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Antibody-drug conjugates and cellular metabolic dynamics
Summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs.
Antibiotics : Methods and protocols
Provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols, Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Antibiotic users behavior in Syria between pharmacists and consumers
In an attempt to study antibiotic resistance in the syria, we studied the impact of consumer behavior On resistance. We conducted a study of pharmacists within a number(69) distributed in Damascus, and a study among consumers distributed among different regions, and the results are in the studies section.
Antibiotic prescribing pattern for patients with community-acquired pneumonia in Syrian hospitals
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.Antibiotics are essential for CAP treatment, whereas inappropriate use of antibiotics might lead to increase in resistant bacteria and treatment failure
Antibiotic Policies : Fighting Resistance
This book addresses many of the key issues taxing our society and hospitals in an era of epidemic resistance and shortage of new antibiotics. Written by internationally renowned experts in the field, this volume will provide practical advice and inform control strategies for the most urgent of problems related to antibiotic resistance epidemic for years to come. Antibiotic Policies: Fighting Resistance is an ideal volume for health professionals with an interest in this field.
Antibiotic Drug Resistance
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases.
Anthropologies of Global Maternal and Reproductive Health : From Policy Spaces to Sites of Practice
This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors – both internationally respected anthropologists and new voices – demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals’ and lay people’s intimate encounters with policy.
Anthracycline Chemistry and Biology II : Mode of Action, Clinical Aspects and New Drugs
This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.
Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry
"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."
Anterior knee pain and patellar instability
This multidisciplinary book reviews the diagnosis and management of anterior knee pain and patellar instability in an eminently clinical and practical manner. The book reviews the therapeutic alternatives, both surgical and non-surgical, emphasizing the considerable importance of minimal intervention and non-surgical methods. Similarly, anterior knee pain following ACL reconstruction is covered in detail.
Antennas & propagation for wireless communication systems ; 2nd ed.
Antennas and propagation are of fundamental importance to the coverage, capacity and quality of all wireless communication systems. This book provides a solid grounding in antennas and propagation, covering terrestrial and satellite radio systems in both mobile and fixed contexts. Building on the highly successful first edition, this fully updated text features significant new material and brand new exercises and supplementary materials to support course tutors. A vital source of information for practising and aspiring wireless communication engineers as well as for students at postgraduate and senior undergraduate levels, this book provides a fundamental grounding in the principles of antennas and propagation without excessive recourse to mathematics. It also equips the reader with practical prediction techniques for the design and analysis of a very wide range of common wireless communication systems.
Antecedents of venture firms' internationalization : A conjoint analysis of international entrepreneurship in the net economy
With the continuing dispersion of the global digital network and performance improvements of information and communication technologies, resource-poor start-ups with online business models have emerged in large numbers. These firms are able to deploy their competitive advantages across their country borders early in their life-cycle and engage in international commerce at a fast pace. An increased immediacy between the firms and the globally accessible customer is observed. Julia Christofor’s study aims to analyze the conditions of the initial internationalization decision in the Net Economy. Based on Information Systems, International Entrepreneurship, and Entrepreneurship literature, factors, which constitute the internationalization propensity, are derived. The results of this study suggest that a holistic perspective including the founder, business model and the firm level should be considered when explaining the internationalization propensity of entrepreneurs.
Antarctica : Contributions to Global Earth Sciences
Sixty articles arranged in eight thematic sections refer to most recent geological and geophysical results of Antarctic research. The Precambrian of the East Antarctic shield and its geological history is considered as well as sub-ice topography, geophysics and stratigraphy, sedimentology and geophysics of the surrounding Southern Ocean. Particular emphasis is given to the connection of the Antarctic and the surrounding continents when forming part of Gondwana.
Antarctic ecosystems : Environmental contamination, climate change, and human impact
This volume provides an overview of climate change data, its effects on the structure and functioning of Antarctic ecosystems, and the occurrence and cycling of persistent contaminants. It discusses the unique physico-chemical characteristics of the Antarctic environment, ecophysiological adaptations of terrestrial and marine organisms, the transfer of contaminants in pelagic and neritic food chains and the possible consequences for animals at higher trophic levels.
Ant Colony Optimization and Swarm Intelligence ; 6th International Conference, ANTS 2008, Brussels, Belgium, September 22-24, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th International Workshop on Ant Colony Optimization and Swarm Intelligence, ANTS 2008, held in Brussels, Belgium, in September 2008.
Ant Colony Optimization and Swarm Intelligence ; 5th International Workshop, ANTS 2006, Brussels, Belgium, September 4-7, 2006, Proceedings
ANTS – The International Workshop on Ant Colony Optimization and Swarm Intelligence is now at its ?fth edition. The series started in 1998 with the - ganization of ANTS 1998. At that time the goal was to gather in a common meeting those researchers interested in ant colony optimization: more than 50 researchers from around the world joined for the ?rst time in Brussels, Belgium, to discuss ant colony optimization and swarm intelligence related research. A selectionofthebest paperspresentedatthe workshopwaspublished asa special issue of the Future Generation Computer Systems journal (Vol. 16, No. 8, 2000). Two years later, ANTS 2000, organized again in Brussels, attracted more than 70 participants. The 41 extended abstracts presented as talks or posters at the workshopwere collected in a booklet distributed to participants, and a selection of the best papers was published as a special section of the IEEE Transactions on Evolutionary Computation (Vol. 6, No. 4, 2002).
Ansel's pharmaceutical dosage forms
Reflects the CAPE, APhA, and NAPLEX® competencies, and covers physical pharmacy, pharmacy practice, pharmaceutics, compounding, and dosage forms and the clinical application of the various dosing forms in patient care.
Another side of drugs
Drug interactions remain an important consequence of pharmacologic intervention. It is clear that the pharmacologic response of a drug can be markedly influenced by concurrent administration of another therapeutic agent or food. These interactions may result in a decreased therapeutic effect or in an increase in the amount and extent of untoward reactions. Despite the well-described and real clinical consequences of certain drug interactions, this aspect of patient care often continues to be overlooked.
Anomalies of the Developing Dentition : A Clinical Guide to Diagnosis and Management
This book is an up-to-date, succinct, and easily accessible reference on the diverse anomalies that may arise in the developing dentition, including those relating to crown size and shape, tooth formation, tooth eruption, tooth number, and enamel and dentin.
Annual bibliography of the history of the printed book and libraries ; Vol.31 : Publications of 2000 and additions from the preceding years
The Annual Bibliography of the History of the Printed Book and Libraries aims at recording articles of scholarly value which relate to the history of the printed book, to the history of arts, crafts, techniques and equipment, and of the economic social and cultural environment, involved in its production, distribution, conservation and description.
