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Epigenetics and chromatin

This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility.

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Epidemiology of Drug Abuse

As the drug abuse epidemic evolves, so do the tools needed to understand and treat it. Accordingly, Epidemiology of Drug Abuse takes the long view, cogently outlining what the book calls "the natural history of drug abuse" and redefining its complex phenomena to reflect our present-day knowledge. Twenty-six eminent contributors discuss the state and future of the field, balancing the practical concerns involved in gathering drug abuse data with the ethics of using the information.

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Enzymes and drugs

Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.

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Enzyme-Catalyzed Synthesis of Polymers

New polymers have been developed and "old" polymers have been generated using novel synthetic strategies. This book contains seven chapters that cover in great deatail the use of enzymes to synthesize a range of polymers. It also makes use of a large number of examples to summarize the salient features of the enzymatic reactions and resulting polymeric properties.

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Enzyme-Based Organic Synthesis

In Enzyme-Based Organic Synthesis, expert chemist Dr. Cheanyeh Cheng delivers a comprehensive discussion of the principles, methods, and applications of enzymatic and microbial processes for organic synthesis. The book thoroughly explores this growing area of green synthetic organic chemistry, both in the context of academic research and industrial practice.

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Enzyme Biocatalysis : Principles and Applications

This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds.

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Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives

The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications.

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Environments for Multi-Agent Systems III ; 3rd International Workshop, E4MAS 2006, Hakodate, Japan, May 8, 2006, Selected Revised and Invited Papers

This book are organized in topical sections on models, architecture, and design, mediated interaction and stigmery, governing environment, and applications.

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Environments for Multi-Agent Systems II ; 2nd International Workshop, E4MAS 2005, Utrecht, The Netherlands, July 25, 2005, Selected Revised and Invited Papers

This book constitutes the thoroughly refereed post-proceedings of the Second International Workshop on Environments for Multiagent Systems, E4MAS 2005, held in July 2005. The 16 revised papers presented were carefully reviewed and selected from the lectures given at the workshop.

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Environmentally Friendly Coastal Protection ; Proceedings of the NATO Advanced Research Workshop on Environmentally Friendly Coastal Protection Structures, Varna, Bulgaria, 25-27 May 2004

Coast lines have been and are the central lines of civilization around the world with increasing pressure from both sides - the hinterland and the sea. This book features papers covering related aspects of Environmentally Friendly Coastal Structures - coast, engineering structures, water, sediments, ecosystems in their complicated interaction

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Environmental valuation with discrete choice experiments : Guidance on design, implementation and data analysis

This book offers up-to-date advice and practical guidance on how to undertake a discrete choice experiment as a tool for environmental valuation. It discusses crucial issues in designing, implementing and analysing choice experiments. Compiled by leading experts in the field, the book promotes discrete choice analysis in environmental valuation through a more solid scientific basis for research practice. Instead of providing strict guidelines, the book helps readers avoid common mistakes often found in applied work. It is based on the collective reflections of the scientific network of researchers using discrete choice modelling in the field of environmental valuation (www.envecho.com).

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Environmental Security in Harbors and Coastal Areas : Management Using Comparative Risk Assessment and Multi-Criteria Decision Analysis

This book explores the challenges facing coastal areas during the next few decades and the difficult decisions needed to prevent a repeat of the past. Establishing, maintaining or enhancing a sense of environmental security in different coastal regions and improving the management of critical infrastructure will require (i) matching human demands with available environmental resources; (ii) recognition of environmental security threats and infrastructure vulnerabilities; and, (iii) identification of the range of available options for preventing and/or minimizing natural disasters, technological failures, and/or terror actions. This book emphasizes beliefs that the convergence of seemingly disparate viewpoints and often uncertain and limited information is possible only by using one or more available risk assessment methodologies and decision-making tools such as multi-criteria decision analysis (MCDA).

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Environmental Security and Sustainable Land Use - with special reference to Central Asia

This book presents important aspects of environmental security and sustainable land use in general and in particular for Central Asia, i.e. the environmental consequences of climate change; sustainable land use and regional development; sustainable development in mountain and steppe regions; beyond borders: Transboundary Biosphere Reserve "Altai" as an approach for regional development; landscape planning as an integrative tool for sustainable development; challenges and threats for environmental stability in Central Asia. A final recommendation in the area of sustainable development and land use as well as the proceeding efforts towards the establishment of the Transboundary Biosphere Reserve "Altai" and the implementation of landscape planning were set in the book as some of the main results of the meeting.

