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Coastal dunes : Ecology and conservation
Brings together coastal dune specialists from tropical and temperate latitudes, which together cover a wide set of topics, including: geomorphology, community dynamics, ecophysiology, biotic interactions and environmental problems and conservation. A major product of this book is a set of recommendations for future research, identifying relevant topics where detailed knowledge is still lacking. It also identifies management tools that will promote and maintain the rich diversity of the dune environments in the context of continuing coastal development.
Co- and post-translational modifications of therapeutic antibodies and proteins
A Comprehensive Guide to Crucial Attributes of Therapeutic Proteins in Biological Pharmaceuticals With this book, Dr. Raju offers a valuable resource for professionals involved in research and development of biopharmaceutical and biosimilar drugs. This is a highly relevant work, as medical practitioners have increasingly turned to biopharmaceutical medicines in their search for safe and reliable treatments for
Clusia : A woody neotropical genus of remarkable plasticity and diversity
Clusia is the only dicotyledonous tree genus with crassulacean acid metabolism (CAM), and in some cases all variants of CAM can be expressed in one given species. These unique features as well as Clusia's extreme flexibility have put it in the limelight of international research. The studies presented in this volume embrace anatomy, morphology and plant architecture, phytogeographical distribution and community ecology, phylogeny and genetic diversity, physiology and metabolism, physiological ecology and functional diversity, circadian rhythmicity and biological timing. Covering all aspects of tree biology, this richly illustrated volume is an invaluable source of information for any plant scientist.
Cloud-Based Benchmarking of Medical Image Analysis
Presents the VISCERAL project benchmarks for analysis and retrieval of 3D medical images (CT and MRI) on a large scale, which used an innovative cloud-based evaluation approach where the image data were stored centrally on a cloud infrastructure and participants placed their programs in virtual machines on the cloud. The book presents the points of view of both the organizers of the VISCERAL benchmarks and the participants.
Clinicians guide to medical writing
Teaches what clinicians need to know about medical writing and publishing. It is for the physician, physician assistant, or nurse practitioner who sees patients and also wants to contribute to the medical literature, as well as for the assistant professor aspiring to promotion. It is written from the viewpoint of the clinician seeking the personal enrichment that writing can bring. Readers learn how to translate observations and ideas from practice into written form and eventually into print.
Clinical trial registries : A practical guide for sponsors and researchers of medicinal products
A necessary addition to the library of all researchers who plan to publish their results in top-tier, peer-reviewed journals. ICMJE editors and other journal editors require registration of clinical trial information on publicly available Web sites before enrollment of study subjects and some countries and regions also require this information, as well as timely publication of study results. Not only does this book discuss the genesis of these requirements, it also provides practical information for researchers and sponsors on how to establish a workflow for a clinical registry project, how to file to a registry, and how to post results. More than 25 current Web addresses for registries are provided as well as a comprehensive annotated bibliography of papers on the topic of clinical trial registries. This book is a valuable source of information for all sponsors of medicinal products.
Clinical text mining : Secondary use of electronic patient records
Describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records. It is divided into twelve chapters. Chapters 1-4 discuss the history and background of the original paper-based patient records, their purpose, and how they are written and structured. These initial chapters do not require any technical or medical background knowledge. The remaining eight chapters are more technical in nature and describe various medical classifications and terminologies such as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, and ATC. Chapters 5-10 cover basic tools for natural language processing and information retrieval, and how to apply them to clinical text. The book’s closing chapters present a number of applications in clinical text mining and summarise the lessons learned from the previous chapters.
Clinical pharmacy education, practice and research clinical pharmacy, drug information, pharmacovigilance, pharmacoeconomics and clinical research
Stresses educational approaches that empower pharmacists with patient care and research competencies. The learning objectives and writing style of the book focus on clarifying the concepts comprehensively for a pharmacist, from regular patient counseling to pharmacogenomics practice. It covers all interesting topics a pharmacist should know. This book serves as a basis to standardize and coordinate learning to practice, explaining basics and using self-learning strategies through online resources or other advanced texts. With an educational approach, it guides pharmacy students and pharmacists to learn quickly and apply. Clinical Pharmacy Education, Practice and Research provides an essential foundation for pharmacy students and pharmacists globally.
Clinical Pharmacology of Sleep
This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in children, adolescents, and in the elderly. It offers a comprehensive overview of the currently available hypnotic medications and covers aspects of chronopharmacology and its implications for the pharmacology of sleep. It also reviews the basic science of sleep and sleep disorders, and thus the potential development of new pharmacological approaches. The book will be useful for physicians, psychopharmacologists, psychiatrists, sleep disorder specialists and other healthcare professionals such as nurses, social workers and graduate medical students.
Clinical Pharmacology for Prescribing
Provides key points of basic pharmacology to explain drug actions / Shows clear relationship between pathophysiology and prescribing / Illustrations explain pharmacological mechanisms / Practical prescribing boxes highlight therapies for common conditions / 'Prescribing warnings' help readers to avoid adverse reactions and minimise side effects / Clear links to current medical guidelines throughout / Clear consistent structure in every chapter helps navigation and learning
Clinical PET and PET
A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed.
