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Neuroimmunology of Sleep

Neuroimmunology of Sleep provides an introduction to the interphase between sleep and neuroimmunology. Written both from basic and clinical perspectives, the volume contains useful information to many biomedical professionals and students of human biology.

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Neuroimmune Pharmacology

This exciting new textbook, Neuroimmune Pharmacology, reflects the history and vision of the Society on NeuroImmune Pharmacology and of the Society’s official publication, the Journal of Neuroimmune Pharmacology. All three represent deliberations arising from a relatively young, interdisciplinary, and dynamic field of research, which have major translational implications for neurodegenerative, neuroinflammatory, neuropsychiatric diseases, and infections of the nervous system. They all demonstrate the synergistic value of integrating the parts: Neuroscience, Immunology, and Pharmacology. The extraordinary accomplishment of Neuroimmune Pharmacology is its comprehensive nature.

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Neuroendocrine Correlates of Sleep/Wakefulness

This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology.

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Neuroendocrine cells and peptidergic innervation in human and rat prostrate

Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer.

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Neurodegeneration and Prion Disease

This volume provides an in-depth overview from world experts on prion disease. These fatal diseases include Creutzfeldt-Jakob disease, chronic wasting disease in deer, scrapie of sheep, bovine spongiform encephalopathy (mad cow’s disease) of cattle and related diseases. Understanding what causes neuronal death in these diseases is essential to both preventing and curing them. The most recent advances in understanding neuronal death in prion diseases are presented. Prion diseases serve as an experimental model for all neurodegenerative conditions. This book will provide understanding of neurodegeneration and provide an up-to-date record of the state of the art for other specialists and non-specialists in related fields.

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Neurochemical Aspects of Excitotoxicity

Leading researchers offer cutting-edge information on glutamate metabolism in the brain, examining the role of glutamate transporters and the involvement of glutamate receptors in the pathogenesis of acute neural trauma and neurodegenerative diseases.

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Neurobiology of Human Values

Man has been pondering for centuries over the basis of his own ethical and aesthetic values. Until recent times, such issues were primarily fed by the thinking of philosophers, moralists and theologists, or by the findings of historians or sociologists relating to universality or variations in these values within various populations. Science has avoided this field of investigation within the confines of philosophy. Beyond the temptation to stay away from the field of knowledge science may also have felt itself unconcerned by the study of human values for a simple heuristic reason, namely the lack of tools allowing objective study. For the same reason, researchers tended to avoid the study of feelings or consciousness until, over the past two decades, this became a focus of interest for many neuroscientists

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Neuroanatomy for the Neuroscientist

Neurology, more than any other system of medicine, is rooted in the firm knowledge of basic science material (i.e., the anatomy, physiology, and pathology of the nervous system). This material enables students to readily arrive at diagnoses and to apply their knowledge at solving problems in clinical situations. Neuroanatomy for the Neuroscientist gives neuroscientists the tools to teach this material at levels appropriate for students at several levels of study, including undergraduate, graduate, dental, and medical school. The text also provides an updated approach to lesion localization in neurology, utilizing the techniques of computerized axial tomography (CT scanning), magnetic resonance imaging (MRI), and magnetic resonance angiography (MRA). Multiple illustrations demonstrating the value of these techniques in clinical neurology and neuroanatomical localization has been provided.

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Neuroanatomical Tract-Tracing : Molecules, Neurons, and Systems

"The content of the book also serves to emphasize that neuroanatomy is, perhaps more than ever, a thriving and important part of the neurosciences...Most contributions have in common the combination of modern tract-tracing methods with other means of characterizing neural tissue, and thus the book also serves to highlight the gradual disappearance of borders between traditional neuroanatomy and other approaches to the study of the nervous system...this book should continue to be a useful source of information, and deserves to be available in all laboratories applying or considering to apply neuroanatomical methods."

