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Biomarkers for alzheimer’s disease drug development
Helping to accelerate Alzheimer’s disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer’s disease field are performed.
Bioinformatics for oral cancer : Current insights and advances
Offering a deep dive into the multifaceted landscape of oral cancer research and bioinformatics. Readers will uncover a wealth of knowledge, starting with foundational chapters introducing bioinformatics and establishing the backdrop of oral cancer. The book then progresses into the realm of diagnostic biomarkers, revealing cutting-edge methodologies for their identification in the context of oral cancer. The book’s keen focus extends to gene expression profiles and the intricacies of gene sequencing in the context of oral cancer progression.
Biogeochemical cycles in globalization and sustainable development
This valuable study of environmental subsystems functioning under various climatic and anthropogenic conditions provides a unique insight into the social context of global changes in biogeochemical cycles and demonstrates current understanding of globalization and sustainable development.
Biodiversity-health-sustainability Nexus in socio-ecological production landscapes and seascapes (SEPLS)
It is a compilation of case studies that provide useful knowledge and lessons that derive from on-the-ground activities and contribute to policy recommendations, focusing on the interlinkages between biodiversity and multiple dimensions of health (e.g., physical, mental, and spiritual) in managing socio-ecological production landscapes and seascapes (SEPLS). This book provides insights on how SEPLS approaches can contribute to more sustainable management of natural resources, achieving global biodiversity and sustainable development goals, and good health for all. It is also expected to offer useful knowledge and information for an upcoming three-year thematic assessment of “the interlinkages among biodiversity, water, food, and health” (the so-called “nexus assessment”) by the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES). The book begins with an introductory chapter followed by eleven case study chapters demonstrating the nexus between biodiversity, health, and sustainable development, and then a synthesis chapter clarifying the relevance of the case study findings to policy and academic discussions. It will be of interest to scholars, policymakers, and professionals in the field related to sustainable development.
Biochemistry of Atherosclerosis
Advances in Biochemistry in Heath and Disease presents state-of-the-art discussions in cutting-edge biochemical research, offering exciting developments that impact healthcare and disease research. Volumes in the series focus on cross-disciplinary biomedical research and examine various topics in biochemistry, cell biology, molecular biology, and biomedicine. Biochemistry of Atherosclerosis examines atherosclerosis in great detail, focusing on the risk of atherosclerosis, and the biochemical pathways involved. It provides a breadth of knowledge as well as new insights into a variety of topics relating to atherosclerosis from leading scientists around the world who are at the forefront of atherosclerosis research. Biochemistry of Atherosclerosis is essential reading for biomedical and clinical researchers.
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Benign anorectal diseases : Diagnosis with endoanal and endorectal ultrasound and new treatment options
New three-dimensional endoanal and endorectal ultrasonographic and magnetic resonance imaging techniques have given better insight into the complex anatomy of the pelvic floor and its pathologic modification in benign anorectal diseases. Obstetrical events leading to fecal incontinence in females, the relationship between fistulous tracks and the sphincter complex, and mechanisms of obstructed defecation syndrome can now be accurately evaluated, which is of fundamental importance for decision making.
Behavioral pharmacology of the cholinergic system
The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
Beginning Game Development with Python and Pygame : From novice to professional
Beginning Game Development with Python and Pygame is written with the budding game developer in mind, introducing games development through the Python programming language and the popular Pygame games development library. You'll be privy to insights that will not only help you to exploit Pygame to its maximum potential, but also make you a more creative and knowledgeable games developer all round.
Beginning Excel What-If Data Analysis tools : Getting started with goal seek, data tables, scenarios, and solver
Excels what-if data analysis tools let you experiment with your data to project future results. In turn, these predictions will lead to better decision making and unlock the mystery of many business analysis scenarios. For example, what-if data analysis tools will enable you to forecast how lowering the price per unitwhile increasing projected unit salesmight affect your profit margins. Beginning Excel What-If Data Analysis Tools explores the use of Goal Seek, Data Tables, Scenarios, and Solver to help you get insight on your data. This book is focused and to the point, and it provides tutorial treatment of what-if tools in a practical, hands-on manner.
Becoming a teacher educator : Theory and practice for teacher educators
It is the first book that addresses a range of important topics related to the work of teacher educators, the induction of teacher educators and their further professional development.Becoming a Teacher Educator has a practical focus and it provides theoretical insights, experiences of experts and practical recommendations. The book is rooted in the Association of Teacher Education in Europe (ATEE) and many of the chapters are written by authors who are active members of the ATEE. Distinguished researchers and practitioners from different parts of Europe, and beyond, joined their efforts to write a book that is truly international and combines research, practice and reflection.
