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Chronic Lymphocytic Leukemia
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. developments of basic science into effective new approaches to the patient.
Chlorophylls and Bacteriochlorophylls : Biochemistry, Biophysics, Functions and Applications
This book summarizes the chemical, physical, biological and medical aspects of chlorophyll (and bacteriochlorophyll) research and development, with a focus on the tremendous progress achieved over the past 15 years. Each section has an up-to-date introductory overview which is followed by a series of concise well-focused and fully-referenced chapters written by experts in (bio)chemistry, (bio)physics, photobiology and photomedicine.
Chiral Diazaligands for Asymmetric Synthesis
The use of phosphine derivatives has historically induced the tremendous development of catalysis (both non-asymmetric and asymmetric). Although the chemistry of amines is more documented, the use of nitrogen-containing ligands only appeared recently. Nevertheless, during the last ten years, the results describing chiral diamine preparations and their uses in asymmetric catalysis and synthesis are increasing faster than their phosphorus counterparts. The reader will find in this volume the most recent methods for the synthesis of chiral diamines as well as their applications in asymmetric catalysis of CC bond formation. Particular attention will be given to spartein and derivatives of such diamines. Recently, the particular properties and the chemistry of amines allowed to obtain catalysts easy to separate and recycle and new types of ligands such as diaminocarbenes, ureas and thioureas. Finally, the complexing properties of some diamines allowed the formation of complexes with chirality "at the metal " which is of major theoretical interest and presents numerous potential applications.
Chinese Railways : Reform and Efficiency Improvement Opportunities
Although being huge by any measure, Chinese Railways are a bottleneck for economic growth in China. The state-owned enterprise returns a small profit but is severely capacity constrained and burdened with inefficiency. A comprehensive reform and efficiency improvement program needs to be developed in order to enable Chinese Railways to support further GDP growth in China. Application of industrial economics to the case of Chinese Railways suggests that moderate deregulation of e.g., the freight business could make Chinese Railways fit for future growth. Operational improvements need to complement this development, such as a redesign of the schedule or the introduction of value added services in the freight business. Based on interviews with Chinese experts, benchmarking with railways in the US, Germany, Russia, and Japan as well as broad coverage of Chinese-language sources, the book makes detailed recommendations on how to design a comprehensive turnaround program for Chinese Railways.
China's Long-Term Low-Carbon Development Strategies and Pathways : Comprehensive Report
This book introduces a multi-disciplinary and comprehensive research on China's long-term low-carbon emission strategies and pathways. After comprehensively considering China’s own socioeconomic conditions, policy design, energy mix, and other macro-development trends and needs, the research team has proposed suggestions on China’s low-carbon development strategies and pathways until 2050, with required technologies and policies in order to realize the goals of building a great modern socialist country and a beautiful China.
China's Energy Revolution in the Context of the Global Energy Transition
This book is an encyclopaedic analysis of the current and future energy system of the world’s most populous country and second biggest economy. What happens in China impacts the planet. In the past 40 years China has achieved one of the most remarkable economic growth rates in history. Its GDP has risen by a factor of 65, enabling 850,000 people to rise out of poverty.
China’s Gas Development Strategies
This book is open access under a CC BY 4.0 license. This book examines how China can increase the share of natural gas in its energy system. China’s energy strategy has global ramifications and impact, and central to this strategy is the country’s transition from coal to gas. The book presents the culmination of a two-year collaboration between the Development Research Center of the State Council (DRC) and Shell.
China and the World in a Changing Context : Perspectives from Ambassadors to China
This book aims to present an overview of China and the world from diverse angles. It brings together essays by ambassadors to China on a range of bilateral and multilateral issues, including trade and investment, regional economic cooperation, sustainable development, technology and innovation, and entrepreneurship. Given their familiarity with China and extensive international experience, the insights of these ambassadors are useful for policymakers, academics, entrepreneurs, students, and anyone trying to make sense of our rapidly changing world.
Children's rehabilitation center
الهدف من المشروع : 1 - الحاجة للمشروع بسبب العديد الكبير من الأطفال الفاقدين لذويهم وعائلاتهم في الحرب خلال السنوات التي مضت. 2 - إعادة صياغة الفراغات الداخلي من ابعاد ومفروشات تجاه الأطفال في المركز. 3 - استثارة الجانب الإبداعي للطفل وغرس مبادئ الفن فيه من خلال صفوف الموسيقا والفن التجريدي من خلال المركز.
