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New Frontiers in Regenerative Medicine

Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. Areas of focus include the nervous system and hippocampal neurogenesis, along with the functional significance of pro-inflammatory cytokines, and the production of free radicals after brain ischemia; the digestive and integumentary systems, dealing with hepatocyte transplantation, pancreatic regeneration, and skin and hair regeneration; and the cardiovascular system, with repair and remodeling of the lung and heart, and arterial remodeling with bone marrow-derived progenitor cells. In addition to animal experiments, results of research on human tissues and organs are included.

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New Frontiers in Lifestyle-Related Diseases

Akiyoshi Hosoyamada, M.D., Ph.D. President, Showa University Tokyo, Japan September 2007 v Preface The leading cause of death in Western countries and some developing countries is atherosclerotic cardiovascular diseases. Among them, acute myocardial infarction is the most common type of fatal disease, caused by the progression of atherosclerosis characterized by accumulation of choles­ terol in vascular walls. Development of atherosclerosis is greatly enhanced by major risk factors for cardiovascular diseases such as obesity, hyperlip­ idemia, diabetes (hyperglycemia), and hypertension. Among those, obesity frequently initiates a metabolic change that subsequently induces hyperlip­ idemia, diabetes, hypertension, and eventually atherosclerotic cardiovascu­ lar diseases. Because obesity and its related disorders largely depend on lifestyle factors such as high calorie intake and low physical activity, a series of disorders are termed lifestyle-related diseases.

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New frontiers in artificial intelligence ; JSAI-isAI International Workshops, JURISIN, AI-Biz, LENLS, Kansei-AI, Yokohama, Japan, November 10–12, 2019, Revised Selected Papers

This book constitutes extended, revised and selected papers from the 11th International Symposium of Artificial Intelligence supported by the Japanese Society for Artificial Intelligence, JSAI-isAI 2019. It was held in November 2019 in Yokohama, Japan. The 26 papers were carefully selected from 46 submissions and deal with topics of AI research and are organized into 4 sections, according to the 4 workshops: JURISIN 2019, AI-Biz 2019, LENLS 16, and Kansei-AI 2019.

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New Frontiers in Artificial Intelligence ; Joint JSAI 2005 Workshop Post-Proceedings

The objectives of this book are to present the award papers from the 19th annual conference of JSAI 2005 and the selected papers from the ?ve co-located international workshops and to promote the study exchange among worldwide researchers. Five papers received awards among more than 200 presentations in the conference, and 40 papers were selected from the workshops of Logic and Engineering of Natural Language Semantics 2005 (LENLS 2005), Learning with Logics and Logics for Learning (LLLL 2005), Agent Network Dynamics and Intelligence (ANDI 2005), Conversational Informatics (CI 2005) and Risk Management Systems with Intelligent Data Analysis (RMSIDA 2005).

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New Frontiers in Angiogenesis

New Frontiers in Angiogenesis starts with a comprehensive overview of the field and continues with topics that have been minimally explored. The topics deal with dynamics of vasculogenesis using imaging techniques, bone marrow-derived endothelial cell precursors as potential therapeutic tools, regulation of post-angiogenic vessel regression, vascular mimicry, design and construction of artificial vessels, bioengineering of angiogenesis, and lymphangiogenesis recapitulating angiogenesis in health and disease states. Each chapter is written by leading experts of the subjects. It is hoped that this volume will challenge all of us interested in the field of angiogenesis and cardiovascular biology, in particular those in academia and industries, to think "outside the box" and explore angiogenesis from a fresh angle. It is hoped that New Frontiers in Angiogenesis is thought provoking and serve as a road map for discovering new findings to help betterments of human health.

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New Design for Old Buildings

Explores design, materials and technical considerations in creating the best low energy, ecological and sustainable retrofits. It has never been more important to understand how old buildings can be adapted to make them useful and sustainable in the future. Showcasing the best examples of imaginative design and best practice, this book illustrates how old buildings can be made sustainable through the best new design and puts these design exemplars into a historical and philosophical context. With illustrative case studies and interviews throughout, including formal buildings, churches, domestic buildings, commercial, industrial and agricultural from all periods in the UK, New Design for Old Buildings provides essential guidance on good, imaginative new design for old buildings.

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New Challenges in Gastrointestinal Endoscopy

Gastrointestinal (GI) endoscopy has become indispensable in both diagnosis and treatment of GI disorders. It has been 10 years now since the first Endoscopy Forum Japan was held, and in that time, leading young endoscopists, including colleagues from Asia, Australia, Europe, and the United States, have participated in the forum, discussing issues at the forefront of the field. Through their efforts, GI endoscopy has advanced with many new methods for both diagnoses and treatments, and those achievements are included in this book. Contributing to the development of endoscopic medicine all over the world, this is a groundbreaking, edifying, and engrossing publication offering the most recent advances in the field, precisely presented and depicted with more than 250 color photographs. Novel technologies are described in detail and will be of interest to those in the field of medicine and in engineering as well.