Basic theoretical physics : A concise overview
This concise treatment embraces, in four parts, all the main aspects of theoretical physics (I . Mechanics and Basic Relativity, II. Electrodynamics and Aspects of Optics, III. Non-relativistic Quantum Mechanics, IV. Thermodynamics and Statistical Physics). It summarizes the material that every graduate student, physicist working in industry, or physics teacher should master during his or her degree course. It thus serves both as an excellent revision and preparation tool, and as a convenient reference source, covering the whole of theoretical physics. It may also be successfully employed to deepen its readers' insight and add new dimensions to their understanding of these fundamental concepts. Recent topics such as holography and quantum cryptography are included, thus making this a unique contribution to the learning material for theoretical physics.
Basic & Clinical Pharmacology
Covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Banks and fintech on platform economies : Contextual and conscious banking
In Banks and Fintech on Platform Economies: Contextual and Conscious Banking, accomplished fintech professional and author Paolo Sironi delivers an insightful examination of how platform theory, born outside of financial services, will make its way inside banking and financial markets to radically transform the way firms do business.
Bacterial Physiology : A Molecular Approach
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.
Automating business modelling : A guide to using logic to represent Informal methods and support reasoning
Enterprise Modelling (EM) methods are frequently used by entrepreneurs as an analysis tool for describing and redesigning their businesses. The resulting product, an enterprise model, is commonly used as a blueprint for reconstructing organizations and such effort is often a part of business process re-engineering and improvement initiatives. Automating Business Modelling describes different techniques of providing automated support for enterprise modelling methods and introduces universally used approaches. A running example of a business modelling method is included; providing a framework and detailed explanation as to how to construct automated support for modelling, allowing readers to follow the method to create similar support. Suitable for senior undergraduates and postgraduates of Business Studies, Computer Science and Artificial Intelligence, practitioners in the fields of Knowledge Management, Enterprise Modelling and Software Engineering, this book offers insight and know-how to both student and professional.
Automatic Differentiation : Applications, Theory, and Implementations
This collection covers the state of the art in automatic differentiation theory and practice. Practitioners and students will learn about advances in automatic differentiation techniques and strategies for the implementation of robust and powerful tools. Computational scientists and engineers will benefit from the discussion of applications, which provide insight into effective strategies for using automatic differentiation for design optimization, sensitivity analysis, and uncertainty quantification.
Attention in Cognitive Systems : Theories and Systems from an Interdisciplinary Viewpoint ; 4th International Workshop on Attention in Cognitive Systems, WAPCV 2007 Hyderabad, India, January 8, 2007 Revised Selected Papers
The embodied nature of sensory-motor intelligence requires a continuous and focused interplay between the control of motor activities and the interpretation of feedback from perceptual modalities. Decision making about the selection of information from the incoming sensory stream – in tune with contextual processing on a current task and an agent’s global objectives – becomes a further challenging issue in attentional control. Attention must operate at interfaces between bottom-up driven world int- pretation and top-down driven information selection, thus acting at the core of arti?cial cognitive systems. These insights have already induced changes in AI-related disciplines, such as the design of behavior-based robot control and the computational modeling of animats. Today, the development of enabling technologiessuch as autonomous robotic systems,miniaturizedmobile–evenwearable–sensors,andambientintelligence systems involves the real-time analysis of enormous quantities of data. These data have to be processed in an intelligent way to provide “on time delivery” of the required relevant information. Knowledge has to be applied about what needs to be attended to, and when, and what to do in a meaningful sequence, in correspondence with visual feedback.
Attention deficit hyperactivity disorder (ADHD) : Awareness in Syrian communities
Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting both children and adults, characterized by inattention, hyperactivity, and impulsivity. This research explores ADHD awareness, prevalence, diagnosis, and treatment preferences within Syrian communities. A survey was conducted to collect data from individuals regarding their awareness of ADHD, its diagnosis, and treatment preferences. Additionally, interviews with specialists provided insights from medical professionals on the diagnosis and management of ADHD.
Atlas of endomicroscopy
Deals with the new insights of endomicroscopy and provides you an overview about the development, the requirements, the technique, current indications and further possibilities of endomicroscopy.
