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Requirements Management : The Interface Between Requirements Development and All Other Systems Engineering Processes
Requirements Management has proven itself to be an enormous potential for the optimization of development projects throughout the last few years. Especially in the climate of an increasingly competitive market Requirements Management helps in carrying out developments faster, cheaper and with a higher quality. This book focuses on the interfaces of Requirements Management to the other disciplines of Systems Engineering, for example Project Management, Change Management and Configuration and Version Management. To this end, an introduction into Requirements Management and Requirements Development is given, along with a short sketch of Systems Engineering, and especially the necessary inputs and resulting outputs of Requirements Management are explained. Using these flows of information it is shown how Requirements Management can support and optimize the other project disciplines and how very important therefore a functioning Requirements Management is for all areas of development.
Renewables for Energy Access and Sustainable Development in East Africa
Investigates the role of renewable energy in East Africa to provide policy-relevant inputs for the achievement of a cost-effective electrification process in the region. For each country, the authors review the current situation in the domestic power sector, adopt a GIS-based approach to plot renewable energy resources potential, and review currently planned projects and projects under development, as well as the key domestic renewables regulations.
Prostate Cancer : Biology, Genetics, and the New Therapeutics
The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth
Progress in the chemistry of organic natural products. Vol.106
Coumarin chemistry remains one of the major interest areas of phytochemists, especially because of their structural diversity and medicinal properties, along with the wide-ranging bioactivities of these compounds, inclusive of analgesic, anticoagulant anti-HIV, anti-inflammatory, antimicrobial, antineoplastic, antioxidant, and immunomodulatory effects. The second contribution presents a comprehensive survey of the many aspects of PAD biochemistry and physiology. The third contribution gives a comprehensive overview of secondary metabolites from higher fungi, with more than 700 references highlighting the isolation, structure elucidation, biological activities, chemical synthesis, and biosynthesis of pigments, nitrogen-containing compounds, and terpenoids from mushrooms.
Progress in the Chemistry of Organic Natural Products 112
The first chapter describes the oldest method of communication between living systems in Nature, the chemical language. Plants, due to their lack of mobility, have developed the most sophisticated way of chemical communication. The second chapter is focused on the natural products obtained from Hypericum L., a genus of the family Hypericaceae within the dicotyledones. Hypericum has been valued for its important biological and chemical properties and its use in the treatment of depression and as an antibacterial has been well documented in primary literature and ethnobotanical reports. The present contribution gives a comprehensive summary of the chemical constituents and biological effects of this genus. The third chapter addresses microtubule stabilizers, which are a mainstay in the treatment of many solid cancers and are often used in combination with molecularly targeted anticancer agents and immunotherapeutics.
Progress in the Chemistry of Organic Natural Products 111
The first chapter in volume 111 summarizes research on the sesterterpenoids, which are known as a relatively small group of natural products. However, they express a variety of simple to complicated chemical structures. This chapter focuses on the chemical structures of sesterterpenoids and how their structures are synthesized in Nature. The second chapter is devoted to marine-derived fungi, which play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological activities that make them useful leads for drug discovery. Marine natural product research in China in general has made enormous progress in the last two decades as described in this chapter on fungal metabolites.
Progress in the Chemistry of Organic Natural Products 109
This volume comprises three reviews. The first describes isolation, structure determination, syntheses, and biochemistry of the low molecular weight compounds of the secretion of exocrine glands of termies with emphasis to pheromones and defensive compounds. The second review describes recent studies on isolation and structure elucidation of bioactive compounds involved in the life cycle and determination of the molecular mechanisms of the developmental events observed in higher plants. The third contribution reports on the current body of knowledge of African propolis, with a particular emphasis on its chemistry and biological activity.
Progress in the Chemistry of Organic Natural Products 108
It summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. It is also provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses.It discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria.
Progress in the Chemistry of Organic Natural Products 107
It describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types.The reported pharmacological activities of the new and known alkaloids showed a greater bias towards central nervous system and related activities. Other prominent activities reported were antifeedant or insecticidal, cytotoxicity/antitumor/anticancer/estrogenic, antiprotozoal, antiinflammatory, antioxidant, antifungal and antiviral activities.
Programming languages : Principles and paradigms
Programming Languages is a self-contained approach to the topic, and differentiates between the design, implementation and pragmatic aspects of programming languages overall. The main programming paradigms are presented, in a straightforward way.
