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Brain tumor pathology : Current diagnostic hotspots and pitfalls
Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.
Biostatistica in radiologia : Progettare, realizzare e scrivere un lavoro scientifico radiologico = Biostatistics in Radiology: Designing, creating and writing a radiological scientific work
The progressive affirmation of evidence-based medicine requires radiology to make a qualitative leap: from demonstrating the ability to see more and better to demonstrating a significant improvement in the health or quality of life of patients.
Basic concepts in medicinal chemistry
Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. Specific sections of the text have been updated to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills.
Automated machine learning : Methods, systems, challenges
This book presents the first comprehensive overview of general methods in Automated Machine Learning (AutoML), collects descriptions of existing systems based on these methods, and discusses the first series of international challenges of AutoML systems. The recent success of commercial ML applications and the rapid growth of the field has created a high demand for off-the-shelf ML methods that can be used easily and without expert knowledge. However, many of the recent machine learning successes crucially rely on human experts, who manually select appropriate ML architectures (deep learning architectures or more traditional ML workflows) and their hyperparameters. To overcome this problem, the field of AutoML targets a progressive automation of machine learning, based on principles from optimization and machine learning itself.
Antidiabetic medicinal plants and herbal treatments
Diabetes is a chronic condition associated with metabolic disorder. Persons suffering from diabetes have shown accelerated levels of blood sugar which often harms the heart, blood vessels, eyes, kidneys, and nerves. Over the past few decades, the prevalence of diabetes has been progressively increasing. Synthetic drugs are used to treat diabetic patients to help control the disorder, but it is shown that numerous medicinal plants and herbal drugs are widely used in several traditional systems of medicine to prevent and treat diabetes. They are reported to produce beneficial effects in combating diabetes and alleviating diabetes-related complications. These plants contain phtyonutrients and phytoconstituents demonstrating protective or disease preventive properties. In many developing countries, herbal drugs are recommended by traditional practitioners for diabetes treatment because the use of synthetic drugs is not affordable.
Anaesthesia, pain, intensive care and emergency medicine - A.P.I.C.E. ; Proceedings of the 20th Postgraduate Course in Critical Care Medicine, Trieste, Italy - November 18-21, 2005
The main objective of modern medicine has been the acquisition of increased skills and highly specialised knowledge in the various disciplines. At the same time, there has been a progressive multidisciplinary and multi-professional interest in acute disease conditions that place the patient in potential or real life-threatening situations. The state of the art of intensive medicine comprises a wide range of sophisticated interventions and collaboration between different medical disciplines, both of which give the patient access to the most advanced forms of treatment that are currently available.
Alzheimer’s and new horizon
Alzheimer's disease (AD) is characterized by progressive loss of memory and other cognitive functions. This study aims to discuss Alzheimer's disease (AD) and its increasing incidence and related huge fund to take care of such patients and will understand the pathophysiology in order to successfully fight this enigmatic illness and the goal of is the treatment for individuals with AD. Our study will also focus on the mutualistic relationship between AD and SARS- COV-2 infection and its correlation with cancer will be also discussed...
Algèbre, Chapitres 1 à 3 = Algebra, Chapters 1 to 3
To do algebra is essentially to calculate, that is to say to perform, on elements of a set, (<algebraic operations n, the best-known example of which is provided by the (<four rules)) of elementary arithmetic. This is not the place to retrace the slow process of progressive abstraction by which the notion of algebraic operation, initially restricted to natural integers and to measurable quantities, gradually widened its field, as it grew. at the same time generalized the notion of ((number O, until, going beyond the latter, it came to apply to elements which no longer had any character ((numeric)>, for example to permutations of a - seems (see Historical Note in chap. 1).
AJCC Cancer Staging Atlas : AJCC Cancer Staging Illustrations in PowerPoint® From the AJCC Cancer Staging Atlas
The AJCC Cancer Staging Atlas contains black-and-white illustrations, created exclusively for the book, depicting the anatomic extent of disease for tumor (T), regional lymph node (N), and distant metastasis (M). The images provide thorough anatomic depictions to clarify critical structures and allow the reader to instantly visualize the progressive extent of malignant disease. Numerous labels identify important anatomic structures.
AJCC Atlante per la stadiazione dei tumori maligni = Atlas for the Staging of Malignant Tumors
he atlas contains over 400 specially created black and white illustrations describing the anatomical extent of the malignant tumor in the primary site (T), regional lymph nodes (N) and distant metastases (M) for various sites, including the head and neck area, the digestive system, the thorax, the musculoskeletal system, the soft tissues, the breast, the urinary system and the genital system. Each illustration provides precise and detailed descriptions designed to clarify the crucial anatomical structures and to provide the reader with an immediate view of the progressive extension of the disease. The most important anatomical structures are identified by specific definitions.
AI and law : How automation is changing the law
Provides insights into how AI is changing legal practice, government processes, and individuals’ access to those processes, encouraging each of us to consider how technological advances are changing the legal system. Particularly, and distinct from current debates on how to regulate AI, this books focuses on how the progressive merger between computational methods and legal rules changes the very structure and application of the law itself.
Aging and Senescence
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. Although recent developments in molecular biology are far from understanding the biological basis of aging, research suggests that targeting the aging process itself could ameliorate many age-related pathologies.
Advanced memory optimization techniques for low-power embedded processors
this book explores a collaborative approach by proposing novel memory hierarchies and software optimization techniques for the optimal utilization of these memory hierarchies. Linking memory architecture design with memory-architecture aware compilation results in fast, energy-efficient and timing predictable memory accesses.The evaluation of the optimization techniques using real-life benchmarks for a single processor system, a multiprocessor system-on-chip (SoC) and for a digital signal processor system, reports significant reductions in the energy consumption and performance improvement of these systems. The book presents a wide range of optimizations, progressively increasing in the complexity of analysis and of memory hierarchies. The final chapter covers optimization techniques for applications consisting of multiple processes found in most modern embedded devices.
A Fair Share of Tax : A Fiscal Anthropology of Contemporary Sweden
Takes a taxpayer's perspective to the relations taxation creates between people and their state. Larsen proposes that in order to understand tax compliance and cheating, we have to look beyond law, psychological experiments and surveys to include tax collectors and taxpayers' practices. The text explores the view of taxes seen as citizen’s explicit economic relation to the state and implicit economic relation to all other compatriots. Larsen suggests how to build and increase tax compliance if we take the idea of taxation creating reciprocal relations seriously.
