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Basic concepts in medicinal chemistry

Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. Specific sections of the text have been updated to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills.

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Basic bundle theory and K-Cohomology invariants

Based on several recent courses given to mathematical physics students, this volume is an introduction to bundle theory with the aim to provide newcomers to the field with solid foundations in topological K-theory. A fundamental theme, emphasized in the book, centers around the gluing of local bundle data related to bundles into a global object. One renewed motivation for studying this subject, which has developed for almost 50 years in many directions, comes from quantum field theory, especially string theory, where topological invariants play an important role.

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Basic Algebra

Basic Algebra and Advanced Algebra systematically develop concepts and tools in algebra that are vital to every mathematician, whether pure or applied, aspiring or established. Together, the two books give the reader a global view of algebra and its role in mathematics as a whole.Basic Algebra presents the subject matter in a forward-looking way that takes into account its historical development. It is suitable as a text in a two-semester advanced undergraduate or first-year graduate sequence in algebra, possibly supplemented by some material from Advanced Algebra at the graduate level. It requires of the reader only familiarity with matrix algebra, an understanding of the geometry and reduction of linear equations, and an acquaintance with proofs.

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Baseband Analog Circuits for Software Defined Radio

Baseband Analog Circuits for Software Defined Radio aims to describe the transition towards a Software Radio from the analog design perspective. A complete overview of the actual state-of-art for reconfigurable transceivers is given in detail, focusing on the challenges imposed by flexibility in analog design.

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Basal Implantology

Helps oral implantologists to understand the principles that underlie the use of basal implants as a means to provide simple solutions to complex and highly demanding clinical situations without the need for prior bone grafting.

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Barry's Introduction to Construction of Buildings ; 4th ed.

Based mainly on domestic and residential buildings—and filled with extensive illustrations throughout—this concise text is the ideal introduction to the subject of building construction. It provides the basic material that readers need in order to understand the construction process for the majority of low rise buildings. The book explains construction technology through the key functional and performance requirements for the main elements common to all buildings. With a strong focus on building efficiency and meeting the challenges posed by limiting the environmental impact of buildings, and new “at a glance” summaries allowing you to grasp the salient points of each chapter, readers will find the text fully up to date with the latest building regulations and construction technology. Deals with design, technology, site assembly, and environmental issues of domestic and residential buildings. Thoroughly updated, with particular attention paid to the concept of building efficiency and improved integration of the topics covered to match current student needs. New “at a glance” summaries at the beginning of each chapter.

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Barriers and Biases in Computer-Mediated Knowledge Communication : And How They May Be Overcome

This books deals with computer-mediated cooperation and communication scenarios in teaching and learning situations, leisure activities (e.g. laypersons looking for expert information on the internet), and net-based communication at work. Such scenarios will become increasingly important. But the successful use of such computer-mediated settings is not trivial. Cooperative learning and work itself requires special skills and strategies. And the technical settings with sometimes restricted, sometimes new possibilities for communication add problems on top of the cooperation itself. What are the barriers in computer-mediated communication for cooperative learning and work? Which are the most relevant biases in computer-mediated information processing? Based on empirical research the contributors from psychology, education and computer sciences offer different perspectives on the nature and causes of such barriers.

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Barile's clinical toxicology : Principles and mechanisms ; 3rd ed.

Examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. Special emphasis is placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. Includes the source, pharmacological and toxicological mechanism of action, detection and identification in body fluids, and treatment of exposure. An overview of protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology, are discussed. In addition, effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered

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Bargaining Power Effects in Financial Contracting : A Joint Analysis of Contract Type and Placement Mode Choices

The aim of this dissertation is to examine bargaining power effects in financial contracting. In particular power effects on firms' choices of contract type (debt vs. equity) and placement mode (public offering vs. private placement)

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Barcelona : urban architecture and community since 2010

Highlights some of the most exciting structures built in Barcelona since 2010, bringing readers on a guided tour of surprising residential buildings, intriguing museums and extraordinary community spaces. The projects, including many additions to existing buildings, are documented with photos, floor plans and texts. Supplementary interviews introduce readers to key players in Barcelona’s architectural scene, while essays shed light on little-known aspects of the city’s urban development and transport planning.