Probability Distributions Involving Gaussian Random Variables : A Handbook for Engineers and Scientists
This handbook, now available in paperback, brings together a comprehensive collection of mathematical material in one location. It also offers a variety of new results interpreted in a form that is particularly useful to engineers, scientists, and applied mathematicians. The handbook is not specific to fixed research areas, but rather it has a generic flavor that can be applied by anyone working with probabilistic and stochastic analysis and modeling.
Pro JSP 2
This is the first comprehensive guide to cover JSP 2 and 2.1. It supplies you with the tools and techniques to develop web applications with JSP and Java servlets. You'll learn to choose and implement the best persistence option for your web applications, and how to secure web sites against malicious attack and accidental misuse. You will improve the performance and scalability of JSP pages, as well as architect reliable, stable applications.
Principles and practice of phytotherapy : Modern herbal medicine
Covers all major aspects of herbal medicine from fundamental concepts, traditional use and scientific research through to safety, effective dosage and clinical applications. Written by herbal practitioners with active experience in clinical practice, education, manufacturing and research, the textbook is both practical and evidence based. The focus, always, is on the importance of tailoring the treatment to the individual case. New insights are given into the herbal management of approxiately 100 modern ailments, including some of the most challenging medical conditions, such as asthma, inflammatory bowel disease and other complex autoimmune and inflammatory conditions, and there is vibrant discussion around the contribution of phytotherapy in general to modern health issues, including health ageing.
Potassium channels : Methods and protocols
Explores the widespread involvement of K+ channels in cellular processes, which makes these membrane proteins intriguing targets for both fundamental scientific inquiry and the development of pharmaceutical compounds. The chapters in this book provide an in-depth look at various techniques and the latest protocols commonly used in ion channel research to investigate K+ channel structures, functions, and their interactions with drugs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Policies and Research in Identity Management ; 1st IFIP WG11.6 Working Conference on Policies and Research in Identity Management (IDMAN'07), RSM Erasmus University, Rotterdam, The Netherlands, October 11-12, 2007
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of refereed international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research.
PET : Physics, Instrumentation, and Scanners
Derived from the critically acclaimed reference PET: Molecular Imaging and Its Biological Applications, edited by Michael E. Phelps, Ph.D., this handbook provides a clear and concise introduction to the physics and instrumentation aspects of PET imaging. Comprised of select material from the parent volume, this book is gives the reader a solid understanding of PET fundamentals, including how PET data are collected and formed into an image. Other topics include basic physics, detector technology used in modern PET scanners, data acquisition, 3-D reconstruction, and methods for evaluating the performance of PET systems.
Parallel and Distributed Computing : Applications and Technologies ; 5th International Conference, PDCAT 2004, Singapore, December 8-10, 2004, Proceedings
The technical program was comprehensive and featured keynote speeches, te- nical paper presentations, and exhibitions showcased by industry vendors. The technical program committee was overwhelmed with submissions of papers for presentation, from countries worldwide. We received 242 papers and after - viewing them, based on stringent selection criteria, we accepted 173 papers. The papers in the proceedings focus on parallel and distributed computing viewed from the three perspectives of networking and architectures, software systems and technologies, and algorithms and applications. We acknowledge the great contribution from all of our local and international committee members and - per reviewers who devoted their time in the review process and provided valuable feedback for the authors. PDCAT 2004 could never have been successful without the support and ass- tance of several institutions and many people.
Oxford textbook of plastic and reconstructive surgery
A comprehensive reference text detailing all aspects of plastic surgery pertinent to a surgeon in training for specialisation and suitable to use in preparation for the Intercollegiate Examination as all aspects of the curriculum are covered. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris.
Oral Lichen planus and lichenoid lesions : Etiopathogenesis, diagnosis and treatment
Highlights the main discoveries and the limits of current knowledge in the epidemiology, pathogenesis and therapy of this oral disorder, projecting clinicians to the best possible therapeutic management and researchers to the main research fields potentially interesting for the understanding of etiopathogenesis and the establishment of a universally recognized diagnostic criteria.
Nutrition, Health and Disease : A Lifespan Approach
Delivers an easy-to-read and student-friendly textbook on the changing demands for nutrients made by the body throughout the human lifespan.
