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High-Grade Gliomas : Diagnosis and Treatment
This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response.
Higher Education in Romania : Overcoming Challenges and Embracing Opportunities
The book focuses on areas of interest for Romanian higher education, such as systemic measures to improve access, participation and completion for (vulnerable) students, better promotion of the Romanian higher education to attract students, as well as instruments for a more efficient use of data at higher education level. Each article includes evidence-based policy proposals that could support new strategic initiatives in higher education, including new legislation.
Higher Education and Graduate Employment in Europe : Results from Graduates Surveys from Twelve Countries
The book indicates a noteworthy variety among economically advanced countries in the competences fostered by Higher Education and the emphasis placed either on laying a broad basis of knowledge or direct preparation for professional tasks. While universities in some countries are strongly involved in ensuring a rapid transition from study to employment, in other countries a long period after graduation is widespread for the search of a suitable career. Graduates from some countries appreciate their study experiences though they criticize a weak preparation for their subsequent assignments, while others less satisfied with higher education in their retrospective view note a satisfying preparation for the world of work. Study often turns out useful to lead to challenging tasks even though remuneration and status remain below expectations.
High Performance Computing for Geospatial Applications
This volume fills a research gap between the rapid development of High Performance Computing (HPC) approaches and their geospatial applications. With a focus on geospatial applications, the book discusses in detail how researchers apply HPC to tackle their geospatial problems. Based on this focus, the book identifies the opportunities and challenges revolving around geospatial applications of HPC. Readers are introduced to the fundamentals of HPC, and will learn how HPC methods are applied in various specific areas of geospatial study.
High performance computing and communications ; Vol. 4208 : 2nd International Conference, HPCC 2006, Munich, Germany, September 13-15, 2006, Proceedings
HPCC has moved into the mainstream of c- puting and has become a key technology in future research and development activities in many academic and industrial branches, especially when the so- tion of large and complex problems must cope with very tight time constraints. The HPCC 2006 conference provides a forum for engineers and scientists in academia, industry, and governmentto address all resulting profound challenges and to present and discuss their new ideas, research results, applications, and experience on all aspects of HPCC.
High mountain conservation in a changing world
This book aims to provide case studies and a general view of the main processes involved in the ecosystem shifts occurring in the high mountains, and to analyse the implications for nature conservation. Although case studies from the Pyrenees are preponderant, conclusions are aimed at any mountain range surrounded by highly populated lowland areas. The chapters give emphasis to approaches from environmental geography, functional ecology, biogeography, and paleoenvironmental reconstructions. The introductory and closing chapters summarize the main challenges that nature conservation may face in mountain areas under the environmental shifting conditions.
High Dielectric Constant Materials : VLSI MOSFET Applications
Issues relating to the high-K gate dielectric are among the greatest challenges for the evolving International Technology Roadmap for Semiconductors (ITRS). More than just an historical overview, this book will assess previous and present approaches related to scaling the gate dielectric and their impact, along with the creative directions and forthcoming challenges that will define the future of gate dielectric scaling technology. Topics include: an extensive review of Moore's Law, the classical regime for SiO2 gate dielectrics; the transition to silicon oxynitride gate dielectrics; the transition to high-K gate dielectrics (including the drive towards equivalent oxide thickness in the single-digit nanometer regime); and future directions and issues for ultimate technology generation scaling. The vision, wisdom, and experience of the team of authors will make this book a timely, relevant, and interesting, resource focusing on fundamentals of the 45 nm Technology Generation and beyond.
Heterogeneous Objects Modelling and Applications : Collection of Papers on Foundations and Practice
Heterogeneous object modelling is a new and quickly developing research area. This book is one of the first attempts to systematically cover the most relevant themes and problems of this new and challenging subject area. It is a collection of invited papers and papers co-authored by the editors. Each chapter presents either new research results or a survey on the following topics:Formal models and abstractions of heterogeneous objects including geometric, topological, discrete and continuous models, operations forming special algebras and conversions between different model types.
Heterogeneity, high performance computing, self-organization and the cloud
Addresses the most recent developments in cloud computing such as HPC in the Cloud, heterogeneous cloud, self-organising and self-management, and discusses the business implications of cloud computing adoption. Establishing the need for a new architecture for cloud computing, it discusses a novel cloud management and delivery architecture based on the principles of self-organisation and self-management. This focus shifts the deployment and optimisation effort from the consumer to the software stack running on the cloud infrastructure. It also outlines validation challenges and introduces a novel generalised extensible simulation framework to illustrate the effectiveness, performance and scalability of self-organising and self-managing delivery models on hyperscale cloud infrastructures. It concludes with a number of potential use cases for self-organising, self-managing clouds and the impact on those businesses.
Herbal pharmacopeia : Nanotechnology and advancing drug
Explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety assessments, novel and targeted delivery systems, and regulatory considerations, are thoroughly discussed. Additionally, it includes a comparative analysis of traditional and nano-formulated approaches and their implementation in clinical settings. Towards the end, the book reviews the regulatory considerations for herbal products and future perspectives in herbal pharmacopeia. This book is intended for researchers, clinicians, and professionals in herbal medicine, pharmacology, and nanotechnology.
