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Fungal Immunology: From an Organ Perspective
This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi.
Fungal Genomics
Presents an overview on mutualistic and pathogenic interactions between fungi and plants. This book offers reviews on fungal lifestyles, mechanisms of their interactions with their host plants, signal perception and transduction, and plant defense responses directed against attack by fungal pathogens. It is suitable for students in microbiology.
Fundamentals of Space Medicine
Topics discussed in this book include: adaptation of sensory-motor, cardio-vascular, bone, and muscle systems to the microgravity of spaceflight; psychological and sociological issues of living in a confined, isolated, and stressful environment; operational space medicine, such as crew selection, training and in-flight health monitoring, countermeasures and support; results of space biology experiments on individual cells, plants, and animal models; and the impact of long-duration missions such as the human mission to Mars. The author also provides a detailed description of how to fly a space experiment, based on his own experience with research projects conducted onboard Salyut-7, Mir, Spacelab, and the Space Shuttle. Now is the time to look at the future of human spaceflight and what comes next. The future human exploration of Mars captures the imagination of both the public and the scientific community. Many physiological, psychological, operational, and scientific issues need to be solved before the first crew can explore the enigmatic Red Planet. This book also identifies the showstoppers that can be foreseen and what we need to learn to fully understand the implications and risks of such a mission.
Fundamentals of Space Biology : Research on Cells, Animals, and Plants in Space
This book is intended as an overview at the undergraduate or early university level and describes the effects of spaceflight at cellular and organism levels. Past, current, and future research on the effects of gravity--or its absence--and ionizing radiation on the evolution, development, and function of living organisms is presented in layman's terms by researchers who have been active in this field. The purpose is to enlighten science and non-science readers to the benefits of space biology research for conducting basic and applied research to support human exploration of space. Also covered are the advantages of approaching the space environment as a laboratory for scientific, technological, and commercial research.
Fundamentals of Protein Structure and Function
This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic.
Fundamentals of Data Mining in Genomics and Proteomics
The book presents key analytical techniques used to analyze genomic and proteomic data by detailing their underlying principles, merits and limitations. An important goal of this text is to provide a highly intuitive and conceptual (as opposed to intricate mathematical) account of the discussed methodologies. This treatment will enable readers with interest in analysis of genomic and proteomic data to quickly learn and appreciate the essential properties of relevant data mining methodologies without recourse to advanced mathematics.
Fundamentals of biomechanics
The book presents a comprehensive review of the major concepts of biomechanics and summarizes them in nine principles of biomechanics. Throughout the text are numerous examples of applying these principles to the work of kinesiology professionals. Specific case studies are presented in four application chapters: physical education, coaching, strength and conditioning, and sports medicine.
Functional ultrastructure: Atlas of tissue biology and pathology
The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available. This atlas reminds us that the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.
Functional Neuroanatomy of Pain
Pain is an unpleasant but very important biological signal for danger. Nociception is necessary for survival and maintaining the integrity of the organism in a potentially hostile environment. Pain is both a sensory experience and a perceptual metaphor for damage and it is activated by noxious stimuli that act on a complex pain sensory apparatus. However, chronic pain having no more a protective role can become a ruining disease itself, termed "neuropathic pain".
Functional Biomaterials : Drug Delivery and Biomedical Applications
Explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field.
Fruits and Nuts
Genome Mapping and Molecular Breeding in Plants presents the current status of the elucidation and improvement of plant genomes of economic interest. The focus is on genetic and physical mapping, positioning, cloning, monitoring of desirable genes by molecular breeding and the most recent advances in genomics. The series comprises seven volumes: Cereals and Millets; Oilseeds; Pulses, Sugar and Tuber Crops; Fruits and Nuts; Vegetables; Technical Crops; and Forest Trees. Fruits and nuts form the largest group among crop plants. Several constraints such as long life cycle, heterozygosity and large plant size caused comparatively slow research progress in the past. The chapters on 20 fruit and nut crops authored by 56 renowned scientists from 12 countries include for the first time comprehensive reviews on mango, banana, olive, pineapple, pistachio, persimmon and papaya. Other crops covered are apple, grape, cherry, plum, peach, pear, apricot, strawberry, raspberry, blueberry, almond, citrus and avocado.
