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Bioinformatics Using Computational Intelligence Paradigms

Bioinformatics as well as Computational Intelligence are undoubtedly remarkably fast growing fields of research and real-world applications with enormous potential for current and future developments. "Bioinformatics using Computational Intelligence Paradigms" contains recent theoretical approaches and guiding applications of biologically inspired information processing systems(Computational Intelligence) against the background of bioinformatics. This carefully edited monograph combines the latest results of Bioinformatics and Computational Intelligence and offers a promising cross-fertilisation and interdisciplinary work between these growing fields.

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Bioinformatics tools for pharmaceutical drug product development

Presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. And include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall.

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Bioinformatics technologies

Solving modern biological problems requires advanced computational methods. Bioinformatics evolved from the active interaction of two fast-developing disciplines, biology and information technology. The central issue of this emerging field is the transformation of often distributed and unstructured biological data into meaningful information. This book describes the application of well-established concepts and techniques from areas like data mining, machine learning, database technologies, and visualization techniques to problems like protein data analysis, genome analysis and sequence databases. Chen has collected contributions from leading researchers in each area. The chapters can be read independently, as each offers a complete overview of its specific area, or, combined, this monograph is a comprehensive treatment that will appeal to students, researchers, and R&D professionals in industry who need a state-of-the-art introduction into this challenging and exciting young field.

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Bioinformatics research and development ; 2nd International Conference, BIRD 2008 Vienna, Austria, July 7-9, 2008 Proceedings

This book constitutes the refereed proceedings of the Second International Bioinformatics Research and Development Conference, BIRD 2008, held in Vienna, Austria in July 2008.

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Bioinformatics research and development ; 1st International Conference, BIRD 2007, Berlin, Germany, March 12-14, 2007, Proceedings

This volume covers a wide range of topics related to bioinformatics like microarray data, genomics, single nucleotide polymorphism, sequence analysis, systems biology, medical applications, proteomics, information systems.

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Bioinformatics research and applications ; 3rd International Symposium,ISBRA 2007, Atlanta, GA, USA, May 7-10, 2007, Proceedings

This book including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

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Bioinformatics research and applications : 4th International Symposium, ISBRA 2008, Atlanta, GA, USA, May 6-9, 2008. Proceedings

This book constitutes the refereed proceedings of the Fourth International Symposium on Bioinformatics Research and Applications, ISBRA 2008, held in Atlanta, GA, USA in May 2008.

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Bioinformatics for oral cancer : Current insights and advances

Offering a deep dive into the multifaceted landscape of oral cancer research and bioinformatics. Readers will uncover a wealth of knowledge, starting with foundational chapters introducing bioinformatics and establishing the backdrop of oral cancer. The book then progresses into the realm of diagnostic biomarkers, revealing cutting-edge methodologies for their identification in the context of oral cancer. The book’s keen focus extends to gene expression profiles and the intricacies of gene sequencing in the context of oral cancer progression.

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Bioinformatics and systems biology : Collaborative research and resources

Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.

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Bioinformatics

In this textbook present mathematical models in bioinformatics and they describe the biological problems that inspire the computer science tools used to handle the enormous data sets involved. The first part of the book covers the mathematical and computational methods, while the practical applications are presented in the second part. The mathematical presentation is descriptive and avoids unnecessary formalism, and yet remains clear and precise. Emphasis is laid on motivation through biological problems and cross applications. Each of the four chapters in the first part is accompanied by exercises and problems to support an understanding of the techniques presented. Each of the six chapters of the second part is devoted to some specific application domain: sequence alignment, molecular phylogenetics and coalescence theory, genomics, proteomics, RNA, and DNA microarrays. Each chapter concludes with a problems and projects section, to deepen the reader's understanding and to allow for the design of derived methods. Many of the projects involve publicly available software and/or Web-based bioinformatics depositories. Finally, the book closes with a thorough bibliography, reaching from classic research results to very recent findings, providing many pointers for future research.Overall, this volume is ideally suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on its mathematical and computer science background.

