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Immobilisation of DNA on Chips I
the main focus of these two volumes is on the immobilization chemistry, considering the various aspects of the immobilization process itself, since different types of nucleic acids, support materials, surface activation chemistries and patterning tools are of key concern.the focus of the major part of the chapters lies on the coupling chemistry used for DNA immobilization. Successful immobilization techniques for DNA appear to either involve a multi-site attachment of DNA (preferentially by electrochemical and/or physical adsorption) or a single-point attachment of DNA (mainly by surface activation and covalent immobilization or (strept)avidin-biotin linkage).
Imaging of Kidney Cancer
This is one of the first books to deal specifically with diagnostic imaging of the entire spectrum of kidney cancers. Both new and conventional imaging modalities are fully considered. In an introductory chapter, the histopathological classification of kidney cancers is presented and discussed. The following five chapters describe in great detail the abilities, advantages, and disadvantages of the various imaging modalities used in the diagnosis of kidney cancers and the assessment of disease extension. Subsequent chapters offer an exhaustive description of the radiological features of the different histological subtypes of kidney cancer, with radiological and histological illustrations and tables.
Image Analysis, Sediments and Paleoenvironments
This seventh volume of the DPER series examines imaging techniques for sedimentologists, paleolimnologists, paleoceanographers and microscopists working on issues related to paleoenvironmental reconstruction. It will help the researcher or graduate student to understand every step involved in the imaging process, from image acquisition to measurements.nbsp; Procedures are described to ensure that the right protocols and methodology are selected to solve a particular issue, and to evaluate the validity of scientific results. Case studies illustrate the wide range of information that can be obtained from many kinds of sediments (marine, lacustrine and aeolian) and different types of samples (cores, embedded blocks, microscopic slides) using different regions of the electromagnetic spectrum (visible, UV, IR, X-ray). The volume provides comprehensive protocols, guidelines, and recommendations for the use of low cost image analysis techniques, to facilitate intercomparisons of measurements.
Identifying, Assessing, and Treating Autism at School
As the rate of autism diagnosis continues to escalate, awareness and recognition of this developmental brain disorder - as well as a demand for services - are also mushrooming. School districts, already struggling under the weight of withering budgets and increasing enrollments, are now scrambling to strike a balance between the types of services and treatments parents want for their children and what the school system can afford to provide. Consequently, a broad cross-section of professionals and parents are searching for the means and methods by which to identify and address the wide-ranging.
Hypomelanosis Vitiligo & Albinism
• In General, understanding the disease is the best way to reach a perfect treatment. • This study aims to discuss the Hypomelanosis: • Vitiligo and Albinism and understanding the pathophysiology and present a types, symptoms and diagnosis of it. • Treatment ways and it's development, Nano-Drug and role of PRP in the treatments also had been presented. • The effect of Vitiligo on family members and living with it also had been discussed. • Finally, we have searched in managements and recommendations of Vitiligo patients during COVID-19 pandemic.
Human reliability and error in transportation systems
Each year billions of dollars are being spent to develop, manufacture, and operate transportation systems such as aircraft, ships, trains, and motor vehicles throughout the world. During their operation thousands of lives are lost annually due to various types accidents. Needless to say, approximately 70 to 90 percent of transportation crashes are the result of human error to a certain degree. Moreover, it may be added that human errors contribute significantly to most transportation crashes across all modes of transportation. Human Reliability and Error in Transportation Systems is the first book to cover the subject of human reliability across all types of transportation systems. The material will be accessible to readers with no previous knowledge in the field, and is supported with a full explanation of the necessary mathematical concepts together with numerous examples and test problems.
Human Cell Culture ; Vol. VI : Embryonic Stem Cells
If you wish to grow or characterize embryonic stem cells or persuade them to differentiate into a particular cell type, then this book contains information that is vital to your success. The aim is to provide clear simple instructions and protocols for growing, maintaining and characterizing embryonic stem cells and details of the various methods used to make stem cells differentiate into specific cell types.
Housing Estates in Europe : Poverty, Ethnic Segregation and Policy Challenges
Explores the formation and socio-spatial trajectories of large housing estates in Europe. Are these estates clustered or scattered? Which social groups originally had access to residential space in housing estates? What is the size, scale and geography of housing estates, their architectural and built environment composition, services and neighbourhood amenities, and metropolitan connectivity? How do housing estates contribute to the urban mosaic of neighborhoods by ethnic and socio-economic status? What types of policies and planning initiatives have been implemented in order to prevent the social downgrading of housing estates?The collection of chapters in this book addresses these questions from a new perspective previously unexplored in scholarly literature. The social aspects of housing estates are thoroughly investigated (including socio-demographic and economic characteristics of current and past inhabitants; ethnicity and segregation patterns; population dynamics; etc.), and the physical composition of housing estates is described in significant detail (including building materials; building form; architectural and landscape design; built environment characteristics; etc.).