Frontiers in Research of the Renin-Angiotensin System on Human Disease
the major purpose of this seventh volume of Proteases in Biology and Disease series is to provide a topical and timely forum for the critical appraisal of an area of endocrine research that is expanding rapidly. In this book entitled “Frontiers in Research of the Renin-Angiotensin System on Human Disease”, a collection of 13 chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS in human disease.
From Innate Immunity to Immunological Memory
The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination rests. Therefore, understanding the mechanisms by which immunological memory is regulated is of paramount importance. Recent advances in immunology, particularly in the field of innate immunity, suggest that the innate immune system plays fundamental roles in influencing immunological memory. Indeed, emerging evidence suggests that events that occur early, within hours if not minutes of pathogen or vaccine entry profoundly shape the quantity, quality and duration of immunological memory. The present volume assembles a collection of essays from leading experts that span the entire spectrum research from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.
From globular proteins to amyloids
Proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations. Introduces basic rules for protein folding, along with the conditions that result in misfolding Presents research that lies in treating the aqueous environment as a continuum rather than a set of individual water molecules (i.e. the classic representation) Provides practical applications for helping the prevention of amyloidosis and improving drug design
From Energetics to Ecosystems : the Dynamics and Structure of Ecological Systems
Ecosystems are complex and enigmatic entities that are ultimately our life support systems. Understanding these systems to the point of being able to predict their behaviour in the face of perturbations requires that researchers adopt a number of strategies that vary in both approach and scale. This book, in a sense, is representative of some of the developments that have unfolded when math and physics met ecology. Here, some of the world’s leading ecologists examine ecosystems from theoretical, experimental, and empirical viewpoints, from energetics to ecosystems. The book begins with simplifying and synthesizing nature’s complex relationships. It then moves on to explore the mapping between food web structure and function and ends with the role of theory in integrating different research areas. From the breadth of systems analyzed to the rigor of approaches taken, this book is not only a useful resource for students and researchers in ecology, but also serves as a fitting tribute to the life and work of Peter Yodzis.
From Cells to Proteins : Imaging Nature across Dimensions ; Proceedings of the NATO Advanced Study Institute, held in Pisa, Italy, 12-23 September 2004
This book offers updated information on how much information we are able to obtain in the exploration of the inner details of biological specimens in their native structure and composition. And deals with the implementation of laser beam and stage scanning systems incorporating confocal optics or multiphoton microscopy; the advent of new electro-optical detectors with great sensitivity, linearity, and dynamic range; the possibility of 2D fast image enhancement, reconstruction, restoration, analysis and 3D display, and the application of luminescence techniques.
From Biological Control to Invasion : the Ladybird Harmonia axyridis as a Model Species
Harmonia axyridis has been described as the "most invasive ladybird on Earth". It has a long history of use as a classical biological control agent in the USA and more recently in Europe. This beetle has been effective at controlling pest insects in a variety of crop systems but it poses unacceptable risks by impacting on non-target species as both an intraguild predator and competitor.Written by renowned scientists, this book is a synthesis of recent research on H. axyridis and provides informative insights into current perspectives and future directions. Biological control is an essential component of sustainable agriculture but the distinction between a successful biological control agent and an invasive species can be narrow. We hope that lessons can be learnt from H. axyridis.
Freshwater Animal Diversity Assessment
The Freshwater Animal Diversity Assessment gives a state of the art assessment of the diversity and distribution of Metazoa in the continental waters of the world. The project deals with all major animal groups plus the macrophytes, and encompasses the complete array of terrestrial aquatic ecosystems. It is the most comprehensive study of species- and genus-level diversity and chorology of the global freshwater fauna to date, and is the first to present comparable data on the different faunal groups concerned. The project draws from the collected expertise of numerous world-renowned taxonomic experts that have bundled efforts to produce this outstanding volume. The result is invaluable to all scientists, managers and conservationists interested in non-marine aquatic animals.
Free-Radical-Induced DNA Damage and Its Repair : A Chemical Perspective
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.
Fragmentation in Semi-Arid and Arid Landscapes : Consequences for Human and Natural Systems
Exploring the concept of fragmentation, the ecological processes interrupted by fragmentation, and the social consequences of fragmented landscapes, this book presents a timely synthesis on the effects of fragmentation on arid and semi-arid pastoral systems throughout the world. the authors examine how fragmentation occurs, the patterns that result, and the consequences of fragmentation for ecosystems and the people who depend on them. The book will provide a valuable reference for students and researchers in rangeland ecology, park and natural resource management, environmental and ecological anthropology, economics and agriculture.
