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Delivery of drugs ; Vol.2 : Expectations and realities of multifunctional drug delivery systems
Examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects.This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders.
Deep Learning, Machine Learning and IoT in Biomedical and Health Informatics : Techniques and Applications
Examines and demonstrates state-of-the-art approaches for IoT and Machine Learning based biomedical and health related applications. This book aims to provide computational methods for accumulating, updating and changing knowledge in intelligent systems and particularly learning mechanisms that help us to induce knowledge from the data. It is helpful in cases where direct algorithmic solutions are unavailable, there is lack of formal models, or the knowledge about the application domain is inadequately defined. In the future IoT has the impending capability to change the way we work and live. These computing methods also play a significant role in design and optimization in diverse engineering disciplines. With the influence and the development of the IoT concept, the need for AI (artificial intelligence) techniques has become more significant than ever.
Decentralisation and Privatisation in Education : The Role of the State
The book examines the overall interplay between privatisation, decentralisation and the role of the state. The authors draw upon recent studies in the areas of decentralisation, privatisation and the role of the state in education. By referring to Bourdieu’s call for critical policy analysts to engage in a ‘critical sociology’ of their own contexts of practice, and poststructuralist and postmodernist pedagogy, this collection of book chapters demonstrate how central discourses surrounding the debate of privatisation, decentralisation and the role of the state are formed in the contexts of dominant ideology, power, and culturally and historically derived perceptions and practices.
Data science in theory and practice : Techniques for big data analytics and complex data sets
Delivers a comprehensive treatment of the mathematical and statistical models useful for analyzing data sets arising in various disciplines, like banking, finance, health care, bioinformatics, security, education, and social services. Written in five parts, the book examines some of the most commonly used and fundamental mathematical and statistical concepts that form the basis of data science. The authors go on to analyze various data transformation techniques useful for extracting information from raw data, long memory behavior, and predictive modeling. Readers will also learn from topics like: Analyses of foundational theoretical subjects, including the history of data science, matrix algebra and random vectors, and multivariate analysis A comprehensive examination of time series forecasting, including the different components of time series and transformations to achieve stationarity Introductions to both the R and Python programming languages, including basic data types and sample manipulations for both languages An exploration of algorithms, including how to write one and how to perform an asymptotic analysis A comprehensive discussion of several techniques for analyzing and predicting complex data sets
Data mining : Concepts, models, methods, and algorithms ; 3rd ed.
Presents the latest techniques for analyzing and extracting information from large amounts of data in high-dimensional data spaces. Explores big data and cloud computing Examines deep learning Includes information on convolutional neural networks (CNN) Offers reinforcement learning Contains semi-supervised learning and S3VM Reviews model evaluation for unbalanced data
Curves and Surfaces for Computer Graphics
Computer graphics is important in many areas including engineering design, architecture, education, and computer art and animation. This book examines a wide array of current methods used in creating real-looking objects in the computer, one of the main aims of computer graphics.
Curriculum Reform in the European Schools : Towards a 21st Century Vision
Examines the modern role of the European School system within the European Union, at a time when the global economy demands a new vision for contemporary education. The European schools are currently in a state of crisis: their 60-year-old tradition of bilingual and multilingual education is being strained by rapid EU expansion and the removal of English speaking teachers as a result of Brexit. Their tried and tested model of mathematics and science education has rapidly been overtaken by new developments in pedagogy and assessment research, while recruitment and retention of students and teachers has become increasingly fraught as European member states review what they are, and what they are not, prepared to fund. The authors draw on original and empirical research to assess the European Schools’ place in a new Europe where the entire post-war European Project is potentially at risk. This well-researched volume will be of interest to practitioners working in European schools as well as students and scholars of EU politics and international education.
Cultural Convergence : The Dublin Gate Theatre, 1928–1960
Based on extensive archival research, this book examines the poetics and politics of the Dublin Gate Theatre (est. 1928) over the first three decades of its existence, discussing some of its remarkable productions in the comparative contexts of avant-garde theatre, Hollywood cinema, popular culture, and the development of Irish-language theatre, respectively. The overarching objective is to consider the output of the Gate in terms of cultural convergence – the dynamics of exchange, interaction, and acculturation that reveal the workings of transnational infrastructures.
Crypto-Finance, Law and Regulation : Governing an Emerging Ecosystem
Explores the emergence of a decentralised and disintermediated crypto-market and investigates the way in which it can transform the financial markets. It examines three components of the financial market – technology, finance, and the law – and shows how their interrelationship dictates the structure of a crypto-market. It focuses on regulators’ enforcement policies and their jurisdiction over crypto-finance operators and participants. The book also discusses the latest developments in crypto-finance, and the advantages and disadvantages of crypto-currency as an alternative payment product. It also investigates how such a decentralised crypto-finance system can provide access to finance, promote a shared economy, and allow access to justice.
Crisis and Legitimacy in Atlantic American Narratives of Piracy: 1678-1865
This book, Crisis and Legitimacy in Atlantic American Narratives of Piracy: 1678-1865, examines literary and visual representations of piracy beginning with A.O. Exquemelin’s 1678 Buccaneers of America and ending at the onset of the US-American Civil War.
