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Cancer immunotherapy : Methods and protocols

Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Calixarenes in the Nanoworld

Calixarenes have been widely exploited in all areas of supramolecular chemistry over the past three decades and many recent developments have concerned their applications in the production of chemical entities with the dimensions of nanometres, as in "nanochemistry".Calixarenes in the Nanoworld Relates calixarenes to nanochemistry – key information for industries engaged in the production of high-tech materials. Provides a timely review of both what is known and the exciting prospects provided by calixarenes, Contains several review articles which define the importance of calixarenes as reagents in nanochemistry.

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CADD and informatics in drug discovery

Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .

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Business process management Workshops ; Vol. 4103 : BPM 2006 International Workshops, BPD, BPI, ENEI, GPWW, DPM, semantics4ws, Vienna, Austria, September 4-7, 2006, Proceedings

BPM 2006 was the fourth in a conference series that provides a forum for - searchers and practitioners in all areas of business process management. In c- junction with BPM 2006, a series of workshops were held. They were meant to facilitate the exchange of ideas and experiences between active researchers, and to stimulate discussions on new and emerging topics in line with the conference topics. We see the workshops as a necessary extension to the main conference. BPM has established itself rapidly as a high quality conference with a highly competitive selection process.

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Business modeling and software design ; 10th International Symposium, BMSD 2020, Berlin, Germany, July 6-8, 2020, Proceedings

This book constitutes the refereed proceedings of the 10th International Symposium on Business Modeling and Software Design, BMSD 2020, which took place in Berlin, Germany, in July 2020. BMSD is a leading international forum that brings together researchers and practitioners interested in business modeling and its relation to software design. Particular areas of interest are: Business Processes and Enterprise Engineering; Business Models and Requirements; Business Models and Services; Business Models and Software; Information Systems Architectures and Paradigms; Data Aspects in Business Modeling and Software Development; Blockchain-Based Business Models and Information Systems; IoT and Implications for Enterprise Information Systems.

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Building to suit the climate : A handbook

Serves as a concrete aid to planning and design. With the planning process as its roadmap, it accompanies the planner from the basic evaluation stage through conception and implementation planning all the way to building operation. The building-related characteristics of the various climatic zones form the basis for the made-to-measure development of integrated building solutions. Well-conceived graphics illustrate planning contexts and facilitate efficient planning decisions and realistic predimensioning. Materials, systems, and technologies are described, and their areas of application are pointed out. Reference parameters, costs, and the presentation of interrelationships equip the planner to make a strategic and well-informed selection.

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Building codes illustrated : A guide to understanding the 2018 International Building Code ; 6th ed.

Provides brand new chapters on plumbing fixture counts, elevators, special construction, and existing buildings while updating the remainder of the material to align with recent changes to the IBC. includes: Thorough introductions to navigating the Code, use and occupancy, special uses and occupancies, and building heights and areas / Full explorations of the types of construction, fire resistive construction, interior finishes, fire-protection systems, and means of egress / Practical discussions of accessibility, interior environment, exterior walls, roof assemblies, and structural provisions / In-depth examinations of special inspections and tests, soils and foundations, building materials and systems, and elevators

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Brodmann's : Localisation in the Cerebral Cortex

It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.

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Brands and Consumers : A Research Overview

This short-form book provides a comprehensive overview of research evidence on several core branding topics whilst acting as a catalyst for advancing future research and informing business practice. The book represents a timely compendium on popular topics in branding and aims to be a valuable addition to knowledge in branding. The book focuses on reviewing research in branding and brand management, and proposes areas for expanding research in the field.

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Brain and Human Body Modeling : Computational Human Modeling at EMBC 2018

This book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner.

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Braid Groups

Braids and braid groups have been at the heart of mathematical development over the last two decades. Braids play an important role in diverse areas of mathematics and theoretical physics. The special beauty of the theory of braids stems from their attractive geometric nature and their close relations to other fundamental geometric objects, such as knots, links, mapping class groups of surfaces, and configuration spaces. In this presentation the authors thoroughly examine various aspects of the theory of braids, starting from basic definitions and then moving to more recent results. The advanced topics cover the Burau and the Lawrence--Krammer--Bigelow representations of the braid groups, the Alexander--Conway and Jones link polynomials, connections with the representation theory of the Iwahori--Hecke algebras, and the Garside structure and orderability of the braid groups.

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Botulinum toxin

Offering a step-by-step, practical approach to this commonly performed cosmetic procedure, Procedures in Cosmetic Dermatology: Botulinum Toxin, 5th Edition, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. It covers the science behind these neuromodulators and their usage areas in cosmetic dermatology, as well as the latest treatment options—all abundantly illustrated and evidence based. A substantial video library demonstrating injection techniques helps you successfully incorporate the latest procedures into your practice.