Children's Exploration and Cultural Formation
This book examines the educational conditions that support cultures of exploration in kindergartens. It conceptualises cultures of exploration, whether those cultures are created through children’s own engagement or are demanded of them through undertaking specific tasks within different institutional settings.
Children's diabetes
Diabetes in infants, toddlers, older children, and adolescents poses serious physical, mental, and emotional challenges. Striking a balance among hypoglycemia/hyperglycemia, growth/development, and other life factors is not easy for health care providers, patients, or families. In addition, personal, family, or environmental conditions present before the onset of diabetes may compound the delicate balance needed to maintain good glycemic control. Therefore, there is a great need, especially at the time of initial diagnosis, to assess the developmental, behavioral, and psychosocial history of children with diabetes and their families.
Children and the Dark Side of Human Experience : Confronting Global Realities and Rethinking Child Development
Synthesizing insights from psychology and philosophy with his own wide-ranging, first-hand experiences around the world, Dr. James Garbarino takes readers on a personalized journey into the dark side of human experience as it is lived by children. In these highly readable pages, Dr. Garbarino intertwines a discussion of children’s material and spiritual needs with a detailed examination of the clinical knowledge and experiential wisdom required to understand and meet complex developmental needs. Fusing anecdotal observations, empirical evidence, and an ecological perspective, he reveals a path to ensuring the fundamental human rights of all children: the right to safety, to equality, to economic parity, and to a meaningful life.
Children and Peace : From Research to Action
This book's multi-layered emphasis on context, structural determinants of peace and conflict, and use of research for action towards social cohesion for children and youth has not been brought together in other peace psychology literature to the same extent. Children and Peace: From Research to Action will be a useful resource for peace psychology academics and students, as well as social and developmental psychology academics and students, peace and development practitioners and activists, policy makers who need to make decisions about the matters covered in the book, child rights advocates and members of multilateral organizations such as the UN.
Child Neuropsychology : Assessment and Interventions for Neurodevelopmental Disorders
Child Neuropsychology guides therapists and neurologists toward common goals: early, accurate diagnosis and finely focused interventions across disciplines. By analyzing the affects of brain development on children and adolescents’ behavioral, cognitive, learning, and psychosocial abilities and deficits, this groundbreaking volume brings vital perspectives to assessment and treatment. Leading experts Ellison and Semrud-Clikeman start with the basics of child clinical neuropsychology and functional neuroanatomy, taking readers through examination protocols and assessment instruments to treatment planning and methods. In this volume, the authors address the full range of neurodevelopmental pathologies, from learning disabilities to autism, ADHD to CNS disorders, traumatic brain injury to fetal alcohol syndrome.
Child Maltreatment and the Law: Returning to First Principles
Child Maltreatment and the Law is a must-read for psychologists, developmentalists, sociologists, social workers, criminologists, and researchers focusing on family life as well as policymakers and advocates working within the legal system. The book is particularly useful for courses relating to child welfare law or child abuse and neglect.
Chemokines and Viral Infection
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
Chemokine biology : Basic research and clinical application ; Vol.1 : Immunobiology of chemokines
The discovery of interleukin-8 close to 20 years ago initiated a new field of research touching on many aspects of immunology and inflammation. Interleukin-8 is just one member of a large class of structurally related chemoattractant proteins, known as chemokines. Chemokines are involved in the traffic control of leukocytes, which bear the corresponding chemokine receptors on their surfaces. Today, it is clear that chemokines affect all aspects of immunology and even many unrelated fields, such as tissue development and tumor cell metastasis. Their fundamental contributions to chronic inflammatory diseases make them a principal target for the development of novel, anti-inflammatory therapeutics.
Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences
Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process.
Chemistry of Biologically Potent Natural Products and Synthetic Compounds
Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.
Chemistry for the Protection of the Environment 4
This volume is the proceedings of the first CPE conference in the new millennium and the thirteenth in a well-established series of conferences on Chemistry for the Protection of the Environment, first established in 1976. With support of the U.S. EPA, the series of conferences provides an opportunity for interdisciplinary exchange of ideas among international specialists, from diverse fields and backgrounds, on the chemical aspects of environmental protection. Over the years, the CPE conferences have gathered participants from more and more countries, and the scope of interests have been broadened. Held in Hilo, Hawaii, this was the first of these international conferences to take place in the United States. The Organizing Committee attracted to the conference a wide range of talented scientists and engineers who have useful ideas to contribute on how to clean our environment.
