Page 4
Page 4
Co-design for System Acceleration : A Quantitative Approach
This book is concerned with studying the co-design methodology in general, and how to determine the more suitable interface mechanism in a co-design system in particular. Some new trends in co-design and system acceleration are also introduced.
Matematica e cultura 2005 = Mathematics and culture 2005
E si parla di arte; oltre che di Pizzinato, di Pollock, grazie alla collaborazione della Guggenheim Collection di Venezia.E si parla di architettura, dalla topologia ai progetti di Ghery e di Renzo Piano.E di modelli matematici per la lotta contro il cancro, contro l’AIDS.Di come la matematica può aiutare a prevenire e intervenire. E si parla di matematica della guerra e di come la matematica possa aiutare a proteggere l’ambiente. Nel gennaio 2005, scrivendo queste parole, diventa di grande e drammatica attualità l’utilizzo dei modelli matematici per la meteorologia. Prevedere per salvare.
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Marketing 5.0 : Technology for Humanity
Explains the greatest problem facing marketers today how to integrate three major movements that are changing global markets and customer behavior: Dramatic advances in technology such as AI, Sensors, and the Internet of Things, which are enabling extreme forms of customer targeting and personalization; Dramatic shifts in customer behavior, such as Whatever-Whenever-Wherever (WWW) and the differences between Generations X, Y, Z, and Alpha; And dramatic shifts in business models such as Everything as a Service, Physical/Digital business models.
Marine, Freshwater, and Wetlands Biodiversity
Marine, coastal and wetland habitats are threatened, not only through exploitation, but also by the prospect of climate change – as ocean currents change course, sea levels rise, and rainfall patterns change. Even the once-common cod is now under threat from the combined effects of over-fishing and a dramatic change-induced decrease in the plankton that cod larvae feed on. Meanwhile, coral reefs remain especially vulnerable to rapid sea-level changes exacerbated by the effects of tourism and disease. This book gathers together a wide range of papers reporting on key research into the biodiversity conservation of these critical and increasingly threatened habitats. Collectively these papers provide a snap-shot of the types of problems they are experiencing, and offer a wealth of topical examples which render this volume especially valuable to teachers of courses in marine, freshwater and wetlands ecology, biological conservation and ecological restoration.
Locational Tournaments in the Context of the EU Competitive Environment : A New Institutional Economics Approach to Foreign Direct Investment Policy Competition between Governments in Europe
The last decade has witnessed a dramatic change in attitude towards foreign direct investment (FDI) and a significant increase in competition between governments to attract FDI as a result. These "locational tournaments" are perpetuated not simply by classical factor endowments, but also by government interventions that impact both market imperfections and FDI flows.
Local Pattern Detection ; International Seminar Dagstuhl Castle, Germany, April 12-16, 2004, Revised Selected Papers
Introduction The dramatic increase in available computer storage capacity over the last 10 years has led to the creation of very large databases of scienti?c and commercial information. The need to analyze these masses of data has led to the evolution of the new field knowledge discovery in databases (KDD) at the intersection of machine learning, statistics and database technology. Being interdisciplinary by nature, the field offers the opportunity to combine the expertise of different fields into a common objective. Moreover, within each field diverse methods have been developed and justified with respect to different quality criteria. We have to investigate how these methods can contributet o solving the problem of KDD. Traditionally, KDD was seeking to end global models for the data that - plain most of the instances of the database and describe the general structure of the data. Examples are statistical time series models, cluster models, logic programs with high coverageor classi?cation models like decision trees or linear decision functions. In practice, though, the use of these models often is very l- ited, because global models tend to end only the obvious patterns in the data, 1 which domain experts already are aware of . What is really of interest to the users are the local patterns that deviate from the already-known background knowledge. David Hand, who organized a workshop in 2002, proposed the new field of local patterns.
Lasers, Clocks and Drag-Free Control : Exploration of Relativistic Gravity in Space
Over the next decade the gravitational physics community will benefit from dramatic improvements in many technologies critical to testing gravity. Highly accurate deep space navigation, interplanetary laser communication, interferometry and metrology, high precision frequency standards, precise pointing and attitude control, together with drag-free technologies, will revolutionize the field of experimental gravitational physics. The centennial of the general theory of relativity in 2015 will motivate a significant number of experiments designed to test this theory with unprecedented accuracy.
Korean modern : The matter of identity : An exploration into modern architecture in an east Asian country
The development of modern architecture in Korea and, more recently, South Korea, is closely tied to the country’s dramatic transformations since the late 19th century.The architectural analyses, ranging from Hwaseong Fortress to 21st-century constructions like Paju Book City, Ssamziegil Shopping Center, the Boutique Monaco skyscraper, and the Bauzium Sculpture Museum, focus on buildings in which the formation of a specifically Korean modernism is particularly observable. The appendix includes biographical descriptions of major architectural figures.
