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Applications and innovations in intelligent systems XII ; Proceedings of AI-2004, the Twenty-fourth SGAI International Conference on Innhovative Techniques and Applications of Artificial Intelligence

The papers in this volume are the refereed application papers presented at AI-2004, the Twenty-fourth SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence, held in Cambridge 2004. The papers present new and innovative developments in the field, divided into sections on Synthesis and Prediction, Scheduling and Search, Diagnosis and Monitoring, Classification and Design, and Analysis and Evaluation. This is the twelth volume in the Applications and Innovations series. The series serves as a key reference on the use of AI Technology to enable organisations to solve complex problems and gain significant business benefits. The Technical Stream papers are published as a companion volume under the title Research and Development in Intelligent Systems XXI.

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Application of microbes in environmental and microbial biotechnology

Discusses the innovative approaches and investigation strategies, as well as provides a broad spectrum of the cutting-edge research on the processing, properties and technological developments of microbial products and their applications. Microbes finds very important applications in our lives including industries and food processing. They are widely used in the fermentation of beverages, processing of dairy products, production of pharmaceuticals, chemicals, enzymes, proteins and biomaterials / conversion of biomass into fuel, fuel cell technology, health and environmental sectors. Some of these products are produced commercially, while others are potentially valuable in biotechnology. Microorganisms are considered invaluable in research as model organisms. This is a useful compilation for students and researchers in microbiology, biotechnology and chemical industries.

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Application of computational electromagnetics techniques and artificial intelligence in the engineering

Introduces the latest developments in electromagnetic computing and artificial intelligence technology. Artificial intelligence technology can be applied to the modeling, analysis, and optimization design of microwave equipment, solving the routing problem of self-organizing networks in small unmanned aerial vehicle systems, calculating the radiation characteristics of antenna arrays on large electrical platforms, analyzing the impact of electromagnetic wave coupling on electronic devices, simulating the field distribution characteristics of electronic devices, and so on. With the help of artificial intelligence, designers can more conveniently, quickly, and accurately solve engineering problems.

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Application and Theory of Petri Nets 2002 ; 23rd International Conference, ICATPN 2002, Adelaide, Australia, June 24-30, 2002. Proceedings

This book constitutes the refereed proceedings of the 23rd International Conference on Application and Theory of Petri Nets, ICATPN 2002, held in Adelaide, Australia, in June 2002. The 18 regular papers and one tool presentation presented together with six invited paper were carefully reviewed and selected from 45 submissions. All current issues on research and development of Petri nets are addressed, in particular concurrent systems analysis, model validation, business process management, reactive systems, workflow processes, wireless transaction protocols.

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Apoptotic pathways as targets for novel therapies in cancer and other diseases

The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients.

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Anxiety in health behaviors and physical illness

While the links between physical illness and depression have been well-documented and analyzed, little has been made of the data relating physical illness to anxiety—until now. Anxiety in Health Behavior and Physical Illness explores complex relationships between medical and anxiety pathology on the theoretical, research, and practical fronts. Over forty experts examine reciprocal roles of anxiety and medical illness as causal or exacerbating factors in each other’s onset and development, describe forms of anxiety typical to major disease entities, discuss common health behaviors as they impact anxiety, recast anxiety disorders as chronic illness, and identify patients for whom new forms of treatment may be warranted.

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Antiviral drug discovery and development

Summarizes antiviral drug design and discovery approaches Provides the latest update in the field of antiviral therapeutics Includes antiviral research of coronaviruses

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Anti-Spam Measures : Analysis and Design

The goal of this book is the methodical analysis of the potential, limitations, advantages, and drawbacks of anti-spam measures. These determine to which extent the measures can contribute to the reduction of spam in the long run. The range of considered anti-spam measures includes legislative, organizational, behavioral and technological ones. Furthermore, the conceptual development and analysis of an infrastructural email framework that features such a complementary application, is pointed out. The technological and organizational facets, the framework is analyzed twofold: its theoretical effectiveness is assessed with the aid of the formal model mentioned above, its storage and traffic requirements are analyzed quantitatively.

