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Cell Surface Receptors : A Short Course on Theory and Methods
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
Celebrating applied sciences reaches 20,000 articles milestone: invited papers in "applied dentistry and oral sciences" section
Encompasses a wide range of disciplines, covering everything from dental materials and biomaterials to preventive and therapeutic strategies, from clinical applications to regenerative dentistry.We envision this milestone as a stepping stone toward even greater accomplishments. Through the collaboration and collective efforts of researchers worldwide, we strive to push the boundaries of dental science, explore new frontiers, and improve oral health outcomes for individuals across the globe.
Case studies in the traditional food sector : A volume in the consumer science and strategic marketing series
The book explores how consumer and sensory science has been implemented in the food industry for achieving the following strategic aims: Rejuvenating product image, Shaping new market places, Achieving market differentiation and geographical diffusion, Achieving customer loyalty, Promoting traditional features of the product and defining product positioning in competitive environment. This book aims to answer the following questions, amongst others: How research in the field of consumer science became relevant for marketing strategies?, Which tangible economic and financial outcomes have been obtained by the joint work of sensory scientists, Researchers in marketing field and food business professionals?, And which communication methods and practices have been relevant to make the most of R&D in the food industry?
Cartilage Repair Strategies
Cartilage Repair Strategies is a comprehensive update of the present state of cartilage repair and regeneration. The information in this volume addresses what methods are effective, what methods are safe, and what methods will lead to an alteration in the short history of articular cartilage injury repair. Contributors present examinations of a variety of topics including the structure and function of articular cartilage, the evaluation of cartilage repair techniques, and the latest cartilage sensitive imaging techniques.
Carcinoma della cervice uterina : Eziopatogenesi e profilassi = Carcinoma of the uterine cervix : Aetiopathogenesis and prophylaxis
The volume offers a synthetic and updated picture of a complex topic that includes the multifactorial etiopathogenesis of cervical cancer, the characteristics of the virus, the dynamics of HPV infections, the histological lesions of the cervix leading to cervical cancer. and the characteristics of the various surgical treatments, the current strategies for early diagnosis through the use of molecular assays currently on the market, up to the trials of the two vaccines recently registered also in Italy.
Cancer vaccination and challenges Vol.2 : delivery strategies for cancer vaccine and immunotherapy in the management of various carcinomas
Covers delivery strategies of cancer vaccines for the management of various forms of carcinoma, examining the prospects of delivering immuno-oncology therapies, focusing specifically on effective drug delivery strategies for the treatment of lung, prostate, and pancreatic carcinomas.
Cancer vaccination and challenges Vol.1 : strategies for therapeutic cancer vaccine development
Deals with different strategies of cancer vaccine development, focusing on techniques for the development of therapeutic cancer vaccines and the roles of tumor antigens, proteins/peptides, microbial genes, and stem cells for the development of vaccines for cancer management.
Cancer Proteomics : From Bench to Bedside
the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Cancer in adolescents and young adults
The chapters highlight the initial efforts of this Committee in addressing the scope of the problem of adolescent and young adult underrepresentation in clinical trials and offer evidence that such adiscrepancy may partially explain outcome differences.In addition, these chapters present information about biologic differences between specific cancer subtypes most common in younger children and those exhibited by the same cancers in adolescents and young adults, and offer plausible explanations for outcome differences as well as potential treatment strategies.
Cancer Gene Therapy
the authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation
Cancer Clinical Trials : Proactive Strategies
The ever-changing regulations for clinical trials and the ethical dilemma of treating cancer patients as subjects have made it ever so difficult for the principal investigators to conduct clinical research, especially when they are often ill-informed of the complex nature of the regulations and over-worked. Therefore, cancer clinical trials are at a critical junction. The objective of this book is to bring the issues of cancer clinical trials into focus so that proactive strategies may be developed to make such trials more user-friendly. Ultimately, the cancer patients will be benefited.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Cadmium toxicity : challenges and solutions
Offers a comprehensive collection of review and case chapters that cover cadmium toxicity and remediation. It covers sources of cadmium contamination, its impact on human health, and prospective remediation strategies, taking a multi-disciplinary approach a focus on application of recent advanced biological technology. The chapters here bring together a diverse group of environmental science, sustainability and health researchers to address the challenges caused by cadmium contamination, explaining the routes of exposure to environmental cadmium, how cadmium is transported in ecosystems, and the health risks linked to cadmium exposure in food and the environment.
