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Multiple Testing Procedures and Applications to Genomics
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments.
Multimedia Retrieval
The single chapters of this textbook explain the general architecture of multimedia information retrieval systems; various metadata languages like Dublin Core, RDF, or MPEG; pattern recognition through Markov models, unsupervised learning, and pattern clustering; various indexing approaches to audio and video streams; interaction and control; the protection of content and user privacy; and search effectiveness and efficiency.
Multimedia Content Representation, Classification and Security ; International Workshop, MRCS 2006, Istanbul, Turkey, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the International Workshop on Multimedia Content Representation, Classification and Security, MRCS 2006, held in Istanbul, Turkey in September 2006. The 100 revised papers presented together with 4 invited lectures were carefully reviewed and selected from more than 190 submissions. The papers are organized in topical sections on biometric recognition, multimedia content security, steganography, watermarking, authentication, classification for biometric recognition, digital watermarking, content analysis and representation, 3D object retrieval and classification, representation, analysis and retrieval in cultural heritage, content representation, indexing and retrieval, content analysis and classification, feature extraction and classification, multimodal signal processing, 3D video and free viewpoint video, multimedia content transmission and classification, video and image processing, as well as video analysis and representation.
Multilingualism, Cultural Identity, and Education in Morocco
This book is an original contribution to the field of multilingualism and cultural identity. It investigates the ramifications of multilingualism for language choice patterns and attitudes among Moroccans. It focuses on the impact of multilingualism on cultural identity and education. It includes a debate on education and language planning policies in Morocco since independence. It reveals the complexity of post-colonial Morocco characterized by contradictory attitudes toward the languages in contact and toward language policy and education. It is of interest to students and researchers of sociolinguistics, cultural studies, anthropology and gender studies as well as for specialists of education and language policy/planning.
Multilevel Block Factorization Preconditioners : Matrix-based Analysis and Algorithms for Solving Finite Element Equations
This monograph is the first to provide a comprehensive, self-contained and rigorous presentation of some of the most powerful preconditioning methods for solving finite element equations in a common block-matrix factorization framework. Topics covered include the classical incomplete block-factorization preconditioners and the most efficient methods such as the multigrid, algebraic multigrid, and domain decomposition. Additionally, the author discusses preconditioning of saddle-point, nonsymmetric and indefinite problems, as well as preconditioning of certain nonlinear and quadratic constrained minimization problems that typically arise in contact mechanics. The book presents analytical as well as algorithmic aspects.
Multi-Agent Systems and Applications V ; 5th International Central and Eastern European Conference on Multi-Agent Systems, CEEMAS 2007, Leipzig, Germany, September 25-27, 2007, Proceedings
The technical research paper section of the proceedingscontains pure - search papers as well as research results in application settings. The goal is to demonstrate the real-life value and commercial reality of multi-agent systems as well as to foster the communication between academia and industry in this eld.
Multiagent System Technologies ; 6th German Conference, MATES 2008, Kaiserslautern, Germany, September 23-26, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th German Conference on Multiagent Systems Technologies, MATES 2008, held in Kaiserslautern, Germany, in September 2008 - co-located with the 31st German Conference on Artificial Intelligence, KI 2008.The 16 revised full papers presented together with 2 invited talks were carefully reviewed and selected from 35 submissions. The papers present and discuss the latest advances of research and development in the area of autonomous agents and multiagent systems ranging from theoretical and methodological issues to applications in various fields.
Morphosemantic Number : From Kiowa Noun Classes To UG Number Features
This volume presents: the foundations of a unified morphosemantic theory of number; insight into the flow of information from the lexicon, via syntax, into the morphology; wide-ranging topics: nominal semantics, noun classes, DP syntax, agreement, suppletion, complex morphology.
