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General Relativity

this book is a short and concise exposition of the central ideas of general relativity. Although the original audience was made up of mathematics students, the focus is on the chain of reasoning that leads to the relativistic theory from the analysis of distance and time measurements in the presence of gravity, rather than on the underlying mathematical structure. The geometric ideas - which are central to the understanding of the nature of gravity - are introduced in parallel with the development of the theory, the emphasis being on laying bare how one is led to pseudo-Riemannian geometry through a natural process of reconciliation of special relativity with the equivalence principle.

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General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology

Brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.

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General principles of law : the role of the judiciary

Examines the role played by domestic and international judges in the “flexibilization” of legal systems through general principles. It features revised papers that were presented at the Annual Conference of the European-American Consortium for Legal Education, held at the University of Parma.The second section contains studies on the role of general principles in selected legal systems, including International Law, European Union Law as well as Common Law systems.

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General Methods and Overviews, Lung Carcinoma and Prostate Carcinoma

This is the first book that discusses the subjects of diagnosis, therapy, therapy assessment, and prognosis of lung and prostate cancer in one single volume. This second volume in the series Methods of Cancer Diagnosis, Therapy and Prognosis presents a comprehensive treatise on all aspects of Lung and Prostate cancer, including diagnosis, treatments and prognosis.

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General Equilibrium and Welfare Economics : An Introduction

A good basic understanding of general equilibrium theory is a fundamental and indispensable background for advanced work in virtually any sub-field of economics; and a thorough understanding of the methods of welfare economics, particularly in a general equilibrium context, is indispensable for investigators undertaking applied policy analysis. This book addresses these needs and requirements by emphasizing the basic underpinnings of general equilibrium and welfare economics. In particular, the theory of choice, which is fundamental to both areas, is developed in a very comprehensive and rigorous fashion. Moreover, extensive use is made of examples, both of the simple type intended to bolster the student’s understanding of the basic concepts, and those illustrating the application of the material to field areas in economics.

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Gene Therapy of Autoimmune Disease

Gene Therapy of Autoimmune Diseases comprehensively reviews research in gene therapy for autoimmune diseases with viral or non-viral vectors. Gene therapy offers the possibility of long-term, continuous delivery of a wide variety of immunosuppressive, anti-inflammatory, or tolerance-inducing agents. Moreover, highly specific genetically modified cells can be produced. This book discusses the most promising avenues in this exciting new field.

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Gene Therapy for Cancer

The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.

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Gene Expression Programming : Mathematical Modeling by an Artificial Intelligence

This monograph provides all the implementation details of GEP so that anyone with elementary programming skills will be able to implement it themselves. The book also includes a self-contained introduction to this new exciting field of computational intelligence, including several new algorithms for decision tree induction, data mining, classifier systems, function finding, polynomial induction, times series prediction, evolution of linking functions, automatically defined functions, parameter optimization, logic synthesis, combinatorial optimization, and complete neural network induction. The book also discusses some important and controversial evolutionary topics that might be refreshing to both evolutionary computer scientists and biologists.

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Gene Expression and Regulation

This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. Presented in the following five sections, this book covers a full spectrum of topics: The History; The Machinery; The Regulators; The Genome; and Special Topics. The Machinery section covers the transcriptional apparatus and general transcription factors. The Regulators section examines selected gene-specific transcription factors important to regulating gene expression. The Genome section covers issues relevant to the behavior of the genome in relation to gene regulation. The Special Topics section discusses several selected topics ranging from bacterial and plant gene expression to DNA topology and interference RNA. The book’s focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.

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Gene drives at tipping points : Precautionary technology assessment and governance of new approaches to genetically modify animal and plant populations

This book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.

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Genders in the Life Course : Demographic Issues

Treats the topic of gender and demographic behaviour during the life course in a comprehensive fashion. It covers a lot of ground, from the age at first intercourse over union formation and dissolution, fertility, migration, ageing, to excess male mortality, comparing genders behaviour and its determinants. It reports new findings of empirical research, mostly based on data from a number of European countries, making a good use of the Family and Fertility surveys and other international data base.

