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Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Natural occurrence and biological activities of quinoline derivatives
Provides a comprehensive overview of quinoline derivatives, focusing on their chemical structure, biological activities, and therapeutic benefits. It delves into the natural sources of these derivatives, covering their isolation, characterization, and potential therapeutic applications, particularly in areas such as anti-cancer, anti-inflammatory, antimicrobial, and antimalarial activity. With its emphasis on providing valuable reference material, this book is an indispensable resource for researchers, educators, and professionals in the fields of chemistry, biology, pharmacology, and drug discovery.
National Institute of Allergy and Infectious Diseases, NIH ; Vol.1 : Frontiers in Research
National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research contains presentations given at the 2006 NIAID Research Conference held in Opatija, Croatia which brought internationally known researchers from the United States and Central and Eastern Europe to focus together on shared interests in microbiology, infectious disease, HIV/AIDS, and basic and clinical immunology. Some of the topics covered include emerging and re-emerging infections, the development of infectious disease prophylactics and therapeutics, drug resistance, and various topics in immunomodulation, autoimmunity, infections and immunity, and the development of vaccines.Extensive and in-depth, National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research is a valuable, comprehensive guide to the state of research today.
Nanotribology and nanomechanics : An introduction ; 2nd ed.
This volume serves as a timely, practical introduction to the principles of nanotribology and nanomechanics and applications to magnetic storage systems, MEMS/NEMS and BioMEMS/bioNEMS. Assuming some familiarity with macrotribology/mechanics, the book comprises chapters by internationally recognized experts, who integrate knowledge of the field from the mechanics and materials-science perspectives. They cover key measurement techniques, their applications, and theoretical modelling of interfaces, each beginning their contributions with macro- and progressing to microconcepts
Nanotribology and nanomechanics : An introduction ; 1st ed.
This volume serves as a timely, practical introduction to the principles of nanotribology and nanomechanics and applications to magnetic storage systems and MEMS/NEMS. Assuming some familiarity with macrotribology/mechanics, the book comprises chapters by internationally recognized experts, who integrate knowledge of the field from the mechanics and materials-science perspectives. They cover key measurement techniques, their applications, and theoretical modelling of interfaces, each beginning their contributions with macro- and progressing to microconcepts.
Nanotechnology-Enabled Sensors
Nanotechnology provides us with tools to create functional materials, devices, and systems by controlling materials at the atomic and molecular scales, and at the same time make use of novel properties and phenomena. Considering that most chemical and biological sensors, as well as many physical sensors, depend on interactions occurring within the nano scale range, the impact that nanotechnology will have on the sensor world is significant. Nanotechnology enabled sensors find applications in several novel fields such as sensing single molecules, bio-hazards, toxic chemicals, gas sensors, process control and diagnostics.
Nanotechnology for Smart Concrete
Nanomaterials can markedly improve the mechanical properties of concrete, as well as reduce the porosity and enhance the durability of concrete. The application of nanotechnology in concrete is still in its infancy. However, an ever-growing demand for ultra-high-performance concrete and recurring environmental pollution caused by ordinary Portland cement has encouraged engineers to exploit nanotechnology in the construction industry. Nanotechnology for Smart Concrete discusses the advantages and applications of nanomaterials in the concrete industry, including high-strength performance, microstructural improvement, self-healing, energy storage, and coatings. The book: Analyses the linkage of concrete materials with nanomaterials and nanostructures / Discusses the applications of nanomaterials in the concrete industry, including energy storage in green buildings, anti-corrosive coatings, and inhibiting pathogens and viruses / Covers self-healing concrete / Explores safety considerations, sustainability, and environmental impact of nanoconcrete / Includes an appendix of solved questions
Nanotechnology for Microfluidics
The book focuses on microfluidics with applications in nanotechnology. The first part summarizes the recent advances and achievements in the field of microfluidic technology, with emphasize on the the influence of nanotechnology. The second part introduces various applications of microfluidics in nanotechnology, such as drug delivery, tissue engineering and biomedical diagnosis.
Nanotechnology based cosmetics
Explores the applications and advantages of nanotechnology-based cosmetic products compared to conventional formulations. It examines the principles and mechanisms of nanotechnology in enhancing cosmetic product efficacy, delivery, and performance. Key applications covered include nanoparticles for sunscreens, nanoencapsulation for controlled release, nanoemulsions, liposomes for targeted delivery, and antimicrobial nanoparticles. Analyzes case studies from major international cosmetic companies utilizing nanotechnology. It also discusses challenges like safety concerns, potential toxicity, regulations, labeling, consumer awareness, and environmental impact.
Nanostructures : Fabrication and Analysis
The main theme of this book is the exploration the underlying physical laws that permit the fabrication of nanometer-scale structures. As researchers attempt to fabricate nanometer-scale structures which do not exist per se, they must still employ the natural laws to fabricate them through processes such as self-assembly. So it turns out that our techniques for fabrication of nanometer-scale structures are not artificial but actually rely on the natural laws. We even find that nanometer-scale structures, e.g. fullerenes, are fabricated in nature beneath the surface of the Earth. This fact may be called the ubiquity of the nanometer-scale structures. The topics presented in the book include: scanning probe-related and near-field techniques, nanolithography, self assembling and design of novel nanostructures, as well as new nanodevices and their application.
