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Innovative Endocrinology of Cancer

Deals with developments in such topics as mechanisms of hormonal carcinogenesis, epidemiology and risk factors, hormone production by tumor tissue and hormonal sensitivity of the latter, genesis, dichotomy and endocrinology of cancer in females, and pharmacogenomics and proteomics in oncoendocrinology.

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Innovations in healthcare and outcome measurement : New approaches for a healthy lifestyle

Aims to bring up-to-date new ideas, opinions, development, and critical issues in healthcare and personalized medicine. We are interested in relevant articles covering a broad range of topics, such as: Advances in medical devices, Digitalization and data-driven technologies, AI and algorithm-based drug development (molecule building, enhancement, clinical trials), Diagnostic imaging, Personalized medicine, Nutrition, Oral health care, Healthcare management in certain diseases and population groups, Regulatory developments, Data management, Digital healthcare.

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Innovation in Life Cycle Engineering and Sustainable Development

Business models, which aims at determining how efficient can be a life cycle strategy from different point of view (customer, policy, environment, economics,…). End of life strategies, presenting recent approaches and technological solutions for end-of life treatments. Product development for sustainability, which aims at showing how designers integrate environmental conside- tions to improve their solutions. Product life cycle management, dealing with methods and tools to support life cycle considerations.

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Innervation of the Mammalian Esophagus

The esophagus is a relatively simple though vital organ. Beyond its role of propelling food from the pharynx to the stomach by a propulsive contraction wave representing the esophageal phase of deglutition, it is more recognized as a sensory organ from which a variety of respiratory and cardiovascular reflexes can be triggered.

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Innate Immunity of Plants, Animals, and Humans

This book wants to give an overview of our current knowledge about the innate immune system of plants, animals and humans. It not only covers the innate immune mechanisms and responses of so diverse organisms such as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans as well as the central defense mechanisms, antimicrobial peptides and the complement system.

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Innate and Adaptive Immunity in the Tumor Microenvironment

Recent studies, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues.

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Injuries in Athletics : Causes and Consequences

This book focuses on both applied and conceptual issues regarding the classification of injuries, common coaches’ errors leading to injury, coaches and athletes’ viewpoints on injury, the development of psychological trauma in athletes, traumatic brain injuries and basic principles of rehabilitation. It is organized into five parts: - Foundations of injuries in athletics - Coaches and Athletes’ perspectives of injury - Psychological traumas in athletes - Concussion in athletics - Injury rehabilitation This reference book accumulates the latest developments in the science of athletes' training, from "injury-free" perspectives along with psychological analyses, evaluation, and management of sport-related injuries. It is an ideal resource for coaches, clinical practitioners, researchers and students interested in kinesiology, sport psychology and athletic training.

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Injecting Salmonella Bacteria in to the Tumor Cures Cancer

The human body is inhabited by millions of tiny living organisms like good bacteria. We acquire these bacteria during birth and the first years of life, and they live with us throughout our lives. The human microbiomes are involved in healthy growth, in protecting the body from invaders, in helping digestion, and in regulating moods, but sometimes these bacteria can also be harmful. We need to take good care of our health to avoid the development of some diseases, like salmonella for example. Salmonella infections in humans can range from self-limiting gastroenteritis typically associated with non-typhoidal Salmonella (NTS) to typhoidal fever, which can be life-threatening. Salmonellosis causes considerable morbidity and mortality in both humans and animals, and has a significant socioeconomic impact worldwide.

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Inhibitory Regulation of Excitatory Neurotransmission

This book reviews aspects of GABAA receptor function, as well as the properties of a variety of other important inhibitory proteins, such as GABAC receptors, G-protein coupled receptors (specifically, GABAB receptors, metabotropic glutamate receptors and neuropeptide receptors), glycine receptors, GABA transporters and potassium channels. In addition, the consequences of mutations that disrupt the regulation of excitatory neurotransmission, and efforts to target the GABAergic system for therapeutic benefit, are discussed.

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Inhibitors of protein kinases and protein phosphates

The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases.

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Information Technologies in Environmental Engineering ; ITEE 2007 - 3rd International ICSC Symposium

Potentially dangerous environmental changes are happening in the atm- phere, oceans, animal habitats and places where hazardous materials are used, or have been discarded without adequate environmental protections. These increasing problems that also affect human health demand for int- disciplinary approaches where engineers, natural scientists, economists and computer scientists work together. This book publishes the results of the ITEE 2007 conference where information about the topics above has been presented and discussed among environmental engineers, computer scientists and economists.

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Information and self-organization : A macroscopic approach to complex systems

This book presents the concepts needed to deal with self-organizing complex systems from a unifying point of view that uses macroscopic data. The various meanings of the concept "information" are discussed and a general formulation of the maximum information (entropy) principle is used. With the aid of results from synergetics, adequate objective constraints for a large class of self-organizing systems are formulated and examples are given from physics, life and computer science. The relationship to chaos theory is examined and it is further shown that, based on possibly scarce and noisy data, unbiased guesses about processes of complex systems can be made and the underlying deterministic and random forces determined. This allows for probabilistic predictions of processes, with applications to numerous fields in science, technology, medicine and economics. The extensions of the third edition are essentially devoted to an introduction to the meaning of information in the quantum context. Indeed, quantum information science and technology is presently one of the most active fields of research at the interface of physics, technology and information sciences and has already established itself as one of the major future technologies for processing and communicating information on any scale.

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Information and its role in nature

Infromation and Its Role in Nature presents an in-depth interdisciplinary discussion of the concept of information and its role in the control of natural processes. After a brief review of classical and quantum information theory, the author addresses numerous central questions, including: Is information reducible to the laws of physics and chemistry? Does the Universe, in its evolution, constantly generate new information? Or are information and information-processing exclusive attributes of living systems, related to the very definition of life? If so, what is the role of information in classical and quantum physics? In what ways does information-processing in the human brain bring about self-consciousness? Accessible to graduate students and professionals from all scientific disciplines, this stimulating book will help to shed light on many controversial issues at the heart of modern science.

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Information and communication technologies and real-life learning : New education for the knowledge society

The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.

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Influenza Vaccines for the Future

The threat constituted by the multiple outbreaks of avian influenza during the last few years is urgently calling for the development of new influenza vaccines. Fortunately, a quantum leap in technology has revolutionized the study of influenza and the engineering of new vaccine strains by reverse genetics. This volume provides a historical background and state-of-the-art information about the recent advances in the biology of influenza and the design of new influenza vaccines.

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Inflammatory Bowel Disease and Familial Adenomatous Polyposis : Clinical Management and Patients' Quality of Life

Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. IBD and FAP represent a challenge for a multidisciplinary medical approach where different personnel play major roles in different stages of the patient’s treatment.

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Inflammation in the Pathogenesis of Chronic Diseases : The COX-2 Controversy

In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors.

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Inflammation and natural products ; 1st ed.

Brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes.

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Infectious diseases from nature : Mechanisms of viral emergence and persistence

many outstanding virologists and others presented papers under the broad theme of "emergence". The intent was to elucidate the diseases themselves, the mechanisms by which they have emerged, the publication perception and response to the diseases, and the possibility of prevention or prediction. The papers in this book summarize the talks of this meeting.

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Infectious Diseases and Substance Abuse

The influence of many drugs of abuse - licit and illicit - on immune function has been examined extensively over the years. This volume, part of the "Infectious Agents and Pathogenesis" series, examines a variety of drugs of abuse and how they affect the immune system

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