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Gender, Health and Ageing : European Perspectives on Life Course, Health Issues and Social Challenges

The objective of this book is to provide an overview of gender, health and ageing. Important theoretical concepts, such as life course and "Lebenslagen" in old age, or differences in men's health, are introduced. It is increasingly important to build a European basis of knowledge, to conduct discussions on European research findings, and to develop European research frameworks. In this volume, central theoretical debates on gender impacts on life course and old-age health, and vital issues of health research in the context of gender and old age are introduced. Specific aspects, such as the impact of gender and age on cardiovascular health, elder abuse and mental health, or care between gender relations, gender roles and gender constructs, are pointed out.

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Gender Innovation and Migration in Switzerland

This book analyses migration and its relation to socio-political transformation in Switzerland. It addresses how migration has made new forms of life possible and shows how this process generated gender innovation in different fields: the changing division of work, the establishment of a nursery infrastructure, access to higher education for women, and the struggle for female suffrage. Seeing society through the lens of migration alters the perspective from which our past and thus our present is told—and our future imagined.

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Gender Equality Programmers in Higher Education : International Perspectives

For the last twenty years gender equality has been on the agenda of national higher education policies both within Europe and beyond it.the authors of this book analyse under which circumstances equality programmes are successful. In order to develop a deeper understanding of the mechanisms of and barriers to gender equality in higher education this book presents comparative studies and research focusing on the development of gender equality policies in different countries, as well as studies on the conditions for implementing policies, changes in strategies and the evaluation of gender equality programmes.

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Gender Differences in Computer and Information Literacy : An In-depth Analysis of Data from ICILS

When computer technology was first introduced in schools, there was a prevailing belief that information and communication technologies were ‘boys’ toys’; boys were assumed to have more positive attitudes toward using computer technologies. As computer technologies have become more established throughout societies, gender gaps in students’ computer and information literacy appear to be closing, although studies into gender differences remain sparse.

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Gender Designs IT : Construction and Deconstruction of Information Society Technology

The book not only offers a gender analysis of information society technologies, it also shows practical examples of how IT can be different. A gender perspective on IT design can serve as an eye-opener for what tends to be overlooked and left out. It yields innovative ideas and high quality software systems that may empower a large diversity of users for an active participation in our information society.

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Gender and the judiciary in Africa: from obscurity to parity

Addresses the important issue of the increasing numbers and varied roles of women judges and justices, as judiciaries evolve across the continent.Scholars of law, gender politics and African politics provide overviews of recent developments in gender and the judiciary in nine African countries that represent north.

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Gender and migration : IMISCOE short reader

This short reader offers a critical review of the debates on the transformation of migration and gendered mobilities primarily in Europe, though also engaging in wider theoretical insights. Building on empirical case studies and grounded in an analytical framework that incorporates both men and women, masculinities, sexualities and wider intersectional insights, this reader provides an accessible overview of conceptual developments and methodological shifts and their implications for a gendered understanding of migration in the past 30 years. It explores different and emerging approaches in major areas, such as: gendered labour markets across diverse sectors beyond domestic and care work to include skilled sectors of social reproduction; the significance of families in migration and transnational families.

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Gathering Hopewell : Society, Ritual and Ritual Interaction

In this book, twenty-one researchers in interwoven efforts immerse themselves and the reader in this vibrant archaeological record in order to richly reconstruct the faces, actions, and motivations Hopewellian people in their social and ritual life. Using a personalized and locally contextualized approach, the authors explore Hopewellian leadership, systems of social ranking and prestige, animal-totemic clan organization, kinship structures, sodalities, gender, community organizations, strategies of intercommunity alliance, and interregional travels for power questing, pilgrimage, healing, tutelage, and acquiring rituals.

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Gastrointestinal malignancies

Details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices.

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