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New Carbon Based Materials for Electrochemical Energy Storage Systems : Batteries, Supercapacitors and Fuel Cells

This NATO-ARW volume contains a diverse collection of papers addressing the role of carbon in some key electrochemical systems, both conventional and emerging. These papers discuss the latest issues associated with development, synthesis, characterization and use of new advanced carbonaceous materials for electrochemical energy storage. Such systems include: metal-air primary and rechargeable batteries, fuel cells, supercapacitors, cathodes and anodes of lithium-ion and lithium polymer rechargeable batteries, as well as nanocarbon materials of the future.

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New architecture in wood : forms and structures

Building with wood is currently enjoying a comeback. The reasons for the return of this ancient construction material are manifold. More than just being a renewable material that stores the carbon dioxide so damaging to the climate, it also has excellent structural properties, creates an ideal interior climate, and is easily combined with all other common building materials. The diverse applications can draw on expertise with wooden structures gained over centuries plus current research into modern timber engineering. Significant new developments in this specialist discipline have been seen in recent decades, especially in the German-speaking countries.

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New Approaches to Circle Packing in a Square : With Program Codes

This book summarizes results achieved in solving the circle packing problem over the past few years, providing the reader with a comprehensive view of both theoretical and computational achievements. Typically illustrations of problem solutions are shown, elegantly displaying the results obtained.Beyond the theoretically challenging character of the problem, the solution methods developed in the book also have many practical applications. Direct applications include cutting out congruent two-dimensional objects from an expensive material, or locating points within a square in such a way that the shortest distance between them is maximal.

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New advances in audio signal processing

In the era of digitalization, audio signal processing is gaining peculiar relevance as an automation and remote analysis means, also considering its enhancement by novel artificial intelligence (AI) techniques. This Reprint aims to offer an overview of the current developments in all fields that revolve around audio processing: from advancements in the acoustic domain to deep learning architectures for the audio-based analysis of real-world problems such as pitch detection or pathology identification.

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Neutrophil : Methods and Protocols

Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. This volume provides a concise set of protocols for assessing basic neutrophil functions and investigating specialized areas in neutrophil biology. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Part I contains overviews of neutrophil biology, function, and disorders. Part II describes commonly used methods to isolate neutrophils from humans and other animal species. Part III details methods for investigating chemotaxis, transmigration, phagocytosis, and bactericidal activity. Part IV includes protocols that measure neutrophil apoptosis, calcium signal transduction, degranulation and detection of cytoplasmic granules, gene expression, transcription factors, and apoptosis. Part V provides multiple assays for measuring production of intracellular and/or extracellular reactive oxygen species, and a method that details use of the cell-free NADPH oxidase assay, an iconic assay for studies of the neutrophil NADPH oxidase. Part VI provides chapters that describe how to analyze formation and function of neutrophil extracellular traps.

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Neutron and X-ray Spectroscopy

Neutron and X-Ray Spectroscopy delivers an up-to-date account of the principles and practice of inelastic and spectroscopic methods available at neutron and synchrotron sources, including recent developments. The chapters are based on a course of lectures and practicals (the HERCULES course) delivered to young scientists who require these methods in their professional careers. Each chapter, written by a leading specialist in the field, introduces the basic concepts of the technique and provides an overview of recent work. This volume, which focuses on spectroscopic techniques in synchrotron radiation and inelastic neutron scattering, will be a primary source of information for physicists, chemists and materials scientists who wish to acquire a basic understanding of these techniques and to discover the possibilities offered by them. Emphasizing the complementarity of the neutron and X-ray methods, this tutorial will also be invaluable to scientists already working in neighboring fields who seek to extend their knowledge.

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Neutrino Geophysics ; Proceedings of Neutrino Sciences 2005

This volume presents a collection of recent articles primarily documenting the nascent science of neutrino geophysics. Most of the articles followed from talks given at Neutrino Sciences 2005: Neutrino Geophysics held at the University of Hawaii in December 2005. However, several other key contributions were solicited to make the collection as comprehensive as possible, enhancing the value of this book.The book offers a unique status report on neutrino geophysics to the expert researcher, as well as a comprehensive introduction into this new field of science to graduate students.

