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Messung von Ressourceneffizienz mit der ESSENZ-Methode : Integrierte Methode zur ganzheitlichen Bewertung = Measuring resource efficiency with the ESSENCE method : Integrated method for holistic evaluation

Develops a reliable method for evaluating the use of resources. This is necessary because the strong economic growth of the last decades has led to an intensive use of natural resources. With their increasing use, there are also additional burdens on the environment and restrictions on the availability of resources. For these reasons, efficient use of resources is required as an important contribution to sustainable development.

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Messenger RNA therapeutics

Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.

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Meshless Methods in Solid Mechanics

The main objective of this book is to provide a textbook for graduate courses on the computational analysis of continuum and solid mechanics based on meshless (also known as mesh free) methods. It can also be used as a reference book for engineers and scientists who are exploring the physical world through computer simulations. Emphasis of this book is given to the understanding of the physical and mathematical characteristics of the procedures of computational solid mechanics. It naturally brings the essence, advantages and challenging problems of meshless methods into the picture. The subjects in this book cover the fundamentals of continuum mechanics, the integral formulation methods of continuum problems, the basic concepts of finite element methods, and the methodologies, formulations, procedures, and applications of various meshless methods. It also provides general and detailed procedures of meshless analysis on elastostatics, elastodynamics, non-local continuum mechanics and plasticity with a large number of numerical examples. Some basic and important mathematical methods are included in the Appendixes. For the readers who want to gain knowledge through hands-on experience, the meshless programs for elastostatics and elastodynamics are also introduced in the book and included in the disc.

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Meshfree Methods for Partial Differential Equations III

Meshfree methods for the numerical solution of partial differential equations are becoming more and more mainstream in many areas of applications. Their flexiblity and wide applicability are attracting engineers, scientists, and mathematicians to this very dynamic research area. This volume represents the state of the art in meshfree methods. It consists of articles which address the different meshfree techniques, their mathematical properties and their application in applied mathematics, physics and engineering.

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Meshfree Methods for Partial Differential Equations II

A Particle Strategy for Solving the Fokker-Planck Equation Modelling the Fiber Orientation Distribution in Steady Recirculating Flows Involving Short Fiber Suspensions.- Extended Meshfree Method for Elastic and Inelastic Media.- Meshfree Petrov-Galerkin Methods for the Incompressible Navier-Stokes Equations.- The ?-shape Based Natural Element Method in Solid and Fluid Mechanics.- A Particle-Partition of Unity Method Part VI: A p-robust Multilevel Solver.- Enriched Reproducing Kernel Approximation: Reproducing Functions with Discontinuous Derivatives.- Reproducing Kernel Element Interpolation: Globally Conforming I m/C n/P k Hierarchies.- Multi-scale Analysis Using Two Influence Radii in EFGM.- Solution of a Dynamic Main Crack Interaction with a System of Micro-Cracks by the Element Free Galerkin Method.- Finite Cover Method for Physically and Geometrically Nonlinear Problems.- A Numerical Scheme for Solving Incompressible and Low Mach Number Flows by the Finite Pointset Method.- SPH Renormalized Hybrid Methods for Conservation Laws: Applications to Free Surface Flows.- Discontinuous Radial Basis Function Approximations for Meshfree Methods.- Treating Moving Interfaces in Thermal Models with the C-NEM.- Bridging Scale Particle and Finite Element Methods.

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Mercury Pollution in Minamata

It overviews the poisoning which occurred in the 1950s and 1960s among the residents in Minamata who ate seafood contaminated with methylmercury discharged from the chemical factory, Chisso Corporation. It describes the history, symptoms pathogenesis and research on the causal agent, and discusses the responses of Chisso and the national and local governments to the outbreak, the victims, the compensation and environmental restructuring as well as the court ruling on claims. Based on lecture notes from a university course, it includes students’ suggestions for avoiding a repeat of the tragedy. The issue has not been settled yet, and this analysis of the incident provides useful insights into solutions to the current global mercury pollution problem.

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Mercury

Mercury, the planet closest to the Sun, is different in several respects from the other three terrestrial planets. In appearance, it resembles the heavily cratered surface of the Moon, but its density is high, it has a magnetic field and magnetosphere, but no atmosphere or ionosphere. This book reviews the progress made in Mercury studies since the flybys by Mariner 10 in 1974-75, based on the continued research using the Mariner 10 archive, on observations from Earth, and on increasingly realistic models of its interior evolution.

