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NF-kB/Rel Transcription Factor Family
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
New Results in Numerical and Experimental Fluid Mechanics VI ; Contributions to the 15th STAB/DGLR Symposium Darmstadt, Germany, 2006
The volume gives a broad overview over the ongoing work in this field in Germany, with the topics being high-aspect ratio wings, low aspect-ratio wings, bluff bodies, laminar flow control and transition, active flow control, hypersonic flows, aeroelasticity, aeroacoustics, mathematical fundamentals/ numerical simulation, physical fundamentals, and facilities.
New Results in Numerical and Experimental Fluid Mechanics V ; Contributions to the 14th STAB/DGLR Symposium Bremen, Germany 2004
This volume contains the contributions to the 14. Symposium of the STAB (German Aerospace Aerodynamics Association). The volume gives a broad overview over the ongoing work in this field in Germany, with the topics being high-aspect ratio wings, low aspect-ratio wings, bluff bodies, laminar flow control and transition, active flow control, hypersonic flows, aeroelasticity, aeroacoustics, mathematical fundamentals/ numerical simulation, physical fundamentals, and facilities.
New Frontiers in Regenerative Medicine
Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. Areas of focus include the nervous system and hippocampal neurogenesis, along with the functional significance of pro-inflammatory cytokines, and the production of free radicals after brain ischemia; the digestive and integumentary systems, dealing with hepatocyte transplantation, pancreatic regeneration, and skin and hair regeneration; and the cardiovascular system, with repair and remodeling of the lung and heart, and arterial remodeling with bone marrow-derived progenitor cells. In addition to animal experiments, results of research on human tissues and organs are included.
New experiment therapies for old disease
Mucorales are fast-growing thermotolerant fungi that are ubiquitous in the environment. They have a worldwide distribution and are commonly found in decaying organic material or agricultural and forest soils (1). Mucormycosis is a group of mould infections caused by fungi in the class previously known as Zygomycetes now renamed Mucormycetes (2).
New diagnostic method th detect peritoneal metastases in colorectal cancer
Colorectal cancer is the third common reason of death in population worldwide therefore we will focus in our study about description of this type of cancer and its symptoms to raise the public awareness to go to the right specialist as soon as the symptoms appear to improve early detection of this disease and the overall survival and we will highlight the best diet and life style to avoid this type of cancer hopefully beside that we will present all the most successful therapies of this disease from different classes of compounds such as chemotherapy or anti angiogenic and Metformin and other bacterial therapy however the major goal of the experimental part of this research is performed to establish a new promising diagnostic tool by Near Infra-red camera after injection of indyocine green to detection the peritoneal metastasis of colorectal in 15 patients since this kind of metastasis
New Challenges in Superconductivity : Experimental Advances and Emerging Theories ; Proceedings of the NATO Advanced Research Workshop, held in Miami, Florida, 11-14 January 2004
This volume contains the proceedings of the 2004 University of Miami Workshop on Unconventional Superconductivity. The workshop was the fourth in a series of successful meetings on High-T Superconductivity and C related topics, which took place at the James L. Knight Physics Building on the University of Miami campus in Coral Gables, Florida, in January 1991, 1995, 1999, and 2004. The workshop consisted of two consecutive events: 1. NATO Advanced Research Workshop (ARW) on New Challenges in Superconductivity: Experimental Advances and Emerging Theories, held on January 11-14, 2004; 2. Symposium on Emerging Mechanisms for High Temperature Superconductivity (SEMHTS), held on January 15-16, 2004.
New Business Models for the Reuse of Secondary Resources from WEEEs : The FENIX Project
This book summarizes research being pursued within the FENIX project, funded by the EU community under the H2020 programme, the goal of which is to design a new product service paradigm able to promote innovative business models, to open added value to the vessels and to create new market segments. It experiments and validates its approach on three new concepts of added-value specialized vessels able to run requested services for several maritime sectors in the most effective, efficient, economic valuable and eco-friendly way. The three vessels share the same lean design methodology, IoT tools and HPC simulation strategy: a lean fact-based design model approach, which combines real operative data at sea with lean methodology, to support the development and implementation of the vessel concepts; IT customized tools to enable the acquisition, processing and usage of on board and local weather data, through an IoT platform, to provide business services to different stakeholders; HPC simulation, providing a virtual towing tank environment, for early vessel design improvement and testing. The book demonstrates that an integrated LCC analysis and LCC strategy to guarantee sustainability to vessels concepts and the proper environmental attention inside the maritime industry.
