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Transgenic and Knockout Models of Neuropsychiatric Disorders
Neuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond.
Toll and Toll-Like Receptors : An Immunologic Perspective
Toll-Like Receptor (TLR) biology would prove to be one of these secrets. Analyses of the evolution of these receptors (Tolls and TLRs) have also helped us to rethink immune system phylogeny. In the first part of this chapter the history of the discovery of Toll and TLR biology is described. The evolution of the TLR genes and theories of immune function are covered in later sections. The remainder of this book presents work from nine groups active in the field. In the first chapter, "The Function of Toll-Like Receptors", Zlatko Dembic sets the stage by introducing us to many of the components of the immune system and their relationships vis a vis Toll receptors. Zlatko finishes his chapter with a discussion about current immune system models and contributes his own 'integrity model'.
Time and Space in Economics
In August 2005, a small but important conference took place at Chuo University in Tokyo, Japan. This international conference, the Chuo Meeting on Economics of Time and Space 2005 (Chuo METS 05), aimed to enrich the respective disciplines of the economics of time (dynamic economics) and the economics of space (spatial economics) and to expand their applicability in the real world. The chapters contained herein are based on the papers presented at that conference. Part I of the book deals with Keynesian macrodynamics, which allows for the existence of involuntary unemployment; Part II focuses on nonlinear dynamics, with an emphasis on the complexity that is generated as a result of the nonlinearity of the system; Part III consists of an empirical analysis of spatial economics through geographical relationships with economic activity; and Part IV analyzes the effects of spatial competition between economic organizations or agents on economic performance in a region.
Therapeutic Lipidology ; 2nd ed.
The chapters focus on recent advances in the field including novel biomarkers and the microbiome, genomics of cardiovascular risks, PCSK9 inhibitors, imaging technologies, and epidemiology of atherosclerotic cardiovascular disease. The book describes new guidelines, novel therapeutic agents, and changes in the understanding of specific lipoproteins and subclasses with regard to their relationships to cardiovascular disease risk. The second edition contains more than thirty chapters covering such topics as the history of lipidology, lipoprotein metabolism and vascular biology, disorders of lipid metabolism, lifestyle/dietary and pharmacologic management for dyslipidemia, the management of dyslipidemia in certain subgroups (e.g., women, children, older patients) and lipid testing, as well as an examination of other biomarkers and testing procedures related to atherosclerosis and cardiovascular disease.
Theory of Random Sets
Theory of Random Sets presents a state of the art treatment of the modern theory, but it does not neglect to recall and build on the foundations laid by Matheron and others, including the vast advances in stochastic geometry, probability theory, set-valued analysis, and statistical inference of the 1990s. The book is entirely self-contained, systematic and exhaustive, with the full proofs that are necessary to gain insight. It shows the various interdisciplinary relationships of random set theory within other parts of mathematics, and at the same time, fixes terminology and notation that are often varying in the current literature to establish it as a natural part of modern probability theory, and to provide a platform for future development.
The World of Rhabdoviruses
In this volume the unique and common features of rhabdoviruses, particularly their morphological, molecular, and pathogenic characteristics, and their phylogenetic relationships are reviewed. Rhabdoviruses have a very wide host range and have been isolated from plants, insects, and almost from all vertebrates including fish and primates. The Rhabdoviridae family consists of six genera which have all been associated with diseases. While rhabdoviruses that are etiological agents of human diseases can cause serious public health problems, other members of this family that infect domestic livestock and agricultural plants can also cause enormous economic loss.
The Soils of Israel
Eleven chapters present a concise description of the soils of Israel, including their distribution, chemical, physical mineralogical characteristics and agricultural attributes. On the background of the various soil-forming factors such as climate, lithology and physiography the pathways of their formation is discussed. Based on the relationships between soils and soil-forming factors, the distribution of the different soil types is explained. An ample bibliography backs up this exposition, supplemented by numerous figures, tables, colour plates and maps. The description of the contemporaneous surface soils is supplemented by a review of the numerous paleosols with their paleogeographic significance.