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Banking on (artificial) intelligence : Navigating the realities of ai in financial services

Provides a tailored overview of what AI specifically means for financial services, a highly regulated yet also disrupted industry. it investigates the current state of AI applications in financial services today along with the state of funding and partnerships between tech and banking industries. it also examines the key pillars of responsible AI and the importance of keeping humans in the loop. the book takes a deep dive into the use cases in the financial services industry, the challenges and opportunities, and the fragmented regulatory landscape. how can we effectively assess risks, and balance innovation and customer centricity with trust in AI in financial services? can smaller organizations reap the benefits of the technology? how can institutions deploy AI responsibly and securely, and promote a fairer and more equitable future for more people?

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Bank Investing : A Practitioner's Field Guide

Bank Investing: A Practitioner's Field Guide offers you the essential toolkit to become a successful bank investor. It packages practical lessons, theoretical knowledge, and historical context, all into one compelling and hopefully entertaining book. The book includes conversations with investors and management teams.

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Bank capital and risk-taking : The impact of capital regulation, charter value, and the business cycle

The aim of this study is to contribute to this understanding by answering the following questions: How do banks adjust capital and risk after an increase in capital requirements? How do banks adjust their regulatory capital buffer over the business cycle? And what is the impact of banks' charter value on the regulatory capital buffer?

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Balloon Kyphoplasty

This book focuses on balloon kyphoplasty and alter- tive minimally invasive treatments for stabilization of osteoporotic vertebral fractures. The optimal treatment of a patient with osteoporotic vertebral fractures requires an interdisciplinary - proach, and therefore our book draws on the expertise of orthopedic surgeons, traumatologists and neu- surgeons, and also includes a chapter on medical treatment.

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Ballistic Trauma : A Practical Guide

Ballistic Trauma: A Practical Guide provides a concise guide to the clinical and operational issues surrounding the management of the ballistic casualty. The book crystallizes the knowledge and experience accrued by those dealing with ballistic trauma on a regular basis and extends this to those who have to manage these patients on an occasional basis only.

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Balkan Sprachbund Morpho-Syntactic Features

This book discusses the morpho-syntactic Balkan Sprachbund features in nine languages in which they are most numerous. It contains a wealth of Balkan linguistic material, collected from both the existing literature sources and from the author’s own field work.

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Balancing Exploration and Exploitation by Creating Organizational Think Tanks

Key for successful knowledge management is a balance between exploration and exploitation. Danger arises when exploration is neglected in favour of exploitation since that may result in an organization which lacks innovation capability. In order to prevent this, an idea has been put forward in recent knowledge management research called ambidexterity, which means the simultaneous and balanced pursuing of both exploration and exploitations activities. Tatjana-Xenia Puhan follows up on this idea by concluding that ambidexterity need not necessarily be implemented in one single organization but can also be realised in a network of associated organizations. The interorganizational ambidexterity is based on co-specialisation: one organisation is devoted solely to exploration while associated organizations focus on their competences in exploitation. Furthermore, the author develops the concept of think tanks as organizations that concentrate on radical innovations while their network associates exploit this newly generated knowledge commercially.

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Balanced Website Design : Optimising Aesthetics, Usability and Purpose

Balanced Website Design (BWD) is a new methodology that fuses the strengths of traditional structured, stepped, and iterative approaches with a sharp focus on defining and achieving the desired characteristics of purpose, usability and aesthetics – absolutely essential requirements for any website. The book includes discussions of new perspectives on usability and aesthetics in the special context of website design. BWD is suitable for all types of websites, for individual and/or team projects, and should prove to be of significant value for even the most experienced of website designers. BWD provides guidance, structure and detailed documentation/process support for the activity of designing and implementing your next website – helping you to maximise its effectiveness and relevance.

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Baculovirus : Methods and protocols

Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Bacteriocins : Ecology and Evolution

Microbes produce an extraordinary array of defense systems. These include bacteriocins, a class of antimicrobial molecules with narrow killing spectra, produced by bacteria. The book describes the diversity and ecological role of bacteriocins of Gram-positive and Gram-negative bacteria, presenting a new classification scheme for the former and a state-of-the-art look at the role of bacteriocins in bacterial communication. It discusses the molecular evolution of colicins and colicin-like bacteriocins, and provides a contemporary overview of archaeocins, bacteriocin-like antimicrobials produced by archaebacteria. Furthermore, various modeling (in silico) studies elucidate the role of bacteriocins in microbial community dynamics and fitness, delving into rock-paper-scissors competition and the counter-intuitive survival of the weakest. The book makes compelling reading for a multi-faceted scientific audience, including those working in the fields of biodiversity and biotechnology, notably in the human and animal health domain.

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