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Drug delivery technology : Herbal bioenhancers in pharmaceuticals
Bioenhancers have been used in Ayurveda historically and are now being investigated for their pharmacological effi cacy. Herbal bioenhancers work on the gastrointestinal tract to improve absorption and drug bioavailability by acting on the drug metabolic process. Many herbal drugs show low activity due to their poor lipid solubility or improper molecular size. Piperine, gingerol, naringin, quercetin, niaziridin, glycyrrhizin, allicin, curcumin, genistein and others are able to enhance the bioavailability of active pharmaceuticals. This book details various facets of herbal bio-enhancers in a single comprehensive text.
Drug delivery approaches and nanosystems ; Vol.1 : Novel drug carriers
Presents a full picture of the state-of-the-art research and development in drug delivery systems using nanotechnology and its applications. It addresses the ever-expanding application of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques.
Drug delivery : An integrated clinical and engineering approach
Offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications.
Drug and Biological Development : From Molecule to Product and Beyond
Drug and Biological Development: From Molecule to Product and Beyond offers a complete discussion of product development in the pharmaceutical and biotechnology industries from discovery to product launch, continuing through life cycle management. The book is organized for optimal usefulness in the education and training of health care professionals. The text's narrative descriptions are enhanced by real-life examples, illustrations, controversies in industry, and references. Dr. Ronald Evens and his contributors are industry and research experts in a variety of disciplines.
Drug and Alcohol Abuse : A Clinical Guide to Diagnosis and Treatment
Gives professionals and students across the health and mental health disciplines a working knowledge of drug-related pathology, beginning with pharmacology, drug mechanisms, and genetic factors. This title features clinical/emergency orientation suited to both chronic misuse and acute situations.
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
Drug Absorption Studies : In Situ, In Vitro and In Silico Models
In the last 15 years, a great number of cell- or tissue-based in vitro models have been introduced into the biopharmaceutics arena. These models mimic the different biological barriers that a drug has to overcome to finally reach its target organ/cell/receptor. These in vitro models have been found very useful in not only characterising the permeability behaviour of drugs molecules in epithelial and endothelial tissues, but also studying drug delivery systems for improved delivery and enhanced absorption. Compared to the complex in vivo situation, in vitro models offer a fast, convenient approach with cost advantages most of times. Most importantly, they can be standardised and automatised to be applicable to the high-throughput screening. Starting at the molecular level of studies, continuing with cell monolayer models (both primary and cell lines) and in situ techniques as a final testing format, the book provides a practical approach to contemporary in vitro techniques for drug absorption studies. In addition, chapters on high-throughput assays, in vitro-in vivo correlation, bioinformatics and regulatory issues are covered, giving a comprehensive overview of available models and techniques. Moreover, an appendix comprised with a number of practical protocols is available online, updated as needed, should prove very helpful to apply the techniques directly to the benchside.
Driving digital transformation through data and AI : A practical guide to delivering data science and machine learning products
Explains how to build the organizational capability to deliver Data and AI products and drive immediate business results as new digital technologies significantly disrupt business Provides best practices, tools and templates for managing the organizational and technological change process to become an AI-driven enterprise Includes a variety of international case studies across several industries such as insurance, fashion, consumer goods, finance, technology and automotive Outlines how to develop a product strategy, build teams and design the platform and architecture Provides key principles for sharing knowledge, educating staff on data and AI, and effectively engaging top executives
Dream catcher
Dream Catcher is a video generation application that helps in many fields as science fiction, imagine event’s scenarios, education, animation and montage. By applying artificial algorithms implemented and trained on a dataset containing video samples and there descriptions to generate videos from any given text. The idea of generating videos from text is a new idea that was first presented at 2017, even that international companies like Google and OpenAi In the last year, was working on developing models to generate images from text. To make it easier to use the application, there are many ways to enter the text either by an image, voice or Typing from the keyboard.
Drawing imagining building : Embodiment in architectural design practices
Drawing Imagining Building focuses on the history of hand-drawing practices to capture some of the most crucial and overlooked parts of the process. Using 80 black and white images to illustrate the examples, it examines architectural drawing practices to elucidate the ways drawing advances the architect’s imagination.
