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Mechanisms of mineralization of vertebrate skeletal and dental tissues
Presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues.
Mechanisms of Angiogenesis
Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.
Mechanics of Structural Elements : Theory and Applications
The book systematically presents variational principles and methods of analysis for applied elasticity and structural mechanics. The variational approach is used consistently for both, constructing numerical procedures and deriving basic governing equations of applied mechanics of solids; it is the derivation of equations where this approach is most powerful and best grounded by mathematics. The book is oriented towards experts in civil engineering, researchers, developers of software for mechanical strength, stability, and oscillation analysis; it can be used by practical engineers who employ software tools to do their job and who want to know more about the theoretical background of the strength analysis. The book will be useful to senior and postgraduate students of engineering, to professors of structural analysis at civil or mechanical engineering departments of technical universities.
Mechanics of Microelectronics
Written by the leading experts with both profound knowledge and rich practical experience in advanced mechanics and microelectronics industry, this book aims to provide the cutting edge knowledge and solutions for various mechanical related problems, in a systematic way. It contains essential and detailed information about the state-of-the-art theories, methodologies, the way of working and real case studies.
Mechanics of Material Forces
The book covers both theoretical and numerical developments. Conceptually speaking, common continuum mechanics in the sense of Newton—which gives rise to the notion of spatial (mechanical) forces—considers the response to variations of spatial placements of "physical particles” with respect to the ambient space, whereas continuum mechanics in the sense of Eshelby—which gives rise to the notion of material (configurational) forces—is concerned with the response to variations of material placements of "physical particles” with respect to the ambient material. Well-known examples of material forces are driving forces on defects like the Peach-Koehler forece, the J-Integral in fracture mechanics, and energy release. The consideration of material forces goes back to the works of Eshelby, who investigated forces on defects; therefore this area of continuum mechanics is sometimes denoted Eshelbian mechanics.
Mechanics of biomaterials : Fundamental principles for implant design
Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues.
Mechanics of Biological Tissue
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.
Mechanics : From Newton's Laws to Deterministic Chaos
This updated and revised fourth edition covers all topics in mechanics from elementary Newtonian mechanics, canonical and rigid body mechanics to relativistic mechanics and nonlinear dynamics. In particular, symmetries and invariance principles, geometrical structures and continuum mechanics play an important role. This book will enable the reader to develop general principles from which equations of motions may be derived, to understand the importance of symmetries as a basis for quantum mechanics and to get practice in using theoretical tools and concepts that are essential for all branches of physics. The book contains numerous problems with complete solutions, and some practical examples.This will be appreciated in particular by students using the text to accompnay lectures on mechanics. The book ends with some historical remarks on important pioneers in mechanics.
Mechanical Ventilation
This book represents a state-of-the-art review by the leading experts in this field and covers a number of important topics including epidemiology, underlying physiological concepts, and approaches to monitoring. The pros and cons of various modes of ventilation are reviewed, as are novel forms of ventilation that may play a role in the future management of patients with respiratory failure. The importance of patient-ventilator synchrony and ventilator-induced lung injury are reviewed, with a focus on recent clinical trials and the challenges of implementing the results into clinical practice.
Mechanical Sytems, Classical Models ; Vol. I : Particle Mechanics
The guideline of the present book is precisely the mathematical model of mechanics. A special accent is put on the solving methodology as well as on the mathematical tools used; vectors, tensors and notions of field theory. Continuous and discontinuous phenomena, various mechanical magnitudes are presented in a unitary form by means of the theory of distributions.
Mechanical Response of Composites
This book contains twelve selected papers presented at the ECCOMAS Thematic Conference — Mechanical Response of Composites, and the papers presented by the three plenary speakers. It describes recent advances in the field of analysis models for the mechanical response of advanced composite materials, ranging from the simulation of the manufacturing process to the inelastic response and collapse of the material. The analysis models are based on recent advances in computational mechanics such as multi-scale modeling, cohesive and partition of unity models.