Homotopy Methods in Topological Fixed and Periodic Points Theory
The notion of a fixed point plays a crucial role in numerous branches of mat- maticsand its applications. Informationabout the existence of such pointsis often the crucial argument in solving a problem. In particular, topological methods of fixed point theory have been an increasing focus of interest over the last century. These topological methods of fixed point theory are divided, roughly speaking, into two types. The ?rst type includes such as the Banach Contraction Principle where the assumptions on the space can be very mild but a small change of the map can remove the fixed point. The second type, on the other hand, such as the Brouwer and Lefschetz Fixed Point Theorems, give the existence of a fixed point not only for a given map but also for any its deformations. This book is an exposition of a part of the topological fixed and periodic point theory, of this second type, based on the notions of Lefschetz and Nielsen numbers. Since both notions are homotopyinvariants, the deformationis used as an essential method, and the assertions of theorems typically state the existence of fixed or periodic points for every map of the whole homotopy class, we refer to them as homotopy methods of the topological fixed and periodic point theory.
Hodgkins and Non-Hodgkins Lymphoma
In this volume, an internationally recognized group of experts provides a comprehensive overview of the biology, pathology, standard treatments, and novel approaches in management of patients across the complex landscape of lymphoma subtypes.
History of Science, History of Text
This book explores the hypothesis that the types of inscription or text used by a given community of practitioners are designed in the very same process as the one producing concepts and results. The book sets out to show how, in exactly the same way as for the other outcomes of scientific activity, all kinds of factors, cognitive as well as cultural, technological, social or institutional, conjoin in shaping the various types of writings and texts used by the practitioners of the sciences. To make this point, the book opts for a genuinely multicultural approach to the texts produced in the context of practices of knowledge
Highway engineering : Planning, design, and operations ; 2nd ed.
Presents a clear and rigorous exposition of highway engineering concepts, including project development and the relationship between planning, operations, safety and highway types. The book includes important topics such as corridor selection and traverses, horizontal and vertical alignment, design controls, basic roadway design, cross section elements, intersection and interchange design, and the integration of new vehicle technologies and trends. It also presents end of chapter exercises to further aid understanding and learning. This edition has been fully updated with the current design policies and reference manuals essential for highway, transportation, and civil engineers who are required to work to these standards.
Heterogeneous Objects Modelling and Applications : Collection of Papers on Foundations and Practice
Heterogeneous object modelling is a new and quickly developing research area. This book is one of the first attempts to systematically cover the most relevant themes and problems of this new and challenging subject area. It is a collection of invited papers and papers co-authored by the editors. Each chapter presents either new research results or a survey on the following topics:Formal models and abstractions of heterogeneous objects including geometric, topological, discrete and continuous models, operations forming special algebras and conversions between different model types.
Hepatitis C Virus Disease
Emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.
Hematologic Malignancies : Acute Leukemias
Several chapters in this volume describe current knowledge of acute leukemia biology and discuss new classification systems that have arisen consequent to emerging insights into pathogenesis. Treatment has also improved for particular types of acute leukemia.
Heart block
Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscle tissue, with the other two being skeletal muscle and smooth muscle. It is involuntary, striated muscle that constitutes the main tissue of the wall of the heart. The cardiac muscle (myocardium) forms a thick middle layer between the outer layer of the heart wall (the pericardium) and the inner layer (the endocardium), with blood supplied via the coronary circulation. It is composed of individual cardiac muscle cells joined together by intercalated discs, and encased by collagen fibers and other substances that form the extracellular matrix.
Has your House Got Cracks? : A Homeowner's Guide to Subsidence and Heave Damage
Provides practical guidance for homeowners whose properties have been affected by subsidence, or heave, or who are concerned by the potential risk of damage. The first, best-selling, edition dealt specifically with the problems associated with properties founded on shrinkable clay soils, and was reprinted many times. The second edition has been expanded to include sections on other types of subsidence and causes of damage that are unrelated to foundation movement.
Has Latin American Inequality Changed Direction? : Looking Over the Long Run
In this book, a group of global experts gathered by the Institute for the Integration of Latin America and the Caribbean (INTAL), part of the Inter-American Development Bank (IDB), show readers how various types of inequality, such as economical, educational, racial and gender inequality have been practiced in countries like Brazil, Bolivia, Chile, Mexico and many others through the centuries.
Hands-On Software Architecture with Java - Learn key architectural techniques and strategies to design efficient and elegant Java applications
Starts with the fundamentals of architecture and takes you through the basic components of application architecture. You'll cover the different types of software architectural patterns and application integration patterns and learn about their most widespread implementation in Java. You'll then explore cloud-native architectures and best practices for enhancing existing applications to better suit a cloud-enabled world. Later, the book highlights some cross-cutting concerns and the importance of monitoring and tracing for planning the evolution of the software, foreseeing predictable maintenance, and troubleshooting. The book concludes with an analysis of the current status of software architectures in Java programming and offers insights into transforming your architecture to reduce technical debt.
Hands-on question answering systems with BERT : Applications in neural networks and natural language processing
Begins with an overview of the technology landscape behind BERT. It takes you through the basics of NLP, including natural language understanding with tokenization, stemming, and lemmatization, and bag of words. Next, you’ll look at neural networks for NLP starting with its variants such as recurrent neural networks, encoders and decoders, bi-directional encoders and decoders, and transformer models. Along the way, you’ll cover word embedding and their types along with the basics of BERT. After this solid foundation, you’ll be ready to take a deep dive into BERT algorithms such as masked language models and next sentence prediction. You’ll see different BERT variations followed by a hands-on example of a question answering system. You will: Examine the fundamentals of word embeddings / Apply neural networks and BERT for various NLP tasks / Develop a question-answering system from scratch / Train question-answering systems for your own data