Hedonic Methods in Housing Markets : Pricing Environmental Amenities and Segregation
Cities are growing worldwide and their sprawl is increasingly challenged for its pressure on open spaces and environmental quality. Economic arguments can help to decide about the trade-off between preserving environmental quality and developing housing and business surfaces, provided the benefits of environmental quality are adequately quantified. To this end, this book focuses on the use and advancement of the "hedonic approach", an economic valuation technique that analyses and quantifies the sources of rent and property price differentials. Starting from theoretical foundations, the hedonic approach is applied to the valuation of natural land use preservation and noise abatement measures, as well as to residential segregation and discrimination, extending the analysis to the role of the buyers' and sellers' identity on housing market prices and to the issue of environmental justice.
Healthcare solutions using machine learning and informatics
Covers novel and innovative solutions for the healthcare that apply machine learning and biomedical informatics technology. The healthcare sector is one of the most critical in society. This book presents a series of artificial intelligence, machine learning, intelligent IoT-based solutions for medical image analysis, medical big data processing, disease predictions. Machine learning and artificial intelligence use cases in healthcare presented in the book give researchers, practitioners, and students a wide range of practical examples of cross-domain convergence. The wide variety of topics covered include: Artificial Intelligence in healthcare Machine learning solutions for such disease as diabetes, arthritis, cardiovascular disease, and COVID-19 Big data analytics solutions for healthcare data processing Reliable biomedical applications using AI models Intelligent IoT in healthcare. The book explains fundamental concepts as well as the advanced use cases illustrating how to apply emerging technologies such as machine learning, AI models, data informatics into practice to tackle challenges in the field of healthcare with real-world scenarios. Chapters contributed by noted academicians and professionals examine various solutions, frameworks, applications, case studies, and best practices in the healthcare domain
Healthcare design basics
Delivers an up-to-date text covering the critical aspects of healthcare design, preparing students for a specialty rapidly growing in importance and size. includes: Step by step studio guidance outlining the basic design elements required for a wide range of ambulatory healthcare facilities and rooms Comprehensive explorations of the demands of new and improved healthcare facilities that meet the needs of an aging population Practical discussions of the space planning challenges involved in designing rooms and facilities for use during public health crises, including pandemics Dozens of full-color images that illustrate and highlight important concepts, examples, and design solutions
Health of People, Health of Planet and Our Responsibility : Climate Change, Air Pollution and Health
This book not only describes the challenges of climate disruption, but also presents solutions. The challenges described include air pollution, climate change, extreme weather, and related health impacts that range from heat stress, vector-borne diseases, food and water insecurity and chronic diseases to malnutrition and mental well-being.
Health and Modernity : The Role of Theory in Health Promotion
Health and Modernity proceeds from the thesis that contemporary health promotion is, by definition, inextricably linked to its social context. The authors discuss global challenges in terms of cultural capital, risk and causality, systems theory, and the dynamic between individual and community.
Harvesting Operations in the Tropics
The book brings together information on harvest methods, system productivity, and methods for conducting safe, efficient, and environmentally acceptable operations in tropical forests. It highlights the challenges of harvest operations in the tropics, includes techniques that have been shown to be successful, and discusses newer technologies.
Happiness is the Wrong Metric : A Liberal Communitarian Response to Populism
This timely book addresses the conflict between globalism and nationalism. It provides a liberal communitarian response to the rise of populism occurring in many democracies. The book highlights the role of communities next to that of the state and the market. It spells out the policy implications of liberal communitarianism for privacy, freedom of the press, and much else. In a ersuasive argument that speaks to politics today from Europe to the United States to Australia, the author offers a compelling vision of hope. Above all, the book offers a framework for dealing with moral challenges people face as they seek happiness but also to live up to their responsibilities to others and the common good.
Handbook Utility Management
As the deregulation of European utility markets has progressed, the dynamics of and the competitive pressure in the utility industries have steadily intensified over recent years. These changes in the regulatory framework have caused a shift in the direction of an integrated market environment, resulting in new challenges for the management of power and gas companies and a substantial need for strategic reorientation. The Handbook Utility Management is concerned with these changes and challenges in the utility industries and emerging managerial issues of high practical relevance. Inclusion of the latest insights into the economic, technological, and legal drivers of the diverse value chain activities makes the Handbook a valuable asset for both professionals and researchers.
Handbook on Information Technology in Finance
This Handbook contains surveys of state-of-the-art concepts, systems, applications, best practices as well as contemporary research in the intersection between IT and finance. Included are recent trends and challenges, IT systems and architectures in finance, essential developments and case studies on management information systems, service oriented architecture modelling, IT architectures for securities trading, IT-systems in banking, process-oriented systems in corporate treasuries, grid computing and networking. The IT applications in banking, trading and insurance cover risk management and controlling, financial portals, electronic payment and others. In addition, also finance-related IT applications in non-financial companies are considered. The concept-oriented part of the book focuses on IT methods in finance like financial models and modelling financial data, planning and processes, security, algorithms and complexity.
Handbook of urban health : Populations, methods, and practice
As more people worldwide live in cities, increasingly we need to understand how cities and city living affect population health. Does city living negatively affect health? Conversely, can city living enhance population health and well-being? Over forty experts from around the world bring a depth of ideas to the Handbook of Urban Health, making the Handbook a focused resource for a range of health disciplines. A unique professional idea book, research resource, and teaching text, the Handbook of Urban Health challenges readers to consider the role that cities plays in shaping population health and to generate solutions that can make cities healthier places for all those who live there.