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Neuroacanthocytosis Syndromes II

Awareness of neuroacanthocytosis disorders has increased significantly in recent years. There have been a number of important developments in the field since the publication of the first volume, Neuroacanthocytosis Syndromes. This book contains the latest research in this area. Recent advances have identified the range of mutations in the causative genes, shedding light on potential phenotype­genotype correlations. Studies of the proteins affected in these disorders have resulted in increased understanding of their functions and distribution. In vitro studies have identified potential protein interactions, which have important implications for pathophysiology. Work on erythrocyte membranes suggests mechanisms for the generation of acanthocytes. Animal models are being generated which will greatly facilitate understanding the role of gene mutations in humans, and provide the foundation for possible therapeutic interventions. In addition, advances in other neurodegenerative disorders, such as Huntington’s and Parkinson’s diseases, have implications for neuroacanthocytosis.

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Neuroacanthocytosis Syndromes

Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.

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Neural Networks : Methodology and Applications

Neural networks represent a powerful data processing technique that has reached maturity and broad application. When clearly understood and appropriately used, they are a mandatory component in the toolbox of any engineer who wants make the best use of the available data, in order to build models, make predictions, mine data, recognize shapes or signals, etc. Ranging from theoretical foundations to real-life applications, this book is intended to provide engineers and researchers with clear methodologies for taking advantage of neural networks in industrial, financial or banking applications, many instances of which are presented in the book. For the benefit of readers wishing to gain deeper knowledge of the topics, the book features appendices that provide theoretical details for greater insight, and algorithmic details for efficient programming and implementation. The chapters have been written by experts ands seemlessly edited to present a coherent and comprehensive, yet not redundant, practically-oriented introduction.

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Neural Crest Induction and Differentiation

Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.

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Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.

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Neonatal Immunity

New advances in cellular immunology, molecular biology, recombinant DNA and proteins, and the function of cytokines and chemokines have revolutionized the study of neonatal immune responsiveness. In Neonatal Immunity, Constantin Bona, MD, critically reviews the classic, as well as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens. Authoritative and forward-looking, Neonatal Immunity critically reviews what we know of the neonatal immune response today, and how this is dramatically opening new therapeutic horizons in such areas as infant vaccination, stem cells, gene therapy, and transplantation.

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Nectaries and Nectar

This book is a modern and interdisciplinary text on nectar and nectaries, prompted by the expansion of knowledge, especially in the more ecological and now molecular fields, and the strong recent interest in pollination biology.

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Natures Versatile Engine : Insect Flight Muscle Inside and Out

Integrates knowledge from various disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. This work features information on advances in muscle research, from the molecular to the organismal. It focuses on Drosophila melanogaster, and other species of flying insects are also covered.

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Nature, Value, Duty : Life on Earth with Holmes Rolston, III

"Nature Value and Duty: Life on Earth with Holmes Rolston, III" is a collection of contemporary writings on the work of Holmes Rolston, III. The authors contributing to this volume are a mixture of senior scholars in environmental ethics and new voices in philosophy and in literature. Together they provide an in depth evaluation of many of the topics discussed by Rolston. They probe the strengths and weaknesses of his work and suggest valuable correctives. Rolston himself, in a detailed reply to each of his critics at the end of the volume, reveals where some of these criticisms sting him the most and in the process provides one of the most detailed and articulate defenses of his position ever offered."

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Natural Resistance Mechanisms of Plants to Viruses

Resistance phenomena such as the local lesion response, induced resistance, "green islands" and resistance in various crop plants are linked with new information on gene-silencing mechanisms, gene silencing suppressors, movement proteins and plasmodesmatal gating, downstream signalling components, and more.

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Natural Oral Care in Dental Therapy

Because of increasing antibiotic resistance, stronger antibiotics are reserved for serious active infection, paving the way for a greater use of herbal antibiotics. This book helps dentists in implementing safe and effective natural medicine therapies to complement the current practice guidelines. Oral diseases continue to be a major health problem world-wide. Oral health is integral to general well-being and relates to the quality-of-life that extends beyond the functions of the craniofacial complex. The standard Western medicine has had only limited success in the prevention of periodontal disease and in the treatment of a variety of oral diseases.

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