Page 25
Page 25
Drug safety evaluation : Methods and protocols
Focuses on the most recent advances in the field of drug safety evaluation. Divided into seven parts, chapters detail specific aspects related to the experimental design of preclinical studies conducted to support the safety of pediatric and combination drugs, necropsy and histopathology evaluation, mass spectrometry imaging, genetic toxicology protocols including the Pig-a mutation assay, safety pharmacology methods such as automatization of patch-clamp procedures, target safety assessment for investigative toxicology, screening assays for developmental toxicology, and methods to characterize novel translational safety biomarkers like microRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.
Drug residues in animal products
The use of veterinary drugs in food-producing animals has the potential to generate residues in animal derived products (meat, milk, eggs and honey) and poses a health hazard to the consumer. There are many factors influencing the occurrence of residues in animal products such as drug's properties and their pharmacokinetic characteristics, physicochemical or biological processes of animals and their products. The most likely reason for drug residues might be due to improper drug usage and failure to keep the withdrawal period...
Drawing with a tablet : Easy techniques for mastering digital drawing on location
learn step by step how to create amazing drawings while on the go. Shows sketchers how to take their digital drawing to the next level. Whether you are new to sketching or wish to try the latest technology, this useful guide shares expert tips and techniques for drawing on a tablet. With a focus on using the ProCreate tool, but with information that is relevant to other digital platforms, you will start with the basics, such as opening your file, choosing your resolution, determining your palette, and how to simplify your tools by creating a preferred set of brushes.Covers using layers and groups of layers, and shows you how to create a sketch from start to finish.
Doing Cross-Cultural Research : Ethical and Methodological Perspectives
Conducting cross-cultural research is rife with methodological, ethical and moral challenges. Researchers are challenged with many issues in carrying out their research with people in cross-cultural arenas. In this book, I attempt to bring together salient issues for the conduct of culturally appropriate research. The task of undertaking cross-cultural research can present researchers with unique opportunities, and yet dilemmas. The book will provide some thought-provoking points so that our research may proceed relatively well and yet ethical in our approach. The subject of the book is on the ethical, methodological, political understanding and practical procedures in undertaking cross-cultural research.
Do Exclusionary Rules Ensure a Fair Trial? : A Comparative Perspective on Evidentiary Rules
This publication discusses exclusionary rules in different criminal justice systems. It is based on the findings of a research project in comparative law with a focus on the question of whether or not a fair trial can be secured through evidence exclusion. Part I explains the legal framework in which exclusionary rules function in six legal systems: Germany, Switzerland, People’s Republic of China, Taiwan, Singapore, and the United States. Part II is dedicated to selected issues identified as crucial for the assessment of exclusionary rules. These chapters highlight the delicate balance of interests required in the exclusion of potentially relevant information from a criminal trial and discusses possible approaches to alleviate the legal hurdles involved.
Disturbed soil properties and geotechnical design
Describes the developments leading to the Original Cam Clay model, focusing on fundamentals of the shearing of soil. The aim is to lay the groundwork of understanding that should form the basis of geotechnical design, guiding engineers towards the class of behaviour to be expected under different combinations of effective stress and water content.
Distribution and phenotype of proliferating cells in the Forebrain of adult macaque monkeys after transient global cerebral ischemia
The authors' results show that ischemia differentially activates endogenous neural precursors residing in diverse locations of the adult primate central nervous system. A limited endogenous potential for postischemic neuronal repair exists in neocortex and striatum, but not in the hippocampus proper of the adult macaque monkey brain. The presence of putative parenchymal progenitors and of sustained progenitors in germinative centers opens novel possibilities for precursor cell recruitment.
Distributed Computing and Internet Technology ; 4th International conference, ICDCIT 2007, Bangalore, India, December, 17-20, 2007, Proceedings
The book is covering a range of issues from basic technology, through services and engineering, to applications, from development issues, through middleware support, to actual delivery of e-Society services.
Distributed and Parallel Systems : From Cluster to Grid Computing
This book devoted to general algorithmic aspects of parallel and distributed computing and grid computing. This book includes a good overview of recent advances in various aspects of parallel and distributed computing. This volume also includes various crucial questions tied to the infrastructure and advanced problems and challenges of grid computing.
