an early 20th-century labor law; surveys of consumer confusion had helped resolve trademark - fringement cases; psychologists’ predictions of future violence had informed capital sentencing decisions. Additionally, Kenneth Clark’s “doll studies,” cited by the Supreme Court in Brown v. Board of Education, had helped change the course of American 1 history.
Bioethics and the Holocaust : A Comprehensive Study in How the Holocaust Continues to Shape the Ethics of Health, Medicine and Human Rights
This book offers a framework for understanding how the Holocaust has shaped and continues to shape medical ethics, health policy, and questions related to human rights around the world. The field of bioethics continues to face questions of social and medical controversy that have their roots in the lessons of the Holocaust, such as debates over beginning-of-life and medical genetics, end-of-life matters such as medical aid in dying, the development of ethical codes and regulations to guide human subject research, and human rights abuses in vulnerable populations. As the only example of medically sanctioned genocide in history, and one that used medicine and science to fundamentally undermine human dignity and the moral foundation of society, the Holocaust provides an invaluable framework for exploring current issues in bioethics and society today. This book, therefore, is of great value to all current and future ethicists, medical practitioners and policymakers – as well as laypeople.
Bioelectromagnetics current concepts : The mechanisms of the biological effect of extremely high power pulses
Proceedings of the NATO Advanced Research Workshop on The Mechanisms of the Biological Effect on Extra High Power Pulses (EHPP), Yerevan, Armenia 3 - 5 March 2005