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Anti-Microbial Resistance in Global Perspective

This book provides an accessible introduction to the mechanics of international development and global health text for policy-makers and students across a wide range of disciplines.

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Antimalarial natural products

Begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type.

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Anti-fragile ICT Systems

Introduces a novel approach to the design and operation of large ICT systems. It views the technical solutions and their stakeholders as complex adaptive systems and argues that traditional risk analyses cannot predict all future incidents with major impacts. To avoid unacceptable events, it is necessary to establish and operate anti-fragile ICT systems that limit the impact of all incidents, and which learn from small-impact incidents how to function increasingly well in changing environments. The book applies four design principles and one operational principle to achieve anti-fragility for different classes of incidents. It discusses how systems can achieve high availability, prevent malware epidemics, and detect anomalies. Analyses of Netflix’s media streaming solution, Norwegian telecom infrastructures, e-government platforms, and Numenta’s anomaly detection software show that cloud computing is essential to achieving anti-fragility for classes of events with negative impacts.

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Antifouling Paint Biocides

This volume describes the state-of-the-art advances regarding antifouling paint biocides and provides thorough evaluation of research and information on major topics such as occurrence and levels, environmental fate, analytical techniques and methods for the monitoring and control, environmental modeling, ecotoxicological effects and risk assessment placing emphasis on the knowledge acquired over the last 10 years. The contamination of the aquatic environment by antifouling compounds has been a topic of increasing importance during the last few years. The major classes of antifouling active biocides are discussed including the old-fashioned organotin compounds, the modern organic booster biocides and the promising naturally occurring antifoulant products. Therefore, the reader will get a balanced view of this developing field. Chapters were written by leading experts in their field who critically surveyed all the major areas of progress. This volume is an important resource and can constitute a good grounding in the field of antifouling paint biocides.

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Antidiabetic plants for drug discovery pharmacology, secondary metabolite profiling, and ingredients with insulin mimetic activity

Takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs. Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology.

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Anticancer activity in heterocyclic organic structures : A pathway to novel drug development : Part 1

New Directions in Organic & Biological Chemistry, explores the development of cancer therapeutics, focusing on molecular chemistry and advanced drug design approaches. Written by experts in theoretical chemistry and molecular chemistry, they bridge the gap between theoretical chemistry, molecular biology, and drug development. In Part I, they focus on the fundamental properties of heterocyclic compounds and innovative methodologies being employed to enhance therapeutic potential. By exploring various classes of heterocyclic compounds and diverse anticancer mechanisms.

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Antibiotic Drug Resistance

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases.

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Antiangiogenic Agents in Cancer Therapy

Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.

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Anorexia nervosa and mood-enhancing foods

Anorexia nervosa (AN) is a serious mental illness characterized by failure to maintain normal weight and by overvalued ideas about the importance of body shape and weight. This study aims to discuss Anorexia nervosa and understand the pathophysiology to successfully fight this enigmatic illness and present the goal of the treatment for individuals with AN. The bi-directional influences between emotion and food consumption are discussed. Finally, we have searched in Future Directions and Treatment development of AN.

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Anomalies of the Developing Dentition : A Clinical Guide to Diagnosis and Management

This book is an up-to-date, succinct, and easily accessible reference on the diverse anomalies that may arise in the developing dentition, including those relating to crown size and shape, tooth formation, tooth eruption, tooth number, and enamel and dentin.

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Animals and the shaping of modern medicine : One health and its histories

This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and reveals that what we think of as ‘human’ medicine was in fact deeply zoological.Each chapter analyses an important episode in which animals changed and were changed by medicine. Ranging across the animal inhabitants of Britain’s zoos, sick sheep on Scottish farms, unproductive livestock in developing countries, and the tapeworms of California and Beirut, they illuminate the multi-species dimensions of modern medicine and its rich historical connections with biology, zoology, agriculture and veterinary medicine. The modern movement for One Health – whose history is also analyzed – is therefore revealed as just the latest attempt to improve health by working across species and disciplines.

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Animal Models of T Cell-Mediated Skin Diseases

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

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