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In Vivo Models of Inflammation ; Vol. I

In Vivo Models of Inflammation (Vol. 1) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation.

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IAEA Atlas of Cardiac PET/CT : A Case-Study Approach

This book presents a wide portfolio of examples of positron emission tomography coupled with computer tomography (PET/CT) studies in various cardiac conditions in order to provide a rationale for the implementation of this technology in an array of clinical conditions. Cardiovascular diseases are a major contributor to premature morbidity and mortality worldwide. Low- and middle-income countries (LMICs) are particularly affected by cardiovascular diseases (CVDs), with more than 75% of all CVDs deaths occurring in these countries. For this reason, target 3.4 of the United Nations (UN) Sustainable Development Goals (SDGs) agenda aims at a 30% reduction in premature mortality due to non-communicable diseases (NCDs), which include CVDs, by 2030.

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Herbals as nutraceuticals : Their role in healthcare

Herbal nutraceuticals demonstrate a variety of therapeutic benefits and have been found to prevent, treat, and even cure a range of diseases. This new book provides insight into nutraceuticals and their function in human health, highlighting their antimicrobial and immune-inflammatory properties. It describes the nutraceutical properties of various medicinal herbs and details the role of nutraceuticals in treating diseases such as Alzheimer's, Parkinson's, obesity, diabetes, cancer, cardiovascular diseases, skincare issues, and more.

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Heart block

Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscle tissue, with the other two being skeletal muscle and smooth muscle. It is involuntary, striated muscle that constitutes the main tissue of the wall of the heart. The cardiac muscle (myocardium) forms a thick middle layer between the outer layer of the heart wall (the pericardium) and the inner layer (the endocardium), with blood supplied via the coronary circulation. It is composed of individual cardiac muscle cells joined together by intercalated discs, and encased by collagen fibers and other substances that form the extracellular matrix.

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Healthcare solutions using machine learning and informatics

Covers novel and innovative solutions for the healthcare that apply machine learning and biomedical informatics technology. The healthcare sector is one of the most critical in society. This book presents a series of artificial intelligence, machine learning, intelligent IoT-based solutions for medical image analysis, medical big data processing, disease predictions. Machine learning and artificial intelligence use cases in healthcare presented in the book give researchers, practitioners, and students a wide range of practical examples of cross-domain convergence. The wide variety of topics covered include: Artificial Intelligence in healthcare Machine learning solutions for such disease as diabetes, arthritis, cardiovascular disease, and COVID-19 Big data analytics solutions for healthcare data processing Reliable biomedical applications using AI models Intelligent IoT in healthcare. The book explains fundamental concepts as well as the advanced use cases illustrating how to apply emerging technologies such as machine learning, AI models, data informatics into practice to tackle challenges in the field of healthcare with real-world scenarios. Chapters contributed by noted academicians and professionals examine various solutions, frameworks, applications, case studies, and best practices in the healthcare domain

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Handbook of healthcare in the Arab World

Examines health and medical care in the Arab world from a systems biology approach. It features comprehensive coverage that includes details of key social, environmental, and cultural determinants. In addition, the contributors also investigate the developed infrastructure that manages and delivers health care and medical solutions throughout the region. More than 25 sections consider all aspects of health, from cancer to hormone replacement therapy, from the use of medications to vitamin deficiency in emergency medical care. Chapters highlight essential areas in the wellbeing and care of this population. These topics include women’s health care, displaced and refugee women’s health needs, childhood health, social and environmental causes of disease, health systems and health management, and a wide range of diseases of various body systems. This resource also explores issues related to access and barriers to health delivery throughout the region.

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Handbook of cardiovascular behavioral medicine

Cardiovascular disease is the leading cause of morbidity and mortality in the United States and worldwide. It is well recognized that traditional risk factors for cardiovascular disease have limited predictive utility in the identification of new cardiovascular disease cases and outcomes. Thus, investigators have argued that application of a biopsychosocial research paradigm in this field may be of particular utility in understanding cardiovascular disease pathogenesis. Accordingly, a subdiscipline within the field of behavioral medicine – cardiovascular behavioral medicine – examines interrelations among biological, behavioral, psychological, social, and environmental factors in cardiovascular health and disease.

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Enhancing the Dissolution Rate of Atorvastatin by Solid Dispersion Technique

In the last few decades, solid dispersion (SD) technology had been studied as an approach to produce an amorphous carrier to enhance the solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. The use of suitable carrier and methodology in the preparation of SDs play a significant role in the biological behavior of the SDs. Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. the solubility of atorvastatin in water is very low (0.1 mg mL− 1), which results in reduced bioavailability. In order to enhance its solubility, we have prepared solid dispersions (SDs) of atorvastatin at different drug: polymer ratios (1:2, 1:10, 1:20,1:25 and 1:40), using polyethylene glycol 6000 as polymer and different preparation methods (co-precipitate and melting methods) The characterization of the SDs was performed using differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) The solubility of AT was improved by the incorporation PEG6000.

