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Thermodynamics for drug product design : A guide for pharmaceutical scientists
Provides real-life drug product design examples, applications, personal anecdotes, and solved problems that contextualize thermodynamic principles for the drug product design scientist. Advanced undergraduate and beginning graduate students will learn to apply thermodynamic principles to create robust drug products and to predict, prevent, analyze, and evaluate the root cause of product failures. Professionals engaged in drug product design will find this book to be a rich and easy to use reference guide.
Thermodynamics and Fluctuations far from Equilibrium
Sals with the formulation of the thermodynamics of chemical and other systems far from equilibrium, including connections to fluctuations. It contains applications to non-equilibrium stationary states and approaches to such states, systems with multiple stationary states, stability and equi-stability conditions, reaction diffusion systems, transport properties, and electrochemical systems. The theoretical treatment is complemented by experimental results to substantiate the formulation. Dissipation and efficiency are analyzed in autonomous and externally forced reactions, including several biochemical systems.
Thermodynamic equilibria and extrema : Analysis of attainability regions and partial equilibrium
Discusses mathematical models that are based on the concepts of classical equilibrium thermodynamics. They are intended for the analysis of possible results of diverse natural and production processes. Unlike the traditional models, these allow one to view the achievable set of partial equilibria with regards to constraints on kinetics, energy and mass exchange and to determine states of the studied systems of interest for the researcher. Application of the suggested models in chemical technology, energy and ecology is illustrated in the examples.
Thermal Processing of Packaged Foods
Thermal Processing of Packaged Foods, Second Edition, discusses the physical and engineering aspects of the thermal processing of packaged foods and examines the methods that have been used to establish the time and temperature of processes suitable to achieve adequate sterilization or pasteurization of the packaged food.New features in this edition include: The increased use of new packaging materials, including retortable pouches and the use of containers made from other plastic composite materials.
Thermal Decomposition of Solids and Melts : New Thermochemical Approach to the Mechanism, Kinetics and Methodology
Thermal Decomposition of Solids and Melts describes the results of investigations into the mechanisms and kinetics involved in the thermal decomposition of solid and liquid substances via thermochemical analysis (TA). The main features of these thermal decomposition reactions are explained within and the observed anomalies are interpreted. New methods of TA measurement and calculation have been developed, which permit the precision and accuracy of determination of kinetic parameters to be increased substantially. Reliable kinetic characteristics have been obtained and the decomposition mechanisms for several substances have been interpreted.
Thermal behaviour, energy efficiency in buildings and sustainable construction
This Special Issue includes 20 contributions from across the world with very interesting and current research topics, such as insulation solutions and CO2 emissions; thermal transmittance of LSF walls; statistics for China's building energy consumption; natural ventilation; thermal behavior of an earthbag building; thermal performance and comfort in a vernacular building; overheating risk under future extreme weather conditions.
Thermal and Power Management of Integrated Circuits
In Thermal and Power Management of Integrated Circuits, power and thermal management issues in integrated circuits during normal operating conditions and stress operating conditions are addressed. Thermal management in VLSI circuits is becoming an integral part of the design, test, and manufacturing.
Therapy Related Leukemia
As the population of cancer survivors continues to grow, there is a great need to term health of this population. Nearly one in five cancers -understand the longdiagnosed today occurs in an individual with a previous diagnosis of cancer, and cancers” are a leading cause of morbidity and mortality among these “second the etiology, prevention, and which reported esearchOur rcancer survivors. treatment of second cancers has the potential to improve public health, guide clinical management of survivors, and provide further insight into the mechanisms of carcinogenesis. Secondary cancer risk following radiotherapy and chemotherapy is an increasingly important topic in clinical oncology with impact on treatment decision making and on patient management. And one of the highest incidence was leukemia . Much of the evidence that underlies our understanding of secondary cancer risks and our risk estimates are derived from large epidemiologic studies that we will talk about it and predictive models of earlier decades with large uncertainties.
Theraputic targeting and drug delivery system
Smart drug delivery system (SDDS) is a recently emerging therapeutic approach now turning into a conventional model to deliver drug to specific sites or target. Drug targeted (DT) delivery systems maintains the concentration of the drugs at desirable doses in the body and avoid the need for repeated doses. The DT delivery system have specific distinguishing features such as self- regulated, pre-programmed, multi-targeted, controlled by timely response, monitoring of the targeted drug delivery, responsive to pH, and spatially targeted...
Thérapeutiques antiangiogéniques en cancérologie = Antiangiogenic therapeutics in oncology
The fundamental role of angiogenesis in tumor growth and spread has been known for over 30 years now. We have recently had effective anti-angiogenic drugs on many tumors. Their use requires a good knowledge of their mode of action, their side effects, their indications and their place in the therapeutic strategy. This work is therefore divided into three points: - It is first recalled the important role of tumor angiogenesis, the means available to evaluate it on histological samples, its practical modalities of use and the side effects of anti-cancer drugs. -angiogenic.- Then the therapeutic results obtained with the anti-VEGF antibodies and the anti-VEGFR tyrosine kinase inhibitors are detailed for each of the tumors.- Finally, the positioning of these new molecules in the multidisciplinary strategy is discussed. - view of other processing methods.
Therapeutic use of medicinal plants and their extracts ; Vol.1: Pharmacognosy
This volume focuses on the importance of therapeutically active compounds of natural origin. Natural materials from plants, microbes, animals, marine organisms and minerals are important sources of modern drugs. Beginning with two chapters on the development and definition of the interdisciplinary field of pharmacognosy, the volume offers up-to-date information on natural and biosynthetic sources of drugs, classification of crude drugs, pharmacognosical botany, examples of medical application, WHO´s guidelines and intellectual property rights for herbal products.