The Social Side of Mergers and Acquisitions : Cooperation relationships after mergers and acquisitions
Florian Frensch investigates which individual characteristics of employees and which dyadic factors of relationship partners affect the cooperation between employees of previously separated firms. The author develops an innovative approach for gathering network data with the help of a dynamic computer-based questionnaire which allows him to conduct a full network analysis of a group of approximately 400 employees on the lower operative level of the firms. He shows that structural cooperation requirements and integration measures are powerful means to make employees cooperate after M&A and provides answers to the questions how integration after M&A can be measured, explained and improved.
The Self-Marginalization of Wilhelm Stekel : Freudian Circles Inside and Out
As both an early disciple of and influence on Freud, Wilhelm Stekel enjoyed a unique position within the analytic movement. More recently, he has been notable more for his ostracism from Freud’s sphere and little else. The Self-Marginalization of Wilhelm Stekel brings a fresh perspective on Stekel, revealing the complex, symbiotic bond between mentor and follower in its many social, interpersonal, and psychological forms.In addition to shedding light on a famous outsider, this biography is set in a dual context of the formative years of psychoanalysis and Freud’s relationships with his colleagues: comparisons and contrasts abound with Adler, Jung, and other, revered exiles from Freudian circles. At the same time, each chapter defines and identifies a particular aspect of the marginalization process, including self-marginalization, the relationship of marginals to the mainstream, and the value of marginalization in the construction of identity.
The Pendulum : Scientific, Historical, Philosophical and Educational Perspectives
The pendulum is a universal topic in primary and secondary schools, but its full potential for learning about physics, the nature of science, and the relationships between science, mathematics, technology, society and culture is seldom realised.Contributions to this 32-chapter anthology deal with the science, history, methodology and pedagogy of pendulum motion. There is ample material for the richer and more cross-disciplinary treatment of the pendulum from elementary school, to high school, and through to advanced university classes.
The Invisible Hand : Economic Thought Yesterday and Today
The economies of the European Union are today highly integrated. Constitutive part of this high degree of integration is the euro which unites most of the Member States within thee uro-zone. In order to ensure prosperity and stabilityofthis Union in the spirit of the European Stability and Growth Pact, economic policies in both the Union and its Member States need to be monitored and co-ordinated appropriately. This applies in particular also because of the enlargement process which adds a further dimension to the continuous challenge of having to deal with different economic policy concepts and traditions in our Union. Understanding the economic and sociopolitical debates in the individual Member States of the Union and elsewhere requires a solid knowledge not only of the economic but also of the social and historical background of these debates. In economics, more than in the natural sciences, human norms and conflicts play a central role in addition to logical relationships and empirical findings. Therefore, looking only at economic formulae and empirical facts will not be enough. Most economic textbooks, especially from the Anglo-Saxon area, tend to c- centrate more on the technically correct and often model-based presentation of their subject-matter than on its socio-political background. However, in view of the significance of economic reality for every citizen in Europe, it is also important to reach those who have not obtained a university degree in economics.
The European Labour Market : Regional Dimensions
Brings together up-to-date findings on the regional dimensions of European labour markets. It provides a conceptual and empirical study of the interactions between the European economy and its regions, paying particular attention to the issue of the transition of Central and Eastern European countries to a market economy. The topics analysed include: the structure of the shocks affecting employment (regional, industrial, national), the relationships between labour market efficiency and the regional distribution of unemployment, wage flexibility in EU member countries or in their regions and the role of active labour market policies in affecting the regional distribution of employment and unemployment.
The Econometrics of Panel Data : Fundamentals and Recent Developments in Theory and Practice
Provides a general overview of the econometrics of panel data, both from a theoretical and from an applied viewpoint. Since the pioneering papers by Kuh, Mundlak, Hoch and Balestra and Nerlove, the pooling of cross section and time series data has become an increasingly popular way of quantifying economic relationships. Each series provides information lacking in the other, so a combination of both leads to more accurate and reliable results than would be achievable by one type of series alone. This third, enhanced edition provides a complete and up to date presentation of theoretical developments as well as surveys about how econometric tools are used to study firms and household’s behaviors. It contains eleven entirely new chapters while the others have been largely revised to account for recent developments in the field.
