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Bioinformatics and the cell : Modern computational approaches in genomics, proteomics and transcriptomics
"Xuhua Xia’s Bioinformatics and the Cell is a welcome addition to the bourgeoning field of bioinformatics text books. Xia stakes out a too-often neglected middle ground in bioinformatics by presenting a work that emphasizes methods’ biological utility without eschewing algorithmic formalism. Readers will find a well-rounded presentation of bioinformatics techniques employed in genomics, transcriptomics and proteomics – unified throughout by the common theme of molecular evolution."
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Bioinformatics
In this textbook present mathematical models in bioinformatics and they describe the biological problems that inspire the computer science tools used to handle the enormous data sets involved. The first part of the book covers the mathematical and computational methods, while the practical applications are presented in the second part. The mathematical presentation is descriptive and avoids unnecessary formalism, and yet remains clear and precise. Emphasis is laid on motivation through biological problems and cross applications. Each of the four chapters in the first part is accompanied by exercises and problems to support an understanding of the techniques presented. Each of the six chapters of the second part is devoted to some specific application domain: sequence alignment, molecular phylogenetics and coalescence theory, genomics, proteomics, RNA, and DNA microarrays. Each chapter concludes with a problems and projects section, to deepen the reader's understanding and to allow for the design of derived methods. Many of the projects involve publicly available software and/or Web-based bioinformatics depositories. Finally, the book closes with a thorough bibliography, reaching from classic research results to very recent findings, providing many pointers for future research.Overall, this volume is ideally suited for a senior undergraduate or graduate course on bioinformatics, with a strong focus on its mathematical and computer science background.
Bioimage Data Analysis Workflows
This book provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python.
Biogeography, Time, and Place : Distributions, Barriers, and Islands
Biogeography considers the distribution of biological units over a wide range of scales. The units range from genotypes, populations and species to families and higher taxa. Processes can be local, such as the isolation on islands due to sea-level fluctuations, or large-scale tectonic processes that separates continents and creates oceans. In all processes time is an important factor and by combining data on recent patterns with paleontological data the understanding of the distribution of extant taxa can be improved. This volume focuses on speciation due to isolation in island-like settings, and the evolution of large-scale diversity as the result of origination, maintenance and extinction.
Biogeography and Ecology of Bulgaria
The book includes 22 chapters by 28 authors united by the single theme: biogeography and ecology of Bulgaria. From the single-celled organisms in the Black Sea sand to the endemic cave crustaceans, from the mountain glacial relict insects to the most diverse bird fauna in Europe, the unique fauna of Bulgaria has been a subject of study of mostly Bulgarian zoologists for more than a century. This is the first monograph in English broadly addressing all vertebrate and many key invertebrate groups of Bulgaria, their faunistics, origin, geographical and ecological distribution, and conservation issues are addressed by the experts on each group.
Bioethics in Cultural Contexts : Reflections on Methods and Finitude
This book discusses a range of methodological issues for an interdisciplinary bioethics. How can bioethics be an enterprise that does not only isolate issues and moral reasons but also (re)contextualises them? What are the strengths and weaknesses of different traditional and innovative modes of ethical work in terms of these tasks?
Bioequivalence of topical generic products
Bioequivalence (BE) assessment of topical dermatological products is a long standing challenge. The development of generic topical dermatological products has often been hampered due to the limited number of acceptable approaches, which are capable of determining the BE between generic products and reference list products. Currently, except in the case of dermatological corticosteroids, the golden rule to establish the BE of most topical dermatological products still heavily relied on clinical endpoint trials, which are often unreliable, time-consuming and expensive. The regulatory agencies and pharmaceutical industries are forging ahead to the development of new surrogate BE assessment approaches for other topical dermatological products. These promising approaches include dermatopharmacokinetic study (DPK), dermal microdialysis (DMD), near-infrared spectrometry (NIR), and confocal Raman spectroscopy (CRS).
Bioengineering in cell and tissue research
This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering.
Bioenergetics : Energy conservation and conversion
The present book addresses fundamental questions of biological energy transformation and conservation, with a focus on those processes which can now be understood on a structural basis.Current knowledge of selected examples of the biological energy conservation machinery such as cellular oxygen respiration, light-driven energy converters, and fermentation is reviewed. The machinery is highly variable, particularly that within microorganisms, but all of these devices universally rely on one unique underlying physico-chemical principle. The book is a rich source for specialists interested in recent developments in bioenergetics research and novices in the field alike.
Bioelectromagnetics current concepts : The mechanisms of the biological effect of extremely high power pulses
Proceedings of the NATO Advanced Research Workshop on The Mechanisms of the Biological Effect on Extra High Power Pulses (EHPP), Yerevan, Armenia 3 - 5 March 2005
Bioelectricity : A Quantitative Approach
"The authors’ goal in producing this book was to provide an introductory text to electrophysiology, based on a quantitative approach. In attempting to achieve this goal, therefore, the authors have opened the book with a useful, and digestible, introduction to various aspects of the mathematics relevant to this field, including vectors, introduction to Laplace, Gauss’s theorem, and Green’s theorem. This book will be useful for students in medical physics and biomedical engineering wishing to enter the field of electrophysiological investigation. It will also be helpful for biologists and physiologists who wish to understand the mathematical treatment of the processes and signals at the center of the interesting interdisciplinary field.