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Neurosurgery : Principles and Practice

This book provides coverage of a broad range of topics in the ?eld of neurosurgery, 5 for residents and registrars in training and for recent graduates of training programs. 6 As neurosurgical training incorporates expertise from centers worldwide, there is a 7 need to have input from specialists in neurosurgery from various countries. This text 8 is a compilation by expert authors in the USA and the UK to provide information on 9 the basic knowledge and clinical management required for optimal care of neuro- 2011 surgical patients. 1 The text is an up-to-date synopsis of the ?eld of neurosurgery from American and 2 British perspectives, which covers the most common clinical conditions encountered 3 by neurosurgeons. The chapters are organized under broad topics, including inves- 4 tigative studies, perioperative care, the role of newer techniques and the management 5 of tumors, vascular and traumatic lesions. Additional topics are then covered, includ- 6 ing pediatrics, spine and peripheral nerve lesions, as well as functional neurosurgery 7 and infections. We anticipate that trainees will ?nd this information useful for certi?- 8 cation examinations and recent graduates of neurosurgical training programs can 9 utilize this text as an update of the most important neurosurgical topics.

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Neuroscribe = نيوروسكرايب

Neuroscribe is a cutting-edge deep learning framework designed to address the complexities and inefficiencies encountered in existing frameworks like PyTorch and TensorFlow. Aimed at streamlining model development and enhancing performance across diverse hardware environments, NeuroScribe offers a lightweight and flexible solution. The framework features a robust tensor library, an auto-differentiation engine, a comprehensive neural network module, and advanced optimization algorithms. With built-in visualization tools and a user-friendly interface, NeuroScribe simplifies both beginner and advanced workflows. Its cross-platform compatibility, supported by CUDA and Metal Performance Shaders (MPS), ensures optimal performance, and in some scenarios, NeuroScribe demonstrates superior speed compared to leading frameworks. Additionally, NeuroScribe introduces unique libraries and features not found in other frameworks, further enhancing its versatility and appeal. The modular architecture and automatic system detection further enhance its adaptability, making NeuroScribe a versatile and powerful tool for deep learning practitioners.

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Neuropsicologia della comunicazione = Neuropsychology of communication

Le più recenti acquisizioni della neuropsicologia cognitiva hanno consentito di focalizzare la natura dei processi linguistici e comunicativi, individuando i correlati fisiologici ed anatomici sottostanti alla produzione (encoding) e alla comprensione (decoding) del linguaggio. La prima parte del volume intende esplorare i paradigmi, i metodi e gli strumenti della neuropsicologia "per" la comunicazione. Nella seconda parte del contributo vengono prese in considerazione le componenti pragmatiche della comunicazione. Recenti modelli si sono occupati in particolare di alcuni fenomeni peculiari dello scambio comunicativo che mettono in rilievo il ruolo prioritario del "voler dire" nella comunicazione ordinaria (ironia, comunicazione idiomatica, metafora e, più in generale, linguaggio iconico o figurato). La terza parte del libro analizza il piano comunicativo non-verbale, con particolare attenzione alla comunicazione delle emozioni. Più specificamente vengono prese in considerazione le componenti mimiche e vocali nell’encoding e nel decoding delle emozioni. Questo volume, rivolto a neuropsicologi, psicologi, logopedisti e medici generici, potrà essere un utile strumento di lavoro anche per gli specializzandi di tali discipline.

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Neuronal cell death : Methods and protocols

Covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia using state-of-the-art microscopy techniques including super-resolution imaging, electron microscopy, and ultra-high field MRI. The chapters in this book cover topics such as analysis of neurodegeneration in the post-mortem characterization of preclinical animal models, in vivo modeling in cell death in different model systems and brain organoids, single cell clonal analysis using Mosaic Analysis with Double Markers in genetic mouse models, and genome and proteomic methods for analysis of mRNA dynamics and quantitation of targeted peptides.

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Neuromarketing e Processi Decisionali : Le evidenze di un test di memorizzazione condotto per la prima volta in Italia = Neuromarketing and decision-making processes: Evidence from a memory test conducted for the first time in Italy

Il libro fornisce alcuni strumenti scientifici per affrontare il problema di come il nostro cervello genera delle scelte in campo economico, in un linguaggio piano e non specialistico. Vengono descritti i risultati del primo studio italiano relativo all’osservazione di filmati commerciali televisivi, analizzati mediante l’elettroencefalografia ad alta risoluzione spaziale. La neuroeconomia è una nuova scienza che si sta sviluppando rapidamente nei paesi anglosassoni. Questo libro spiega i concetti di neuroeconomia e neuromarketing anche al pubblico italiano.

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Neuroimmune Pharmacology

This exciting new textbook, Neuroimmune Pharmacology, reflects the history and vision of the Society on NeuroImmune Pharmacology and of the Society’s official publication, the Journal of Neuroimmune Pharmacology. All three represent deliberations arising from a relatively young, interdisciplinary, and dynamic field of research, which have major translational implications for neurodegenerative, neuroinflammatory, neuropsychiatric diseases, and infections of the nervous system. They all demonstrate the synergistic value of integrating the parts: Neuroscience, Immunology, and Pharmacology. The extraordinary accomplishment of Neuroimmune Pharmacology is its comprehensive nature.

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