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Biomedical Informatics : Computer Applications in Health Care and Biomedicine
This series is directed to healthcare professionals who are leading the transformation of health care by using information and knowledge. Launched in 1988 as Computers in Health Care, the series offers a broad range of titles: some addressed to specific prof- sions such as nursing, medicine, and health administration; others to special areas of practice such as trauma and radiology.
Biomedical data mining for information retrieval : Methodologies, techniques, and applications
Discusses data mining, biomedical image processing, information retrieval with broad coverage of basic scientific applications. covers the topic of mining biomedical text, images and visual features towards information retrieval. Biomedical and health informatics is an emerging field of research at the intersection of information science, computer science, and healthcare and brings tremendous opportunities and challenges due to easily available and abundant biomedical data for further analysis. The aim of healthcare informatics is to ensure the high-quality, efficient healthcare, better treatment and quality of life by analyzing biomedical and healthcare data including patient’s data, electronic health records (EHRs) and lifestyle. Previously, it was a common requirement to have a domain expert to develop a model for biomedical or healthcare; however, recent advancements in representation learning algorithms allows us to automatically to develop the model. Biomedical image mining, a novel research area, due to the vast amount of available biomedical images, increasingly generates and stores digitally.
Biomarkers for alzheimer’s disease drug development
Aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Biological invaders in inland waters : Profiles, distribution, and threats
The book examines the identity, distribution, and impact of freshwater non-indigenous species and the dynamics of their invasion. Rather than providing a broad and comprehensive review of the issue, Biological invaders in inland waters focuses on old and new invaders and also raises questions and opens perspectives that provide a starting point for further research. The ultimate purpose of this book is to help define a more general framework for our knowledge of invasions in fresh waters. Such a framework will be indispensable to the planning of a science-based management program.
Biological adhesives
Many plants, animals, and microbes use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives. Emphasizing the diversity of biological adhesives and associated adhesion processes, it deals with bacteria, fungi, algae, and marine and terrestrial animals. It bridges a variety of disciplines including biochemistry, molecular biology, biomechanics, bioengineering, microbiology, organism structure and function, and ultrastructure. As we learn more about the molecular and mechanical properties of these adhesives, we begin to understand why they adhere so well and how they develop cohesive strength. With this understanding comes the prospect of developing synthetic or semi-synthetic adhesives with broad applications in areas such as medicine, dentistry, and biotechnology. The book is suitable for both industrial and academic researchers.
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Biogeography and Ecology of Bulgaria
The book includes 22 chapters by 28 authors united by the single theme: biogeography and ecology of Bulgaria. From the single-celled organisms in the Black Sea sand to the endemic cave crustaceans, from the mountain glacial relict insects to the most diverse bird fauna in Europe, the unique fauna of Bulgaria has been a subject of study of mostly Bulgarian zoologists for more than a century. This is the first monograph in English broadly addressing all vertebrate and many key invertebrate groups of Bulgaria, their faunistics, origin, geographical and ecological distribution, and conservation issues are addressed by the experts on each group.
Bio-Applications of Nanoparticles
In this edited book, we highlight the central players in the Bionanotechnology field, which are the nanostructures and biomolecules. The book starts by describing how nanostructures are synthesized and by describing the wide variety of nanostructures available for biological research and applications. Also shown are the techniques used to synthesize a wide variety of biological molecules. Next, there is a focus on the assembly of nanostructures with biological molecules, which could lead to the design of multi-functional nanosystems. In the following chapters, examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. Some applications include the use of gold nanoparticles in diagnostic applications, quantum dots and silica nanoparticles for imaging, and liposomes for drug delivery. In the final chapters of the book, the toxicity of nanostructures are described. This book provides broad examples of current developments in Bionanotechnology research and would be an excellent introduction to the field.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data and Global Trade Law
Explores the relevance of global trade law for data, big data and cross-border data flows. Contributing authors from different disciplines including law, economics and political science analyze developments at the World Trade Organization and in preferential trade venues by asking what future-oriented models for data governance are available and viable in the area of trade law and policy. The collection paints the broad picture of the interaction between digital technologies and trade regulation as well as provides in-depth analyses of critical to the data-driven economy issues, such as privacy and AI, and different countries' perspectives.
Big data analytics and machine intelligence in biomedical and health informatics : Concepts, methodologies, tools and applications
Provides coverage of developments and state-of-the-art methods in the broad and diversified data analytics field and applicable areas such as big data analytics, data mining, and machine intelligence in biomedical and health informatics. Covers the latest advances and developments in health informatics, data mining, machine learning, and artificial intelligence. They have been organized with respect to the similarity of topics addressed, ranging from issues pertaining to the Internet of Things (IoT) for biomedical engineering and health informatics, computational intelligence for medical data processing, and Internet of Medical Things??(IoMT).
Big Data : A Road Map for Successful Digital Marketing
Explores recent trends in the use of big data to predict consumer behavior, strategies to engage online customers, integration of big data with other data sources, and its applications in social media analytics, mobile marketing, search engine optimization and customer relationship management.
