Children's Exploration and Cultural Formation
This book examines the educational conditions that support cultures of exploration in kindergartens. It conceptualises cultures of exploration, whether those cultures are created through children’s own engagement or are demanded of them through undertaking specific tasks within different institutional settings.
Chemokines and Viral Infection
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
Chemistry from First Principles
This book examines the appearance of matter in its most primitive form, from the vacuum and the diversity that results from the fusion of elementary units in the genesis of atomic matter; considers the empirical rules of chemical affinity that regulate the synthesis and properties of molecular matter; analyzes the compatibility of the theories of chemistry with the quantum and relativity theories of physics; formulates a consistent theory, based on clear physical pictures and manageable mathematics, to account for chemical concepts such as the structure and stability of atoms and molecules, the periodicity of nuclides and elements, valence states, activation and chemical reactivity, electronegativity and general covalency, the exclusion principle, electronic energy, orbital angular momentum and spin in relation to molecular shape, torsional rigidity, chirality and molecular modeling; explains the self-similarity between space-time, nuclear structure, covalent assembly, biological growth, planetary systems and galactic conformation.
Changing Land Use Patterns in the Coastal Zone : Managing Environmental Quality in Rapidly Developing Regions
Coastal ecosystems make up some of the most important, yet most endangered, regions in the world. The protection of the unique processes that take place in these ecosystems requires that partnerships be formed among ecologists, resource managers, and planners. Experienced in the challenges of coastal system analysis, the contributors to this book provide multidisciplinary guidance on the assessment and management of environmental impacts caused by development. Each chapter examines an issue important to these fragile ecosystems, first presenting a non-technical summary of the issue and a review of the current state of the knowledge, then following with data and a more detailed consideration of the topic.
Central Bank Policy Mix : Issues, Challenges, and Policy Responses: Handbook of Central Banking Studies
Keynote speeches, lectures, and related teaching materials during the five years of the "Central Bank Policy Mix: Issues, Challenges and Policy Responses" flagship program of the BI Institute, the learning and research centre of Bank Indonesia. The book examines the interactions among central bank policies including monetary policy, exchange rate policy, macroprudential policy, and capital flow management and also elaborates on modeling issues and quantitative analysis of the interaction between macroeconomic variables and policy instruments.
Cementation in dental Implantology : An evidence-based guide
Examines in detail the issues associated with cementation in dental implantology, with a particular focus on residual excess cement and its consequences. It provides reliable guidance on cement selection and use on the basis of the latest scientific research.
Cathodic protection for reinforced concrete structures
For specialist contractors, large consultants and owners of corrosion damaged structures, and looks at international experience with this technique. It examines why corrosion is occurring, the differences in the application of CP with the stark dichotomy in its success and failure, and finally ways in which its performance can be improved on future installations.
Care in Healthcare : Reflections on Theory and Practice
This book examines the concept of care and care practices in healthcare from the interdisciplinary perspectives of continental philosophy, care ethics, the social sciences, and anthropology. Areas addressed include dementia care, midwifery, diabetes care, psychiatry, and reproductive medicine. Special attention is paid to ambivalences and tensions within both the concept of care and care practices. Contributions in the first section of the book explore phenomenological and hermeneutic approaches to care and reveal historical precursors to care ethics. Empirical case studies and reflections on care in institutionalised and standardised settings form the second section of the book.
Cable stayed bridges, Second ed.
The cable stayed bridge is an elegant, economical and efficient structure. Virtually unknown 40 years ago, these bridges have become increasingly important as their properties have been more fully understood. They have recently proved to be highly cost-effective for short to medium spans. The second edition of this extremely popular book has been updated and enhanced to cover the rapid technological progress in this field. Exceptionally well illustrated, the book examines all aspects of the design of cable stayed bridges.
Business and Professional Ethics
Learn why ethical behavior is so important and how to recognize potential pitfalls that involve much more than memorizing rules. You master the skills to develop a corporate culture of integrity that maintains stakeholder support and enables directors and auditors to complete their jobs. You also learn how to use ethical strategies to make decisions, as this edition examines the latest information on governance scandals, legal liability and professional accounting and auditing issues.
Building from tradition : Local materials and methods in contemporary architecture
Examines the recent resurgence of interest in the handmade building and the use of local and renewable materials in contemporary construction. In the past, raw materials were shaped to provide shelter and to accommodate the cultural, social, and economic needs of individuals and communities. This is still true today as architects, engineers, and builders turn once again to local resources and methods, not simply for constructing buildings, but also as a strategy for supporting social engagement, sustainable development, and cultural continuity. Building from Tradition features global case studies that allow readers to understand how building practices-developed and refined by previous generations-continue to be adapted to suit a broad range of cultural and environmental contexts. The book provides: a survey of historical and technical information about geologic and plant-based materials such as: stone, earth, reed and grass, wood, and bamboo; 24 detailed case studies examining the disadvantages and benefits to using traditional materials and methods and how they are currently being integrated with contemporary construction practices
Bright modernity : Color, commerce, and consumer culture
Color is a visible technology that invisibly connects so many puzzling aspects of modern Western consumer societies research and development, making and selling, predicting fashion trends, and more. Building on Regina Lee Blaszczyk’s go-to history of the “color revolution” in the United States, This book explores further transatlantic and multidisciplinary dimensions of the topic. Covering history from the mid nineteenth century into the immediate past, it examines the relationship between color, commerce, and consumer societies in unfamiliar settings and in the company of new kinds of experts. Readers will learn about the early dye industry, the dynamic nomenclature for color, and efforts to standardize, understand, and educate the public about color.
Brexit and the Control of Tobacco Illicit Trade
This book assesses the consequences of Brexit for the control of illicit trade in tobacco products in the UK and EU. Based on the currently applicable legal framework, it examines the significance of a possible non-application of the acquis communautaire in the UK in matters relating to anti-illicit trade in tobacco legislation.
Branded content : The fateful merging of media and marketing
This is a critical study of the changing relationship between media and marketing communications in the digital age. It examines the growth of content funded by brands, including brands’ own media, native advertising, and the integration of branded content across film, television, journalism and publishing, online, mobile, and social media.
Bone remodeling and osseointegration of implants
Provides an insight into the latest advances in bone fracture healing and remodeling algorithm and their incorporation into patient-specific finite element models and the use of machine learning and artificial intelligence to predict the bone regeneration and osseointegration process with a certain degree of accuracy. It also examines the applications of numerical models to simulate the fracture healing process, which may prove to be advantageous in determining the optimal mechanical-based treatment or reconstruction after an accident or illness.
Biopharmaceutical drug design and development
Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.
Biomedical applications and toxicity of nanomaterials
Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
Biomaterials and bionanotechnology ; 1st ed.
Examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.
Biomarkers in periodontal health and disease : Rationale, benefits, and Future directions
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.
Biomacromolecules : Carbohydrates, lipids, proteins and nucleic acids
The first chapter looks at the structural formulas and cyclic forms of monosaccharides, as well as their synthesis and breakdown. Cyclization, enolization, isomerization, tautomerization, mutarotation, and epimerization are all briefly described. Examples of disaccharides and polysaccharides are also presented. The second chapter covers triglycerides, steroids, vitamins, and their constituents. The third chapter examines the primary structure of proteins, including amino acid properties, peptide bond formation, and peptide synthesis. It also addresses secondary, tertiary, and quaternary structures. The book concludes with a chapter on nucleic acids, which covers the chemistry of nucleosides and oligonucleotides as well as topics such as genetic code, DNA secret code, Polymerase Chain Reaction and DNA fingerprinting.



