Neurotransmitter Transporters
The present volume of the Handbook of Experimental Pharmacology gives a representative survey of the current status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters and aims at providing an overview of insights that were generated in the past 5 years. If the volume serves as both, a useful compendium of current concepts and an inspiring starting point, it will have fulfilled its mission and will be a source for students interested in this emerging field as well as for experienced scientists looking for an update. This volume is the brainchild of the editor-in-chief of the HEP series, Klaus Starke, awe-inspiring to all pharmacologists of younger generations.
Neurodynamics of Cognition and Consciousness
This book addresses dynamical aspects of brain functions and cognition. This volume gives an overview of recent advances in this interdisciplinary field of cognitive and computer science related to dynamics of cognition, including experimental studies, dynamical modelling and interpretation of cognitive experiments, and theoretical approaches.
Neurodegeneration in Multiple Sclerosis
In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic reliability and to monitor the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy as to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is dramatically changing our understanding of how MS causes irreversible disability.
Neurodegeneration and Prion Disease
This volume provides an in-depth overview from world experts on prion disease. These fatal diseases include Creutzfeldt-Jakob disease, chronic wasting disease in deer, scrapie of sheep, bovine spongiform encephalopathy (mad cow’s disease) of cattle and related diseases. Understanding what causes neuronal death in these diseases is essential to both preventing and curing them. The most recent advances in understanding neuronal death in prion diseases are presented. Prion diseases serve as an experimental model for all neurodegenerative conditions. This book will provide understanding of neurodegeneration and provide an up-to-date record of the state of the art for other specialists and non-specialists in related fields.
Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
Networks : From Biology to Theory
The concept of a network emerges as a powerful and stimulating research paradigm in mathematics, physics and computer science, and demonstrates a very lively interaction between experimental findings, simulation studies, and theoretical investigations that then in turn lead to new experimental questions. This volume explores this concept in full and features contributions from a truly global set of contributors.
Networked Control Systems: Theory and Applications
Networked Control Systems presents the most recent results in stability and robustness analysis as well as new developments related to networked fuzzy and optimal control. Many of the chapters contain details of case-studies, experimental, simulation and/or other application-related work showing how the theories put forward can be implemented in real systems.
Navigational Surgery of the Facial Skeleton and Skull Base
Computer-assisted techniques in the surgery of the facial skeleton including the skull base are depicted for the very first time in this atlas of navigational surgery. Experienced surgeons as well as trainees will benefit from the detailed and well-illustrated information on the use of computer technology in clinical routine, accompanied by the experimental basis of intraoperative accuracy.The interdisciplinary approach brings together maxillofacial surgeons, plastic surgeons, ENT surgeons, and neurosurgeons. New methods of non-invasive referencing and the use of virtual models in the field of oral and cranio-maxillofacial surgery are demonstrated. Clinical cases illustrate the practical use of this new technique.
Natural product experiments in drug discovery
Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.
Nanostructured Soft Matter : Experiment, Theory, Simulation and Perspectives
This book provides an interdisciplinary overview of a new and broad class of materials under the unifying name Nanostructured Soft Matter. It covers materials ranging from short amphiphilic molecules to block copolymers, proteins, colloids and their composites, microemulsions and bio-inspired systems.
Nanostructured Coatings
Controlling the performance of structures and components of all sizes and shapes through the use of engineered coatings has long been a key strategy in materials processing and technological design. The ever-increasing sophistication of en- neered coatings and the rapid trend toward producing increasingly smaller devices with greater demands on their fabrication, properties and performance have led to signicant progress in the science and technology of coatings, particularly in the last decade or two. Nanostructured coatings constitute a major area of sci- ti?c exploration and technological pursuit in this development.Nanostructured coatings demand study in a highly interdisciplinary research arena which encompasses: surface and interface science study of defects modern characterization methodologies cutting-edge experimental developments to deposit.
