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Non-Covalent Multi-Porphyrin Assemblies : Synthesis and Properties
This book presents an overview of the synthesis, structure, and properties of molecules obtained by connecting several porphyrins or metalloporphyrins through a variety of chemical linkages. This handsomely produced book gives the reader a broad introduction to this popular and important field. Much of the work encompassed in this area is inspired by the desire to obtain photochemically responsive molecules capable of mimicking various aspects of photosynthesis… As with many edited volumes of this type, there is a certain amount of duplicate coverage of some topics. Also the focus is largely on the methods used to generate the multiporphyrin arrays, and in some cases less attention is given to the properties, other than the structural properties of these arrays.
Noncommunicable diseases
Focuses on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world’s biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs / (ii) the burden, epidemiology and priority interventions for individual NCDs / (iii) social determinants and risk factors for NCDs and priority interventions / (iv) global policy / (v) cross-cutting issues / and (vi) stakeholder action.
Nonblocking Supervisory Control of State Tree Structures
This monograph proposes how to manage complexity by organizing the system as a State Tree Structure (STS). an efficient recursive symbolic algorithm is presented that can perform nonblocking supervisory control design in reasonable time and memory for complex systems.
Nonblocking Electronic and Photonic Switching Fabrics
This state-of-the-art survey of switching fabric architectures gives special attention to combinatorial properties of switching fabrics – nonblockingness and rearrangeability. Also describing control algorithms proposed to control different architectures.
Nonbayesian Decision Theory : Beliefs and Desires as Reasons for Action
This book aims to present an account of rational choice from a non-Bayesian point of view. Rational agents maximize subjective expected utility, but contrary to what is claimed by Bayesians, the author argues that utility and subjective probability should not be defined in terms of preferences over uncertain prospects. To some extent, the author’s non-Bayesian view gives a modern account of what decision theory could have been like, had decision theorists not entered the Bayesian path discovered by Ramsey, Savage, and Jeffrey. The author argues that traditional Bayesian decision theory is unavailing from an action-guiding perspective. For the deliberating Bayesian agent, the output of decision theory is not a set of preferences over alternative acts - these preferences are on the contrary used as input to the theory.
Noise-Induced Phenomena in Slow-Fast Dynamical Systems : A Sample-Paths Approach
Stochastic differential equations play an increasingly important role in modeling the dynamics of a large variety of systems in the natural sciences, and in technological applications. This book presents a new constructive approach to the quantitative description of solutions to systems of stochastic differential equations evolving on well-separated timescales. The method, which combines techniques from stochastic analysis and singular perturbation theory, allows the domains of concentration for typical sample paths to be determined, and provides precise estimates on the transition probabilities between these domains. In addition to the detailed presentation of the set-up and mathematical results, applications to problems in physics, biology, and climatology are discussed. The emphasis lies on noise-induced phenomena such as stochastic resonance, hysteresis, excitability, and the reduction of bifurcation delay.
NMR in Biological Systems : From Molecules to Human
During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book caters to the needs of: (i) graduate students who mostly learn such techniques from senior post-docs in the laboratory; (ii) those who are not experts in NMR but wish to understand if a particular problem in animal, plant, medical and pharmaceutical sciences can be answered by NMR; and (iii) those who are experts in chemistry and biochemistry and wish to know how NMR can provide them information on structural or functional aspect of proteins, nucleic acids, cells and tissues, human and plant organs and other biological materials.
NMR - From Spectra to Structures : An Experimental Approach
Nuclear magnetic resonance spectroscopy is one of the most powerful analytical methods. This practice-oriented textbook aims at teaching how NMR experiments should be used to make structural asssignments. The book is intended as a practical guide for students and laboratory personnel, so that the emphasis is on practical rather than on theoretical aspects, which are treated only to the extent necessary to understand the experiments and to interpret the results.The second edition has been expanded to include several other heteronuclei (15N, 19F, 29Si, 77Se, 113Cd, 117Sn/119Sn, 195Pt, 207Pb) and a new chapter on solid state NMR. The problems section has been enlarged and now includes 50 problems.
NL ARMS Netherlands Annual Review of Military Studies 2020 : Deterrence in the 21st Century—Insights from Theory and Practice
This book surveys the state of the field to examine whether a fifth wave of deterrence theory is emerging. Bringing together insights from world-leading experts from three continents, the volume identifies the most pressing strategic challenges, frames theoretical concepts, and describes new strategies.
Nitrogen-fixing Leguminous Symbioses
This book is the self-contained final volume of a comprehensive seven-volume series covering the basic and applied science relating to nitrogen fixation. It addresses the most important nitrogen-fixing symbiosis of all – that between legumes and their root-nodule bacteria – and therefore deals with the properties and behaviour of both macro- and micro-symbiont.
