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Artificial intelligence : The revolution of drug discovery

The successful application of AI is dependent on the availability of high-quality data, the addressing of ethical concerns, and the recognition of the limitations of AI-based approaches. Moreover artificial intelligence has been a game changer in the past decade. AI proved his worth by making the impossible possible in a short period of time. The health care industry has adopted artificial intelligence technology to deal with the ever-changing therapeutic and drug requirements of patients every day, as we encounter new viruses for which no antidote has been prepared, such as the Corona virus, diseases such as malaria, and the most important problem is the resistance to antibiotics by superbugs that are constantly developing new resistance mechanisms causing harm and confusion.

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Architect : The evolving story of a profession

From Ancient Egypt, where architects were members of the ruling class, tied into the running of the empire, to the 21st century when questions are being raised about the future of the profession, this book, with its engaging narrative, explores the constant threads that remain as the profession adapts. While architects are no longer deified, their ability to imagine a new impending reality in built form implies a visionary dimension to their work. By focusing on both the practicalities of the profession and the more intangible motivations behind design – humans’ need to make a mark upon their surroundings – this volume provides a critical overview of over 3000 years of practice and education.

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Applications of random matrices in physics

Random matrices are widely and successfully used in physics for almost 60-70 years, beginning with the works of Dyson and Wigner. Although it is an old subject, it is constantly developing into new areas of physics and mathematics. It constitutes now a part of the general culture of a theoretical physicist. Mathematical methods inspired by random matrix theory become more powerful, sophisticated and enjoy rapidly growing applications in physics. Recent examples include the calculation of universal correlations in the mesoscopic system, new applications in disordered and quantum chaotic systems, in combinatorial and growth models, as well as the recent breakthrough, due to the matrix models, in two dimensional gravity and string theory and the non-abelian gauge theories. The book consists of the lectures of the leading specialists and covers rather systematically many of these topics.

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Analytical Ultracentrifugation of Polymers and Nanoparticles

Analytical ultracentrifugation (AUC) is a powerful method for the characterization of polymers, biopolymers, polyelectrolytes, nanoparticles, dispersions, and other colloidal systems. The method is able to determine the molar mass, the particle size, the particle density and interaction parameters like virial coefficients and association constants. Because AUC is also a fractionation method, the determination of the molar mass distribution, the particle size distribution, and the particle density distribution is possible. A special technique, the density gradient method, allows fractionating heterogeneous samples according to their chemical nature that means being able to detect chemical heterogeneity.

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Analysis, Synthesis, and Perception of Musical Sounds : The Sound of Music

Analysis, Synthesis, and Perception of Musical Sounds contains a detailed treatment of basic methods for analysis and synthesis of musical sounds, including the phase vocoder method, the McAulay-Quatieri frequency-tracking method, the constant-Q transform, and methods for pitch tracking with several examples shown. Various aspects of musical sound spectra such as spectral envelope, spectral centroid, spectral flux, and spectral irregularity are defined and discussed. One chapter is devoted to the control and synthesis of spectral envelopes. Two advanced methods of analysis/synthesis are given: "Sines Plus Transients Plus Noise" and "Spectrotemporal Reassignment" are covered. Methods for timbre morphing are given. The last two chapters discuss the perception of musical sounds based on discrimination and multidimensional scaling timbre models.

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Anaesthesia, pain, intensive care and emergency medicine A.P.I.C.E. ; Proceedings of the 21st Postgraduate Course in Critical Medicine: Venice-Mestre, Italy - November 10-13, 2006

Developing sectors in the Intensive Care field – and in Critical Care Medicine in general – require specific levels of competence having a same common denominator: an in-depth knowledge of human pathophysiology. Although this volume presents plenty of topics in constant evolution, as witnessed by the collection of chapters compiled by several researchers, this edition includes, in particular, fields in which decision-making at the patient’s bedside prevails over theoretical argumentation. In other words, the first and foremost message this edition wants to provide is for the reader to focus his/her attention on evidence-based medicine.

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Agile processes in software engineering and extreme programming ; 17th International Conference, XP 2016, Edinburgh, UK, May 24-27, 2016, Proceedings

Contains the refereed proceedings of the 17th International Conference on Agile Software Development, XP 2016, held in Edinburgh, UK, in May 2016. While agile development has already become mainstream in industry, this field is still constantly evolving and continues to spur an enormous interest both in industry and academia. To this end, the XP conference attracts a large number of software practitioners and researchers, providing a rare opportunity for interaction between the two communities.

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Advances in proof-theoretic semantics

This volume is the first ever collection devoted to the field of proof-theoretic semantics. Contributions address topics including the systematics of introduction and elimination rules and proofs of normalization, the categorial characterization of deductions, the relation between Heyting's and Gentzen's approaches to meaning, knowability paradoxes, proof-theoretic foundations of set theory, Dummett's justification of logical laws, Kreisel's theory of constructions, paradoxical reasoning, and the defence of model theory.

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Advances in information system development : New methods and practice for the networked society ; Vol. 2

These volume on Information Systems Development examine the exchange of ideas between academia and industry and aims to explore new solutions. The field of Information Systems Development (ISD) progresses rapidly, continually creating new challenges for the professionals involved. New concepts, approaches and techniques of systems development emerge constantly in this field.

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A Generalization of Bohr-Mollerup's Theorem for Higher Order Convex Functions

This book develops a far-reaching generalization of Bohr-Mollerup's theorem to higher order convex functions, along lines initiated by Wolfgang Krull, Roger Webster, and some others but going considerably further than past work. In particular, this generalization shows using elementary techniques that a very rich spectrum of functions satisfy analogues of several classical properties of the gamma function, including Bohr-Mollerup's theorem itself, Euler's reflection formula, Gauss' multiplication theorem, Stirling's formula, and Weierstrass' canonical factorization.

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101 Ways to Save Money on Your Tax - Legally! 2022-2023

Tax laws are constantly changing, but you don’t have to pore over piles of legislation to file your tax accurately and completely — that’s what Mr. Taxman is here for. Don’t let yourself become one of the people who overpay. Find out what you actually owe, and prepare for even better savings next year. This guide removes the stress and confusion from tax season and helps you file on time with no mistakes. Whether you're an individual, married couple,

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