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Nutraceuticals : Sources, processing methods, properties, and applications

Explores the impact of nutraceutical compounds on human health and their main pharmacological contributions. Organized into three parts, this book addresses nutraceutical production, applications for disease prevention and treatment, and current trends, especially the role of nutraceuticals in cosmeceutical. Nutraceuticals are a class of products that can help people improve their health, reduce the risk of disease, extend their lives, and control the structure and functioning of their bodies. However, due to multiple hurdles that prevent nutraceuticals from circulating in an active form in the body, their use is associated with diminished therapeutic efficacy. Recognizing this problem, the book explores the root of the nutraceutical delivery system and its codelivery methods with a focus on medicines. With contributions from experienced nutraceutical experts, this book serves as a valuable reference for nutrition researchers, food scientists, pharmacologists, and those who are researching and studying in related areas.

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Numerical Techniques for Chemical and Biological Engineers Using MATLAB® : A Simple Bifurcation Approach

This book addresses the bifurcation characteristics of chemical and biological processes as the general case and treats systems with a unique steady state as special cases. It uses a system approach which is the most efficient for knowledge organization and transfer. The book develops mathematical models for many commercial processes utilizing the mass-, momentum-, and heat-balance equations coupled to the rates of the processes that take place within the boundaries of the system. The models are solved numerically through MATLAB codes with emphasis on the design and optimization of the chemical and biological industrial equipment and plants.

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Numerical solution of Variational Inequalities by Adaptive Finite Elements

Franz-Theo Suttmeier describes a general approach to a posteriori error estimation and adaptive mesh design for finite element models where the solution is subjected to inequality constraints. This is an extension to variational inequalities of the so-called Dual-Weighted-Residual method (DWR method) which is based on a variational formulation of the problem and uses global duality arguments for deriving weighted a posteriori error estimates with respect to arbitrary functionals of the error. In these estimates local residuals of the computed solution are multiplied by sensitivity factors which are obtained from a numerically computed dual solution. The resulting local error indicators are used in a feed-back process for generating economical meshes which are tailored according to the particular goal of the computation.

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Numerical Solution of Partial Differential Equations on Parallel Computers

The scientific fields of Ma- ematics and Physics provide a powerful vehicle for such descriptions in terms of Partial Differential Equations (PDEs). Formulated as such equations, physical laws can become subject to computational and analytical studies. In the computational setting, the equations can be discreti ed for ef?cient solution on a computer, leading to valuable tools for simulation of natural and man-made processes. Numerical so- tion of PDE-based mathematical models has been an important research topic over centuries, and will remain so for centuries to come. In the context of computer-based simulations, the quality of the computed results is directly connected to the model’s complexity and the number of data points used for the computations. Therefore, computational scientists tend to ?ll even the largest and most powerful computers they can get access to, either by increasing the si e of the data sets, or by introducing new model terms that make the simulations more realistic, or a combination of both. Today, many important simulation problems can not be solved by one single computer, but calls for parallel computing.

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Numerical Simulation of Mechatronic Sensors and Actuators

The second edition of this book fully preserves the character of the first edition to combine the detailed physical modeling of mechatronic systems and their precise numerical simulation using the Finite Element (FE) method. Most of the text and general appearance of the previous edition were retained, while the coverage was extended and the presentation improved. A large part of the book describes the application of the developed numerical calculation schemes to industrial problems, e.g.: analysis and optimization of electrodynamic loudspeakers. In these parts, new computational methods are included, and last but not least, this new edition contains a new chapter on computational aeroacoustics to study the complex phenomenon of flow induced noise.

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Numerical Simulation in Molecular Dynamics : Numerics, Algorithms, Parallelization, Applications

Particle models play an important role in many applications in physics, chemistry and biology. They can be studied on the computer with the help of molecular dynamics simulations. This book presents in detail both the necessary numerical methods and techniques (linked-cell method, SPME-method, tree codes, multipole technique) and the theoretical background and foundations. It illustrates the aspects modelling, discretization, algorithms and their parallel implementation with MPI on computer systems with distributed memory. Furthermore, detailed explanations are given to the different steps of numerical simulation, and code examples are provided.

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Numerical Methods Using Java : For Data Science, Analysis, and Engineering

Covers a wide range of topics, including chapters on linear algebra, root finding, curve fitting, differentiation and integration, solving differential equations, random numbers and simulation, a whole suite of unconstrained and constrained optimization algorithms, statistics, regression and time series analysis. The mathematical concepts behind the algorithms are clearly explained, with plenty of code examples and illustrations to help even beginners get started. You will: Program in Java using a high-performance numerical library / Learn the mathematics for a wide range of numerical computing algorithms / Convert ideas and equations into code / Put together algorithms/ and classes to build your own engineering solution / Build solvers for industrial optimization problems / Do data analysis using basic and advanced statistics

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Numerical Methods for Nonsmooth Dynamical Systems : Applications in Mechanics and Electronics

This book concerns the numerical simulation of dynamical systems whose trajectories may not be differentiable everywhere. They are named nonsmooth dynamical systems. They make an important class of systems, firstly because of the many applications in which nonsmooth models are useful, secondly because they give rise to new problems in various fields of science. Usually nonsmooth dynamical systems are represented as differential inclusions, complementarity systems, evolution variational inequalities, each of these classes being itself split into several subclasses.

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Numerical Mathematics and Advanced Applications ENUMATH 2019 ; European Conference, Egmond aan Zee, The Netherlands, September 30 - October 4

It contians basic aspects and new trends in numerical mathematics and scientific and industrial applications, all examined at the highest level of international expertise.