Mechanical Behaviour of Engineering Materials : Metals, Ceramics, Polymers, and Composites
How do engineering materials deform when bearing mechanical loads? To answer this crucial question, the book bridges the gap between continuum mechanics and materials science. The different kinds of material deformation (elasticity, plasticity, fracture, creep, fatigue) are explained in detail. The book also discusses the physical processes occurring during the deformation of all classes of engineering materials (metals, ceramics, polymers, and composites) and shows how these materials can be strengthened to meet the design requirements. It provides the knowledge needed in selecting the appropriate engineering material for a certain design problem. The reader will thus learn how to critically employ design rules and thus to avoid failure of mechanical components.
Mécanique céleste et contrôle des véhicules spatiaux = Celestial mechanics and spacecraft control
The textbook contains two parts: Part 1 is an introduction to celestial mechanics, and part II is devoted to the control of cosmic vehicles motion.The book is written in a clear mathematical style-Definition-Proposition-Lemma-Theorem-Corollary-and is almost self contained.
Meat Biotechnology
The main goal of this book is to provide the reader with the recent developments in biotechnology and their applications in the meat processing chain. To achieve this goal, the book is divided into four parts. The first part deals with the use of modern biotechnology applied to farm animals. The second part focuses on the recent biotechnological developments in starter cultures for better meat fermentation. The third part discusses current approaches to improve the quality and nutritional properties of meats. The final part presents the latest advances in protection against foodborne pathogens, and other recent trends in the field. Written by distinguished international contributors, this book brings together the advances in such varied and different biotechnological topics
Measuring the Value of Culture : Methods and Examples in Cultural Economics
Acknowledgement of the value of culture and cultural goods is increasing world-wide. So too is interest in finding methods to quantify this value so that governments and private sponsors can make efficient funding decisions. "Measuring the Value of Culture" documents methods that can be used to put a price on the arts and cultural goods, including theatre, heritage, cultural events (like arts festivals), museums, archaeological sites and libraries. The methods discussed include economic impact studies, which use market data, as well as non-market valuation techniques, like willingness to pay studies, and the newer choice experiments. In addition, advances in more qualitative valuation methods are considered.
Measuring Precipitation from Space : EURAINSAT and the Future
More than 20 years after the last book on the subject the worldwide precipitation community has produced a comprehensive overview of its activities, achievements, ongoing research and future plans. Measuring Precipitation from Space presents state-of-the-art rainfall estimation algorithms, validation strategies, precipitation modelling, and assimilation in numerical weather prediction models. Clouds and precipitation observations and modelling are addressed for the improvement of the rainfall product quality. Special attention is given to the applications to monitoring and forecasting weather events and to climate monitoring in a frame of growing public interest.
Measuring Methane Production from Ruminants
The world’s livestock sector is amidst a major transformation, fuelled by high demand for meat and milk, which is likely to double over the next two decades in developing countries. The challenge is to enhance animal productivity without adversely affecting the environment. A key to this is reducing methane emissions from ruminants. The major limitation to ruminant production in many tropical regions of Africa, Asia and Latin America, where a large proportion of the global ruminant population is located, is poor nutrition. The productivity of animals is restricted by the low nitrogen and high fibre content of the native grasses and crop residues, which form the basis of the diets in these regions. Animals on these types of diets emit more methane than animals fed better quality temperate forages. These methane emissions represent a loss of digestible energy to the animal (up to 15%) as well as a threat to the environment.The challenge is to devise nutritional strategies and identify dietary components, particularly from locally available plant resources, that reduce methane emissions.
Measuring human trafficking : Complexities and pitfalls
Measuring Human Trafficking needs to be read by scholars, professionals, and policymakers in the criminology and human rights fields. The ideas in this important volume can serve to improve the global knowledge base, strengthen coordination between agencies, and develop more effective solutions for combating this most pressing moral issue.
Measuring Globalisation : Gauging Its Consequences
Globalization a timely and controversial topic Presents comprehensive synthesis/overview of perspectives/approaches to "globalization", defines the term in more objective, scientific terms Presents rigorous empirical measures of globalization and its economic, political and social impact, w/implications for management and policy Authors represent different theoretical perspectives; are prolific and well-respected in the field
Measuring emission of agricultural greenhouse gases and developing mitigation options using nuclear and related Techniques : Applications of nuclear techniques for GHGs
This book is an outcome of the collaboration between the Soil and Water Management & Crop Nutrition Section, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna, Austria, and the German Science Foundation research unit DASIM (Denitrification in Agricultural Soils: Integrated control and Modelling at various scales) and other institutes.