Business and Professional Ethics
Learn why ethical behavior is so important and how to recognize potential pitfalls that involve much more than memorizing rules. You master the skills to develop a corporate culture of integrity that maintains stakeholder support and enables directors and auditors to complete their jobs. You also learn how to use ethical strategies to make decisions, as this edition examines the latest information on governance scandals, legal liability and professional accounting and auditing issues.
Building the Agile Business through Digital Transformation
Building the Agile Business through Digital Transformation is an in-depth guide for all those needing to better understand, implement and lead digital transformation in the workplace. It sets aside traditional thinking and outdated strategies to explain what steps need to be taken for an organization to become truly agile, embed innovation and develop talent to succeed.
Building Services Design for Energy Efficient Buildings
"The following issues are addressed: background issues on climate change, whole-life performance and design collaboration / generic strategies for energy efficient, low-carbon design / health and wellbeing and post occupancy evaluation / building ventilation / air conditioning and HVAC system selection / thermal energy generation and distribution systems / low-energy approaches for thermal control / electrical systems, data collection, controls and monitoring / building thermal load assessment / building electric power load assessment / space planning and design integration with other disciplines."
Bringing the Jobless into Work? : Experiences with Activation Schemes in Europe and the US
Over the last decade, many industrialized countries shifted from passive unemployment and welfare benefit regimes and traditional active labor market and social policies to activation strategies by making benefit receipt conditional upon accepting job offers or participation in active labor market schemes. But countries differ with regard to the design of activation instruments and their implementation, the definition of target groups and the effects of activation in the national labor market setting. This volume provides an up-to-date overview of activation strategies in unemployment benefit systems and social assistance in selected European countries and the US. A particular focus lies on the development of activation schemes, governance and implementation as well as on the outcomes of activation in terms of labor market and social integration. The volume is the first to address these issues both from a socio-economic and a legal perspective.
Bridging laboratory and field research for genetic control of disease vectors
Contemporary research on genetic control of disease-transmitting insects knows two kinds of scientists: those that work in the laboratory and those known as ‘field people’. Over the last decade, both groups seem to have developed differing research priorities, address fundamentally different aspects within the overall discipline of infectious-disease control, and worse, have developed a scientific ‘language’ that is no longer understood by the ‘other’ party. This gap widens every day, between the North and the South, between ecologists and molecular biologists, geneticists and behaviourists, etc. The need to develop a common research agenda that bridges this gap has been identified as a top priority by all parties involved. Only then shall the goal of developing appropriate genetic-control strategies for vectors of disease become reality.
Bridge Management 5 : Inspection, maintenance, assessment and repair ; Proceedings of the 5th International Conference on Bridge Management, organized by the University of Surrey, 11–13 April 2005
The last five years have seen the art of bridge management develop into a mature subject. Bridge owners and engineers recognise the importance of implementing fully operational bridge management strategies to ensure that all road and rail bridges remain functional for as long as possible.Bridge structures form a major part of the vast financial investment in infrastructure and consequently their careful management involving structural appraisal, repair and strengthening is of paramount importance.
Branch-and-Bound Applications in Combinatorial Data Analysis
There are a variety of combinatorial optimization problems that are relevant to the examination of statistical data. Combinatorial problems arise in the clustering of a collection of objects, the seriation (sequencing or ordering) of objects, and the selection of variables for subsequent multivariate statistical analysis such as regression. The options for choosing a solution strategy in combinatorial data analysis can be overwhelming. Because some problems are too large or intractable for an optimal solution strategy, many researchers develop an over-reliance on heuristic methods to solve all combinatorial problems. However, with increasingly accessible computer power and ever-improving methodologies, optimal solution strategies have gained popularity for their ability to reduce unnecessary uncertainty. In this monograph, optimality is attained for nontrivially sized problems via the branch-and-bound paradigm.
