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Ambisonics : A Practical 3D Audio Theory for Recording, Studio Production, Sound Reinforcement, and Virtual Reality
Provides a concise explanation of the fundamentals and background of the surround sound recording and playback technology Ambisonics. It equips readers with the psychoacoustical, signal processing, acoustical, and mathematical knowledge needed to understand the inner workings of modern processing utilities, special equipment for recording, manipulation, and reproduction in the higher-order Ambisonic format. The book comes with various practical examples based on free software tools and open scientific data for reproducible research. The book includes an extensive mathematical appendix. The book offers readers a deeper understanding of Ambisonic technologies, and will especially benefit scientists, audio-system and audio-recording engineers.
Ambient intelligence
Ambient intelligence is the vision of a technology that will become invisibly embedded in our natural surroundings, present whenever we need it, enabled by simple and effortless interactions, attuned to all our senses, adaptive to users and context-sensitive, and autonomous.
Alzheimer's disease : Peptide vaccine and immunotherapy
Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alvar Aalto and the future of architecture
Exposes dialogue between history, theory, design, construction, technology, and sensory experience by means of digital simulations that enhance the assessment and values of our material choices. It offers a critical look to the past to inspire the future. This new edition looks to Alvar Aalto as the primary protagonist for channeling discussions related to these topics. Architects like ALA, Shigeru Ban, 3XN, Peter Zumthor, and others also play the role of contemporary guides in this review. The work of Aalto and selected contemporary architects, along with computer modeling software, showcase the importance of comprehensive design.
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Altering nature ; Vol.2 : Religion, Biotechnology, and Public Policy
The two volumes of Altering Nature consider the complex ways that concepts of 'nature' and 'the natural' are understood and the relevance of those understandings to discussions of biotechnology.Volume Two, Religion, Biotechnology, and Public Policy, reviews recent religious and ethical analyses of four specific areas of biotechnology: assisted reproduction, genetic therapy and enhancement, human-machine incorporation, and biodiversity. It identifies and explores the richer normative themes that inform particular debates and suggests ways that policy choices in biotechnology may be illuminated by devoting greater attention to religious perspectives.
Alqadam Train Station
Aims to focuses on the redesign of the Southern Train Station of Damascus, located in the Al-Qadam area. The proposal aims to preserve the historical identity of the existing station while expanding it to meet the needs of modern urban mobility. The design balances heritage conservation with contemporary architectural expression, creating a space that respects the cultural fabric of Damascus while addressing future growth.Key elements include increasing station capacity, integrating sustainable design strategies, and enhancing passenger flow. Renewable energy use, passive ventilation, and green spaces are central to reducing environmental impact and improving user comfort. يركّز مشروع التخرج هذا على إعادة تصميم المحطة الجنوبية للقطارات في دمشق، الواقعة في منطقة القديهدف المشروع إلى الحفاظ على الهوية التاريخية للمحطة القديمة مع تطويرها وتوسيعها لتلبية احتياجات النقل الحضري المعاصر. يجمع التصميم بين صون التراث والتعبير المعماري الحديث، ليخلق فضاءً يحترم النسيج الثقافي لدمشق ويستجيب في الوقت نفسه لمتطلبات النمو المستقبلي. تشمل العناصر الأساسية زيادة القدرة الاستيعابية للمحطة، ودمج استراتيجيات التصميم المستدام، وتحسين حركة المسافرين. كما يعتمد المشروع على استخدام الطاقة المتجددة، والتهوية الطبيعية، وإضافة المساحات الخضراء لتقليل الأثر البيئي وتعزيز راحة المستخدمين.
Alpine Industrial Landscapes : Towards a New Approach for Brownfield Redevelopment in Mountain Regions
This book presents a pioneering research on brownfield redevelopment in mountain regions, and specifically in the European Alps. The origins and causes, the actual conditions as well as the future challenges and potentials of mountain brownfields are investigated from an interdisciplinary yet landscape-centered perspective. Through the reasoned combination of research-by-design methods and case-study analysis, the book explores the infrastructural relevance of these sites for the specific mountain territory, while advancing an innovative structuralist-systemic approach for their physical and functional transformation. The book includes, among others, a first transnational geo-mapping of Alpine brownfields, whose impressive outcomes in terms of site numbers and distribution can only confirm the urgency of this research.
Alpha-1 antitrypsin : Methods and protocols
Provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Allergy in Practice
This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.
Allergic Diseases : Diagnosis and Treatment
In this updated third edition of the critically-acclaimed volume, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. With an emphasis on common allergic diseases and the pharmacological tools to control them, Allergic Diseases: Diagnosis and Treatment, Third Edition disseminates the practical knowledge that practitioners have accumulated through practice and teaching in the field of allergy and immunology.
Aligner Techniques in Orthodontics
Filled with the theoretical and practical clinical information on the popular aligner techniques with a focus on Invisalign. Written by practicing orthodontists and noted experts on the topic, the book is designed to help practitioners develop their skills in using aligners in orthodontics. The authors describe in detail the clear and simple methods for treating patients using different aligner techniques, as well as material on treating any given malocclusion.
Algorithms on Trees and Graphs : With Python Code
Introduces graph algorithms on an intuitive basis followed by a detailed exposition using structured pseudocode, with correctness proofs as well as worst-case analyses. Centered around the fundamental issue of graph isomorphism, the content goes beyond classical graph problems of shortest paths, spanning trees, flows in networks, and matchings in bipartite graphs. Advanced algorithmic results and techniques of practical relevance are presented in a coherent and consolidated way. Numerous illustrations, examples, problems, exercises, and a comprehensive bibliography support students and professionals in using the book as a text and source of reference. Furthermore, Python code for all algorithms presented is given in an appendix. Topics and features: Algorithms are first presented on an intuitive basis, followed by a detailed exposition using structured pseudocode / Correctness proofs are given, together with a worst-case analysis of the algorithms / Full implementation of all the algorithms in Python / An extensive chapter is devoted to the algorithmic techniques used in the book / Solutions to all the problems
Algorithms in Bioinformatics ; Vol.4175 : 6th International Workshop, WABI 2006, Zurich, Switzerland, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the 6th International Workshop on Algorithms in Bioinformatics, WABI 2006, held in Zurich, Switzerland in September 2006 in the course of the ALGO 2006 conference meetings. The 36 revised full papers presented were carefully reviewed and selected from 100 submissions. All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. For the first time also machine-learning approaches along with combinatorial optimization are covered.
Algorithms in Bioinformatics ; Vol. 3692 ; 5th international workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005, Proceedings
this book present the proceedings of the 5th Workshop on Algorithmsin Bioinformatics (WABI 2005) which took place in Spain, 2005. The Workshop on Algorithms in Bioinformatics highlights research workspecifically developed to address algorithmic problems in biosequence analysis. The emphasis is therefore on statistical and probabilistic algorithms that addressimportant problems in the field of molecular and structural biology. the workshop aims to present recent research results, includingsignificant work in progress, and to identify and explore directions of futureresearch.Original research papers (including significant work in progress) or state-of-the-art surveys were solicited on all aspects of algorithms in bioinformatics,including, but not limited to: exact and approximate algorithms for genomics,genetics, sequence analysis, gene and signal recognition, alignment, molecularevolution, phylogenetics, structure determination or prediction, gene expressionand gene networks, proteomics, functional genomics, and drug design.
Algorithms in Bioinformatics ; 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007, Proceedings
All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. Furthermore the papers feature high-performance computing approaches to computationally hard learning and optimization problems in bioinformatics and cover methods, software and dataset repositories for development and testing of such algorithms and their underlying models.
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
