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Membrane Trafficking in Viral Replication
The ability of viruses to exploit cellular functions for their own ends makes them highly effective pathogens and exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. Each of the eight chapters in this volume deals with a specific aspect of viral interactions with cellular membranes. These include chapters on viral entry, viral membrane fusion, viral membrane protein synthesis and transport, viral replication, viral interactions with cytoskeletal systems and the nucleus, the trafficking of viral membrane proteins and viral perturbation of host cell protein trafficking. These chapters should provide both an overview of cellular membrane trafficking mechanisms and viral interactions with these systems, as well as reviews of the current state of each of the fields.
Medical data processing and analysis
Medical data can be defined as obtaining information from patients (such as signals, images, sounds, chemical components and their concentration, body temperature, respiratory rate, blood pressure, and different treatment measurements) to quantify the patient’s status and disease stage. Computer-aided diagnostic (CAD) systems use classical image processing, computer vision, machine learning, and deep learning methods for image analysis. Using image classification or segmentation algorithms, they find a region of interest (ROI) pointing to a specific location within the given image or an outcome of interest in the form of a label pointing to a diagnosis or prognosis. Computer science, with the evolution of artificial intelligence and machine learning techniques, facilitates the modeling and interpretation of results—from carrying out measurements to experiments and observations.
Mechanisms of Lymphocyte Activation and Immune Regulation X ; Innate Immunity
Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Mechanics of Biological Tissue
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.
Measuring the Value of Culture : Methods and Examples in Cultural Economics
Acknowledgement of the value of culture and cultural goods is increasing world-wide. So too is interest in finding methods to quantify this value so that governments and private sponsors can make efficient funding decisions. "Measuring the Value of Culture" documents methods that can be used to put a price on the arts and cultural goods, including theatre, heritage, cultural events (like arts festivals), museums, archaeological sites and libraries. The methods discussed include economic impact studies, which use market data, as well as non-market valuation techniques, like willingness to pay studies, and the newer choice experiments. In addition, advances in more qualitative valuation methods are considered.
Measurement Uncertainty : An Approach via the Mathematical Theory of Evidence
This text is the first to make full use of the mathematical theory of evidence to express the uncertainty in measurements. It gives an overview of the current standard, then pinpoints and constructively resolves its limitations through its unique approach. The text presents various tools for evaluating uncertainty, beginning with the probabilistic approach and concluding with the expression of uncertainty using random-fuzzy variables. The exposition is driven by numerous examples. The book is designed for immediate use and application in research and laboratory work.
Measurement Errors and Uncertainties : Theory and Practice
Measurement Errors and Uncertainties addresses the most important problems that physicists and engineers encounter when estimating errors and uncertainty. Building from the fundamentals of measurement theory, the author develops the theory of accuracy of measurements and offers a wealth of practical recommendations and examples of applications.
Matter and Methods at Low Temperatures
Matter and Methods at Low Temperatures contains a wealth of information essential for successful experiments at low temperatures, which makes it suitable as a reference and textbook. This third edition also describes newly developed low-temperature experimentation techniques and new materials properties; it also contains many additional references and a list of suppliers of cryogenic equipment.
Mathematical Models of Granular Matter
Granular matter displays a variety of peculiarities that distinguish it from other appearances studied in condensed matter physics and renders its overall mathematical modelling somewhat arduous. Prominent directions in the modelling granular flows are analyzed from various points of view. Foundational issues, numerical schemes and experimental results are discussed. The volume furnishes a rather complete overview of the current research trends in the mechanics of granular matter. Various chapters introduce the reader to different points of view and related techniques. New models describing granular bodies as complex bodies are presented. Results on the analysis of the inelastic Boltzmann equations are collected in different chapters. Gallavotti-Cohen symmetry is also discussed.
Isodual theory of antimatter : With applications to antigravity, grand unification and cosmology
Antimatter, already conjectured by A. Schuster in 1898, was actually predicted by P.A.M. Dirac in the late 19-twenties in the negative-energy solutions of the Dirac equation. Its existence was subsequently confirmed via the Wilson chamber and became an established part of theoretical physics. Dirac soon discovered that particles with negative energy do not behave in a physically conventional manner, and he therefore developed his "hole theory". This restricted the study of antimatter to the sole level of second quantization. As a result antimatter created a scientific imbalance, because matter was treated at all levels of study, while antimatter was treated only at the level of second quantization.In search of a new mathematics for the resolution of this imbalance the author conceived what we know today as Santilli’s isodual mathematics, which permitted the construction of isodual classical mechanics, isodual quantization and isodual quantum mechanics. The scope of this monograph is to show that our classical, quantum and cosmological knowledge of antimatter is at its beginning with much yet to be discovered, and that a commitment to antimatter by experimentalists will be invaluable to antimatter science.
