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The Molecular Genetics of Lung Cancer
Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.
The Missing Links in Teacher Education Design : Developing a Multi-linked Conceptual Framework
This ground-breaking, internationally oriented book brings together a number of excellent contributions on new directions in the design of teacher education programs. Moreover, the ideas are connected through a clear and stimulating conceptual framework that has the potential to guide effective innovation in the field.Teacher education program design demands a conceptualization built on strong interlinked foundations so that coursework and practice complement each another as a dynamic whole. Hoban offers an outstanding explication of exactly that through his Missing Links in Teacher Education. In so doing he offers a way of enhancing the quality of teacher education programs for those scholars passionate about, and committed to the work of teaching and learning about teaching.
The Method of Intrinsic Scaling : A Systematic Approach to Regularity for Degenerate and Singular PDEs
This set of lectures, which had its origin in a mini course delivered at the Summer Program of IMPA (Rio de Janeiro), is an introduction to intrinsic scaling, a powerful method in the analysis of degenerate and singular PDEs. In the first part, the theory is presented from scratch for the model case of the degenerate p-Laplace equation. This approach brings to light what is really essential in the method, leaving aside technical refinements needed to deal with more general equations, and is entirely self-contained. The second part deals with three applications of the theory to relevant models arising from flows in porous media and phase transitions. The aim is to convince the reader of the strength of the method as a systematic approach to regularity for this important class of equations.
The Metaphysics of Science : An Account of Modern Science in Terms of Principles, Laws and Theories
The roots of this work lie in my earlier book, Scientific Progress, which first appeared in 1981. One of its topics, the distinction - tween scientific laws and theories, is there treated with reference to the same distinction as drawn by N. R. Campbell in his Physics: The Elements. Shortly after completing Scientific Progress, I read Rom Harré’s The Principles of Scientific Thinking, in which the concept of theory is even more clearly delineated than in Campbell, being directly connected to the notion of a model – as it was in my book. In subsequent considerations regarding science, Harré’s work thus - came my main source of inspiration with regard to theories, while Campbell’s remained my main source with respect to empirical laws. Around the same time I also read William Whewell’s Philosophy of the Inductive Sciences.
The Mediterranean Sea
This volume deals with several aspects of the chemical contamination of the Mediterranean Sea and its health. After a description of the general physical and socio-economic context, exploration of processes governing the fate of chemicals, the budget of both inorganic and organic major and preoccupant contaminants and a description of new tools to study the impact of pollution on the Mediterranean Sea are discussed. The book serves as a reference source for the chemical aspects of the Mediterranean Sea for students and scientists and a practical guide for those who have professional responsibility for the management and operation of environmental impact assessment programmes.
The Mathematica GuideBook for Symbolics
"The Mathematica GuideBook for Symbolics"deals with Mathematica's symbolic mathematical capabilities. Structural and mathematical operations on single and systems of polynomials are fundamental to many symbolic calculations and they are covered in considerable detail. The solution of equations and differential equations, as well as the classical calculus operations (differentiation, integration, summation, series expansion, limits) are exhaustively treated.
The Mathematica GuideBook for Numerics
Mathematica is today's most advanced technical computing system, featuring a rich programming environment, two-and three-dimensional graphics capabilities and hundreds of sophisticated, powerful programming and mathematical functions using state-of-the-art algorithms. Combined with a user-friendly interface and a complete mathematical typesetting system, Mathematica offers an intuitive, easy-to-handle environment of great power and utility.The available types of arithmetic (machine, high-precision, and interval) are introduced, discussed, and put to use. Fundamental numerical operations, such as compiling programs, fast Fourier transforms, minimization, numerical solution of equations, ordinary/partial differential equations are analyzed in detail and are applied to a large number of examples in the main text and solutions to the exercises.
The Magnetospheric Cusps : Structure and Dynamics
This collection of papers will address the question "What is the Magnetospheric Cusp?" and what is its role in the coupling of the solar wind to the magnetosphere as well as its role in the processes of particle transport and energization within the magnetosphere. The cusps have traditionally been described as narrow funnel-shaped regions that provide a focus of the Chapman-Ferraro currents that flow on the magnetopause, a boundary between the cavity dominated by the geomagnetic field (i.e., the magnetosphere) and the external region of the interplanetary medium. Measurements from a number of recent satellite programs have shown that the cusp is not confined to a narrow region near local noon but appears to encompass a large portion of the dayside high-latitude magnetosphere and it appears that the cusp is a major source region for the production of energetic charged particles for the magnetosphere.
The Longleaf Pine Ecosystem : Ecology, Silviculture, and Restoration
The longleaf pine ecosystem, once one of the most extensive ecosystems in North America, is now among the most threatened. Over the past few centuries, land clearing, logging, fire suppression, and the encroachment of more aggressive plants have led to an overwhelming decrease in the ecosystem’s size, to approximately 2.2% of its original coverage. Despite this devastation, the range of the longleaf still extends from Virginia to Texas. Through the combined efforts of organizations such as the USDA Forest Service, the Longleaf Alliance, and the Nature Conservancy, extensive programs to conserve, restore, and manage the ecosystem are currently underway.
The Kaiser Wilhelm Institute for Anthropology, Human Heredity, and Eugenics, 1927–1945: Crossing Boundaries
The volume at hand traces the history of the Kaiser Wilhelm Institute for Anthropology, Human Heredity and Eugenics between democracy and dictatorship. Special attention is turned to the transformation of the research program, the institute’s integration into the national and international science panorama, and its relationship to the ruling power as well as its interconnection to the political crimes of Nazi Germany.