Bioeconomy and Global Inequalities Socio-Ecological Perspectives on Biomass Sourcing and Production
This book explores bioeconomy and bioenergy policies across South America, Asia and Europe. It discusses how a transition away from a fossil and towards a bio-based economic order alters, reinforces and challenges socio-ecological inequalities. A series of conceptual discussions and case studies with a multidisciplinary background in the Social Science illuminate how the deployment of biomass sources from the agricultural and forestry sectors affect societal changes concerning knowledge production, land and labour relations, political participation and international trade
Bioeconomy : Shaping the transition to a sustainable, biobased economy
This book defines the new field of "Bioeconomy" as the sustainable and innovative use of biomass and biological knowledge to provide food, feed, industrial products, bioenergy and ecological services. The chapters highlight the importance of bioeconomy-related concepts in public, scientific, and political discourse. Using an interdisciplinary approach, the authors outline the dimensions of the bioeconomy as a means of achieving sustainability.
Bioeconomic modelling and valuation of exploited marine ecosystems
This book offers an environmental-economic analysis of exploited ecosystems with a clear policy orientation. The study tries to move beyond traditional economic fishery analysis in two respects. First, several theoretical and numerical models are offered that combine economic and ecological descriptions of fisheries. These models give special attention to spatial processes as well as to combining exploitation and conservation objectives. Second, valuation and stakeholder concerns are addressed in empirical analyses employing both qualitative and quantitative approaches. The latter is done by using advanced methods of monetary valuation. In addition, the first part of the book presents short, introductory overviews of integrated assessment, economic modeling of fishery management, and incorporating uncertainty in fisheries analysis.
Biodiversity-health-sustainability Nexus in socio-ecological production landscapes and seascapes (SEPLS)
It is a compilation of case studies that provide useful knowledge and lessons that derive from on-the-ground activities and contribute to policy recommendations, focusing on the interlinkages between biodiversity and multiple dimensions of health (e.g., physical, mental, and spiritual) in managing socio-ecological production landscapes and seascapes (SEPLS). This book provides insights on how SEPLS approaches can contribute to more sustainable management of natural resources, achieving global biodiversity and sustainable development goals, and good health for all. It is also expected to offer useful knowledge and information for an upcoming three-year thematic assessment of “the interlinkages among biodiversity, water, food, and health” (the so-called “nexus assessment”) by the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES). The book begins with an introductory chapter followed by eleven case study chapters demonstrating the nexus between biodiversity, health, and sustainable development, and then a synthesis chapter clarifying the relevance of the case study findings to policy and academic discussions. It will be of interest to scholars, policymakers, and professionals in the field related to sustainable development.
Biodiversity of angola : Science & conservation : A modern synthesis
The book identifies Angola as one of the most biologically diverse countries in Africa, but notes that its fauna, flora, habitats and the processes that drive the dynamics of its ecosystems.
Biodiversity in Enclosed Seas and Artificial Marine Habitats ; Proceedings of the 39th European Marine Biology Symposium, held in Genoa, Italy, 21-24 July 2004
The main themes of the Symposium were biodiversity in enclosed and semi-enclosed seas and artificial habitats, and the restoration of degraded systems. These themes are highly relevant today both from a basic scientific point of view and from an applied approach. The papers dealing with the first theme represent current research and concerns about marine biodiversity in enclosed seas and will have wide appeal to all those interested in understanding and preserving the biodiversity of the seas and in particular of the Mediterranean and Black Seas. The papers in the second theme represent a synthesis of up-to-date knowledge on artificial habitats and how they can contribute to protection of coastal marine ecosystems, to enhancement of species diversity and biological resources and to restoration of degraded marine environments.
Biodiversity and Ecophysiology of Yeasts
In the last few decades more and more yeast habitats that were not investigated earlier, spanning cold climates to tropical regions and dry deserts to rainforests, have been explored. As a result, a large body of ecological data has been accumulated and the number of known yeast species has increased rapidly. This book provides an overview of the biodiversity of yeasts in different habitats. The recent advances achieved by the application of molecular biological methods in the field of yeast taxonomy and ecology are also incorporated in the book. Wherever possible, the interaction between yeasts and the surrounding environment is discussed.
Bioclimatic housing : Innovative designs for warm climates
In the search for sustainable architecture, there is growing interest in the relationship between nature and design. In this context, Bioclimatic Housing covers creative, vernacular architecture to present both the theory and practice of innovative, low-energy architecture.The book interweaves the themes of social progress, technological fixes and industry transformation within a discussion of global and country trends, climate types, solutions and technologies. this is a truly international and authoritative work, providing an essential primer for building designers, builders, developers and advanced students in architecture and engineering.