Changing the Game : The Playbook for Leading Business Transformation
As digital technologies and consumer expectations continue to disrupt almost every industry sector, companies are placing greater emphasis on developing and implementing transformation programs. Changing the Game offers the practical knowledge required to create a dramatic step-change in company performance. Adopting a robust and pragmatic approach to every stage of business transformation, this authoritative volume explains where to start, identifies key areas of focus, and describes the strategies, decisions, and actions necessary for achieving results.
Chance Rules : An informal guide to probability, risk and statistics
This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.
Cartographies of the Mind : Philosophy and Psychology in Intersection
The present book is a collection of essays exploring some classical dimensions of mind both from the perspective of an empirically-informed philosophy and from the point of view of a philosophically-informed psychology. In the last three decades, the level of interaction between philosophy and psychology has increased dramatically. As a contribution to this trend, this book explores some areas in which this interaction has been very productive – or, at least, highly provocative.
Cardiac reconstructions with allograft tissues
Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table.
Cancer vaccination and challenges Vol.2 : delivery strategies for cancer vaccine and immunotherapy in the management of various carcinomas
Covers delivery strategies of cancer vaccines for the management of various forms of carcinoma, examining the prospects of delivering immuno-oncology therapies, focusing specifically on effective drug delivery strategies for the treatment of lung, prostate, and pancreatic carcinomas.
Cancer vaccination and challenges Vol.1 : strategies for therapeutic cancer vaccine development
Deals with different strategies of cancer vaccine development, focusing on techniques for the development of therapeutic cancer vaccines and the roles of tumor antigens, proteins/peptides, microbial genes, and stem cells for the development of vaccines for cancer management.
Cancer
The last decade has seen a dramatic shift in anticancer drug research towards agents that aim to target selectively key regulatory and signaling processes known to drive tumorigenesis. A number of these newer agents have now been introduced into clinical practice. This volume reviews advances in cancer chemotherapy research over the last 10 years and will be of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy, growth factor inhibition, survival signaling, cell cycle inhibition, anti-angiogenics and anti-nvasives. Each chapter aims to cover the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
Biological Invasions in New Zealand
Man’s recent colonization of New Zealand has dramatically altered the resident biota and resulted in the introduction of numerous alien organisms to these once remote islands. In reverse, there is increasing evidence of a lesser known export of species to other regions of the world. This volume presents an in-depth review of the level and rate of such invasions, and investigates what controls the success of invaders and the consequences for ecosystems both on land and offshore. It provides invasion biologists everywhere with tests of current theories about those factors leading to the success of invaders as well as evaluating principles for understanding the nature of their impacts that form a solid basis for the effective management of biological invasions worldwide.
Belly-Rippers, surgical innovation and the ovariotomy controversy
This open access book looks at the dramatic history of ovariotomy, an operation to remove ovarian tumours first practiced in the early nineteenth century. Bold and daring, surgeons who performed it claimed to be initiating a new era of surgery by opening the abdomen. Ovariotomy soon occupied a complex position within medicine and society, as an operation which symbolised surgical progress, while also remaining at the boundaries of ethical acceptability. This book traces the operation’s innovation, from its roots in eighteenth-century pathology, through the denouncement of those who performed it as ‘belly-rippers’, to its rapid uptake in the 1880s, when ovariotomists were accused of over-operating. Throughout the century, the operation was never a hair’s breadth from controversy.
Arum palaestenium in cancer therapies
Cancer is a very complicated sequence of disease conditions progressing gradually with a generalized loss of growth control.1–3 There were only a few options of cancer treatment for patients for many decades which include surgery, radiation therapy, and chemotherapy as single treatments or in combination.4,5 But recently, many pathways involved in cancer therapy progression and how they can be targeted has improved dramatically, with combinatorial strategies, involving multiple targeted therapies or “traditional” chemotherapeutics, such as the taxanes and platinum compounds, being found to have a synergistic effect.6 New approaches, such as drugs, biological molecules, and immune-mediated therapies, are being used for treatment.
Architecture of computing systems - ARCS 2006 ; 19th International Conference, Frankfurt / Main, Germany, March 13-16, 2006, Proceedings
Technological progress is one of the driving forces behind the dramatic devel- mentofcomputersystemarchitecturesoverthe pastthreedecades.Eventhough it is quite clear that this development cannot only be measured by the ma- mum number of components on a chip, Moore’s Law may be and is often taken as a simple measure for the non-braked growth of computational power over the years. The more components are realizable on a chip, the more innovative and unconventional ideas can be realized by system architects. As a result, research in computer system architectures is more exciting than ever before. This book coversthe trends that shape the ?eld of computer system archit- tures.
