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Modern Actuarial Risk Theory : Using R
"The book gives a comprehensive survey of non-life insurance mathematics. … Originally written for use with the actuarial science programs at the Universities of Amsterdam and Leuven, it is now in use at many other universities as well as for the non-academic actuarial education program organized by the Dutch Actuarial Society. The methods presented can not only be used in non-life insurance, but also in other branches of actuarial science, as well as in actuarial practice. (Pavel Stoynov, Zentralblatt MATH, Vol. 1148, 2008). This book gives an introduction to non-life insurance mathematics. … Throughout the book, the software R is used for the implementation of the techniques presented. One finds also many exercises with hints for their solution in an appendix.
Models, Mysteries, and Magic of Molecules
Molecular behaviour, which is no less than magical, holds the key to the understanding, not only of chemistry, but of all biology and of life itself. It is a mystery why molecular behaviour should remain poorly understood and why the authoritative theories of physics have produced no more than superficial models to elucidate this vital issue. This book explores the common ground to guide chemists, biologists, crystallographers, spectroscopists and theorists into a deeper recognition of their individual relevance towards painting a holistic picture of scientific endeavour. This effort to stimulate interest in multidisciplinary research is rare, if not unique.
Models, Methods and Tools for Product Service Design : The Manutelligence Project
This book summarizes research being pursued within the Manutelligence project, the goal of which is to help enterprises develop smart, social and flexible products with high value added services. Manutelligence has improved Product and Service Design by developing suitable models and methods, and connecting them through a modular, collaborative and secure ICT Platform. The use of real data collected in real time by Internet of Things (IoT) technologies underpins the design of product-service systems and makes it possible to monitor them throughout their life cycle. Available data allows costs and sustainability issues to be more accurately measured and simulated in the form of Life Cycle Cost (LCC) and Life Cycle Assessment (LCA). Analysing data from IoT systems and sharing LCC and LCA information via the ICT Platform can help to accelerate the design of product-service systems, reduce costs and better understand customer needs. Industrial partners involved in Manutelligence provide a clear overview of the project's outcomes, and demonstrate how its technological solutions can be used to improve the design of product-service systems and the management of product-service life cycles.
Models and methods for management science
Introduces systems science as an entry point to present a basic introduction to research models and methods in management science (operation research). This textbook selects the classic quantitative models and methods as well as rich cases and detailed examples, which are suitable for students with a certain management and economics knowledge for further study, and helps to develop the abilities of using the basic models in real life
Modelling and simulation of discrete-event systems
Allows engineers to study and analyze complex systems. Discrete-event system (DES)-M&S is used in modern management, industrial engineering, computer science, and the military. As computer speeds and memory capacity increase, so DES-M&S tools become more powerful and more widely used in solving real-life problems.
Modeling biological systems : Principles and applications
This extensively revised second edition of Modeling Biological Systems: Principles and Applications describes the essentials of creating and analyzing mathematical and computer simulation models for advanced undergraduates and graduate students. It offers a comprehensive understanding of the underlying principle, as well as details and equations applicable to a wide variety of biological systems and disciplines. Students will acquire from this text the tools necessary to produce their own models. The text contains two major sections: Principles and Applications. The first section discusses the principles of biological systems with a thorough description of the essential modeling activities of formulation, implementation, validation, and analysis. These activities are illustrated by a set of example models taken from recent and classical literature, chosen for their breadth of coverage and current timeliness. The new edition updates extensively many of these topics, especially quantitative model formulation, validation and model discrimination using information theory measures and Bayesian probability, and stability analysis and non-dimensionalization.
Modèles aléatoires : Applications aux sciences de l'ingénieur et du vivant = Random models : Applications to engineering and life sciences
The aim is to show how random models are used to analyse and solve a great variety of engineering issues. It is written in language accessible to practitioners and students in engineering, the physical sciences, the life sciences or management.