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CRP and the relation with heart disease

Cardiovascular diseases are the leading causes of mortality and morbidity in industrialized and developing countries. Many efforts have been undertaken during the last decades to identify environmental, behavioral and genetic factors modulating the risk of cardiovascular diseases.It will explain the role of CRP - an acute-phase protein- as indicator of potential cardiovascular disease as well as a predictor of the risk for heart disease and future heart attack

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COVID-19 & Cardiovascular Complications

A highly pathogenic human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently recognized in Wuhan, China, as the cause of the coronavirus disease 2019 (COVID-19) outbreak which has spread rapidly from China to other countries in the world, causing a pandemic with alarming morbidity and mortality. The emerging epidemiological data about COVID-19 patients suggest an association between cardiovascular diseases (CVD) and SARS-CoV-2 infection, in term of clinical features at hospital admission and prognosis for disease severity. The aim of our review is to describe the cardiological features of COVID-19 patients at admission, the acute cardiac presentation, the clinical outcome for patients with underlying CVD and the pharmacological implications for disease management.

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Co-enzyme Q10

Coenzyme Q10 is a vitamin like substance that has been found in both microorganisms and plants as well as in animals and humans. In this research we will talk about CoenzymeQ10, it’s biochemical functions and roles in health and diseases such as Parkinson, cardiovascular diseases, diabetes, male fertility, cancers , covid19 and immune functions. Some coQ10 determination methods in foods will be discussed. At the last can we use it as asupplement? Does it have an adverse effects and contraindications? and what are the factors that affect on it’s plasma concentrations ? .

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Clinical psychology and heart disease

The publication offers a thorough and up-to-date review of scientific research supporting evidence of the relationship between cardiac disease and psychological condition, and offers practical suggestions for developing a clinical practice, and directions for future research in the new field of "cardiac psychology". Every chapter is authored by world-renowned researchers in the field.

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Male Sexual Function : A Guide to Clinical Management

Male Sexual Function: A Guide to Clinical Management, Second Edition, completely updates and reviews newer developments, including linking erectile dysfunction (ED) with lower urinary tract systems, advances in erectile physiology, and the appreciation of ED as a form of endothelial dysfunction and a harbinger of other potentially lethal forms of vascular disease. Treatments of ED as well as the background, causes, associated conditions, and diagnostic tools are also provided. This new updated edition also presents the facts of sexual function and dysfunction so that the practitioner can properly treat basic problems with easily prescribed therapies. Also included is a new chapter on cardiovascular disease as well as chapters on pelvic surgeries, intracavernous injections with vasoactive agents, and vacuum erection devices.

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Clinical Nutrition in Practice

Opens with introductory chapters on the basis of healthy nutrition, malnutrition and nutritional assessment. These are followed by chapters addressing the nutritional needs of patients with obesity, diabetes, cardiovascular disease, rheumatoid and neurologic disorders, as well as diseases of various organ systems, such as the GI tract, renal and pulmonary systems. Special attention is given to describing nutrition in cancer patients and those with HIV/AIDS and the book concludes with a discussion of enteral and parenteral nutrition.

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Cigarette Smoke and Oxidative Stress

From a public health point of view, there is little doubt that one of the most important preventable causes of disease worldwide is tobacco smoking. From a scientifc point of view, we found it of interest to make a comprehensive ov- view of what we presently know about oxidative stress and tobacco smoke, because sm- ing is presently the best-known common condition associated with oxidative stress, and it may serve as a model for others. To this end, we have asked distinguished researchers from the public and the private sectors to evaluate the present scientifc status in their particular area. Authors were selected purely because of their scientifc merits.

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Chronic diseases and health care : New trends in diabetes, arthritis, osteoporosis, fibromyalgia, low back pain, cardiovascular disease, and cancer

CHRONIC DISEASES AND HEALTH CARE: New Patterns of Diabetes, Arthritis, Osteoporosis, Fibromyalgia, Low Back Pain, Cardiovascular Disease, and Cancer. This book evaluates new trends in epidemiology, health care costs, risk factors, treatment and rehabilitation outcomes, stress and coping strategies, social support, disability, patient education, and self-management for seven prevalent chronic diseases.

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Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches

The cardiovascular system transports oxygen and nutrients to all parts of the body; therefore, any impediment to this system through, for example, a circulatory disorder, represents a serious threat to organs, tissues, and cells. Obstructive diseases of vessels with a diameter of more than 1 mm can be treated by conventional surgical and interventional approaches; however, blockages in small vessels with a diameter of less than 1 mm cannot be treated by conventional methods. As a consequence, therapeutic ang- genesis and vasculogenesis for the treatment of ischemic diseases have been widely studied in the last decade. These methods may contribute to the re­ pair of intractable cardiovascular diseases with a main vascular involvement in the body's smallest vessels. In this book, Hikaru Matsuda and I have tried to summarize recent Japanese developments in the field of cardiovascular regeneration therapies using tissue engineering.

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Cardiovascular Disease in AIDS

In this new edition of Cardiovascular Disease in AIDS new insights coming from basic and clinical research in the field of HIV-associated cardiovascular disease and antiretroviral therapy are reported, along with the clinical guidelines for a careful stratification of the cardiovascular risk and cardiovascular monitoring of HIV-infected patients receiving HAART. The authors offer a wide overview of the topic for specialists in cardiology and infectious diseases involved in the clinical management of HIV-infected patients.

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Cardiac CT imaging : Diagnosis of cardiovascular disease

This book collates all relevant imaging findings of the use of cardiac CT and presents them in a clinically relevant and practical manner appropriate for residents and fellows in both cardiology and radiology. The images have been supplied by an internationally renowned set of contributing authors and represent the full spectrum of cardiac CT imaging.

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Brain and Heart Dynamics

Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling.

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