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Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders : Novel Strategies for Research and Treatment
Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders.
Neural Information Processing ; Vol. 4234 ; 13th International Conference, ICONIP 2006, Hong Kong, China, October 3-6, 2006, Proceedings, Part III
This book and its companion volumes constitute the Proceedings of the 13th - ternationalConferenceonNeuralInformationProcessing(ICONIP2006)heldin Hong Kong during October 3–6,2006. ICONIP is the annual ?agship conference oftheAsiaPaci?cNeuralNetworkAssembly(APNNA)withthepasteventsheld in Seoul (1994), Beijing (1995), Hong Kong (1996), Dunedin (1997), Kitakyushu (1998), Perth(1999), Taejon(2000), Shanghai(2001), Singapore(2002), Istanbul (2003), Calcutta(2004), andTaipei(2005). Overtheyears, ICONIPhasmatured into a well-established series of international conference on neural information processing and related ?elds in the Asia and Paci?cregions. Following the tra- tion, ICONIP 2006 provided an academic forum for the participants to diss- inate their new research ?ndings and discuss emerging areas of research.
Neural Information Processing ; Vol. 4232 ; 13th International Conference, ICONIP 2006, Hong Kong, China, October 3-6, 2006, Proceedings, Part I
This book and its companion volumes constitute the Proceedings of the 13th - ternationalConferenceonNeuralInformationProcessing(ICONIP2006)heldin Hong Kong during October 3–6,2006. ICONIP is the annual ?agship conference oftheAsiaPaci?cNeuralNetworkAssembly(APNNA)withthepasteventsheld in Seoul (1994), Beijing (1995), Hong Kong (1996), Dunedin (1997), Kitakyushu (1998), Perth(1999), Taejon(2000), Shanghai(2001), Singapore(2002), Istanbul (2003), Calcutta(2004), andTaipei(2005). Overtheyears, ICONIPhasmatured into a well-established series of international conference on neural information processing and related ?elds in the Asia and Paci?cregions. Following the tra- tion, ICONIP 2006 provided an academic forum for the participants to diss- inate their new research ?ndings and discuss emerging areas of research.
NETWORKING 2006 : Networking technologies, services, protocols ; performance of computer and communication networks ; Mobile and wireless communications systems ; 5th International IFIP-TC6 Networking Conference, Coimbra, Portugal, May 15-19, 2006, Proceedings
Networking 2006 was organized by the University of Coimbra, Portugal, and it was the fifth event in a series of International Conferences on Networking sponsored by the IFIP Technical Committee on Communication Systems (TC 6). Previous events were held in Paris (France) in 2000, Pisa (Italy) in 2002, Athens (Greece) in 2004, and Waterloo (Canada) in 2005. Networking 2006 brought together active and proficient members of the networking community, from both academia and industry, thus contributing to scientific, strategic, and practical advances in the broad and fast-evolving field of communications. The conference comprised highly technical sessions organized thematically, keynote talks, tutorials offered by experts, as well as workshops and panel discussions on topical themes. Plenary sessions with keynote talks opened the daily sessions, which covered Networking Technologies, Services and Protocols, Performance of Computer and Communication Networks, and Mobile and Wireless Communications Systems.
Networking -- ICN 2005 ; Vol. 3420 : 4th International Conference on Networking, Reunion Island, France, April 17-21, 2005, Proceedings, Part I
The International Conference on Networking (ICN 2005) was the fourth conf- ence in its series aimed at stimulating technical exchange in the emerging and important ?eld of networking. On behalf of the International Advisory C- mittee, it is our great pleasure to welcome you to the proceedings of the 2005 event. Networking faces dramatic changes due to the customer-centric view, the venue of the next generation networks paradigm, the push from ubiquitous n- working, and the new service models. Despite legacy problems, which researchers and industry are still discovering and improving the state of the art, the ho- zon has revealed new challenges that some of the authors tackled through their submissions. In fact ICN 2005 was very well perceived by the international networking community. A total of 651 papers from more than 60 countries were submitted, from which 238 were accepted. Each paper was reviewed by several members of the Technical Program Committee. This year, the Advisory Committee revalidated various accepted papers after the reviews had been incorporated. We perceived a signi?cant improvement in the number of submissions and the quality of the submissions. The ICN 2005 program covered a variety of research topics that are of current interest, starting with Gridnetworks, multicasting, TCP optimizations, QoS and security, emergency services, and network resiliency. The Program Committee selected also three tutorials and invited speakers that addressed the latest - search results from the international industries and academia, and reports on ?ndings from mobile, satellite, and personal communications related to 3rd- and 4th-generation research projects and standardization.
