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The NeuroProcessor : An integrated interface to biological neural networks
This book presents the Neuroprocessor, a novel computational neuronal interface device implemented in VLSI technology. In addition to neuronal signals acquisition, it can process the data, generate stimuli and transmit the data over wireless channels, while using minimum electric energy.
The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy.
The neuregulin-I/ErbB signaling system in development and disease
This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.
The Network Collective : Rise and Fall of a Scientific Paradigm
The network paradigm dominated immunological research from the early 1970s to the late 1980s. The originator, Niels Jerne, hypothesized that the vast diversity of antibodies in each individual forms a network of mutual ""idiotypic"" recognition, thus regulating the immune system. In context of emerging concepts of systems biology such as cybernetics and autopoesis, the ""Eigenbehavior"" of the immune system fascinated an entire generation of young immunologists. But fascination led to experimental errors and overinterpretation, eventually magnifying the immune system from a mere infection-fighting device to a substrate of personality and individuality. As a result, what initially appeared as an exciting new perspective of the immune system is now viewed as a scientific vagary, and is largely abandoned.
The Neolithic Demographic Transition and its Consequences
The methodological innovation which has made possible the identification of the NDT is the use of a relative chronology, fixed to the local onset of the Neolithic. That is, events are considered not in terms of their absolute calendar dates, but rather in terms of their relation to the local date of the transition to agriculture. This volume presents and discusses the consequences and implications of the NDT on a global scale. Topics include: The causes of the NDT at its onset / Indicators of economic intensification as related to the NDT / Settlement and village practices associated with the pace of the NDT / The emergence of social practices associated with larger population concentrations / The effects of increased population density on human health.
The Myc/Max/Mad Transcription Factor Network
Intense study of the enigmatic myc proto-oncogene over the last 20 years has broadened our view of its functions and led to insights into transcriptional regulation as well as cancer etiology, cell proliferation, apoptosis, and organismal development. How can one gene be involved in so many aspects of cellular behavior? Of particular interest is the fact that the Myc protein functions as part of a network (comprising Myc, Max, and Mad proteins) whose specific interactions direct transcriptional activation or repression of a large number of target genes. The chapters in this volume examine both molecular and biological aspects of the Myc/Max/Mad network. Included are contributions concerning the regulation of its expression, the mechanisms underlying its diverse transcriptional activities, the structural bases for its critical interactions, and the nature of its target genes. Other chapters explore the evolution of the network, its role in development and genomic instability, and the evidence for a parallel transcriptional network. Overall, this volume provides a broad and current overview of research on a crucial group of transcription factors.
The muskellunge symposium : A memorial tribute to E.J. Crossman
This book documents proceedings of a symposium on muskellunge developed as a memorial for E.J. Crossman. It focuses on the biology, ecology, and management of muskellunge, Ed’s favorite fish. The papers include surveys of current ecological, behavioral, and management-related issues for muskellunge fisheries. The symposium was developed to bring researchers and anglers together, and was sponsored by Muskies, Inc. The papers focus on issues of importance to muskellunge populations and are developed to inform the public and fishery managers alike.
The Morality of Business : A Profession for Human Wealthcare
That business is benevolent, positive, and honorable might seem a difficult argument given the hostility among intellectuals, academics, artists and pundits towards this essentially benevolent profession. In this thought-provoking book, The Morality of Business: A Profession for Human Wealthcare, Machan argues that business, like medicine, enhances human life, and that it is indeed a thoroughly decent profession for people to choose to enter, in order to best serve the worthy goal of promoting all around prosperity. He goes beyond the utilitarian case, that business serves society quite well, to contend that caring for one's own economic well being is prudent, that enhancing the wealth of one's household is a proper objective, and to serve clients in the capacity of managing their wealth successfully is every bit as honorable as serving patients with their health needs. The result is a positive statement, in the tradition of Adam Smith and David Hume, addressing some of the most controversial topics of today, including job "security," outsourcing, and government regulation.
The Moral, Social, and Commercial Imperatives of Genetic Testing and Screening : The Australian Case
This is a dynamic book that successfully combines global and local thinking with regard to an emerging technology that will contribute to the expansion of proteomics and pharmacogenomics, the science of tailored healthcare and treatments. Genetic testing and screening will change the way people understand health, diagnostic knowledge, illness but also crime, databases and private information, paternity, and self-knowledge. In addition to giving individuals the opportunity to think differently about their well-being, it installs a new taxonomy in terms of illness, because its probabilistic effects will introduce a new narrative in the health discourse of 21st century society. While in the past people could be classified as being healthy or sick, now, through genetic testing and screening, adults can be classified as being healthy, predisposed to an illness, probably at risk, at risk, or carriers of certain risks. The effects of this taxonomy do not remain confined to the individual who is tested but extends to an entire family, as genetic knowledge is family knowledge. But the technology of genetic testing and screening installs a second dramatic register in the prenatal phase when cells and embryos are tested and subsequently altered in order to hit targets of perfection.