The IT Measurement Compendium : Estimating and Benchmarking Success with Functional Size Measurement
The first step towards success in a software project is to ensure a professional setup. This includes a metrics-based formal estimation process to ensure a solid foundation for project planning. Accurate estimates require quantitative measurements, ideally tool based. In addition, software project managers must also monitor and update these estimates during the project’s lifecycle to control progress and assess possible risks.
The International Space Station : Building for the Future
A comprehensive, highly readable account of complex, technical, political and human endeavor and a worthy successor to Creating the International Space Station (Springer Praxis, January 2002) by David Harland and John Catchpole. This volume details for the first time the construction and occupation of the International Space Station from 2002 through to 2008, when it should reach American “Core Complete”.
The Integration of Phonetic Knowledge in Speech Technology
Continued progress in Speech Technology in the face of ever-increasing demands on the performance levels of applications is a challenge to the whole speech and language science community. Robust recognition and understanding of spontaneous speech in varied environments, good comprehensibility and naturalness of expressive speech synthesis are goals that cannot be achieved without a change of paradigm. This book argues for interdisciplinary communication and cooperation in problem-solving in general, and discusses the interaction between speech and language engineering and phonetics in particular. With a number of reports on innovative speech technology research as well as more theoretical discussions, it addresses the practical, scientific and sometimes the philosophical problems that stand in the way of cross-disciplinary collaboration and illuminates some of the many possible ways forward.
The impact of dividend policy on stock market value : an applied study at Damascus securities exchange
Tests the impact of dividend policy on stock market value for a sample consisted of (10) listed companies in DSE for the period between years (2017-2021). Dividend policy data were extracted from the financial reports for the sample of the research they were divided into three groups: SPSS program was used to make descriptive statistic study and linear regression to test the hypothesis...
The Impact of COVID-19 on the Syrian banks
Aims to study the impact of the new Coronavirus on Syrian banks. By analyzing banks’ disclosures about their data, some concepts about the Coronavirus pandemic and the historical sequence of the emergence of the virus were present. Then a theoretical study on the financial statements of banks to studying the impact of Coronavirus on local banks through the statistical programs and T-test and the correlation relationship that was cover within the applied aspect of the research. As the variables were compare for five Syrian banks before and after the announcement of infection inside Syria. To measure the results and the impact of Corona on financial performance, and the study concluded that there is an impact of the Coronavirus on Syrian banks despite the policies and procedure taken by the Monetary Council and the Central Bank of Syria to mitigate the impact of the virus.
The Immune Synapse as a Novel Target for Therapy
The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell–APC junction. It plays an essential role in the control and nature of the immune response.In recent years several approaches have been developed to reprogram the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as those targeting the lymphocyte co-receptor, costimulatory and adhesion molecules (CD3, CD4, CD40L, CTLA4-Ig, LFA-1), or altered peptide ligands have been shown capable of inducing immune tolerance in transplantation, autoimmunity and allergy. This volume discusses the progress in the field, from basic science to clinical trials, and the major mechanisms involved. It is of interest to clinicians and researchers working in this area.
The human hippocampus : Functional anatomy, vascularization and serial sections with MRI
This book offers a precise description of the anatomy of human hippocampus in view of neurosurgical progress and the wealth of medical imaging methods available. A survey of the current concepts explains the functions of the hippocampus and describes its external and internal vascularisation. Head sections and magnetic resonance images complete this comprehensive view of human hippocampal anatomy. It will be of interest to neuroscientists and, in particular, to neurosurgeons, neuroradiologists and neurologists.
The Greening of Architecture : A Critical History and Survey of Contemporary Sustainable Architecture and Urban Design
Offers a comprehensive critical history and analysis of the greening of architecture through accumulative reduction of negative environmental effects caused by buildings, urban designs and settlements. Describing the progressive development of green architecture from 1960 to 2010, it illustrates how it is ever evolving and ameliorated through alterations in form, technology, materials and use and it examines different places worldwide that represent a diversity of cultural and climatic contexts. The book is divided into seven chapters: with an overview of the environmental issues and the nature of green architecture in response to them, followed by an historic perspective of the pioneering evolution of green technology and architectural integration over the past five decades, and finally, providing the intransigent and culturally pervasive current examples within a wide range of geographic territories. The greening of architecture is seen as an evolutionary process that is informed by significant world events,
The greening of architecture : A critical history and survey of contemporary sustainable architecture and urban design
Contemporary architecture, and the culture it reflects dependent as it is on fossil fuels, has contributed to the cause and necessity of a burgeoning green process that emerged over the past half century. This text is the first to offer a comprehensive critical history and analysis of the greening of architecture through accumulative reduction of negative environmental effects caused by buildings, urban designs and settlements. Describing the progressive development of green architecture from 1960 to 2010, it illustrates how it is ever evolving and ameliorated through alterations in form, tech.
The Geometry of the Word Problem for Finitely Generated Groups
The advanced course on The geometry of the word problem for fnitely presented groups was held July 5-15, 2005, at the Centre de Recerca Matematica ̀ in B- laterra (Barcelona). It was aimed at young researchersand recent graduates int- ested in geometricapproachesto grouptheory,in particular,to the wordproblem. Three eight-hour lecture series were delivered and are the origin of these notes. There were also problem sessions and eight contributed talks. The course was the closing activity of a research program on The geometry of the word problem, held during the academic year 2004-05 .