Netherlands yearbook of international law 2019 : Yearbooks in international law : History, function and future
This volume of the Netherlands Yearbook of International Law (NYIL) is the fiftieth in the Series, which means that the NYIL has now been with us for half a century. The editors decided not to let this moment go by unnoticed, but to devote this year's edition to an analysis of the phenomenon of yearbooks in international law.The Netherlands Yearbook of International Law was first published in 1970. It offers a forum for the publication of scholarly articles in a varying thematic area of public international law.
Net Neutrality or Net Neutering : Should Broadband Internet Services Be Regulated
The subject of this book – whether or not to extend traditional telecommunications regulation to high-speed or "broadband" access to the Internet – is perhaps the most important issue now facing the Federal Communications Commission. The issue is also very contentious, with influential economic interests as well as academics on both sides of the question. Content providers – Microsoft and Amazon, for instance – argue that broadband providers should be treated as common carriers, required to transmit all content in a nondiscriminatory way. The broadband providers – the telephone and cable companies – argue that no bottleneck monopoly exists to justify such regulation and that, if imposed, it would stifle development of the Internet.
Neoproterozoic Geobiology and Paleobiology
The Neoproterozoic Era (1000-542 million years ago) is a geological period of dramatic climatic change and important evolutionary innovations. Repeated glaciations of unusual magnitude occurred throughout this tumultuous interval, and various eukaryotic clades independently achieved multicellularity, becoming more complex, abundant, and diverse at its termination. Animals made their first debut in the Neoproterozoic too. The intricate interaction among these geological and biological events is a centrepiece of Earth system history, and has been the focus of geobiological investigations in recent decades. The purpose of this volume is to present a sample of views and visions among some of the growing numbers of Neoproterozoic workers. The contributions represent a cross section of recent insights into the field of Neoproterozoic geobiology.
Nearest Neighbor Search : A Database Perspective
Modern applications are both data and computationally intensive and require the storage and manipulation of voluminous traditional (alphanumeric) and nontraditional data sets (images, text, geometric objects, time-series). Examples of such emerging application domains are: Geographical Information Systems (GIS), Multimedia Information Systems, CAD/CAM, Time-Series Analysis, Medical Information Sstems, On-Line Analytical Processing (OLAP), and Data Mining. These applications pose diverse requirements with respect to the information and the operations that need to be supported. From the database perspective, new techniques and tools therefore need to be developed towards increased processing efficiency. This monograph explores the way spatial database management systems aim at supporting queries that involve the space characteristics of the underlying data, and discusses query processing techniques for nearest neighbor queries. It provides both basic concepts and state-of-the-art results in spatial databases and parallel processing research, and studies numerous applications of nearest neighbor queries.
Nb3Sn Accelerator Magnets : Designs, Technologies and Performance
This book is written by world-recognized experts in the fields of applied superconductivity and superconducting accelerator magnet technologies. It provides a contemporary review and assessment of the experience in research and development of high-field accelerator dipole magnets based on Nb3Sn superconductor over the past five decades. The reader attains clear insight into the development and the main properties of Nb3Sn composite superconducting wires and Rutherford cables, and details of accelerator dipole designs, technologies and performance. Special attention is given to innovative features of the developed Nb3Sn magnets. The book concludes with a discussion of accelerator magnet needs for future circular colliders.
Navigating Numeracies : Home/School Numeracy Practices
The book aims to further understanding of why some pupils have low achievement in numeracy in the school context. The authors aim to achieve this by a relatively original view that focuses on numeracy as a social practice. They report on their investigations into the meanings and uses of numeracy in school and home and community contexts, using ethnographic-style approaches, including formal and informal interviews and observations. The book will be useful for policy, practice and further research into the teaching and learning of mathematics in schools. It will therefore be of interest to policy makers, teachers and practitioners, academics and practitioners in teacher education, education researchers, and parents and community leaders.