Nanostructured Soft Matter : Experiment, Theory, Simulation and Perspectives
This book provides an interdisciplinary overview of a new and broad class of materials under the unifying name Nanostructured Soft Matter. It covers materials ranging from short amphiphilic molecules to block copolymers, proteins, colloids and their composites, microemulsions and bio-inspired systems.
Nanostructured Coatings
Controlling the performance of structures and components of all sizes and shapes through the use of engineered coatings has long been a key strategy in materials processing and technological design. The ever-increasing sophistication of en- neered coatings and the rapid trend toward producing increasingly smaller devices with greater demands on their fabrication, properties and performance have led to signicant progress in the science and technology of coatings, particularly in the last decade or two. Nanostructured coatings constitute a major area of sci- ti?c exploration and technological pursuit in this development.Nanostructured coatings demand study in a highly interdisciplinary research arena which encompasses: surface and interface science study of defects modern characterization methodologies cutting-edge experimental developments to deposit.
Nanostructured and advanced materials for applications in sensor, optoelectronic and photovoltaic technology ; Proceedings of the NATO Advanced Study Institute on nanostructured and advanced materials for applications in sensors, optoelectronic and photovoltaic technology ; Sozopol, Bulgaria, 6-17 September 2004
Nanotechnology is an emerging scientific field receiving significant worldwide attention. On a nanometer scale, materials or structures may possess new and unique physical properties. Some of these are now known to the scientific community, but there may well be many properties not yet known to us, rendering it as a fascinating area of research and a suitable subject for a NATO ASI. Yet another aspect of the field is the possibility for creating meta-stable phases with unconventional properties and the ultra-miniaturization of current devices, sensors, and machines. Such nanotechnological and related advanced materials have an extremely wide range of potential applications, viz. nanoscale electronics, sensors, optoelectronics, photonics, nano-biological systems, na- medicine, energy storage systems, etc. This is a wide-ranging subject area and therefore requires the formation of multi-disciplinary teams of physicists, chemists, materials scientists, engineers, molecular biologists, pharmacologists, and others to work together on the synthesis and processing of materials and structures, the understanding of their physical properties, the design and fabrication of devices.
Nanoscience : Nanotechnologies and Nanophysics
Nanotechnologies and nanosciences are a fast-developing field of research, which sit at the point of convergence of several disciplines (physics, chemistry, biology, mechanics, etc.). This practically-oriented overview is designed to provide students and researchers with essential information on both the tools of manufacture and specific features of the nanometric scale, as well as applications within the most active fields (electronics, magnetism, information storage, biology).
Nanoscale Photonic Imaging
This book, edited and authored by a team of world-leading researchers, provides a broad overview of advanced photonic methods for nanoscale visualization, as well as describing a range of fascinating in-depth studies.
Nanoscale Phenomena : Basic Science to Device Applications
Nanotechnology is the result of the continuing technological trend toward device miniaturization and the characterization, manipulation, and fine control of structure and function at diminishing length scales. A large class of nanoscale materials can be stable even though they are far from the lowest-energy thermodynamic state, and many possess novel properties unattainable in bulk. These trends are supported by the increasing sophistication of characterization and fabrication tools such as the scanning tunneling microscope and the transmission electron microscope, which allow the resolution and manipulation of single atoms and molecules.
Nanopharmaceutical advanced delivery systems
Provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. Deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. Elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc.
Nanomedicine : Innovations, applications, and breakthroughs in the quest for health and medicine's future
Revolutionizing healthcare, by providing innovative solutions to some of the most challenging issues in medicine. This book provides an in-depth overview of nanoscale materials and devices that are advancing diagnostics, therapeutics, and personalized care in medical field. It focuses on nanomedicine’s impact on vaccine efficacy as well as innovative diagnosis and therapy for various type of cancer while addressing concerns about safety and toxicity. It examines how nanotechnology is enhancing drug delivery by precisely targeting medicines to specific cells or tissues, thereby increasing treatment efficacy with reduced side effects. Explores how nanoparticles are advancing medical imaging for earlier and more accurate disease detection, and how nanosensors allow real-time biomarker monitoring for faster and more reliable diagnoses. Additionally, it explores nanomedicine's role in managing cardiovascular diseases, improving bone health through nano-extracellular vesicles, and regenerative medicine, including ongoing clinical trials and ethical considerations.
Nanomechanics of Materials and Structures
This book is derived from the proceedings of the International Workshop on Nanomechanics held at Asilomar Conference Grounds in Pacific Grove, California on July 14-17, 2004. The main objective was to convene leading researchers in the nanotechnology community to assess the current state-of-the-art and disseminate recent progress, critical issues, barriers to applications, and directions for future research in nanomechanics.
Nano- and Micromaterials
The future focus of nanotechnology will be on realizing new functions over greater scales. This book describes the creation of nano- and microscale structures and functions by controlling temperature, light, pressure, or carrier injections. It covers novel nano-integration technologies such as quantum-well devices possilbe by utilizing, for example, the self-organization of surface nanostructures and optically or pressure-induced phase transitions, micro machines using microstereolithography, as well as new techniques of laser spectroscopy and new computational methods for estimating atomic and electronic structures and their functions on the nano- and microscales.
