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Therapeutic use of medicinal plants and their extracts ; Vol.2 : Phytochemistry and bioactive compounds
Starts with a general introduction to phytochemistry, followed by chapters on plant constituents, their origins and chemistry, but also discussing animal-, microorganism- and mineral-based drugs. Further chapters cover vitamins, food additives and excipients as well as xenobiotics and poisons. The book also explores the herbal approach to disease management and molecular pharmacognosy and introduces methods of qualitative and quantitative analysis of plant constituents. Phytochemicals are classified as primary (e.g. carbohydrates, lipids, amino acid derivations, etc.) or secondary (e.g. alkaloids, terpenes and terpenoids, phenolic compounds, glycosides, etc.) metabolites according to their metabolic route of origin, chemical structure and function. A wide variety of primary and secondary phytochemicals are present in medicinal plants, some of which are active phytomedicines and some of which are pharmaceutical excipients.
Therapeutic use of medicinal plants and their extracts ; Vol.1: Pharmacognosy
This volume focuses on the importance of therapeutically active compounds of natural origin. Natural materials from plants, microbes, animals, marine organisms and minerals are important sources of modern drugs. Beginning with two chapters on the development and definition of the interdisciplinary field of pharmacognosy, the volume offers up-to-date information on natural and biosynthetic sources of drugs, classification of crude drugs, pharmacognosical botany, examples of medical application, WHO´s guidelines and intellectual property rights for herbal products.
Therapeutic proteins : Methods and protocols
Covers the latest key aspects of therapeutic protein applications. Chapters in this book cover topics such as the discovery, production, and conjugation of protein-proteins with discussions on the direction of future development and advancements; ways to use these engineering proteins for therapeutic and vaccine applications; and the use of modified protein nanocarriers.
Therapeutic medicinal plants in traditional persian medicine
Traditional Persian Medicine (TPM) is one of the oldest medical doctrines, globally known due to pioneering physicians and scientists. The greatest source of natural medicines in TPM originates from medicinal plants. Therapeutic Medicinal Plants in Traditional Persian Medicine provides a background on the history of TPM, as well as an introduction to 40 of the most popular medicinal plants used in TPM. It is a practical guide for readers interested in medicinal plants used in the prevention, management, and treatment of different diseases.
Therapeutic Management of Incontinence and Pelvic Pain : Pelvic Organ Disorders
Chapters include coverage of the management and treatment of bladder and bowel dysfunctions in men and women, pelvic organ prolapse; issues concerning the elderly, neurologically impaired patients and those with pelvic pain. Allied updated chapters are presented on research methodology, the importance of fluids and infection control. Other new chapters are concerned with quality of life, the treatment of bladder and bowel dysfunction in children, the history of pelvic floor muscle exercise and manual therapy. In addition, the use of real-time ultrasound to evaluate pelvic floor muscle contractility, exercise balls to promote coordination of trunk stabilisers and the pelvic floor muscles, and the role of the Occupational Therapist in the continence service are discussed. Finally, a new section on ethical issues regarding the management of incontinence completes this well-illustrated text.
Therapeutic Lipidology ; 1st ed.
This volume will provide practicing clinicians with a focused and intensive but useable source of information on the identification and management of dyslipidemias. Among the topics discussed in this groundbreaking text are lipoprotein metabolism, pharmacological therapy for cardiovascular disease, thiazolidinediones on serum lipoproteins, hypertriglyceridemia, dyslipidemia and obesity, dyslipidemia in children, and much more.
Therapeutic Lipidology ; 2nd ed.
The chapters focus on recent advances in the field including novel biomarkers and the microbiome, genomics of cardiovascular risks, PCSK9 inhibitors, imaging technologies, and epidemiology of atherosclerotic cardiovascular disease. The book describes new guidelines, novel therapeutic agents, and changes in the understanding of specific lipoproteins and subclasses with regard to their relationships to cardiovascular disease risk. The second edition contains more than thirty chapters covering such topics as the history of lipidology, lipoprotein metabolism and vascular biology, disorders of lipid metabolism, lifestyle/dietary and pharmacologic management for dyslipidemia, the management of dyslipidemia in certain subgroups (e.g., women, children, older patients) and lipid testing, as well as an examination of other biomarkers and testing procedures related to atherosclerosis and cardiovascular disease.