Draughtsmen, Botanists and Nature : The Construction of Eighteenth-Century Botanical Illustrations
This book is the first in-depth study of eighteenth-century botanical illustrations, and its findings offer a completely new insight into the working practices of the botanists and scientific draughtsmen of this period. The author describes the different production stages of these illustrations, traces their uses by means of the private correspondence of participants and the documentation of the learned societies and academies, and explores their visual language, with particular emphasis placed on the difficult issue of colour. Finally, and for the first time, the author presents a convincing description of how these botanical illustrations developed.
Double Fertilization : Embryo and Endosperm Development in Flowering Plants
Double Fertilization" provides a comprehensive overview of all aspects of this central event in the reproduction and development of flowering plants. Written by Val Raghavan, The Ohio State University, an acknowledged expert in plant developmental biology, the book vividly describes the molecular and cellular steps of the unique and complex fertilization process that culminates in the formation of embryo and endosperm, focusing on the latest results from the model plant Arabidopsis. The text is complemented by excellent illustrations, including 16 color plates.
Double & Multiple Stars, and How to Observe Them
The first part of Jim Mullaney’s book provides a comprehensive review of the different classes of double and multiple systems, along with a look at the astrophysics of these objects. This is followed by a detailed guide for amateur astronomers, describing how to observe them – using a variety of different techniques – and outlining how to record the observations.In one book, here is all you need to observe double and multiple stars, and to understand the systems you are looking at.
Doors : History, repair and conservation
Guides you through the function, history, development, care, repair and conservation of doors by chapter authors who are experts in their field. This book offers depth and range of detail from dating and archaeology right through to the surveying, recording, engineering and curation of the door, its furniture and the part of the building into which it is set.
Don’t Panic with Mechanics! : Fun and success in the "loser discipline" of engineering studies!
The ultimate companion in the classical horror discipline of engineering science! Contents of the book are the basics of mechanics as treated in engineering and physical sciences: Statics, Elastostatics, Kinematics & Kinetics in unconventional, humorous presentation with many cartoons, funny explanations and a chapter containing several exercises with detailed solutions.
Domain Modeling and the Duration Calculus : International Training School, Shanghai, China, September 17-21, 2007, Advanced Lectures
The book presented provide competent coverage of software security, domain modeling of software engineering, and duration calculus for real time systems - originating from lectures of leading experts in these fields from Europe and Asia.It addressed in detail are: development of real-time systems, domain engineering using abstract modeling, the area of duration calculus, and formal methods like language description using the operational semantics approach.
Domain Decomposition Methods in Science and Engineering XVII
This volume contains a selection of papers presented at the 17th International Conference on Domain Decomposition Methods in Science and Engineering held at St. Wolfgang / Strobl, Austria, July 3 - 7, 2006. Domain decomposition is an active, interdisciplinary research area concerned with the development, analysis, and implementation of coupling and decoupling strategies in mathematical and computational models. Domain decomposition techniques provide efficient tools for treating problems in all Computational Sciences. The reader will become familiar with the newest domain decomposition technologies and their use for modeling and simulating of complex problems from different fields of applications.
Domain Decomposition Methods in Science and Engineering XVI
The present volume sets forth new contributions in areas of numerical analysis, computer science, scientific and industrial applications, and software development.
Domain Decomposition Methods in Science and Engineering
Domain decomposition is an active, interdisciplinary research area that is devoted to the development, analysis and implementation of coupling and decoupling strategies in mathematics, computational science, engineering and industry.This book special focus has been on numerical analysis, computational issues,complex heterogeneous problems, industrial problems, and software development.
Doing integrated history and philosophy of science : A case study of the origin of genetics
offers an integrated historical and philosophical examination of the origin of genetics. The author contends that an integrated HPS analysis helps us to have a better understanding of the history of genetics, and sheds light on some general issues in the philosophy of science. consists of three parts. It begins with historical problems, revisiting the significance of the work of Mendel, de Vries, and Weldon. Then it turns to integrated HPS problems, developing an exemplar-based analysis of the development and the progress in early genetics. Finally, it discusses philosophical problems: conceptual change, evidence, and theory choice.