Ionic Soft Matter : Modern Trends in Theory and Applications; Proceedings of the NATO Advanced Research Workshop on Ionic Soft Matter: Modern Trends in Theory and Application Lviv, Ukraine, 14-17 April, 2004
Consists of reviews of the experimental, theoretical and simulation studies on ionic criticality, polyelectrolytes, proton transport in fuel cell membranes, and the design of DNA arrays. This book deals with discussions of the fundamental and applied problems of important phenomena such as ion association, ion adsorption, ion solvation.
Inverse Problems for Partial Differential Equations
The topic of the inverse problems is of substantial and rapidly growing interest for many scientists and engineers. The second edition covers most important recent developments in the field of inverse problems, describing theoretical and computational methods, and emphasizing new ideas and techniques. It also reflects new changes since the first edition, including some corrections. This edition is considerably expanded, with some concepts such as pseudo-convexity, and proofs simplified. New material is added to reflect recent progress in theory of inverse problems.This book is intended for mathematicians working with partial differential equations and their applications, and physicists, geophysicists and engineers involved with experiments in nondestructive evaluation, seismic exploration, remote sensing and tomography.
Intumescent Coating and Fire Protection of Steel Structures
Introduced are the features and applications of intumescent coatings for protecting steel structures against fire. The constant effective thermal conductivity is defined and employed to simplify the quantification for the thermo-resistance of intumescent coatings. An experimental investigation into the hydrothermal aging effects on insulative properties of intumescent coatings is presented, as well as the influence of topcoat on insulation and aging of intumescent coatings. Also described is a practical method for calculating the temperature of the protected steel structures with intumescent coatings in order to evaluate the fire safety of a structure.
Introduction to Engineering Statistics and Six Sigma : Statistical Quality Control and Design of Experiments and Systems
Introduction to Engineering Statistics and Six Sigma contains precise descriptions of all of the many related methods and details case studies showing how they have been applied in engineering and business to achieve millions of dollars of savings. Specifically, the methods introduced include many kinds of design of experiments (DOE) and statistical process control (SPC) charting approaches, failure mode and effects analysis (FMEA), formal optimization, genetic algorithms, gauge reproducibility and repeatability (R&R), linear regression, neural nets, simulation, quality function deployment (QFD) and Taguchi methods. A major goal of the book is to help the reader to determine exactly which methods to apply in which situation and to predict how and when the methods might not be effective.
Introduction to Computational Biology : An Evolutionary Approach
Molecular biology has changed dramatically over the past two decades. Until the early 1990s genes were studied one at a time by small teams of researchers; today entire genomes are sequenced by internationally collaborating laboratories. In the bygone gene-centered era the accumulation of data was the rate-limiting step in research. Now that step is often data interpretation. This is increasingly dependent on computational methods and as a consequence, computational biology has emerged in the past decade as a new subdiscipline of biology. This introduction to computational biology is centered on the analysis of molecular sequence data. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes center stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors.
Introduction to basics of pharmacology and toxicology ; Vol.3 : Experimental pharmacology : Research methodology and biostatistics
Elaborates on the general principles of experimental pharmacology. Describes about the screening methods for the evaluation of different categories of drugs. Summarizes the various aspects of research methodology and biostatistics.
Introducing Molecular Electronics
This volume presents a summary of our current understanding of molecular electronics combined with selected state-of-the-art results at a level accessible to the advanced undergraduate or novice postgraduate. This single book comprises the basic knowledge of both theory and experiment underpinning this rapidly growing field. Concepts and techniques such as density functional theory and charge transport, break junctions and scanning probe microscopy are introduced step-by-step and are subsequently used in specific examples. The text addresses a wide range of systems including molecular junctions made of single-molecules, self-assembled monolayers, carbon nanotubes and DNA.
Intracranial Pressure and Brain Monitoring XII
88 short papers originating from the 12th International Symposium on Intracranial Pressure and Brain Monitoring held in August 2004 in Hong Kong present experimental as well as clinical research data on invasive and non-invasive intracranial pressure and brain biochemistry monitoring. The papers have undergone a peer-reviewing and are organized in nine sections: ICP management in head injury, neurochemical monitoring, intracranial hypertension, neuroimaging, hydrocephalus, clinical trails, experimental studies, brain compliance and biophysics.
Internal friction in metallic materials : A handbook
This book is a unique collection of experimental data in the field of internal friction, anelastic relaxation, and damping properties of metallic materials. It reviews virtually all anelastic relaxation phenomena ever published, and also most of the internal friction effects based on other types of dissipation of mechanical (elastic) energy. Furthermore, the reader is also supplied with explanations of the basic physical mechanisms of internal friction, a summary of typical effects for different groups of metals, and more than 2000 references to original papers.
Interior Spaces : Space, Light, Materials
Space, light and material: from the meditative ambiance of a chapel or synagogue to the colourful, organic forms of fashion boutiques, the design of an interior space - composed of lighting, the surfaces, textures and colours of materials, finishing and features - creates atmosphere and lends specific character. The growing willingness on the part of designers in recent years to experiment with colours, materials and spatial concepts is demonstrated in the range and diversity of international examples presented in this, the third volume in the series "In Detail". All plans and drawings of interiors and furnishings have been carefully researched and drawn by the staff of DETAIL.