Beyond the limits to growth : New ideas for sustainability from Japan
This book offers an optimistic view of the future and provides a road map for societies to get there. Drawing upon extensive research and many years as a thought leader in environmental and sustainability issues in Japan and internationally, Hiroshi Komiyama analyzes the most pressing challenges to the attainment of sustainability of economically advanced nations and argues forcefully for Japan to lead them out of the present dilemma through active promotion of creative consumer and societal demand. He shows how an active industry–government–academic partnership can provide the environment needed to promote such new creative demand and illustrates its potential through presentation of a Platinum Society Network that was launched on a regional basis in Japan in 2010 to facilitate the solution of common issues through the exchange of information and ideas.
Beyond Cartesian Dualism : Encountering affect in the teaching and learning of science.
There is surprisingly little known about affect in science education. Despite periodic forays into monitoring students’ attitudes-toward-science, the effect of affect is too often overlooked. Beyond Cartesian Dualism gathers together contemporary theorizing in this axiomatic area. In fourteen chapters, senior scholars of international standing use their knowledge of the literature and empirical data to model the relationship between cognition and affect in science education. Their revealing discussions are grounded in a broad range of educational contexts including school classrooms, universities, science centres, travelling exhibits and refugee camps, and explore an array of far reaching questions. What is known about science teachers’ and students’ emotions? How do emotions mediate and moderate instruction? How might science education promote psychological
Between Peace and Conflict in the East and the West : Studies on Transformation and Development in the OSCE Region
This book features various studies on democratization, transformation, socio-economic development, and security issues in the Organization for Security and Cooperation in Europe (OSCE) geographical region and beyond. Written by experts and scholars working in the field of human dimension, security, transformation and development in Europe and Asia, particularly in post-soviet and communist countries, it examines the connectivity that the OSCE provides between the East and the West.
Between Necessity and Probability : Searching for the Definition and Origin of Life
This study investigates the major theories of the origins of life in light of modern research with the aim of distinguishing between the necessary and the optional and between deterministic and random influences in the emergence of what we call ‘life.’ Life is treated as a cosmic phenomenon whose emergence and driving force should be viewed independently from its Earth-bound natural history. The author synthesizes all the fundamental life-related developments in a comprehensive scenario, and makes the argument that understanding life in its broadest context requires a material-independent perspective that identifies its essential fingerprints.
Between Mobility and Migration : The Multi-Level Governance of Intra-European Movement
Offers a critical perspective on intra-European mobility and migration by using new empirical data and theoretical discussions. It develops a theoretical and empirical analysis of the consequences of intra-European movement for sending and receiving urban regions in The Netherlands, Sweden, Austria, Turkey, Poland and Czech Republic.The book conceptualizes Central and Eastern European (CEE) migration by distinguishing between different types of CEE migrants and consequences. This involves a mapping of migration corridors within Europe, a unique empirical analysis of consequences for urban regions, and an analysis of governance responses. Next to the European and country perspectives on this phenomenon, the book focuses on the local perspective of urban regions where most mobile citizens settle (either permanently or temporarily). This way the book puts the analysis of intra-European movement in the perspective of broader theoretical debates in migration studies and beyond.
Behavioral pharmacology of the cholinergic system
The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
Autonomy oriented computing : From problem solving to complex systems modeling
Autonomy Oriented Computing explores the important theoretical and practical issues in AOC, by analyzing methodologies and presenting experimental case studies. The book serves as a comprehensive reference source for researchers, scientists, engineers, and professionals in all fields concerned with this promising new development in computer science. It can also be used as a main or supplementary text in graduate and undergraduate programs across a broad range of computer-related disciplines, including Robotics and Automation, Amorphous Computing, Image Processing and Computer Vision, Programming Paradigms, Computational Biology, and many others. The first part of the book, Fundamentals, describes the basic concepts and characteristics of an AOC system, and then it enumerates the critical design and engineering issues faced in AOC system development. The second part of the book, AOC in Depth, provides a detailed analysis of methodologies and case studies to evaluate the use of AOC in problem solving and complex system modeling. The final chapter reviews the essential features of the AOC paradigm and outlines a number of possibilities for future research and development.
Autonomous Navigation in Dynamic Environments
The purpose of this book is to address the challenging problem of Autonomous Navigation in Dynamic Environments, and to present new ideas and approaches in this newly emerging technical domain. The book surveys the state-of-the-art, discusses in detail various related challenging technical aspects, and addresses upcoming technologies in this field. The aim of the book is to establish a foundation for a broad class of mobile robot mapping and navigation methodologies for indoor, outdoor, and exploratory missions.Three main topics located on the cutting edge of the state of the art are addressed, from both the theoretical and technological point of views: Dynamic world understanding and modelling for safe navigation, Obstacle avoidance and motion planning in dynamic environments, and Human-robot physical interactions. Several models and approaches are proposed for solving problems such as Simultaneous Localization and Mapping (SLAM) in dynamic environments, Mobile obstacle detection and tracking, World state estimation and motion prediction, Safe navigation in dynamic environments, Motion planning in dynamic environments, Robust decision making under uncertainty, and Human-Robot physical interactions.
