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Cancerimmunotherapies : Solid tumors and hematologic malignancies
Presents the clinical scope of cancer immunotherapeutic agents for solid tumors and Hematologic malignancies, elaborates on the scientific details of their modes of action, and presents the impact of these agents on oncology, patients and the broader healthcare system. At present, cancer immunotherapies fall broadly into three categories: immune checkpoint inhibitors (ICIs), adoptive T cell therapies, and cancer vaccines which have distinct mechanisms of action. Immune checkpoint inhibitors rely upon disrupting tumor antigen recognition as self by the immune system through inhibition of checkpoint molecules. Adoptive T cell therapies involve the engineering of T cells ex vivo to target and destroy tumor cells. The first part of this book will provide an overview of the discovery and mechanistic details of the technology. The second part will be devoted to elaborating on the clinical outcomes, successes and limitations for specific tumor subtypes, which includes both solid tumors and hematologic malignances for both pediatric and adult populations.
Cancer Prevention
This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions.
Cancer in the Arab World
Over the past few decades, the Arab world has witnessed a swift evolution in healthcare provision. Nonetheless, Arab countries have considerable variability in economic capabilities, resource allocation, and intellectual talent that inevitably reflect on access to modern cancer care and prevention. This book is authored by experts from the Arab world who provide vital information on cancer statistics and risk factors, available clinical care pathways and infrastructure, and prevention programs in their individual countries. The chapters also address specific challenges in each country and insights into future directions to achieve optimal care with conventional and novel diagnostics and therapies to keep up with the era of precision medicine.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer Chemotherapy in Clinical Practice
This book summarises the whole range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications.
Canadian Semantic Web
This book covers a variety of well known topics of interest to practitioners in industry and research scientists. The range of topics includes languages, tools and methodologies for the semantic Web, semantic Web-based ontology management and engineering, semantic Web services, practical applications of the semantic Web techniques, artificial intelligence methods and tools for the semantic Web, software agents on the semantic Web, visualization and modeling of the semantic Web. The goal of this book is to provide a state-of-the-art review of the research as well as to introduce topics of interest to experts.
Calibrating the Cosmos : How Cosmology Explains Our Big Bang Universe
Calibrating the Cosmos describes hard science, but is gently written. It explains in clear, non-mathematical language the measurements and the interpretation of the resulting data that have led to the current understanding of the origin, evolution and properties of our expanding Big Bang universe. Many people have a sketchy idea of the work of cosmologists, but Professor Levin’s experience in teaching both scientific and liberal arts students has enabled him to impart much of our current thinking without resorting to difficult mathematics. Theoretical concepts are emphasized, in particular the symmetries of homogeneity and isotropy enjoyed by our universe on the largest scales, how these symmetries lead to only one quantity being needed to describe the growth of the universe from its infancy to the present time, and how the so-called parameters of the universe are the ingredients used to construct the model universes to which ours – the real thing – is compared.
Calcolo stocastico per la finanza = Stochastic Calculation for Finance
Offers an introduction to the mathematical, probabilistic and numerical methods that are the basis of the models for the valuation of derivative instruments, such as options and futures, dealt with in modern financial markets. The book is aimed at readers with scientific training, wishing to develop skills in the field of stochastic calculus applied to finance.
Calcolo Scientifico : Esercizi e problemi risolti con MATLAB e Octave = Scientific computing : exercises and problems solved with MATLAB and Octave
For the short courses of the new system of the Faculties of Engineering and Sciences. It deals with all the typical topics of Numerical Mathematics, ranging from the problem of approximating a function, to the computation of its zeros, its derivatives and its definite integral up to the approximate solution of ordinary differential equations and limit problems.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
Cachexia and Wasting : A Modern Approach
Aim of the volume is to provide the best available evidence on the pathogenesis, clinical features and therapeutic approach of cachexia, and to facilitate the understanding of the complex yet unequivocal clinical role of this syndrome, that truly represents a disease, or, better still, a disease within other different diseases.