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Boosting Collaborative Networks 4.0 ; 21st IFIP WG 5.5 Working Conference on Virtual Enterprises, PRO-VE 2020, Valencia, Spain, November 23–25, 2020, Proceedings

This book constitutes the refereed proceedings of the 21st IFIP WG 5.5 Working Conference on Virtual Enterprises, PRO-VE 2020, held in Valencia, Spain, in November 2020. The conference was held virtually. The 53 full papers were carefully reviewed and selected from 135 submissions. They provide a comprehensive overview of major challenges and recent advances in various domains related to the digital transformation and collaborative networks and their applications with a strong focus on the following areas related to the main theme of the conference: collaborative business ecosystems; collaborative business models; collaboration platform; data and knowledge services; blockchain and knowledge graphs; maintenance, compliance and liability; digital transformation; skills for organizations of the future

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Biotechnology for Fuels and Chemicals : The Twenty-Ninth Symposium

In Biotechnology for Fuels and Chemicals: The Twenty-Ninth Symposium, leading US and international researchers from academia, industry, and government exchange cutting-edge technical information and update current trends in the development and application of biotechnology for sustainable production of fuels and chemicals. This symposium emphasizes advances in biotechnology to produce high-volume, low-price products from renewable resources, while improving the environment. The major areas of interest include advanced feedstock production and processing, enzymatic and microbial biocatalysis, bioprocess research and development, opportunities in biorefineries, and commercialization of biobased products. International and domestic progress on producing liquid biofuels, especially ethanol and biodiesel, is highlighted, and related topics, including bioseparations and optimal integration of biochemical and thermochemical conversion technologies, are featured.

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Biotechnology for fuels and chemicals : The Twenty-Eighth symposium

In Biotechnology for Fuels and Chemicals: The Twenty-Eighth Symposium, leading US and international researchers from academia, industry, and government exchange cutting-edge technical information and update current trends in the development and application of biotechnology for sustainable production of fuels and chemicals. This symposium emphasizes advances in biotechnology to produce high-volume, low-price products from renewable resources, while improving the environment. The major areas of interest include advanced feedstock production and processing, enzymatic and microbial biocatalysis, bioprocess research and development, opportunities in biorefineries, and commercialization of biobased products.

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Biosolids engineering and management

Biosolids Engineering and Management, is a collection of methods of practical design, calculation and numerical examples that illustrate how organized, analytical reasoning can lead to the discovery of clear, direct solutions, especially in the areas of biosolids management, treatment, disposal and beneficial use. The book’s including sludge and biosolids transport, pumping and storage, sludge conversion to biosolids, chlorination, stabilization, regulatory requirements, costs, agricultural land application, landfill, ocean disposal, combustion, incineration and sludge treatment process selection.

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Biosaline Agriculture and High Salinity Tolerance

this book reviews the current state of knowledge in biosaline agriculture and high salinity tolerance in plants. It mainly focuses on the biotic approach to economically utilize the stress-prone areas by growing resistant plants.This volume comprises three sections: physiology and biochemistry, ecology, and molecular biology. Thus, a systematic approach has been adopted to uncover plant responses to various ecological factors at physiological and molecular levels.

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Biophotonics ; Optical science and engineering for the 21st century

 Biophotonics: Optical Science and Engineering in the 21st Century serves as an ideal aid to the research and development of these areas integrating light, photonics, and biological systems.Key topics include: Fluctuation Correlation Spectroscopy in Cells: Determination of Molecular Aggregation ,Using GFP and FRET Technologies for Studying Signaling Mechanisms of Apoptosis in a Single Living Cell, Study on Protein-Protein Interaction in Single Living Cells, Functional Optical Coherence Tomography: Simultaneous In Vivo Imaging of Tissue Structure and Physiology, Imaging –Photo- and Sonodynamic Diagnosis of Cancer Mediated by Chemiluminescence Probes, Biophotonic Analysis of Spontaneous Self-Organizing Oxidative Processes in Aqueous Systems, Biophoton Emission and Defense Systems in Plants

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Biopharmaceutics applications in drug development

This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.

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BioMEMS and Biomedical Nanotechnology : Vol. I: Biological and Biomedical Nanotechnology

Abe Lee has been working on micro/ and nanotechnology for biomedical and biotech applications since 1992. His recent research focuses on the development of integrated micro and nano fluidic chip processors for the following applications: point-of-care diagnostics, "smart" nanomedicine for early detection and treatment, stem cell biology and therapeutics, the synthesis of novel and pure materials, and biosensors to detect environmental and terrorism threats. Jim Lee's research interest includes BioMEMS/NEMS, and polymer micro/nanotechnology. In the last 4 years, he has over 20 refereed journal publications, 2 book chapters, and 5 patents in these areas. He is now leading an NSF Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymer Biomedical Devices at OSU.

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