Therapeutic Hypothermia
This volume will be of interest to both the researcher interested in therapeutic hypothermia as well as the clinician interested in the potential use of therapeutic hypothermia in their patient population.
Therapeutic drug targets and phytomedicine For triple negative breast cancer
Provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. Introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. Helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.
Therapeutic Dressings and Wound Healing Applications
Takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: Debridement and disinfection properties of wound dressing / Biofilms, silver nanoparticles, and honey dressings / Clinical perspectives for treating diabetic wounds / Treating mixed infections / Wound healing and tissue regeneration treatments / Gene based therapy, 3D bioprinting and freeze-dried wafers
Therapeutic approaches in cancer treatment
A unique blend of structured information covering a broad area relevant to cancer therapeutics.This book comprises fourteen chapters covering cancer genomic approaches for cancer treatment, traditional modalities, chemotherapy, radiotherapy, hormonal therapy, immunotherapy, oncolytic virotherapy, which is another emerging field. Furthermore, it also covers targeted therapies in personalized medicine, which is again an emerging yet promising field for cancer treatment. Use of nanocarriers in the cancer treatment is another important aspect which is a developing thrive. This book is also unique about in covering psychological elements in cancer treatments and providing knowledge for nutritional assessments in cancer treatment. The book has very good text highlighting the important features with a blend of traditional and emerging treatment modalities. Furthermore, chemoresistance development and challenges it poses in cancer treatment along with the pharmacogenetics of anticancer drug, which is way important for the clinicians to understand for their individual patients, associated toxicities, and clinical responses to a particular drug.
Therapeutic Applications of Honey and its Phytochemicals ; Vol.2
Provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.
Therapeutic Applications of Honey and its Phytochemicals ; Vol.1
Provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.
Therapeutic antibodies : Methods and protocols
Covers methods for studying, producing, and analyzing therapeutic antibodies, measuring their concentration, developing neutralizing antibodies for them, and for predicting and monitoring their therapeutic efficacy and clinical effects. These biologics are the fastest growing pharmaceutical drug group and have had tremendous clinical and scientific impact in cancer, autoimmune diseases, infectious diseases, and other immune-related diseases, making the content of this volume essential. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible methods, and tips on troubleshooting and avoiding known pitfalls.
Therapeutic Antibodies
Antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions and are becoming the molecules of choice for further combination therapies and cell engineering. Current developments and clinical successes are summarised by experts in the drug development field. A must read for immunologists, clinical scientists and novel drug developers.
Therapeutic Angiogenesis – Quo vadis
This collection of current and future concepts of neovascularization offers fascinating insights into refining a powerful therapeutic tool which has not yet had the chance to live up to the expectations and needs of the medical community.
Theory of the Muon Anomalous Magnetic Moment
The theory of the muon anomalous magnetic moment is at the cutting edge of current research in particle physics. It includes multiloop calculations in both QED and electroweak theory, precision low-energy hadron physics, isospin violations and scattering of light by light. Any deviation between the theoretical prediction and the experimental value might be interpreted as a signal of an as-yet-unknown new physics. This book provides a comprehensive review of the theory of the muon anomalous magnetic moment.
Theory of Periodic Conjugate Heat Transfer
A new calculation method is presented for heat transfer in coupled convective-conductive fluid-wall systems under periodical intensity oscillations in fluid flow. It is demonstrated that the true steady-state mean value of the heat transfer coefficient has to be multiplied by a newly defined coupling factor. This correction factor is always smaller than one and depends on the coupling parameters Biot number, Fourier number as well as dimensionless geometry and oscillation parameters. For characteristic periodic heat transfer problems, analytical solutions are given for the coupling factor. To facilitate engineering application, the monograph also presents the analytical results in accompanying tables and diagrams.
Theory and Simulation of Hard-Sphere Fluids and Related Systems
Hard spheres and related objects (hard disks and mixtures of hard systems) are paradigmatic systems: indeed, they have served as a basis for the theoretical and numerical development of a number of fields, such as general liquids and fluids, amorphous solids, liquid crystals, colloids and granular matter, to name but a few. The present volume introduces and reviews some important basics and progress in the study of such systems. Their structure, thermodynamic properties, equations of state, as well as kinetic and transport properties are considered from different and complementary points of view.
Theory and Mathematical Methods for Bioformatics
This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics.