Morphology, Molecules, Evolution and Phylogeny in Polychaeta and Related Taxa; Proceedings of two ISSI Workshops, 18–22 October 1999 and 15–19 May 2000, Bern, Switzerland
Recently, evidence has been accumulated which shows that some of the groups formerly regarded as independent "phyla" such as Pogonophora (now recognized as Siboglinidae), Echiura, Myzostomida and perhaps Sipuncula, are most probably nothing else than greatly modified Annelida. The extreme morphological diversity found especially in Polychaeta displays the plasticity of a simple segmented organisation that basically is nothing else but a serial repetition of identical units. Thus, annelids are highly important to our understanding of fundamental questions about morphological and adaptive diversity, as well as clarifying evolutionary changes and phylogenetic relationships. The book aims to summarize our knowledge on Polychaetes polychaetes and their allies and gives an overview of recent advances gained by studies that employed conventional and modern methods plus, increasingly and importantly, the use of molecular markers and computer-assisted kinship analyses. It also reflects the state of art in polychaete sciences and presents new questions and controversies. As such it will significantly influence the direction of research on Polychaeta and their related taxa.
Monetary Policy and Macroeconomic Stabilization in Latin America
Latin America is a very important region of the globe, which has been buffeted by successive waves of economic instability within the last decades. These waves have caused several episodes of hyperinflation or near hyperinflation, and several currency and financial crises, which, in certain moments, have even spilled over and affected other emerging markets. This has resulted in huge costs in terms of lost potential growth, and, as is inevitable, the markets most affected by this have been the least capable of defending themselves. In a region plagued by still considerable rates of social exclusion, with some of the highest rates of income concentration in the whole globe, the human costs of these crises have been very substantial. Starting in the early 1990s, the slow implementation of reforms, plus the resumption of more sustained growth—to a substantial degree linked to the increase in commodity prices, especially since the early 2000s—seems to have resulted in a more stable situation. Initially, in early reformers like Chile, later in the larger economies of the region, like Brazil and Mexico, a consensus— embraced by both sides of the political spectrum—towards integration in global markets, both in their trade and financial components, floating exchange rates, independent monetary authorities, and sustainable fiscal policies has emerged.
Molecular Basis of Symbiosis
Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly significant. In symbiotic associations, co-evolution of the partner organisms has led to specific mechanisms of signal exchange and reciprocal regulation, and resulted in novel physiological capabilities of the association as compared to those of the individual partners. Symbiosis research has recently entered an exciting era because molecular biology techniques are available for studying partner organisms in association and in a culture-independent manner. It is the goal of this book to contribute towards a broader perspective and an understanding of the function of symbiotic systems. 14 different model systems have been chosen, comprising well known symbioses as well as novel experimental systems which have only recently become amenable to experimental manipulation.
Molecular analysis of B lymphocyte development and activation
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
Modern Mathematical Statistics with Applications
This book tries to strike a balance between mathematical foundations and statistical practice. The book provides a clear and current exposition of statistical concepts and methodology, including many examples and exercises based on real data gleaned from publicly available sources. The main focus of the book is on presenting and illustrating methods of inferential statistics used by investigators in a wide variety of disciplines, from actuarial science all the way to zoology. It begins with a chapter on descriptive statistics that immediately exposes the reader to the analysis of real data. The next six chapters develop the probability material that facilitates the transition from simply describing data to drawing formal conclusions based on inferential methodology. Point estimation, the use of statistical intervals, and hypothesis testing are the topics of the first three inferential chapters. The remainder of the book explores the use of these methods in a variety of more complex settings.
Modern Food Microbiology
With 30 revised and updated chapters, the new edition of this classic text brings benefits to professors and students alike who will find new sections on proteobacteria, bottled water, food sanitizers (eletrolyzed oxidating water, ozone, chlorine, activin, chitosans, endolysins, etc.), bicontrol, biosensors quorum sensing, molecular genetic methods of analysis, food safety objectives, noroviruses, and prions. The book builds on the trusted and established sections on food preservation by modified atmosphere, high pressure and pulsed electric field processing, food-borne pathogens, food regulations, fresh-cut produce, new food products, and risk assessment and analysis. In-depth references, appendixes, illustrations, index and thorough updating of taxonomies make this an essential for every food scientist.