By its cover : Modern American book cover design
i JUDGING THE BOOK Books are a thing of beauty,but so are horse-drawn carriages. 1 DICK BRASS Vice President of Technology Development, Microsoft Is the printed book destined for eventual extinction? Is the thoughtfully designed book cover approaching obsolescence? The availability of ebooks has indeed increased, and print-on-demand technology will likely change the way books are marketed and purchased. But there is something special about the mass-produced book as an object– it is more than just a presentation of the ideas of an author.
Business processes : An archival science approach to collaborative decision making, records, and knowledge management
Collaborative decision making processes are a form of communication inside organizations. Their functioning can teach lessons for the design of electronic office systems. Those processes are open ended and therefore decide themselves on their form. Like oral deliberations which cannot be modelled in advance any open ended communication process needs means for common control over the further advancement and the ending of the process.The book is a reworked English version of a thesis for the official qualification for university professorship accepted by the German University of Administrative Sciences Speyer. Germany.
Business process management Workshops ; Vol. 4103 : BPM 2006 International Workshops, BPD, BPI, ENEI, GPWW, DPM, semantics4ws, Vienna, Austria, September 4-7, 2006, Proceedings
BPM 2006 was the fourth in a conference series that provides a forum for - searchers and practitioners in all areas of business process management. In c- junction with BPM 2006, a series of workshops were held. They were meant to facilitate the exchange of ideas and experiences between active researchers, and to stimulate discussions on new and emerging topics in line with the conference topics. We see the workshops as a necessary extension to the main conference. BPM has established itself rapidly as a high quality conference with a highly competitive selection process.
Business process management Workshops ; Vol. 3812 : BPM 2005 International Workshops, BPI, BPD, ENEI, BPRM, WSCOBPM, BPS, Nancy, France, September 5, 2005. Revised Selected Papers
Six parallel Business Process Management workshops were held on September 5th, 2005,The topics of the workshops ranged from fundamental process modeling primitives to the recently emerged field of Web service choreography and orchestration, rep- sented in the “Workshop on Business Processes and Services” and the “Workshop on Web Service Choreography and Orchestration;” a topic which intersects the research fields of business process management and Web services.
Business process management Workshops ; BPM 2007 International Workshops, BPI, BPD, CBP, ProHealth, RefMod, semantics4ws, Brisbane, Australia, September 24, 2007, Revised Selected Papers
This book constitutes the thoroughly refereed post-workshop proceedings of 6 internationl workshops held in Brisbane, Australia, in conjunction with the 5th International Conference on Business Process Management, BPM 2007, in September 2007.
Business process management ; Vol. 4102 : 4th International Conference, BPM 2006, Vienna, Austria, September 5-7, 2006, Proceedings
This book constitutes the refereed proceedings of the 4th International Conference on Business Process Management, BPM 2006. The book presents 20 revised full papers, 5 industrial papers, and 15 short papers together with an invited paper and the abstract of an invited talk. The papers are organized in topical sections on monitoring and mining, service composition, process models and languages, dynamic process management, Web service composition, and applied business process management.
Business process management ; Vol. 3649 ; 3rd International Conference, BPM 2005, Nancy, France, September 5-8, 2005, Proceedings
This volume contains the proceedings of the 3rd International Conference on Business Process Management (BPM 2005), organized by LORIA in Nancy, France, 2005. This year, BPM included several innovations with respect to previous e- tions, most notably the addition of an industrial program and of co-located workshops. This was the logical result of the signi?cant (and still growing) - dustrial interest in the area and of the broadening of the research communities working on BPM topics, includ Information Systems Applications (incl. Internet) / Information Storage and Retrieval / User Interfaces and Human Computer Interaction / Computers and Society / Management of Computing and Information Systems / IT in Business
Business process management ; 6th International Conference, BPM 2008, Milan, Italy, September 2-4, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th International Conference on Business Process Management, BPM 2008, held in Milan, Italy, in September 2008.
Business process management ; 5th International Conference, BPM 2007, Brisbane, Australia, September 24-28, 2007, Proceedings
This book includes business process maturity and performance, business process modeling, case studies, compliance and change, process configuration and execution, formal foundations of BPM, business process mining, and semantic issues in BPM.
