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Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegenerative diseases.
Genomics-assisted crop improvement ; Vol.2 : Genomics applications in crops
Genomics research has great potential to revolutionize the discipline of plant breeding. This two-volume set provides a critical assessment of genomics tools and approaches for crop breeding. Volume 2, entitled "Genomics Applications in Crops", compiles crop-specific studies that summarize both the achievements and limitations of genomics research for crop improvement.
Genomics-assisted crop improvement ; Vol.1 : Genomics approaches and platforms
Genomics research has great potential to revolutionize the discipline of plant breeding. This two-volume set provides a critical assessment of genomics tools and approaches for crop breeding. Volume 1, entitled "Genomics Approaches and Platforms", illustrates state-of-the-art genomics approaches and platforms presently available for crop improvement.
Genomics of Tropical Crop Plants
Genomics of Tropical Crop Plants summarizes recent progress on genomic research, including the development of molecular markers, genomic and cDNA libraries, expressed sequence tags (ESTs), genetic and physical maps, gene expression profiles, and whole genome sequences for 20 tropical crop plants. It offers background information about the evolutionary origin and environments of tropical crop species, international programs that are addressing the needs of tropical agriculture, and the potential for new technologies to increase the productivity and value of tropical crops. This book provides new dimensions to growing information concerning temperate crops and their morphology, physiology, and parallel evolution in diverse plant lineages.
Genomics of Disease
Genomics of Disease is the 24th volume in the Stadler Genetics Symposium series published by Springer, which has, over many years, served as a comprehensive collection of current trends and hot topics in the field of genetics. The current volume summarizes recent progress in our attempts to characterize the genomics of plant and animal diseases. Authoritative analytical reviews are specialized to be attractive to professional researchers, teachers, and students, while also being appealing to a wider audience of scientists in related disciplines. Genomics of Disease offers essential reference material for any scientist or teacher working in the fields of plant and animal diseases. Coverage of key areas of both animal and plant disease is a unique feature of this volume and one that allows direct comparisons between the systems. All academics, scientists, and industry professionals that desire to take advantage of the most up-to-date information on the continuously emerging and expanding field of the genomics of plant and animal diseases will find it an invaluable resource.
Genomic intelligence : Metagenomics and artificial intelligence
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. Provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental.
Genomic Imprinting
Genomic imprinting refers to a recently discovered phenomenon in which the expression pattern of an allele depends on whether that allele was inherited from the mother or the father. This difference in expression strategy correlates with differences in the epigenetic state of the two alleles. The goal of this book is neither to provide a basic introduction to imprinting, nor to provide a comprehensive survey of the current state of the field (which would necessarily span multiple books). Rather, the book covers on some of the more recent advances, with the goal of drawing attention to some of the emerging subtleties and complexities associated with imprinted genes.
Genomes and Genomics of Nitrogen-fixing Organisms
Inthe book the first section organism based and should review our current knowledge of the genomes of nitrogen-fixing organisms and what these nucleotide sequences tell us. The second section should then be technology based. It should review what technologies are available to mine the data inherent in the nucleotide sequences and how they are now being used to produce gene-function data from differential gene expression.
Genome Mapping and Genomics in Fishes and Aquatic Animals
The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world.This volume summarizes the first era of genomic studies of aquaculture species, in which the tools and resources necessary to support whole-genome sequencing were developed. These tools will enhance efforts toward selective breeding of aquaculture species. Included in this volume are summaries of work on salmonids, cyprinids, catfish, tilapias, European sea bass, Japanese flounder, shrimps and oysters.
Genome Mapping and Genomics in Arthropods
Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world.Insects and other arthropods, the largest group of animals in number of species, have global impact on agriculture, industry, human health and environment. They are of particular economic importance for food production as pollinators, for natural products like silk and also as pests and parasites. Arthropods covered in this volume include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.
Genome integrity : Facets and perspectives
The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.
Genome instability in cancer development
Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain hereditary tumours, but they also set the stage for the development of anti-cancer drugs that specifically target activated oncogenes.
Genome Exploitation : Data Mining the Genome
Data Mining the Genomes, is the 23rd volume of the Stadler Symposia series published by Springer, which have served over many years as a comprehensive collection of current trends and emerging hot topics in the field of genetics. Data Mining the Genomes summarizes the progress in bioinformatics and computational biology in data mining the vast amount of exciting information emerging from studies of plant and animal genomes, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines.
Genome editing in neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Génetique statistique = Statistical genetics
Presents the main statistical tools useful in genetics: significance tests, analysis methods based on the likelihood function, EM algorithm, modeling, analysis of variance, hierarchical classifications, multiple comparisons, etc. All of them shed light on a number of biological phenomena such as carcinogenesis, population genetics, Hardy-Weinberg equilibrium, natural selection, mutations, heredity, coalescence processes, and even evolution. This book is intended for mathematicians and biologists alike. Written with a great concern for clarity, it is also accessible to non-specialists who will be able, thanks to it, to strengthen their theoretical base and above all to develop their know-how through very concrete applications.
Genetics of Adaptation
What is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Genetics and regulation of nitrogen fixation in free-Living bacteria
This book is the second volume of a seven-volume series, which covers all fields of research related to nitrogen fixation - from basic studies through applied aspects to environmental impacts. Volume II provides a comprehensive and detailed source of information concerning the genetics and regulation of biological nitrogen fixation in free-living prokaryotes.
Genetics and Genomics of Soybean
The book covers recent progress on genome research in soybeans, including the genetic map with classical, RFLP, SSR and SNP markers; genomic and cDNA libraries, functional genomics platforms (e.g., cDNA, Affymetrix and oligonucleotide based DNA microarrays); physical maps, and the efforts to fully sequence the genome. Given the pending release of the soybean genome sequence, through the efforts of the Department of Energy’s Joint Genome Institute, this book will stand as a critical source of information on soybean.
Genetic rogramming ; Vol. 3447 : 8th European conference, EuroGP 2005, Lausanne, Switzerland, March 30-April 1, 2005, Proceedings
In this volume we present the contributions for the 18th European Conference on Genetic Programming (EuroGP 2005). The conference took place from 30 March to 1 April in Lausanne, Switzerland. EuroGP is a well-established conf- ence and the only one exclusively devoted to genetic programming. All previous proceedings were published by Springer in the LNCS series. From the outset, EuroGP has been co-located with the EvoWorkshops focusing on applications of evolutionary computation. Since 2004, EvoCOP, the conference on evolutionary combinatorial optimization, has also been co-located with EuroGP, making this year’s combined events one of the largest dedicated to evolutionary computation in Europe. Genetic programming (GP) is evolutionary computation that solves complex problems or tasks by evolving and adapting a population of computer programs, using Darwinian evolution and Mendelian genetics as its sources of inspiration. Some of the 34 papers included in these proceedings address foundational and theoretical issues and there is also a wide variety of papers dealing with di?erent application areas, such as computer science, engineering, language processing, biology and computational design, demonstrating that GP is a powerful and practical problem-solving paradigm.
Genetic Programming Theory and Practice V
Genetic Programming Theory and Practice V was developed from the fifth workshop at the University of Michigan’s Center for the Study of Complex Systems to facilitate the exchange of ideas and information related to the rapidly advancing field of Genetic Programming (GP). Contributions from the foremost international researchers and practitioners in the GP arena examine the similarities and differences between theoretical and empirical results on real-world problems. The text explores the synergy between theory and practice, producing a comprehensive view of the state of the art in GP application.