Modeling and Using Context ; 5th International and Interdisciplinary Conference, CONTEXT 2005, Paris, France, July 5-8, 2005, Proceedings
Context is of crucial importance for research and applications in many disciplines, as evidenced by many workshops, symposia, seminars, and conferences on specific aspects of context. The International and Interdisciplinary Conference on Modeling and Using Context (CONTEXT), the oldest conference series focusing on context, provides a unique interdisciplinary emphasis, bringing together participants from a wide range of disciplines, including artificial intelligence, cognitive science, computer science, linguistics, organizational science, philosophy, psychology, ubiquitous computing, and application areas such as medicine and law, to discuss and report on context-related research and projects. Previous CONTEXT conferences were held in Rio de Janeiro, Brazil (1997), Trento, Italy (1999, LNCS 1688), Dundee, UK (2001, LNCS 2116), and Palo Alto, USA (2003, LNCS 2680). CONTEXT 2005 was held in Paris, France during July 5–8, 2005. There was a strong response to the CONTEXT 2005 Call for Papers, with 120 submissions received. A careful review process assessed all submissions, with each paper first reviewed by the international Program Committee, and then reviewer discussions were initiated as needed to assure that the final decisions carefully considered all aspects of each paper. Reviews of submissions by the Program Chairs were supervised independently and anonymously, to assure fair consideration of all work. Out of the 120 submissions, 23 were selected as full papers for oral presentation, and 20 were selected as full papers for poster presentation. These outstanding papers are presented in this proceedings.
Model Based Inference in the Life Sciences : A Primer on Evidence
The abstract concept of "information" can be quantified and this has led to many important advances in the analysis of data in the empirical sciences. This text focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The fundamental science question relates to the empirical evidence for hypotheses in this set—a formal strength of evidence. Kullback-Leibler information is the information lost when a model is used to approximate full reality. Hirotugu Akaike found a link between K-L information (a cornerstone of information theory) and the maximized log-likelihood (a cornerstone of mathematical statistics). This combination has become the basis for a new paradigm in model based inference. The text advocates formal inference from all the hypotheses/models in the a priori set—multimodel inference.
Mobile response ; 1st International Workshop on mobile information technology, for emergency response, mobile response 2007, Sankt Augustin, Germany, February 22-23, 2007. Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the First International Workshop on Mobile Information Technology for Emergency Response, MobileResponse 2007 held in Sankt Augustin, Germany in February 2007.
Mixture Formation in Internal Combustion Engines
This book covers the various approaches to modelling and optimising the spray and mixture formation processes in modern internal combustion engines. Due to their complexity and importance in predicting the temporal and spatial distribution of liquid and gaseous fuel inside the cylinder, special emphasis is put on the detailed description of multi-dimensional CFD-models. The book describes and discusses the most widely used mathematical models for in-cylinder spray and mixture formation processes.
Mixed Finite Elements, Compatibility Conditions, and Applications : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy June 26–July 1, 2006
Since the early 70's, mixed finite elements have been the object of a wide and deep study by the mathematical and engineering communities. The fundamental role of this method for many application fields has been worldwide recognized and its use has been introduced in several commercial codes. An important feature of mixed finite elements is the interplay between theory and application. Discretization spaces for mixed schemes require suitable compatibilities, so that simple minded approximations generally do not work and the design of appropriate stabilizations gives rise to challenging mathematical problems.
Microstructuring of Glasses
As microstructured glass becomes increasingly important for microsystems technology, the main application fields include micro-fluidic systems, micro-analysis systems, sensors, micro-actuators and implants. And, because glass has quite distinct properties from silicon, PMMA and metals, applications exist where only glass devices meet the requirements. The main advantages of glass derive from its amorphous nature, the precondition for its - theoretically - direction-independent geometric structurability. Microstructuring of Glasses deals with the amorphous state, various glass compositions and their properties, the interactions between glasses and the electromagnetic waves used to modify it.