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Bioimaging in Neurodegeneration

offers both the physician and researcher a critical survey of the best new technologies for studying neurodegeneration, as well as describing their optimal use in the diagnosis and treatment of specific neurodegenerative diseases

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Bioimage Data Analysis Workflows

This book provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python.

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Bioethics and the Holocaust : A Comprehensive Study in How the Holocaust Continues to Shape the Ethics of Health, Medicine and Human Rights

This book offers a framework for understanding how the Holocaust has shaped and continues to shape medical ethics, health policy, and questions related to human rights around the world. The field of bioethics continues to face questions of social and medical controversy that have their roots in the lessons of the Holocaust, such as debates over beginning-of-life and medical genetics, end-of-life matters such as medical aid in dying, the development of ethical codes and regulations to guide human subject research, and human rights abuses in vulnerable populations. As the only example of medically sanctioned genocide in history, and one that used medicine and science to fundamentally undermine human dignity and the moral foundation of society, the Holocaust provides an invaluable framework for exploring current issues in bioethics and society today. This book, therefore, is of great value to all current and future ethicists, medical practitioners and policymakers – as well as laypeople.

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Bioethics across the globe : Rebirthing bioethics

This book addresses a variety of issues relating to bioethics, in order to initiate cross-cultural dialogue. Beginning with the history, it introduces various views on bioethics, based on specific experiences from Japan. It describes how Japan has been confronted with Western bioethics and the ethical issues new to this modern age, and how it has found its foothold as it decides where it stands on these issues. In the last chapter, the author proposes discarding the overarching term ‘Global Bioethics’ in favor of the new term, ‘Bioethics Across the Globe (BAG)’, which carries a more universal connotation.

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Bioengineering in cell and tissue research

This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering.

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Bioenergetics : Energy conservation and conversion

The present book addresses fundamental questions of biological energy transformation and conservation, with a focus on those processes which can now be understood on a structural basis.Current knowledge of selected examples of the biological energy conservation machinery such as cellular oxygen respiration, light-driven energy converters, and fermentation is reviewed. The machinery is highly variable, particularly that within microorganisms, but all of these devices universally rely on one unique underlying physico-chemical principle. The book is a rich source for specialists interested in recent developments in bioenergetics research and novices in the field alike.

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Bioelectromagnetics current concepts : The mechanisms of the biological effect of extremely high power pulses

Proceedings of the NATO Advanced Research Workshop on The Mechanisms of the Biological Effect on Extra High Power Pulses (EHPP), Yerevan, Armenia 3 - 5 March 2005

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Biodiversity in Enclosed Seas and Artificial Marine Habitats ; Proceedings of the 39th European Marine Biology Symposium, held in Genoa, Italy, 21-24 July 2004

The main themes of the Symposium were biodiversity in enclosed and semi-enclosed seas and artificial habitats, and the restoration of degraded systems. These themes are highly relevant today both from a basic scientific point of view and from an applied approach. The papers dealing with the first theme represent current research and concerns about marine biodiversity in enclosed seas and will have wide appeal to all those interested in understanding and preserving the biodiversity of the seas and in particular of the Mediterranean and Black Seas. The papers in the second theme represent a synthesis of up-to-date knowledge on artificial habitats and how they can contribute to protection of coastal marine ecosystems, to enhancement of species diversity and biological resources and to restoration of degraded marine environments.

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Biodiversity Conservation and Phylogenetic Systematics : Preserving our evolutionary heritage in an extinction crisis

This book brings an updated state of the art of phylogenetic diversity in conservation biology. Nineteen chapters written by scientists from research institutions of fourteen countries demonstrate that approaches for preserving the evolutionary heritage are now very tuned into human impacts and sustainability issues. The questions, methods and applications around which it is organized show the importance of phylogenetic diversity in avoiding biodiversity losses in the present extinction crisis. They touch important points such as the way we value phylogenetic diversity, the importance of thinking at a much wider sample of the Tree of Life, the choice of adequate measures. In methods section, new solutions, such as dealing with abundances, sampling effort, or with information coming from conflicting phylogenetic trees are provided. Application section includes study cases of different groups of organi

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Biocombinatorial approaches for drug finding

Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource

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