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Mente e Cuore : Clinica psicologica della malattia cardiaca = Mind and heart : Psychological Clinic of Heart Disease

Recent data has shown that there is a relationship between psychological conditions and heart disease. Furthermore, psychological interventions on patients with coronary heart disease (CHD) can reduce heart risk and improve their quality of life. This volume, which is the result of collaboration with the most committed international researchers in the field of clinical psychology and health applied to heart disease, presents an updated and complete overview of scientific research in this area. The first part of the volume presents the psychological pictures and relational aspects associated with heart disease with a particular focus on personality traits. The second part illustrates the psychological interventions in cardiac rehabilitation that research has shown to be effective in reducing cardiac risk. This text can be a useful reference to the practice of doctors, psychologists and health professionals who want to understand and deepen the link between heart disease and psychological aspects.

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Mental Health, Social Mirror

The essays in this volume reassert the centrality of research in mental health to sociology. First, they articulate the contributions that mental health research has made and can make to resolving key theoretical and empirical debates in important areas of sociological study. Second, they draw from mainstream theories and concepts to reconsider the potential of sociology to provide answers to critical questions regarding the social origins of and social responses to mental illness. As reflected in the title, the sociological study of mental health provides a reflection of the central processes that characterize our society.

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Menopause

As people live longer, women are spending most of their lives in menopause, affected by a variety of estrogen-related conditions such as osteoporosis, cognitive and cardiovascular decline, increased risk of breast cancer and other symptoms that decrease the overall quality of life. Unfortunately, hormonal therapy was found to be less effective in decreasing the severity of some of these conditions than previously thought and may actually increase the risk of cancer. The aim of this research was to put a spotlight on natural treatments for menopause like changing life style and herbal medicines.

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Men’s care center

"سين" مركزٌ للعافية والاسترخاء، مصمم بمزيج فريد من العناصر الطبيعية والهندسة المعمارية الحديثة ليمنح الزوار تجربة حسية متكاملة. يدمج المشروع المساحات الخضراء الداخلية والإضاءة الهادئة وخطوط التصميم المعاصرة لخلق بيئة فاخرة وهادئة. تشمل المساحات الرئيسية الحديقة الداخلية، والحمام التركي التقليدي، وغرف كبار الشخصيات، ومنطقة الاستقبال - جميعها مُرتبة بعناية لتعزيز الهدوء والتوازن. يركز التصميم على التفاصيل المعمارية والوظيفية، موفرًا للضيوف ملاذًا من ضغوط الحياة اليومية. خضعت التصاميم الداخلية والخارجية لدراسة دقيقة لضمان تجربة راقية وشاملة. “Sén” is a wellness and re laxation center designed with a unique blend of natural elements and modern architecture to provide visitors with a complete sensor experience. The project integrates indoor greenery, calming lighting, and con temporary design lines to create a luxurious and peaceful environment. Key spaces include the indoor garden, traditional hammam, VI P rooms, and reception area — all carefully arranged to promote tranquility and balance. The design focuses on architectural and functional details, offering guests a retreat from the stresses of everyday life. Both interior and exterior designs were carefully studied to ensure a refined and holistic experience.

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MEMS/NEMS : (1) Handbook Techniques and Applications Design Methods, (2) Fabrication Techniques, (3) Manufacturing Methods, (4) Sensors and Actuators, (5) Medical Applications and MOEMS

Micro-Electro Mechanical Systems (MEMS) is the integration of mechanical elements, sensors, actuators, and electronics on a common silicon substrate. While the electronics are fabricated using integrated circuit (IC) process sequences (e.g., CMOS, Bipolar, or BICMOS processes),the micromechanical components are fabricated using compatible micromachining processes that selectively etch away parts of the silicon wafer or add new structural layers to form the mechanical and electromechanical devices. MEMS promises to revolutionize nearly every product category by bringing together silicon-based microelectronics with micromachining technology, thereby, making possible the realization of complete systems-on-a-chip.

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Memories in Wireless Systems

This book is a guide which treats many components used in mobile communications, and in particular focuses on non-volatile memories. It emerges following the conducting line of the non-volatile memory in the wireless system: On the one hand it develops the foundations of the interdisciplinary issues needed for design analysis and testing of the system. On the other hand it deals with many of the problems appearing when the systems are realized in industrial production. These cover the difficulties from the mobile system to the different types of non-volatile memories.

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Mémento de la recherche biomédicale portant sur un médicament à usage humain = Summary of biomedical research on a medicinal product for human use

Presents the reference texts, structures and authorities that govern clinical research in France, as well as its practical aspects. It is aimed at all of its stakeholders, both caregivers and patients. It will allow the most novices to familiarize themselves with the specific vocabulary of this discipline, to answer the questions raised during the conduct or participation in a therapeutic trial, and the most experienced to consider setting up a research structure. clinic in the rules of art.