Therapeutic medicinal plants in traditional persian medicine
Traditional Persian Medicine (TPM) is one of the oldest medical doctrines, globally known due to pioneering physicians and scientists. The greatest source of natural medicines in TPM originates from medicinal plants. Therapeutic Medicinal Plants in Traditional Persian Medicine provides a background on the history of TPM, as well as an introduction to 40 of the most popular medicinal plants used in TPM. It is a practical guide for readers interested in medicinal plants used in the prevention, management, and treatment of different diseases.
Therapeutic Management of Incontinence and Pelvic Pain : Pelvic Organ Disorders
Chapters include coverage of the management and treatment of bladder and bowel dysfunctions in men and women, pelvic organ prolapse; issues concerning the elderly, neurologically impaired patients and those with pelvic pain. Allied updated chapters are presented on research methodology, the importance of fluids and infection control. Other new chapters are concerned with quality of life, the treatment of bladder and bowel dysfunction in children, the history of pelvic floor muscle exercise and manual therapy. In addition, the use of real-time ultrasound to evaluate pelvic floor muscle contractility, exercise balls to promote coordination of trunk stabilisers and the pelvic floor muscles, and the role of the Occupational Therapist in the continence service are discussed. Finally, a new section on ethical issues regarding the management of incontinence completes this well-illustrated text.
Therapeutic Lipidology ; 2nd ed.
The chapters focus on recent advances in the field including novel biomarkers and the microbiome, genomics of cardiovascular risks, PCSK9 inhibitors, imaging technologies, and epidemiology of atherosclerotic cardiovascular disease. The book describes new guidelines, novel therapeutic agents, and changes in the understanding of specific lipoproteins and subclasses with regard to their relationships to cardiovascular disease risk. The second edition contains more than thirty chapters covering such topics as the history of lipidology, lipoprotein metabolism and vascular biology, disorders of lipid metabolism, lifestyle/dietary and pharmacologic management for dyslipidemia, the management of dyslipidemia in certain subgroups (e.g., women, children, older patients) and lipid testing, as well as an examination of other biomarkers and testing procedures related to atherosclerosis and cardiovascular disease.
Theory of Random Sets
Theory of Random Sets presents a state of the art treatment of the modern theory, but it does not neglect to recall and build on the foundations laid by Matheron and others, including the vast advances in stochastic geometry, probability theory, set-valued analysis, and statistical inference of the 1990s. The book is entirely self-contained, systematic and exhaustive, with the full proofs that are necessary to gain insight. It shows the various interdisciplinary relationships of random set theory within other parts of mathematics, and at the same time, fixes terminology and notation that are often varying in the current literature to establish it as a natural part of modern probability theory, and to provide a platform for future development.
Theory of Periodic Conjugate Heat Transfer
A new calculation method is presented for heat transfer in coupled convective-conductive fluid-wall systems under periodical intensity oscillations in fluid flow. It is demonstrated that the true steady-state mean value of the heat transfer coefficient has to be multiplied by a newly defined coupling factor. This correction factor is always smaller than one and depends on the coupling parameters Biot number, Fourier number as well as dimensionless geometry and oscillation parameters. For characteristic periodic heat transfer problems, analytical solutions are given for the coupling factor. To facilitate engineering application, the monograph also presents the analytical results in accompanying tables and diagrams.
Theory of Mind and Language in Developmental Contexts
Blazes new trails in the study of the relationship between the theory of mind--that is, the ability to attribute mental states as the basis of behavior and social interaction--and language. This volume examines the linguistic variables within developmental contexts, including: Different levels of analysis. Intercultural differences (e.g., Western, non-Western). Intracultural differences (e.g., socioeconomic status). Conditions of development as well as typical and atypical functions. Contexts of usage, including personal, social, and business interactions.
Theory of experience in architecture and urban design
Starts from the conception of architectural space as a continuum that goes from the subjective depth of the mind to the objective reality, taking into consideration the perspective of building experiences for users. It is based on the idea that at the heart of that continuum is the experience of architecture and the city as the element that unites them and gives them meaning.The book is divided into two parts. The first part defines what the architectural experience is from the processes of perception, cognition, and evaluation that users and architects make about workplaces and programs. It deals with the phenomenology of the architectural experience from what creates the sense of place and then looks at the taxonomy of the areas of experience and the implications for the architect’s work processes.The second part of the book deals with the knowledge and use of tools for the diagnosis of users and places.
Theory of Cryptography ; 4th Theory of Cryptography Conference, TCC 2007, Amsterdam, The Netherlands, February 21-24, 2007, Proceedings
TCC 2007, the Fourth Theory of Cryptography Conference, was held in Amsterdam, The Netherlands, from February 21 to 24, 2007, at Trippenhuis, the headquarters of the Royal Dutch Academy of Arts and Sciences (KNAW). TCC 2007 was sponsored by the International Association for Cryptologic Research (IACR) and was organized in cooperation with the Cryptology and Information Security Group at CWI, Amsterdam; the Mathematical Institute, Leiden University; and DIAMANT, the Dutch national mathematics cluster for discrete interactive and algorithmic algebra and number theory. The General Chair of the conference was Ronald Cramer.
Theory of Concrete-Filled Steel Tubular Structures
This textbook focuses on concrete-filled steel tubular structures formed by placing concrete inside the steel tube. The content addresses some key technical issues of concrete-filled steel tubular members, such as the mechanical properties of steel and core concrete, the shrinkage and creep of core concrete, the bonding behavior between steel tube and core concrete, the limiting values for the initial stress of steel tube caused by construction load and the void of core concrete, the protective design of concrete-filled steel tubular members under chloride corrosive environment and impact loading, etc. This textbook also discusses the technology and design principles of concrete-filled steel tubular hybrid structures.