Nitrogen-fixing Actinorhizal Symbioses
This book is the self-contained sixth volume of a comprehensive series on nitrogen fixation. It presents the state-of-the-art in regards to actinorhizal symbioses. Like legumes, actinorhizal plants form root nodules that host nitrogen-fixing soil bacteria. However, because the macrosymbionts are, with one exception, woody plants rather than crop plants, actinorhizal symbioses are less well-known than legume symbioses to which they are phylogenetically related. Actinorhizal plants come from eight different families. This volume includes chapters that deal with all these aspects of the symbiosis and both symbionts plus their ecological role and use. Other chapters tackle the global distribution of different actinorhizal plants and their microsymbionts and how this impacts the question of co-evolution of the micro- and macrosymbionts as well as comparing the actinorhizal and leguminous symbioses.
Nitrogen Fixation in Agriculture, Forestry, Ecology, and the Environment
Sustainability has a major part to play in the global challenge of continued development of regions, countries, and continents all around the World and biological nitrogen fixation has a key role in this process. This volume begins with chapters specifically addressing crops of major global importance, such as soybeans, rice, and sugar cane. It continues with a second important focus, agroforestry, and describes the use and promise of both legume trees with their rhizobial symbionts and other nitrogen-fixing trees with their actinorhizal colonization. An over-arching theme of all chapters is the interaction of the plants and trees with microbes and this theme allows other aspects of soil microbiology, such as interactions with arbuscular mycorrhizal fungi and the impact of soil-stress factors on biological nitrogen fixation, to be addressed. Furthermore, a link to basic science occurs through the inclusion of chapters describing the biogeochemically important nitrogen cycle and its key relationships among nitrogen fixation, nitrification, and denitrification. The volume then provides an up-to-date view of the production of microbial inocula, especially those for legume crops.
Nitrogen Cycling in the Americas : Natural and Anthropogenic Influences and Controls
The rate of creation of reactive nitrogen (NR) on the earth has dramatically increased in the last half century mainly due to the production of N-fertilizer through the Haber-Bosch process, fossil fuel combustion, and the cultivation of plants that fix N from the atmosphere. The anthropogenic production of NR has been especially high in developed countries of the temperate zone, such as the USA and Canada, where severe eutrophication of estuaries and coastal zones, acidification of lakes and streams, loss of biodiversity, and reduced forest productivity have become common environmental problems associated with increasing nitrogen loads to ecosystems. This book presents a series of studies from across the Americas whose aim is to highlight key natural processes that control nitrogen cycling as well as discuss the main anthropogenic influences on the nitrogen cycle in both the tropical and temperate regions of the Americas.
Nitric oxide in plants : A molecule with dual roles
Studies have identified the central role of nitric oxide in stress mitigation through the modulation of physiological and biochemical pathways including germination, photosynthesis regulation, and programmed cell death. Nitric Oxide in Plants: A Molecule with Dual Roles provides a detailed account of the physio-biochemical, molecular, and omic basis of NO-mediated responses in crop plants under different stresses.
Nitric Oxide in Plant Growth, Development and Stress Physiology
The first part of the book is devoted to the description of key features related to NO biochemistry, synthesis and metabolism and the modes of action involved. The second part covers the functionality of NO in three central nodes of the plant life cycle: growth, development and stress physiology.
Nine algorithms that changed the future : The ingenious ideas that drive today’s computers
Every day, we use our computers to perform remarkable feats. A simple web search picks out a handful of relevant needles from the world’s biggest haystack. Uploading a photo to Facebook transmits millions of pieces of information over numerous error-prone network links, yet somehow a perfect copy of the photo arrives intact. Without even knowing it, we use public-key cryptography to transmit secret information like credit card numbers, and we use digital signatures to verify the identity of the websites we visit. How do our computers perform these tasks with such ease?
Nimesulide - Actions and Uses
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs.
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
N-Heterocyclic Carbenes in Transition Metal Catalysis
It was only in the early 1990s that carbenes with the carbene carbon being incorporated in a nitrogen containing heterocycle (N-heterocyclic carbenes or NHCs) were found to be stable enough to be isolated. Since the first report on the application of NHCs as ligands in transition metal catalysis in 1995, NHC have found numerous applications and have been established as a versatile and indispensable class of ligands. For many reactions like metathesis or cross-coupling reactions NHCs have often become the ligands of choice, allowing otherwise difficult transformations. In this book leading experts have surveyed major areas of application of NHC metal complexes in catalysis. The authors have placed a special focus on nickel- and palladium-catalyzed reactions, on applications in metathesis reactions, on oxidation reactions and on the use of chiral NHC-based catalysts. This compilation is rounded out by an introductory chapter and a chapter dealing with synthetic routes to NHC metal complexes.
NF-kB/Rel Transcription Factor Family
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