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Membrane Computing ; Vol. 4361 ; 7th International Workshop, WMC 2006, Leiden, Netherlands, July 17-21, 2006, Revised, Selected, and Invited Papers

The present volume contains a selection of papers presented at the Seventh Workshop on Membrane Computing, WMC7, which took place in Leiden, The Netherlands, during July 17–21, 2006. The ?rst three workshops on membrane computing were organized in Curtea de Arge¸ s, Romania – they took place in August 2000 (with the proceedings published in Lecture Notes in Computer Science, volume2235),in August 2001(with a selection of papers published asa special issue of Fundamenta Informaticae, volume 49, numbers 1–3, 2002), and in August 2002 (with the proceedings published in Lecture Notes in Computer Science, volume 2597). The next three workshops were organized in Tarragona, Spain, in July 2003, in Milan, Italy, in June 2004, and in Vienna, Austria, in July 2005, with the proceedings published as volumes 2933, 3365, and 3850, respectively, of Lecture Notes in Computer Science. The 2006edition of WMC wasorganized(and supported) byLorentzCenter, Leiden, under the auspices of the European Molecular Computing Consortium (EMCC). Special attention was paid to the interaction of membrane computing with biology, focusing both on the biological roots of membrane computing and on applications of membrane computing in biology and medicine.

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Membrane Computing ; Vol. 3850 ; 6th International Workshop, WMC 2005, Vienna, Austria, July 18-21, 2005, Revised Selected and Invited Papers

The papers in this volume cover all the main directions of research in membrane computing, ranging from theoretical topics in mathematics and computer science, to application issues, especially in biology. More specifically, these papers present research on topics such as: computational power and complexity classes, new types of P systems, relationships to Petri nets, quantum computing, and brane calculi, determinism vs. nondeterminism, hierarchies, the size of small families, algebraic approaches, and designing polynomial solutions to NP-complete problems through the use of membrane systems. Like the previous workshops,

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Melting Hadrons, Boiling Quarks - From Hagedorn Temperature to Ultra-Relativistic Heavy-Ion Collisions at CERN : With a Tribute to Rolf Hagedorn

Shows how the study of multi-hadron production phenomena in the years after the founding of CERN culminated in Hagedorn's pioneering idea of limiting temperature, leading on to the discovery of the quark-gluon plasma -- announced, in February 2000 at CERN.

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MEGAFLOW - Numerical Flow Simulation for Aircraft Design ; Results of the second phase of the German CFD initiative MEGAFLOW, presented during its closing symposium at DLR, Braunschweig, Germany, December 10 and 11, 2002

This volume contains results of the German CFD initiative MEGAFLOW which combines many of the CFD development activities from DLR, universities and aircraft industry. It highlights recent improvements and enhancements of the MEGAFLOW software system.

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Meeting Basic Learning Needs in the Informal Sector : Integrating Education and Training for Decent Work, Empowerment and Citizenship

This anthology brings together basic facts and features about basic learning needs and skills of people working and living in the informal economy and presents case studies from different countries examining educational and training strategies for meeting these learning needs. It portrays the grave problems facing educational and training systems vis-á-vis informal sector workers, even as they look at holistic solutions that take into account principles of lifelong learning and innovations in informal, non-formal and formal adult learning, and show a growing awareness that education is a human right of fundamental significance to promoting decent work and humane living conditions.

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Mediterranean Land-surface Processes Assessed from Space

1. 1 Space View and Ground Observations 1 1. 2 Mediterranean Climatic Environment 2 1. 3 Processes at Surfaces 10 1. 3. 1 Deforestation and Land-use Changes 10 1. 3. 2 Water Related Problems 16 1. 3. 3 Fire, Grazing, and Land Degradation 19 1. 3. 4 Drought, Floods, Frost, and Desertification 21 1. 3. 5 Coupling Between Surface and Atmosphere: The Role of the Atmospheric Boundary Layer 25 1. 4 Role and Capabilities of Measurements Made From Space 30 1. 4. 1 Research Programmes 30 1. 4. 2 Expected Information 32 1. 4. 3 Research Strategy 33 1. 4. 4 Observation of Changes in Heterogeneous Landscapes: Spatial and Temporal Scales 35 1. 4. 5 Land-surface Change Indicators Observable from Space 36 Spectral Characteristics of Vegetation and Soils (36); Responses of Remote Sensing Signals to Changes of Land-surface Properties (40) 1. 5 About this Book 48 Chapter 2 Processing and Archiving of Satellite and Ancillary Data 51 2. 1 Introduction 51 2. 2 The Remote Sensing Data Base 55 2. 2. 1 Satellite Instruments 55 The NOAA Observing System (55); Meteosat (57); Nimbus-7 (59); Landsat (59); SPOT (61); DMSP (62); ERS-1 and ERS-2 (62); TRMM (63); Terra (64); Envisat (65); Aqua (66) 2. 2. 2 Aircraft Instruments 66 The Use of Aircraft for Land-surface Process Studies (66); AVIRIS (67); TMS (68); AIRSAR (68); DIAL (69) 2. 3 Reception, Acquisition and Availability of Satellite Data 70 2. 3.

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