The Andes : Active Subduction Orogeny
Convergent plate margins and subduction zones are first order features shaping the Earth. Convergent continental margins combine the majority of processes that affect the internal architecture thermal and geochemical character of continental lith- phere. In addition, the close relationships between active deformation and uplift, m- matism and associated crustal growth, ore formation, the release of more than 90% of global seismic energy at convergent margins, make these plate boundaries imp- tant natural laboratories where mass and energy flux rates can be studied at various scales. Since the advent of plate tectonic theory, it has been recognized that all of these phenomena are intimately related and often governed by feedback mechanisms. Accordingly, subduction orogeny has become an international, high-priority theme in process-oriented, earth-system analysis.
Teaching Tolerance in a Globalized World
Identifies factors and conditions that can help schools and education systems promote tolerance in a globalized world. The IEA’s International Civic and Citizenship Study (ICCS) is a comparative research program designed to investigate the ways in which young people are prepared to undertake their roles as citizens, and provides a wealth of data permitting not only comparison between countries but also comparisons between schools within countries, and students within countries. Advanced analytical methods provide insights into relationships between students’ attitudes towards cultural diversity and the characteristics of the students themselves, their families, their teachers and school principals. The rich diversity of educational and cultural contexts in the 38 countries who participated in ICCS 2009 are also acknowledged and addressed.
Teacher Quality, Instructional Quality and Student Outcomes : Relationships Across Countries, Cohorts and Time
This volume offers insights from modeling relations between teacher quality, instructional quality and student outcomes in mathematics across countries. The relations explored take the educational context, such as school climate, into account. The International Association for the Evaluation of Educational Achievement’s Trends in Mathematics and Science Study (TIMSS) is the only international large-scale study possessing a design framework that enables investigation of relations between teachers, their teaching, and student outcomes in mathematics. TIMSS provides both student achievement data and contextual background data from schools, teachers, students and parents, for over 60 countries.
Teacher Learning and Development : The Mirror Maze
This book synthesises current practice and research developments from internationally recognised scholars and practitioners, to provide theoretical and practical knowledge which informs teacher education, development and professional learning. Sections in the book include: the role and significance of learning relationships; emerging dilemmas and challenges; and processes of self-study in teacher education. Throughout the book, self-study contributions highlight the complexity, challenges, struggles, solutions and successes in teacher education experience. They foreshadow exciting developments for further research. Accordingly, the book is likely to appeal to a wide audience of educators – including education academics, teachers, student teachers and researchers.
Synthesis, Properties and Applications of Ultrananocrystalline Diamond ; Proceedings of the NATO ARW on Synthesis, Properties and Applications of Ultrananocrystalline Diamond, St. Petersburg, Russia, from 7 to 10 June 2004.
There are two forms of UNCD, dispersed particles and films. The two communities of researchers working on these two forms of UNCD have hitherto lacked a common forum in which to explore areas of scientific and technological overlap. As a consequence, the two fields have up to now developed independently of each other. The time had clearly come to remedy this situation in order to be able to take full advantage of the enormous potential for societal benefits to be derived from exploiting the synergistic relationships between UNCD dispersed particulates and UNCD films. The NATO sponsored ARW therefore occurred in a very timely manner and was successful in beginning the desired dialogue, a precondition for making progress toward the above stated goal. The discovery of UNCD completes a triadof nanostructured carbonswhich includes fullerenes and nanotubes.
Symbiotic interaction ; 5th International workshop, Symbiotic 2016, Padua, Italy, September 29–30, 2016, revised selected papers
The 12 full papers and 3 short papers presented in this volume were carefully reviewed and selected from 23 submissions. The idea of symbiotic systems put forward in this workshop capitalizes on the computers’ ability to implicitly detect the users goals, preferences or/and psycho-physiological states and thereby enhancing human-computer interaction (HCI). The papers present an overview of the symbiotic relationships between humans and computers with emphasis on user-driven research on symbiotic systems, adaptive systems, implicit input data, physiological computing and BCI, but also on understanding the nature of the interdependence and agency between computers and humans more broadly.
Symbiotic association of microorganisms with medicinal and herbal plants
Research establishes that symbiotic association of microbes with medicinal and herbal plants enhance the growth and accumulation of bioactive materials, and that species of microbes including bacterial and fungal species play a key role.