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Environmental security and environmental management : The role of risk assessment ; Proceedings of the NATO Advanced Research Workhop on The Role of Risk Assessment in Environmental Security and Emergency Preparedness in the Mediterranean Region, held in Eilat, Israel, April 15-18, 2004

The concept of “environmental security” has emerged as one basis for understanding international conflicts. This phrase can mean a variety of things. It can signify security issues stemming from environmental concerns or conflicting needs, or it can mean that the environment is treated as a resource for the long term, and the question is what should be done today to preserve the quality of the environment in the future. In the same way that energy security is about ensuring access to energy for the long run, it can also mean that pressing environmental concerns create a situation where different countries and communities are forced to collaboratively design a unified response, even if cooperation is not generally in the logic of their relations. Over the last several years, the authors of this book and their colleagues have tried to demonstrate the power of risk assessment and decision analysis as valuable tools that decision makers should use for a broad range of environmental problems, including environmental security. Risk analysis is almost more a state of mind or a way of looking at problems than it is a kind of algorithm or a set of recipes. It projects a kind of rationality on problems and forces a certain degree of quantitative rigor, as opposed to the all too common tendency of making environmental recommendations based on anecdotal evidence.

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Environmental Role of Wetlands in Headwaters

Internationally, the wetlands of headwater and upland regions provide many valuable environmental services. This book moves towards a more comprehensive inventory of the benefits and costs of headwater wetlands. It evaluates the research that tries to understand the tolerances, exchanges, checks and balances within headwater landscapes and the downstream impacts of changes in wetlands. It employs case studies and reviews from 21 nations spanning Europe, Africa, Asia and the Americas. It explores the new policy frameworks, changes in land husbandry, new systems for community education, participatory processes and technological interventions required for the effective management of headwater wetlands and the full integration of wetlands (including newly constructed wetlands) into environmental management and planning. In the past, most research dealt with wetlands as isolated features, this book examines wetlands in their watershed management context.

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Environmental Policy Analyses : Learning from the Past for the Future - 25 Years of Research

The criteria used to select the fifteen contributions in this book were their impact on the scientific debate at the time of their publication, their validity for p- sent conceptualizations of policy analysis in the field of the environment, and their contribution to the development of policy analysis as a whole . Moreover, the selected contributions mainly focus on empirical appli- tions in the field of environmental policies or the interface between en- ronmental and non-environmental policies. Some have led to concrete p- icy recommendations of which most have been partly implemented since, This research also sometimes addressed regional political administrative arrangements leading to administrative reforms and new strategic directions of implementing agencies.

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Environmental Issues in Latin America and the Caribbean

This book is a non-technical interdisciplinary collection of 12 essays, each of which uses natural or social science methods. The essays analyze a representative set of environmental issues in Latin America and the Caribbean. They consider problems at international, regional, national, and local levels and examine current and historical environmental policy. The essays are organized according to theme and approach into five parts: -conservation challenges; -national policies, local communities, and rural development; -market mechanisms for protecting public goods; -public participation and environmental justice; -the effects of development policies on the environment. Contributors are researchers from Canada, Europe, Latin America, and the United States

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Environmental impact assessment of recycled wastes on surface and ground waters ; Vol.3 : Engineering modeling and sustainability

The state of the art of the impact assessment of recycled hazardous waste materials on surface and ground waters is presented. The topics include chemodynamics, toxicology, modeling and information systems. The book serves as a practical conceptual guide for those who have professional responsibility for the monitoring, design, management, or conduct of environmental impact assessment. It is believed that the book will prove useful to the reader who, regardless of disciplinary background, wants to examine in greater detail the kinds of interdisciplinary contributions to contemporary decision-making processes that characterize modern impact assessment project development.

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Environmental Impact Assessment of Recycled Wastes on Surface and Ground Waters ; Vol.2 : Risk analysis

The state of the art of the impact assessment of recycled hazardous waste materials on surface and ground waters is presented. The topics include chemodynamics, toxicology, modeling and information systems. The book serves as a practical conceptual guide for those who have professional responsibility for the monitoring, design, management, or conduct of environmental impact assessment. It is believed that the book will prove useful to the reader who, regardless of disciplinary background, wants to examine in greater detail the kinds of interdisciplinary contributions to contemporary decision-making processes that characterize modern impact assessment project development.

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Environmental Impact Assessment of Recycled Wastes on Surface and Ground Waters ; Vol.1 : Concepts, methodology and cemical analysis

The state of the art of the impact assessment of recycled hazardous waste materials on surface and ground waters is presented. The topics include chemodynamics, toxicology, modeling and information systems. Due to the wealth of information on this topic, the texts of T. Kassim (ed.): Environmental Impact Assessment are published in three separate volumes: vol. 1: Concepts, Methodology and Chemical Analysis; vol. 2: Risk Analysis and vol. 3: Engineering Modeling and Sustainability. The book serves as a practical conceptual guide for those who have professional responsibility for the monitoring, design, management, or conduct of environmental impact assessment. It is believed that the book will prove useful to the reader who, regardless of disciplinary background, wants to examine in greater detail the kinds of interdisciplinary contributions to contemporary decision-making processes that characterize modern impact assessment project development.

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