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Numerical Mathematics and Advanced Applications ; Proceedings of ENUMATH 2007, the 7th European Conference on Numerical Mathematics and Advanced Applications, Graz, Austria, September 2007

The European Conference on Numerical Mathematics and Advanced Applications (ENUMATH) is a series of meetings held every two years to provide a forum for discussion on recent aspects of numerical mathematics and their applications. These proceedings contain a selection of invited plenary lectures, papers presented in minisymposia and contributed papers. Topics include theoretical aspects of new numerical techniques and algorithms as well as of applications in engineering and science. The book will be useful for a wide range of readers, giving them an excellent overview of the most modern methods, techniques, algorithms and results in numerical mathematics, scientific computing and their applications.

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Numerical Mathematics and Advanced Applications ; Proceedings of ENUMATH 2005 the 6th European Conference on Numerical Mathematics and Advanced Applications, Santiago de Compostela, Spain, July 2005

This book include applications such as atmosphere and ocean, water pollution, electromagnetism, interface problems, waves, finance, heat transfer, unbounded domains, numerical linear algebra, convection-diffusion, fluid-structure, plates, solids, hyperbolic equations, multiphase flow, Navier-Stokes, singular perturbation problems, non linear PDE, control, parabolic equations, as well as methodologies such as a posteriori error estimates, discontinuous Galerkin methods, multiscale methods, optimization, adaptive methods, domain decomposition techniques, exponential integrators, hp-finite elements, level set methods, fractional step methods, penalty procedures, and finite volumes. The book gives an extensive overview of the most recent research in scientific computing, providing to the reader the latest developments concerning the mathematical issues and the applications of this active field of science.

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Numerical computation, data analysis and software in mathematics and engineering

Include the aspects of the meshless method, numerical simulation, mathematical models, deep learning and data analysis. Meshless methods, such as the improved element-free Galerkin method, the dimension-splitting, interpolating, moving, least-squares method, the dimension-splitting, generalized, interpolating, element-free Galerkin method and the improved interpolating, complex variable, element-free Galerkin method, are presented. Some complicated problems, such as tge cold roll-forming process, ceramsite compound insulation block, crack propagation and heavy-haul railway tunnel with defects, are numerically analyzed.

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Numerical Approximation Methods for Elliptic Boundary Value Problems : Finite and Boundary Elements

Although the aim of this book is to give a unified introduction into finite and boundary element methods, the main focus is on the numerical analysis of boundary integral and boundary element methods. Starting from the variational formulation of elliptic boundary value problems boundary integral operators and associated boundary integral equations are introduced and analyzed. By using finite and boundary elements corresponding numerical approximation schemes are considered.

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Numerical Analysis and Its Applications ; 3rd International Conference, NAA 2004, Rousse, Bulgaria, June 29 - July 3, 2004, Revised Selected Papers

Constitutes the refereed post-proceedings of the Third International Conference on Numerical Analysis and Its Applications, held in Bulgaria in June/July 2004. This book addresses various aspects of numerical analysis. It covers the application fields such as computational sciences and engineering, chemistry, physics, economics, and simulation.

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Nuel Belnap on Indeterminism and Free Action

Seeks to further the use of formal methods in clarifying one of the central problems of philosophy: that of our free human agency and its place in our indeterministic world. It celebrates the important contributions made in this area by Nuel Belnap, American logician and philosopher. Philosophically, indeterminism and free action can seem far apart, but in Belnap’s work, they are intimately linked. This book explores their philosophical interconnectedness through a selection of original research papers that build forth on Belnap’s logical and philosophical work. Some contributions take the form of critical discussions of Belnap's published work, some develop points made in his publications in new directions, and others provide additional insights on the topics of indeterminism and free action.

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NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders : from Genes to Therapeutics

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.

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Novepernove : Sudoku : segreti e strategie di gioco = Novepernove : Sudoku : game secrets and strategies

The game of Sudoku has exploded in the Western world since 2005 and has since continued to expand, to gather new followers, to proliferate specialized magazines on newsstands and dedicated sites on the Internet. Sudoku success shows no signs of slowing down. All the major newspapers offer daily some patterns to be solved; associations and federations were born; local tournaments, various national championships and even an annual world championship are organized; the proposals for variants of the classic Sudoku multiply; many university professors have launched graduate theses on the subject; various software products have been written on PCs, on dedicated hardware and on the main interactive game consoles.

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Novel Trends in Brain Science : Brain Imaging, Learning and Memory, Stress and Fear, and Pain

With the development of neural science, knowledge of the molecules and neurons that comprise the brain has increased exponentially in the past two decades. In Novel Trends in Brain Science, leading neuroscientists from Japan and Taiwan describe the latest and most relevant research in brain science, including state-of-the-art brain-imaging technologies such as fMRI, MR-DTI, TMS, and MEG, and also discuss learning, memory, emotions, and pain. With a wide range of contributors, the book presents valuable insights into functional neuroimaging, white matter tractography, synaptic plasticity, emoti.

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Novel Optical Resolution Technologies

After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capable of resolving the surface as wellas the insid estructure of crystalsat the atomiclevel while newhigh-performance computing resourcesafford thecapability of modeling the complexlarge-scale alignments necessary to simulatecrystallizationinrealsystems. Asaresult, the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process.The vastpotential ofcrystallizationasan- portant feld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century.

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Novel mouse model for future autism research

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.

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