Creative Model Construction in Scientists and Students : The Role of Imagery, Analogy, and Mental Simulation
How do scientists use analogies and other processes to break away from old theories and generate new ones? This book documents such methods through the analysis of video tapes of scientifically trained experts thinking aloud while working on unfamiliar problems. Some aspects of creative scientific thinking are difficult to explain, such as the power of analogies, the use of physical intuition, and the enigmatic ability to learn from thought experiments. The book examines the hypothesis that these processes are based on imagistic mental simulation as an underlying mechanism. This allows the analysis of insight ("Aha!") episodes of creative theory formation.
Courts, politics and constitutional law : judicialization of politics and politicization of the judiciary
Examines how the judicialization of politics, and the politicization of courts, affect representative democracy, rule of law and separation of powers. This volume critically assesses the phenomena of judicialization of politics and politicization of the judiciary. It explores the rising impact of courts on key constitutional principles, such as democracy and separation of powers, which is paralleled by increasing criticism of this influence from both liberal and illiberal perspectives. The book also addresses the challenges to rule of law as a principle, preconditioned on independent and powerful courts, which are triggered by both democratic backsliding and the mushrooming of populist constitutionalism and illiberal constitutional regimes.
Counter-Terrorism Policing : Community, Cohesion and Security
This book charts these opportunities and challenges through unprecedented access to the police and diverse communities in Australian regional and metropolitan contexts. It locates these developments in an international comparison with like jurisdictions in the US, UK, and Canada and in light of former conflicts in Northern Ireland and South Africa. It examines the nature and impact of counter-terrorism on policing, diverse communities, legislation and policy and on the media. The book concludes by posing questions for the future of counter-terrorism policing in liberal democracies.
Corporate Performance Management : ARIS in Practice
Corporate Performance Management (CPM) is a basic approach which examines the relationship between corporate performance and process optimization. How to successfully introduce CPM in practice is demonstrated through project reports from E.ON, British Telecom, Credit Suisse and Vodafone among others. The methods and tools presented here guarantee a continuous and automated monitoring of the corporate performance and enable Business Process Excellence to be permanently established in the company by company-internal and company-external benchmarking. The articles in this book focus on the use of the ARIS Controlling Platform developed by IDS Scheer.
Corporate Control and Enterprise Reform in China : An Econometric Analysis of Block Share Trades
This study sheds light on the efficiency of corporate control allocation in Chinese listed firms. Using a panel data set for the period 1996 to 2006, it examines the frequency, causes and consequences of changes in corporate control. The results indicate that poorly performing firms are the predominant targets of control changes; shareholder and creditor control generally act as a complement for changes in control. Following the change in ownership there is a substantial amount of corporate restructuring and an improvement in operating performance. Significant differences in these dimensions emerge, however, between State and private transfers of control. The findings not only provide insights into the motives and constraints of the key players involved in governance practices in China; but they also contain useful implications for other emerging markets around the world that have weak legal systems and weak property rights protection.
Coordination models and languages ; 9th International Conference, COORDINATION 2007, Paphos, Cyprus, June 6-8, 2007, Proceedings
he volume examines how to increase modularity, simplify reasoning, and ultimately enhance today's software development by exploring the spectrum of languages, middleware, services, and algorithms. The papers are organized in topical sections on middleware, logic programming, formal approaches, concurrency, components and services, as well as MANets.
Contracting and safety : Exploring outsourcing practices in high-hazard industries
This book examines the increase in outsourcing, contracting and subcontracting as ways of organising work. It explores the impact of these employment arrangements on public safety, particularly when they are linked to complex supply networks in a range of engineering industries including oil and gas, nuclear power and aviation.
Contemporary issues in sustainable finance : Exploring performance, impact measurement and financial inclusion
This book sheds light on contemporary challenges in sustainable finance, addressing two key perspectives: measurement and performance, and products and business models. In particular, the volume examines theoretically and empirically the relations between business models and non-financial impact, both environmental and social.
Contemporary endodontics for children and adolescents
Describes pulp therapy from a holistic approach that highlights new developments in the field. Readers will find updates on the formation, structure and function of the dental pulp revealed by the latest single-cell technologies, and discussions on carious lesions and their impact on the pulp. The book examines clinical considerations in the decision to perform pulp treatment and emphasizes the need to integrate pupal diagnostics with patient-dependent factors such as behavior management and pulpal pain mechanisms. The second part of the book includes comprehensive descriptions of current treatments for each type of caries-inflicted tooth damage, from selective caries removal through direct pulp capping, pulpotomy, pulpectomy and root canal therapy for primary dentition to direct pulp capping and endodontic treatment of young permanent teeth.
Consumer Packaging Strategy : Localisation in Asian Markets
Illustrates how packaging as a marketing tool is more than simply changing the label or translating the brand into vernacular language. It examines how different packaging elements (e.g. information, imagery, packaging type) can help to communicate product values to Asian consumers.