Model Based Inference in the Life Sciences : A Primer on Evidence
The abstract concept of "information" can be quantified and this has led to many important advances in the analysis of data in the empirical sciences. This text focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The fundamental science question relates to the empirical evidence for hypotheses in this set—a formal strength of evidence. Kullback-Leibler information is the information lost when a model is used to approximate full reality. Hirotugu Akaike found a link between K-L information (a cornerstone of information theory) and the maximized log-likelihood (a cornerstone of mathematical statistics). This combination has become the basis for a new paradigm in model based inference. The text advocates formal inference from all the hypotheses/models in the a priori set—multimodel inference.
Mobility Aware Technologies and Applications ; 2nd International Workshop, MATA 2005, Montreal, Canada, October 17 -- 19, 2005, Proceedings
The beginning of the twenty-first century is characterized by global markets, and the mobility of people is becoming an important fact of life. Consequently, the mobile user is demanding appropriate technical solutions to make use of customized information and communication services. In this context the notion of next-generation networks (NGNs), which are driven by the convergence of the entertainment sector, the mobile Internet, and fixed/mobile telecommunications, is emerging. Such NGNs are aggregating a variety of different access networks and supporting the seamless connection of an open set of end-user devices, and due to the adoption of an all-IP network paradigm they enable a much better integration of voice and data services. Coincidently the buzzword ‘fixed mobile convergence’ (FMC) describes the current trend towards providing common services across fixed and mobile networks resulting in the medium term in the full integration of fixed and mobile telecommunication networks. The adoption of appropriate middleware technologies and the provision of - called service delivery platforms driven by the ongoing innovation in the field of information technologies provides today the technical foundation for supporting terminal, personal and service mobility and thus the implementation of real seamless information and communication services. Furthermore, users are nowadays looking, in light of an omnipresent service environment, for a much higher degree of customization and context awareness in the services they use. The papers in this volume look at these enabling mobility-aware technologies and their use for implementing mobility-aware and context-aware applications.
Mobile health technologies for ambient assisted living and healthcare
The use of telemedicine and mobile devices is growing, and sensors might aid in creating creative solutions. Developing these solutions is crucial for monitoring senior citizens, lifestyles, and medical procedures. The development of assistive technology for various users to follow sports and other activities is strongly tied to this study area. Data protection is crucial, and the development of these solutions for medical uses should be verified. The security and privacy of the information may be tied to other recognized research projects for their acceptability. ICT research has considerably improved quality of life and has fully assimilated all citizens into society through medical rehabilitation and assistive technology. The technologies and research fields that influence medical informatics include databases, networking, graphical user interfaces, data mining, machine learning, intelligent decision support systems, and specialized programming languages.
Mitochondria : The Dynamic Organelle
This volume discusses the death pathways that are initiated by the mitochondria. Novel therapeutic interventions are proposed which interfere with the death cascades, thereby rescuing the cell from mitochondria-linked apoptosis and necrotic oncosis.
Misleading marketing communication : Assessing the impact of potentially deceptive food labelling on consumer behaviour
Presenting four complementary experimental studies targeting recurrent grey-zone scenarios on the Danish food market, the book illustrates the potential of the so-called ShopTrip test paradigm which simulates and registers real-life e-shopping behaviour as it unfolds while yielding new types of data against which opposing assessments of potential misleadingness can be matched. The results are discussed in the light of possible paths of theoretical explanation and implications for future regulative practices, including companies’ self-regulation.
Misbehaving Proteins : Protein (Mis)Folding, Aggregation, and Stability
Misfoldedaggregatedproteinoncewasconsideredasinterestingasyesterday’strash—a bothersome by-product of important and productive activities, to be disposed of and forgotten as quickly as possible. Yesterday’s trash has become today’s focus of cons- erable scienti?c interest for at least two reasons: (1) protein aggregates are at the core of a number of chronic degenerative diseases such as Alzheimer’s disease, and (2) - gregation poses signi?cant obstacles to the manufacture of safe, ef?cacious, and stable protein products. As interest in protein misfolding, aggregation, and stability has soared beyond the core group of traditional protein-folding scientists, and as substantial scienti?c progress in understanding and controlling protein misfolding has been achieved, the need to summarize the state of the art became manifest. Although there are many excellent texts and edited collections on protein structure and folding, these volumes tend to relegate protein misfolding and aggregation to a minor role. Review articles and books focused on the biological role of protein aggregates in diseases have been published recently.