Dissipative Systems Analysis and Control : Theory and Applications
Dissipative Systems Analysis and Control (second edition) presents a fully revised and expanded treatment of dissipative systems theory, constituting a self-contained, advanced introduction for graduate students, researchers and practising engineers. It examines linear and nonlinear systems with examples of both in each chapter; some infinite-dimensional examples are also included. Throughout, emphasis is placed on the use of the dissipative properties of a system for the design of stable feedback control laws. The theory is substantiated by experimental results and by reference to its application in illustrative physical cases (Lagrangian and Hamiltonian systems and passivity-based and adaptive controllers are covered thoroughly).
Disrupted Development and the Future of Inequality in the Age of Automation
This book examines the future of inequality, work and wages in the age of automation with a focus on developing countries. The authors argue that the rise of a global ‘robot reserve army’ has profound effects on labor markets and economic development, but, rather than causing mass unemployment, new technologies are more likely to lead to stagnant wages and premature deindustrialization.
Discovery Science ; 11th International Conference, DS 2008, Budapest, Hungary, October 13-16, 2008. Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Discovery Science, DS 2008, held in Budapest, Hungary, in October 2008, co-located with the 19th International Conference on Algorithmic Learning Theory, ALT 2008.
Discovery Science ; 10th International Conference, DS 2007 Sendai, Japan, October 1-4, 2007. Proceedings
This volume consists of three parts. The first part contains the papers/abstracts of the invited talks, the second part contains the accepted long papers, and the third part contains the accepted regular papers.
Discoveries in Photosynthesis
Conceived of as a way of summarizing the history of research advances in photosynthesis as of millennium 2000, the book evolved into a majestic and encyclopedic saga involving all of the basic sciences. This book is meant not only for the researchers and graduate students, but also for advanced undergraduates in Plant Biology, Microbiology, Cell Biology, Biochemistry, Biophysics and History of Science.
Disciplines and Doctorates
Advice about how to achieve a PhD usually falls short of relevance because the ways of creating and reporting knowledge differ dramatically from one disciplinary field and specialisation to another. Yet supervisors and doctoral candidates alike know that there are certain protocols or parameters, often inexplicit in nature, that govern its achievement and that need to be mastered. This book sets out to explore the nature of these protocols and parameters, linking them to the cognate characteristics of fields of knowledge and to social conventions constraining how new knowledge is reported.
Directing the Story : Professional Storytelling and Storyboarding Techniques for Live Action and Animation
You will learn classic visual storytelling techniques such as conveying meaning with images and directing the viewer's eye. Glebas also teaches how to spot potential problems before they cost time and money, and he offers creative solutions on how to solve them. Uses the classic story of '1001 Arabian Nights' to show how to storyboard stories that will engage an audience's attention and emotions. With 1001 drawings in graphic novel format plus teaching concepts and commentary. All of the storyboarding examples have a real project context rather to engage a very visual audience on their own terms and teaches through demonstration
Digital VLSI Systems Design : A Design Manual for Implementation of Projects on FPGAs and ASICs Using Verilog
The book presents new material and theory as well as synthesis of recent work with complete Project Designs using industry standard CAD tools and FPGA boards, enabling the serious readers to design VLSI Systems on their own. The reader is taken step by step through the design right from implementing a single digital gate to a massive design consuming well over 100,000 gates. The Verilog codes developed for these designs are universal and can work on any FPGA or ASIC and are technology independent. The book presents the development of novel algorithms and architectures for optimum realization of high tech. products. All the design codes developed in this book are Register Transfer Level (RTL) compliant and can be readily used or amended to suit new projects.
Digital video concepts, methods, and metrics : Quality, compression, performance, and power trade-off analysis
Digital Video Concepts, Methods, and Metrics: Quality, Compression, Performance, and Power Trade-off Analysis is a concise reference for professionals in a wide range of applications and vocations. It focuses on giving the reader mastery over the concepts, methods and metrics of digital video coding, so that readers have sufficient understanding to choose and tune coding parameters for optimum results that would suit their particular needs for quality, compression, speed and power.
Digital Timing Measurements : From Scopes and Probes to Timing and Jitter
As many circuits and applications now enter the Gigahertz frequency range, accurate digital timing measurements have become crucial in the design, verification, characterization, and application of electronic circuits. To be successful in this endeavour, an engineer needs a knowledge base covering instrumentation, measurement techniques, signal integrity, jitter and timing concepts, and statistics. Very often even the most experienced digital test engineers, while mastering some of those subjects, lack systematic knowledge or experience in the high speed signal area.
Digital Libraries : Universal and Ubiquitous Access to Information ; 11th International Conference on Asian Digital Libraries, ICADL 2008, Bali, Indonesia, December 2-5, 2008. Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Asian Digital Libraries, ICADL 2008, held in Bali, Indonesia, in December 2008.