Mathematical Models for Registration and Applications to Medical Imaging
Image registration is an emerging topic in image processing with many applications in medical imaging, picture and movie processing. The classical problem of image registration is concerned with ?nding an appropriate transformation between two data sets. This fuzzy de?nition of registration requires a mathematical modeling and in particular a mathematical speci?cation of the terms appropriate transformations and correlation between data sets. Depending on the type of application, typically Euler, rigid, plastic, elastic deformations are considered. The variety of similarity p measures ranges from a simpleL distance between the pixel values of the data to mutual information or entropy distances. This goal of this book is to highlight by some experts in industry and medicine relevant and emerging image registration applications and to show new emerging mathematical technologies in these areas. Currently, many registration application are solved based on variational prin- ple requiring sophisticated analysis, such as calculus of variations and the theory of partial differential equations, to name but a few. Due to the numerical compl- ity of registration problems ef?cient numerical realization are required. Concepts like multi-level solver for partial differential equations, non-convex optimization, and so on play an important role. Mathematical and numerical issues in the area of registration are discussed by some of the experts in this volume.
Mathematical modeling of the human brain : From magnetic resonance images to finite element simulation
This book bridges common tools in medical imaging and neuroscience with the numerical solution of brain modelling PDEs. The connection between these areas is established through the use of two existing tools, FreeSurfer and FEniCS, and one novel tool, the SVM-Tk, developed for this book. The reader will learn the basics of magnetic resonance imaging and quickly proceed to generating their first FEniCS brain meshes from T1-weighted images.
Mathematical Modeling of Biological Systems ; Vol. I : Cellular Biophysics, Regulatory Networks, Development, Biomedicine, and Data Analysis
This two-volume, interdisciplinary work is a unified presentation of a broad range of state-of-the-art topics in the rapidly growing field of mathematical modeling in the biological sciences. Highlighted throughout both works are mathematical and computational approaches to examine central problems in the life sciences, ranging from the organizational principles of individual cells to the dynamics of large populations.
Materials science for dentistry
A standard resource for undergraduate and postgraduate courses in dentistry. It provides fundamental coverage of the materials on which dentistry depends, covering the structure and chemistry that govern the behavior and performance of materials. Particular classes of materials include gypsum, polymers, acrylic, cements, waxes, ceramics and metals. Other chapters review surfaces, corrosion, mixing, casting, cutting and bonding, and mechanical testing. This updated edition, which includes substantial chapters on chemistry, has been extensively revised with new material on temporary restoration resins, hydraulic silicate cements and the practical aspects of wetting surfaces. Mindfully written to provide explanations for behavior, formulation, clinical and laboratory instructions and procedures, there is no comparable resource for researchers, students, teachers and practitioners in the field of dentistry.
Materials for medical applications : Principles and practices
Discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications, especially in drug delivery, tumor screening, bioimaging, diagnosis, and therapies. Materials for Medical Applications provides comprehensive but concise information about materials and their medical applications. The readers will get information about the trends in materials and their medical applications, as well as current material-based products that are used in the medical field. The book also discusses how materials are tested in research laboratories, preclinical (animal) trials, and clinical (human) trials, and how material-based products go through various regulatory and safety phases before reaching patients. It also discusses topics such as materials delivery, imaging, and treatments for various diseases. It includes a chapter dedicated to regulatory guidelines and policies in the application of nanomaterials and will include current clinical trial information on the materials. Finally, the book has topics such as health safety, toxicity, dosages, and long-term implications of materials.
Material Modeling in Finite Element Analysis
Presents some specific problems including the metal-forming process, combustion room, Mullins effect of rubber tires, viscoelasticity of liver soft tissues, small punch test, tunnel excavation, slope stability, concrete slump test, orthodontic wire, and piezoelectric microaccelerometer.
Mastering Scientific And Medical Writing
Intended for scientific and medical professionals and students who wish to improve their scientific writing skills. This book contains exercises that invite the reader to practice important aspects of scientific writing.
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Martens and Fishers (Martes) in human-altered environments : An international perspective
Examines the conditions where humans and martens are compatible and incompatible, and promotes land use practices that allow Martes to be representatively distributed and viable. All Martes have been documented to use forested habitats and 6 species (excluding the stone marten) are generally considered to require complex mid- to late-successional forests throughout much of their geographic ranges. All species in the genus require complex horizontal and vertical structure to provide escape cover protection from predators, habitat for their prey, access to food resources, and protection from the elements. Martens and the fisher have high metabolic rates, have large spatial requirements, have high surface area to volume ratios for animals that often inhabit high latitudes, and often require among the largest home range areas per unit body weight of any group of mammals. Resulting from these unique life history characteristics, this genus is particularly sensitive to human influences on their habitats, including habitat loss, stand-scale simplification of forest structure via some forms of logging, and landscape-scale effects of habitat fragmentation. Given their strong associations with structural complexity in forests, martens and the fisher are often considered as useful barometers of forest health and have been used as ecological indicators, flagship, and umbrella species in different parts of the world. Thus, efforts to successfully conserve and manage martens and fishers are associated with the ecological fates of other forest dependent species and can greatly influence ecosystem integrity within forests that are increasingly shared among wildlife and humans.We have made great strides in our fundamental understanding of how animals with these unique life history traits perceive and utilize habitats, respond to habitat change, and how their populations function and perform under different forms of human management and mismanagement.
