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Capacity options for revenue management : Theory and applications in the air cargo industry
Hellermann addresses in his dissertation one of the most interesting - pects of this evolution for OR/MS, the parallel development of long-term and short-term markets for capacity and output, accompanied by a range of option and ?xed-commitment (i. e. , forward) contracts as the basic mec- nisms supporting transactions. This has been a fascinating topic for OR/MS research because it builds on the powerful framework of real options, while connecting directly to key operations decisions (capacity planning, network design, staf?ng, routing, maintenance, and so forth) of the equipment and technologies whose output is the focus of contracts.
Capacity Building and Training for Female Social workers at NGOs in Syria : The Case of Child Rights Association
The purpose of this dissertation is to build the capacity of female volunteer supervisors and staff to have a positive impact on the individual and society, building the community for the long term. The importance of capacity building for female supervisors in NGOs enhance the skills and competencies and capacities of local people and communities in developing societies so that they can overcome the reasons for their suffering. Organizational capacity building is used by NGOs and governments to guide their internal development and activities.
Cancer vaccination and challenges Vol.2 : delivery strategies for cancer vaccine and immunotherapy in the management of various carcinomas
Covers delivery strategies of cancer vaccines for the management of various forms of carcinoma, examining the prospects of delivering immuno-oncology therapies, focusing specifically on effective drug delivery strategies for the treatment of lung, prostate, and pancreatic carcinomas.
Cancer vaccination and challenges Vol.1 : strategies for therapeutic cancer vaccine development
Deals with different strategies of cancer vaccine development, focusing on techniques for the development of therapeutic cancer vaccines and the roles of tumor antigens, proteins/peptides, microbial genes, and stem cells for the development of vaccines for cancer management.
Cancer Stem Cells : Novel Concepts and Prospects for Tumor Therapy
This book describes the recent developments in the emerging field of cancer stem cells. Their possible impact for the identification of novel treatment paradigms for cancer are discussed. The book will mainly be of interest to scientists and clinicians involved in cancer research, or to students wishing to enter into this area.
Cancer Prevention
This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions.
Cancer immunotherapy
Defining Cancer as a disease in which some of the body's cells grow uncontrollably and spread to other parts of the body, making it an enormous medical and economic burden accounting for 9.6 million deaths in 2018. Cancer treatments were being introduced for a long time. The development of specific therapies to treat cancer really depends on the continued discovery of the molecular changes that lead to the malignant progression of human cancers. More and more drugs are being developed to block cancer pathways that lead to impaired growth and survival of cancer cells. In this dissertation, the concept of cellular and immunotherapy of cancer will be discussed briefly, taking into considerations the mechanisms of action, the advantages, challenges and drawbacks of the different types of monoclonal antibodies and CAR T-Cell therapy.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Campbell biology : Concepts and connections ; 10th global ed.
An innovative learning experience that addresses how studentslearn today Campbell Biology: Concepts & Connections continuesto introduce pedagogical developments that create an innovative learningexperience and motivate students not only to learn, but also interact withbiology
Calixarenes in the Nanoworld
Calixarenes have been widely exploited in all areas of supramolecular chemistry over the past three decades and many recent developments have concerned their applications in the production of chemical entities with the dimensions of nanometres, as in "nanochemistry".Calixarenes in the Nanoworld Relates calixarenes to nanochemistry – key information for industries engaged in the production of high-tech materials. Provides a timely review of both what is known and the exciting prospects provided by calixarenes, Contains several review articles which define the importance of calixarenes as reagents in nanochemistry.
Calculus of one variable
Aimed at first-year undergraduates in mathematics and the physical sciences, the only prerequisites are basic algebra, coordinate geometry and the beginnings of differentiation as covered in school. The transition from school to university mathematics is addressed by means of a systematic development of important classes of techniques, and through careful discussion of the basic definitions and some of the theorems of calculus, with proofs where appropriate, but stopping short of the rigour involved in Real Analysis.The influence of technology on the learning and teaching of mathematics is recognised through the use of the computer algebra and graphical package MAPLE to illustrate many of the ideas.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
By its cover : Modern American book cover design
i JUDGING THE BOOK Books are a thing of beauty,but so are horse-drawn carriages. 1 DICK BRASS Vice President of Technology Development, Microsoft Is the printed book destined for eventual extinction? Is the thoughtfully designed book cover approaching obsolescence? The availability of ebooks has indeed increased, and print-on-demand technology will likely change the way books are marketed and purchased. But there is something special about the mass-produced book as an object– it is more than just a presentation of the ideas of an author.
Business Success in China
In this book practitioners of international companies are offered valuable insights and lessons from established and successful managers, academics and consultants.
Business process management ; Vol. 3649 ; 3rd International Conference, BPM 2005, Nancy, France, September 5-8, 2005, Proceedings
This volume contains the proceedings of the 3rd International Conference on Business Process Management (BPM 2005), organized by LORIA in Nancy, France, 2005. This year, BPM included several innovations with respect to previous e- tions, most notably the addition of an industrial program and of co-located workshops. This was the logical result of the signi?cant (and still growing) - dustrial interest in the area and of the broadening of the research communities working on BPM topics, includ Information Systems Applications (incl. Internet) / Information Storage and Retrieval / User Interfaces and Human Computer Interaction / Computers and Society / Management of Computing and Information Systems / IT in Business
Business process management ; 6th International Conference, BPM 2008, Milan, Italy, September 2-4, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th International Conference on Business Process Management, BPM 2008, held in Milan, Italy, in September 2008.
Business partner management : Successfully managing external and internal business relationships
Provides a structured, industry-independent and at the same time practical insight into all types of business partnerships. Both relationships with external business partners and internal partnerships with colleagues and employees are considered in depth. The focus is on people as partner and individual with interests and goals. The comparison to private partnerships is quite intentional and illustrates the explanations. Findings from brain research, learning and cooperation are also included.
Business modeling and software design ; 10th International Symposium, BMSD 2020, Berlin, Germany, July 6-8, 2020, Proceedings
This book constitutes the refereed proceedings of the 10th International Symposium on Business Modeling and Software Design, BMSD 2020, which took place in Berlin, Germany, in July 2020. BMSD is a leading international forum that brings together researchers and practitioners interested in business modeling and its relation to software design. Particular areas of interest are: Business Processes and Enterprise Engineering; Business Models and Requirements; Business Models and Services; Business Models and Software; Information Systems Architectures and Paradigms; Data Aspects in Business Modeling and Software Development; Blockchain-Based Business Models and Information Systems; IoT and Implications for Enterprise Information Systems.