The molecular targets and therapeutic uses of curcumin in health and disease
Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. More than 1500 papers published within last half a century has revealed that curcumin has a potential in the treatment of wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer, psoriasis etc, through modulation of numerous molecular targets. This is the first monograph to deal specifically with this subject.
The Molecular Mechanisms of Axenfeld-Rieger Syndrome
Annotation The Molecular Mechanisms of Axenfeld-Rieger Syndrome describes the current research and clinical findings of the heterogeneous disorder termed Axenfeld-Rieger Syndrome (ARS). The book provides an in-depth analysis of this phenotypic diverse disorder and is designed to detail the current molecular and biochemical research involved in studying genetic defects. This book brings together the complete analysis of a human genetic defect using humans, mouse and chick epigenetic and genetic studies, combined with cell culture and in vitro analyses. It is a comprehensive study of a unique set of genes and their mutant activities. A molecular basis for the genetic and phenotypic anomalies observed in ARS patients is provided, with especially detailed descriptions of eye, tooth, and heart development.
The Molecular Genetics of Lung Cancer
Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.
The Middle Parana River : Limnology of a Subtropical Wetland
This book details the recent advances in the knowledge of the most important segment of the Parana River, organized according to the scientific structure of the National Institute of Limnology of Argentina (INALI-CONICET-UNL).
The Method of Approximate Inverse : Theory and Applications
Inverse problems arise whenever one tries to calculate a required quantity from given measurements of a second quantity that is associated to the first one. Besides medical imaging and non-destructive testing, inverse problems also play an increasing role in other disciplines such as industrial and financial mathematics. Hence, there is a need for stable and efficient solvers. The book is concerned with the method of approximate inverse which is a regularization technique for stably solving inverse problems in various settings such as L2-spaces, Hilbert spaces or spaces of distributions.
The Metabolic Syndrome in Clinical Practice
Metabolic Syndrome in Clinical Practice addresses current issues and interactions surrounding metabolic syndrome, obesity, diabetes and cardiovascular disease.
The Medical City in Kalamoon = المدينة الطبية في القلمون
ملخص المشروع: للمدينة الطبية في القلمون ثلاث وظائف رئيسية 1- مجمع المستشفيات ويضم: - مستشفى القلب والكلى - مستشفى الأورام - مستشفى زراعة الأعضاء والأطراف الصناعية - المستشفى التخصصي للأنف والعين والأذن والوجه والفكين - مستشفى الجلدية و النسائية و التوليد - قسم العيادات العامة والأمراض المزمنة كل الخدمات التي تحتاجها هذه المستشفيات 2- المركز الصحي العلاجي وخدماته 3-دائرة الايواء والسكن للاطباء والممرضات والعاملين وكل ما تحتاجه للخدمات
The Medical Basis of Psychiatry
The major goal of the this edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders.
The medical activity of salvadora persica
The human mouth is inhabited from birth by many types and numbers of microbes that are both beneficial and harmful to the health of the mouth and teeth. Either. Multiple factors in the oral environment contribute to the multiplication and diversity of microbes, including in particular the regularity of natural teeth. The cleanliness and maintenance of artificial dentures, the amount of integrity and vitality of gum tissue and ligaments around the age, as well as an important factor relates to food quality. In the mouth, saliva deposits protein-sugar compounds that form thin, transparent layers called pellicle. The surfaces of the teeth (enamels), which helps the oral microbes to adhere to these layers and thus multiply and accumulate in large quantities and in the form of thin organic layers known as microbial dental plaque on the surfaces of the teeth, above and below edge of the gum. It is scientifically proven that if the teeth are not cleaned well or regularly daily and if the accumulation of plaque continues.
The Management of Transshipment Terminals : Decision Support for Terminal Operations in Finished Vehicle Supply Chains
Multinational companies aim at strategic competitive advantages by distributing their activities around the globe. As a result, the in dividual supply chains become longer and more complex. Next to the supply chain reliability, companies try to keep supply chains cost effi cient and responsive, i.e. warrant short order fulfillment lead times (Siirie and Wagner, 2005). The above goals dictate low inventory levels at the stages of a supply chain as well as a high frequency of transports between the partners involved. Supply Chain Requirements. Detailed performance measures for a supply chain are provided by the Supply Chain Operations Refer ence (SCOR) model (Supply-Chain Council, 2002).
The Making of a Neuromorphic Visual System
The book reviews theories of visual object and shape recognition in the fields of computer vision, neuroscience and psychology. The entire range of computations is discussed, as for example contour extraction in retinal circuits, orientation determination in cortical networks, position and scale independence of shape, as well as the issue of object and shape representation in a neural substrate.