Mild Stress and Healthy Aging : Applying hormesis in aging research and interventions
Stress is a double edged sword. Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can improve various biological parameters, including severe stress tolerance, health span and longevity. Mild stress-induced hormesis is potentially a powerful tool in gerontological research and interventions. This book brings together some of the world leaders in this area of research who present a critical analysis of the ongoing research with respect to the effects and mechanisms of action of various types of mild stress, such as irradiation, heat, physical exercise, hypergravity, pro-oxidants and nutritional components, on a variety of biological systems ranging from fruitflies to human cells and bodies. Their separate chapters and a final collective chapter open up a whole new world of possibilities for future research in aging, successful aging, and health span extension.
Migrants and Expats : The Swiss Migration and Mobility Nexus
This book provides insight on current patterns of migration in Switzerland, which fall along a continuum from long-term and permanent to more temporary and fluid. These patterns are shaped by the interplay of legal norms, economic drivers and societal factors. The various dimensions of this Migration-Mobility Nexus are investigated by means of newly collected survey data: the Migration-Mobility Survey. The book covers different aspects of life in the host country, including the family dimension, the labour market and political participation as well as social integration. The book also takes into account the chronological dimension of migration by considering the migrants’ arrival, their stay, and their expectations regarding return.
Mid-Infrared Coherent Sources and Applications
Coherent sources of mid-infrared (mid-IR) radiation are of great interest for a wide range of scienti?c and technological applications from spectroscopy and frequency metrology to information technology, industrial process control, pho- chemistry, photobiology and photomedicine. The mid-IR spectrum, which may be de?ned as wavelengths beyond ?2µm, covers important atmospheric windows, and numerous molecular gases, toxic agents, air, water, and soil pollutants, c- ponents of human breath, and several explosive agents have strong absorption ?ngerprints in this region. The development of practical coherent solid-state sources in the mid-IR can thus provide indispensable tools for a variety of - plications in environmental monitoring and pollution control, detection of water and soil contaminants, food quality control, agriculture and life sciences, and n- invasive disease diagnosis and therapy through breath analysis.
Micropropagation methods in temporary immersion systems
Presents vital techniques for the commercial micropropagation of plants. It explores numerous micropropagation protocols in different types of temporary immersion systems for plant species with agricultural, medicinal, ornamental, and forestry interest, detailing the type of bioreactor and the optimal parameters necessary to guarantee obtaining the largest number of commercial propagules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Microorganisms in the deterioration and preservation of cultural heritage
This book offers a comprehensive overview of the role and potential of microorganisms in the degradation and preservation of cultural materials (e.g. stone, metals, graphic documents, textiles, paintings, glass, etc.).
Microorganisms and Bioterrorism
The purpose of this book is to bring together, in a single volume, the most up-to-date information concerning microbes with potential as bioterrorist weapons. The primary audience includes microbiologists, including bacteriologists, virologists and mycologists, in academia, government laboratories and research institutes at the forefront of studies concerning microbes which have potential as bioterrorist weapons, public health physicians and researchers and scientists who must be trained to deal with bioterrorist attacks as well as laboratory investigators who must identify and characterize these microorganisms from the environment and from possibly infected patients.
Micronutrients and macronutrients as nutraceuticals
Explains in detail the properties of micronutrients and macronutrients and their diverse uses as nutraceuticals for their beneficial properties, such as their antioxidant activity and immunity-boosting properties and how they can be incorporated into the human diet for optimum health, for growing beneficial bacteria in the gut, and inhibition of pathogens. Interestingly, the authors look at how disease-promoting habits often unfold in childhood, even prenatally, and employing nutrigenomics early on goes a long way toward curbing these chronic diseases later on in life.
