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Clinical MR Imaging : A Practical Approach
This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized.
Clinical Functional MRI : Presurgical Functional Neuroimaging
Functional magnetic resonance imaging (fMRI) has contributed significantly to progress in neuroscience by permitting noninvasive imaging of the "human brain at work" under physiological conditions. Within clinical neuroimaging, fMRI is opening up a new diagnostic field by measuring and visualizing brain function. However, fMRI is not yet a standard diagnostic imaging procedure. This textbook is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions in individual patients, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery.
Classic Papers in Critical Care
Every medical specialty has at its basis a core of classic papers, which both reflect the historical background and give insight into present and future developments. The papers discussed in this book are considered classics for many reasons, but in all cases they highlight landmarks in the development in critical care medicine and therefore providing an invaluable reference for both trainee and practising clinicians.
Cilia : Methods and protocols
Covers the latest advancements in the study of ciliary complexity. Protocols cover genomic, proteomic, imaging, and functional analysis of different ciliated tissues and their wide applicability in cilia biology. Chapters in this book primarily focus on methods to study multiciliated cells, and discuss topics such as SARS-CoV-2 infections of human primary nasal multiciliated epithelial cells; expansion microscopy of ciliary proteins; live-imaging centriole amplification in mouse brain multiciliated cells; biophysical properties of cilia motility; and mucociliary transport device construction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Child Neuropsychology : Assessment and Interventions for Neurodevelopmental Disorders
Child Neuropsychology guides therapists and neurologists toward common goals: early, accurate diagnosis and finely focused interventions across disciplines. By analyzing the affects of brain development on children and adolescents’ behavioral, cognitive, learning, and psychosocial abilities and deficits, this groundbreaking volume brings vital perspectives to assessment and treatment. Leading experts Ellison and Semrud-Clikeman start with the basics of child clinical neuropsychology and functional neuroanatomy, taking readers through examination protocols and assessment instruments to treatment planning and methods. In this volume, the authors address the full range of neurodevelopmental pathologies, from learning disabilities to autism, ADHD to CNS disorders, traumatic brain injury to fetal alcohol syndrome.
Chemical Biology of Neurodegeneration : A Molecular Approach
This book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes?from a biochemical point of view?the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered.
Changing Aspects in Stroke Surgery : Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass
What is arterial dissection? What is Moyamoya angiopathy? What is the state of art of AVM treatment? Readers will find answers to these questions in this book. But they will also be informed about the state of the art treatment in the daily stroke therapy.
Cerebral vasospasm : New strategies in research and treatment
More than 90 papers give a summary of clinical and basic studies on cerebral vasospasm, including reviews by leading researchers in this field. Several new frontiers are proposed for future research directions that will not only promote research from neurosurgery and neurology but also from other interconnecting fields of emergency medicine, electrophysiology, molecular biology, and vascular biology.
Cerebral monitoring in the OR and ICU
This comprehensive volume will serve as a complete guide to the clinical application of computer assisted systems in monitoring central nervous functions both in the OR and ICU. It presents practical guidelines and therapeutic indications for computerized EEG and Somatosensory Evoked Potential (SSEP) monitoring for the experienced user and the novice. The book also describes what cerebral monitoring can do and what its limitations are.
Cerebral Hemorrhage
Cerebral hemorrhage is a common and often fatal subtype of stroke. while in the past it has received relatively little attention compared to ischemic stroke, there have been major advances in our understanding of this devastating form of stroke. The papers by world experts cover the field from molecular biology to clinical trials.
Cell-Cell Channels
The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
Cell Therapy, Stem Cells and Brain Repair
As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones.
Causality of Psychological Injury : Presenting Evidence in Court
This sequel to the authors’ Psychological Knowledge in Court offers a welcome expansion on key concepts, terms, and issues in causality, bringing much needed clarity to psychological injury assessments and the legal contexts that employ them. Focusing on PTSD, traumatic brain injury, and chronic pain (and grounding readers in salient U.S. and Canadian case law), Causality sets out a multifactorial causality framework to facilitate admissibility of psychological evidence in court. Issues concerning malingering are examined in depth, as are clinical gray areas that can jeopardize validity. At the same time, the book clearly explains what lawyers and clinicians need to understand about each other’s work—of crucial importance since the two sides often seem to speak at cross-purposes.
Cannabinoids and the brain
Cannabinoids and the Brain gives a comprehensive overview of all the essential literature concerning the endocannabinoid and related systems in the nervous tissue. It is a rapidly expanding research field and the widespread presence of cannabinoids in most physiopathological mechanisms appear to hinder the effort to fully cover the subject. By the end of the book, the reader will have a solid knowledge of the genetics, molecular biology, anatomy, pharmacology, and physiology of the endocannabinoid system and its involvement in neurological and psychiatric disorders, and will eventually discover a natural relationship among marijuana, aspirin, and chili pepper.
Business partner management : Successfully managing external and internal business relationships
Provides a structured, industry-independent and at the same time practical insight into all types of business partnerships. Both relationships with external business partners and internal partnerships with colleagues and employees are considered in depth. The focus is on people as partner and individual with interests and goals. The comparison to private partnerships is quite intentional and illustrates the explanations. Findings from brain research, learning and cooperation are also included.
Brodmann's : Localisation in the Cerebral Cortex
It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.
Breathing, feeding, and neuroprotection
New findings in brain research are being revealed on an almost daily basis, and the focus of this book is the fields of breathing, neuroprotection, and higher brain functions. An unresolved issue within respiration research and hence a topic of much interest is Where and how respiratory rhythm is generated in the brainstem, detailed analysis of which is presented herein. Chapters on neuroprotection examine the functional significance of the blood – brain barrier as an interface of blood and the central nervous system; other chapters look at health and disease in relation to the hypothalamic and limbic systems. In addition to animal experiments, research on the human brain is included, with a focus on the recently developed EEG/dipole tracing method. This book will be an invaluable reference for researchers in neuroscience and related fields.
Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries ; 7th International Workshop, BrainLes 2021, Held in Conjunction with MICCAI 2021, Virtual Event, September 27, 2021, Revised Selected Papers, Part I
The content of thebook covers the current state-of-the-art literature on federated learning applications for cancer research and Vclinical oncology analysis, as well as an overview of the deep learning approaches improving the current standard of care for brain lesions and current neuroimaging challenges. It is also focusing on the accepted BrainLes workshop submissions, is to provide an overview of new advances of medical image analysis in all the aforementioned brain pathologies. It brings together researchers from the medical image analysis domain, neurologists, and radiologists working on at least one of these diseases. The aim is to consider neuroimaging biomarkers used for one disease applied to the other diseases.
Brain-inspired computing ; 4th International Workshop, BrainComp 2019, Cetraro, Italy, July 15–19, 2019, Revised Selected Papers
The 11 papers presented in this volume were carefully reviewed and selected for inclusion in this book. They deal with research on brain atlasing, multi-scale models and simulation, HPC and data infra-structures for neuroscience as well as artificial and natural neural architectures.
Brain-computer interfaces : An international sssessment of research and development trends
This WTEC study gathered information on worldwide status and trends in BCI research to disseminate to government decisionmakers and the research community. The study reviewed and assessed the state of the art in sensor technology, the biotic-abiotic interface and biocompatibility, data analysis and modeling, hardware implementation, systems engineering, functional electrical stimulation, noninvasive communication systems, and cognitive and emotional neuroprostheses in academic research and industry.