Nature-Based Flood Risk Management on Private Land : Disciplinary Perspectives on a Multidisciplinary Challenge
This book addresses the various disciplinary aspects of nature-based solutions in flood risk management on private land. In recent decades, water management has been moving towards nature-based solutions. These are assumed to be much more multi-purpose than traditional “grey infrastructures” and seem to be regarded as a panacea for many environmental issues. At the same time, such measures require more – and mostly privately owned – land and more diverse stakeholder involvement than traditional (grey) engineering approaches. They also present challenges related to different disciplines. Nature-based solutions for flood risk management not only require technical expertise, but also call for interdisciplinary insights from land-use planning, economics, property rights, sociology, landscape planning, ecology, hydrology, agriculture and other disciplines to address the challenges of implementing them. Ultimately, nature-based flood risk management is a multi-disciplinary endeavor.
Natural Polysaccharides in Drug Delivery and Biomedical Applications
Provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field.Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process.
NASAs Scientist-Astronauts
Mounting pressure in the early 1960s from the National Academy of Sciences (NAS) to study ways of expanding the role of astronauts to conduct science on future space missions led to NASA’s conclusion that flying scientifically trained crewmembers would generate greater returns from each mission. NASA and industry studies continued investigating possibilities that could lead to the eventual creation of the first space stations using surplus Apollo hardware, through the Apollo Applications Programme (AAP).
Narrowing the Achievement Gap : Strategies for Educating Latino, Black, and Asian Students
This volume is an important and impressive collection of scholarship that addresses one of the more intractable education problems of our times--ensuring that ALL children receive a quality education." -- Gloria Ladson-Billings, Kellner Family Professor in Urban Education University of Wisconsin at Madison, and 2005-2006 President of AERA "A major contribution to the field, the in-depth analyses provided by the chapter authors should be of substantial appeal to a wide audience because of its interdisciplinary approach and orientation to theory, research, and practice." -- Stanley Sue, Distinguished Professor of Psychology and Asian American Studies University of California at Davis "In considering the broad problems and in recommending solutions, the book provides breadth, concision, and unique organization." -- Edmund W. Gordon, John M.
Nanostructured Coatings
Controlling the performance of structures and components of all sizes and shapes through the use of engineered coatings has long been a key strategy in materials processing and technological design. The ever-increasing sophistication of en- neered coatings and the rapid trend toward producing increasingly smaller devices with greater demands on their fabrication, properties and performance have led to signicant progress in the science and technology of coatings, particularly in the last decade or two. Nanostructured coatings constitute a major area of sci- ti?c exploration and technological pursuit in this development.Nanostructured coatings demand study in a highly interdisciplinary research arena which encompasses: surface and interface science study of defects modern characterization methodologies cutting-edge experimental developments to deposit.
Nanoscaled Semiconductor-on-Insulator Structures and Devices
This proceedings volume constitutes an archive of the contributions of the key-speakers who attended the NATO Advanced Research Workshop on “Nanoscaled Semiconductor-On-Insulator Structures and devices” held in the Tourist and Recreation Centre “Sudak” (Crimea, Ukraine) from 15 to 19 October 2006. The semiconductor industry has sustained a very rapid growth during the last three decades through impressive technological developments which have resulted in products with higher performance and lower cost per function. After many years of development it is now confidently predicted that semiconductor-on-insulator materials will enter and increasingly be used by manufacturing industry. The wider use of semiconductor (es- cially silicon) on insulator materials will not only enable the benefits of these materials to be demonstrated but, also, will drive down the cost of substrates which, in turn, will stimulate the development of other novel devices and applications.
Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems
Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
Nanoformulations in Human Health: Challenges and Approaches
This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
Nanocrystals : Synthesis, Properties and Applications
Nanocrystals and Their Mesoscopic Organization is an up-to-date monograph on an important aspect of nanoscience and technology. It opens with an elegant introduction including a brief historical account. Emphasis is then given to diverse synthetic methods, both chemical and physical, in addition to modern hybrid methods. The orientation shifts gradually to properties of nanocrystals that evolve with size; detailed discussions are to be found on mesoscalar assemblies in different dimensions, special cases of core-shell and magic nuclearity nanocrystals. The authors also address applications of nanocrystals, carefully separating out potential applications and those that have already emerged, and cite around 900 references from the literature, most from the last decade. Tables providing information at a glance and schematic diagrams at relevant places, make the monograph appealing to read.
